scholarly journals Pathogenetic significance of the male factor in an uncompleted pregnancy

2021 ◽  
Vol 20 (3) ◽  
pp. 27-32
Author(s):  
E. V. Kudryavtseva ◽  
N. N. Potapov ◽  
V. V. Kovalev
Keyword(s):  
Chronic Diseases ◽  
Chromosomal Abnormalities ◽  
Married Couple ◽  
Married Couples ◽  
Control Group ◽  
Male Factor ◽  
Pregnancy Failure ◽  
History Of ◽  
Group 2 ◽  
Group 1

Introduction. When pregnancy failure occurs, not only the woman should be examined, but also her partner. Purpose of the study — to evaluate the significance of spermogram values in the partners of patients with an uncompleted pregnancy. Materials and methods. A retrospective comparative cohort study was conducted. A total of 197 married couples were ncluded in the study. Group 1 consisted of 71 couples with a history of miscarriag. Chromosomal abnormalities (CA) were detected during embryo cytogenetic examination in 45 cases; these patients were included in subgroup 1a; the rest constituted subgroup 1b. The control group (group 2) consisted of 126 couples without a history of pregnancy loss. A detailed anamnesis and general clinical examinations were performed in all the couples. Spouses of the patients underwent spermogram analysis. Results. The proportion of men who abused alcohol was higher in group 1 than in group 2 — 40.8% vs. 19% (p<0.01). In subgroup 1b chronic diseases were noted in 61.5% of men, in group 2 — only 28.6% (p<0.001). Differences in the number of men with normal spermogram were found between group 2 and subgroup 1b, 65.1% and 35.3%, respectively (p=0.036). In group 1, 45% of men had teratozospermia (43.5% in subgroup 1a, 47.1 in subgroup 1b) and in group 2, only 16.3% (p=0.004). Discussion. In most cases, the leading etiological factor in pregnancy failure is a chromosomal abnormality n the embryo (fetus). The role of the "male" factor is increasing in the genesis of pregnancy failure. Examination of thspouse should be an integral component of pre-conceptional preparation. Conclusion. Spousal alcohol abusrisk factor for CA in the embryo and for pregnancy failure. The presence of chronic diseases in the spouse is also a risk factor for pregnancy failure. Among the spermogram parameters, the number of spermatozoa with normal morphology is the most significant in assessing the ririsk of pregnancy failure in a married couple, teratozoospermia significantly increases the risk of non-pregnancy.

Dysregulatory visceropathies in patients with uterine endometriosis and recurrent endometrial hyperplasia

1986 ◽  
Vol 67 (5) ◽  
pp. 347-349
Author(s):  
N. I. Petrushkova
Keyword(s):  
Endometrial Hyperplasia ◽  
Digestive System ◽  
Practical Significance ◽  
Control Group ◽  
Liver And Pancreas ◽  
Rational Therapy ◽  
History Of ◽  
Group 2 ◽  
Digestive Glands ◽  
Group 1

The study of neurohormonal-visceral relationships in patients with uterine endometriosis is of practical significance in the development of rational therapy and prevention of this complex and rather frequent pathology. This study was aimed to investigate the functional state of the digestive glands of the stomach, intestines, liver and pancreas in 152 patients with uterine internal endometriosis (Group 1) and in 50 patients with recurrent endometrial hyperplasia (Group 2). Twenty healthy women were the control group. Patients with no history of diseases of the digestive system were selected for the examination.

Psychiatric Morbidity in Sentenced Segregated HIV-Positive Prisoners

1993 ◽  
Vol 163 (6) ◽  
pp. 802-805 ◽  
Author(s):  
Arthur Dorman ◽  
Art O'Connor ◽  
Eamonn Hardiman ◽  
Aideen Freyne ◽  
Helen O'Neill
Keyword(s):  
Drug Abuse ◽  
Matched Control ◽  
Psychiatric Morbidity ◽  
Hiv Positive ◽  
Control Group ◽  
Matched Control Group ◽  
History Of ◽  
The Mean ◽  
Group 2 ◽  
Group 1

In this comparative study with a control group of prisoners, psychiatric morbidity was measured in two groups of sentenced prisoners, each group completing the GHQ-30 and 21-item Beck Depression Inventory (BDI). Group 1 consisted of 40 segregated HIV-positive prisoners and group 2 a matched control group in the main prison who had no history of HIV seropositivity. All members of group 1 had a history of intravenous drug abuse. The mean GHQ-30 and BDI scores were significantly higher in group 1, and 90% of group 1 were psychiatric ‘cases’ compared with just over 42% of group 2. Levels of psychiatric morbidity present in a third group, consisting of HIV-positive prisoners who had not been segregated (prison authorities were unaware of their seropositivity) are an interesting pointer for further research.

scholarly journals Comparison of different cephalometric variables in patients with and without history of snoring

2017 ◽  
Vol 5 (12) ◽  
pp. 5283
Author(s):  
Azhar Khan ◽  
Mohamad Imran ◽  
Mohammed Imran ◽  
Shoib N. Parkar ◽  
Mueed U. Islam ◽  
...  
Keyword(s):  
Hyoid Bone ◽  
Sleep Apnea Syndrome ◽  
Sleep Apnoea ◽  
Control Group ◽  
Mandibular Plane ◽  
Obstructive Sleep ◽  
High Prevalence ◽  
History Of ◽  
Group 2 ◽  
Group 1

Background: Obstructive sleep apnea syndrome has a high prevalence among adults. Cephalometric variables can be a valuable method for evaluating patients with this syndrome. The objective of this study is to evaluate and compare the craniofacial variables in subjects with and without snoring by cephalometric analysis.Methods: 40 patients were included in the study who were divided into two groups; group 1 of 20 snoring patients and group 2 control group of 20 non-snoring patients and were evaluated and compared for various cephalometric variables.Results: The distance from the hyoid bone to the mandibular plane (MP-H) was the only variable that showed a statistically significant correlation between two groups.Conclusions: Cephalometric variables are useful tools for evaluating the patients with snoring who are predisposed to obstructive sleep apnoea. The distance from the hyoid bone to the mandibular plane showed a statistically significant correlation between two groups.

Relationship of Allergy, Enuresis, and Urinary Infection in Children 4 to 7 Years of Age

PEDIATRICS ◽  
1976 ◽  
Vol 57 (4) ◽  
pp. 526-528
Author(s):  
Sharon Siegel ◽  
Leslie Rawitt ◽  
Burton Sokoloff ◽  
Bernard Siegel
Keyword(s):  
Family History ◽  
Statistical Difference ◽  
Urinary Infection ◽  
Respiratory Allergy ◽  
Control Group ◽  
History Of ◽  
Group 2 ◽  
And Control ◽  
Day Wetting ◽  
Group 1

A group of 234 children, 4 to 7 years old, in a middle- to upper-middle-class Caucasian population, were divided into four groups and matched for age and sex. Group 1 consisted of 50 children previously treated for urinary infection; control group 1 contained 55 well children; group 2 consisted of 69 children treated for respiratory allergy; and control group 2 contained 60 well children. There was no statistical difference in persistent enuresis (night wetting every week), persistent day wetting (every week), allergy, or family history of enuresis, when group 1 and control group 1 were compared. A family history of urinary infection was higher (P &lt; .05) in group 1. There was no statistical difference in persistent enuresis, persistent day wetting, previous urinary infection, or family history of enuresis or urinary infection when group 2 and control group 2 were compared. This study suggests that there is no relationship between respiratory allergy, enuresis, and urinary infection.

The aetiology and influence of age and gender on the development of advanced chronic venous insufficiency in the population of patients of semi-urban county outpatient vascular clinic in Poland

2010 ◽  
Vol 26 (2) ◽  
pp. 56-61 ◽  
Author(s):  
Ł Dzieciuchowicz ◽  
Z Krasiński ◽  
K Motowidlo ◽  
M Gabriel
Keyword(s):  
Chronic Venous Insufficiency ◽  
Venous Insufficiency ◽  
Varicose Veins ◽  
Severe Trauma ◽  
Control Group ◽  
Age And Gender ◽  
History Of ◽  
Group 2 ◽  
And Gender ◽  
Group 1

Objective To determine the aetiology and influence of age and gender on the development of advanced chronic venous insufficiency in patients of semi-urban county outpatient vascular clinic. Methods One hundred and fourteen patients with venous ulcers were divided, based on the ultrasound examination, into group 1 or group 2, with or without post-thrombotic lesions in the deep venous system, respectively. The control group consisted of 352 patients with varicose veins and without leg ulceration. The demographic data and thrombotic risk factors were compared between the groups. Results Group 1 patients ( n = 109) were older than group 2 patients ( n = 5) and control group patients, 64.7 versus 47.2 years ( P = 0.016) and versus 53.8 years ( P < 0.001), respectively. The percentage of women did not differ between group 1 and the control group, but was lower in group 2 ( P = 0.01). The history of lower limb fracture or severe trauma increased the risk of post-thrombotic syndrome (PTS) in patients with venous ulcer. Conclusion In the population studied, the venous leg ulcer develops mainly due to primary varicose veins and its risk increases with age and is equal for both sexes. PTS should be suspected in younger patients with a history of severe trauma or leg fracture.

scholarly journals Specificities of small airways dysfunction development in patients with mild asthma

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Elena E. Mineeva ◽  
Marina V. Antonyuk ◽  
Alla V. Yurenko ◽  
Tatyana A. Gvozdenko ◽  
Oksana Yu. Kytikova
Keyword(s):  
Family History ◽  
Allergic Diseases ◽  
Mild Asthma ◽  
Control Group ◽  
Bronchial Obstruction ◽  
Small Airways ◽  
Asthma Patients ◽  
History Of ◽  
Group 2 ◽  
Group 1

The study goal was to identify specificities of small airways dysfunction development (SAD) in patients with mild asthma. Material and Methods — The study involved 114 patients with mild asthma. Depending on the condition of their small airways, the patients were split among two groups: Group 1 of 94 patients with asthma without SAD (82.5%); Group 2 of 20 patients with asthma and SAD (17.5%). The control group consisted of 25 volunteers. SAD was diagnosed by the presence of air trapping and hyperinflation. Results — SAD was diagnosed in 17.5% of patients with mild asthma. The development of SAD was observed in 80% of asthma patients with ailment duration of over 5 years and family history of asthma. Obesity was diagnosed 1.7 times more often in patients with SAD compared with those without it. Food allergy, allergic rhinitis, allergic conjunctivitis, urticaria and bronchial obstruction were identified two or more times more often in patients with SAD compared with those without it. Among all patients with mild asthma and SAD, bronchial obstruction was detected in 55% of cases. Conclusion — The development of SAD in the presence of mild asthma is characteristic for patients with ailment duration over 5 years, family history of asthma, obesity, predominant sensitization to food allergens, and concomitant non-pulmonary allergic diseases. Bronchial obstruction is not the obligatory feature of SAD development in presence of mild asthma.

Otitis media with effusion in children and its association with deformity of the vomero-ethmoid suture

1983 ◽  
Vol 97 (3) ◽  
pp. 203-212 ◽  
Author(s):  
W. D. McNicoll
Keyword(s):  
Otitis Media ◽  
Surgical Intervention ◽  
Otitis Media With Effusion ◽  
Head Injuries ◽  
Control Group ◽  
Secretory Otitis Media ◽  
Surgical Interventions ◽  
History Of ◽  
Group 2 ◽  
Group 1

AbstractFifty children aged between five and eight years of age who have had proven otitis media with effusion have been retrospectively assessed. Twenty-five children who had attended the Casualty Department with head injuries, who have had X-radiography of their skulls as part of their investigation, acted as controls. All the children in this group were selected because they had no otological history.The 50 Children comprising the retrospective survey were split into two groups: Group 1, with recurrent secretory otitis media requiring surgical intervention on more than three occasions; Group 2, comprising 25 children who had had up to three surgical interventions.All the children had PA X-radiography of their skulls in order to demonstrate the bony nasal septum. In Group 1, a septal deformity was found to be sited at the middle third of the bony septum at the vomero-ethmoid suture. In Group 2, the deformity was found to involve the whole of the middle third of the bony septum, plus portions of the upper and lower thirds of the bony septum.In the control group, in whom there was no history of otological disease, there was no deformity sited at the middle third of the bony septum.

scholarly journals Dynamics of brain CD68+ and stabilin-1+ macrophage infiltration in patients with myocardial infarction

Kardiologiia ◽  
2019 ◽  
Vol 59 (4S) ◽  
pp. 44-50
Author(s):  
M. S. Rebenkova ◽  
A. E. Gombozhapova ◽  
Yu. V. Rogovskaya ◽  
V. V. Ryabov ◽  
Yu. G. Kzhyshkowska ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Temporal Dynamics ◽  
Immunohistochemical Analysis ◽  
Control Group ◽  
Type I ◽  
Positive Correlation ◽  
History Of ◽  
Group 2 ◽  
The Brain ◽  
Group 1

Te aim of the study was to evaluate the temporal dynamics of brain CD68+ and stabilin-1+ macrophage infltration in patients with fatal myocardial infarction (MI) type 1.Materials and Methods. Te study included 31 patients with fatal MI type I. Te control group comprised 10 patients of 18–40 age group who died from injuries incompatible with life. Patients with MI were divided into two groups. Group 1 comprised patients who died during the frst 72 hours of MI, group 2 comprised patients who died on days 4‒28. Macrophage infltration in the brain was assessed by immunohistochemical analysis. We used CD68 as a marker for the cells of the macrophage lineage and stabilin-1 as an M2-like macrophage biomarker.Results. In group 1 the number of brain CD68+ macrophages was signifcantly higher than in the control group. In group 2 the intensity of brain CD68+ cells infltration was lower than in group 1 and higher than in the control group. Tere was a small amount of stabilin-1+ macrophages in the brain of healthy people, as well as of patients who died from MI. Tere were no signifcant differences in the number of stabilin-1+ cells between group 1 and group 2. Correlation analysis revealed the presence of positive correlation between the number of CD68 + macrophages in the infarct, peri-infarct, and non-infarct areas of the myocardium and the number of CD68+ macrophages in the brain in patients with MI. Tere were not correlations between the number of CD68 + and stabilin-1+ cells and the presence of diabetes mellitus, history of stroke, history of MI, and pre-infarction angina.Conclusion. Te number of brain CD68+ macrophages signifcantly increased during the frst three days of MI. Te number of brain stabilin-1+ macrophages did not increase and did not differ from the control values. We observed a positive correlation between the number of CD68+ macrophages in the brain and myocardium.

scholarly journals Central Corneal Thickness Measurements in Nonarteritic Anterior Ischemic Optic Neuropathy Patients: A Controlled Study

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Haneen Jabaly-Habib ◽  
Modi Naftali ◽  
George Habib
Keyword(s):  
Optic Neuropathy ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Ischemic Optic Neuropathy ◽  
Controlled Study ◽  
Control Group ◽  
Ischemic Optic Neuropathy ◽  
History Of ◽  
Group 2 ◽  
Group 1

Purpose. To measure central corneal thickness (CCT) in patients with history of nonarteritic anterior ischemic optic neuropathy (NAION).Patients and Methods. Patients older than 40 years with a history of NAION (group 1) were prospectively evaluated including full eye examination and central corneal thickness (CCT) pachymetry. Patients with a history of intraocular surgery, corneal disease, glaucoma, and contact lens wear were excluded. Measurements were also performed in a gender and age matched control group (group 2).Results. Thirty-one eyes of 31 NAION patients in group 1 were included and 30 eyes of 30 participants in group 2. There were 15 men in group 1 and 9 in group 2P=0.141, and mean age of the patients was59±10years in group 1 versus61±11years in group 2P=0.708. Mean CCT was539±30microns in group 1 and550±33microns in group 2P=0.155.Conclusion. Patients with NAION have no special characteristic of CCT in contrast to the crowded optic disc known to be a significant anatomic risk factor for NAION. More studies should be carried out to investigate CCT and other structure related elements in NAION patients.

Antiurolithiatic effect of Cymbopogon Proximus, Alhagi Maurorum, on Sulfadimidine induced urolithiasis in male New Zealand rabbits

2019 ◽  
Vol 20 (1) ◽  
pp. 12-18
Author(s):  
Sameh El-Nabtity
Keyword(s):  
New Zealand ◽  
Intramuscular Injection ◽  
Negative Control Group ◽  
Negative Control ◽  
Control Group ◽  
Aqueous Extracts ◽  
Blood And Urine Samples ◽  
Group 2 ◽  
New Zealand Rabbits ◽  
Group 1

The present study aimed to investigate the prophylactic effect of Cymbopogon proximus and Alhagi maurorum on Sulfadimidine induced urolithiasis in rabbits . Thirty New Zealand male rabbits were allocated into six equal groups (each of five): Group (1) was used as a negative control. Group(2) were administered sulfadimidine (200mg/kg) by intramuscular injection.Groups(3) and (4) were administered sulfadimidine(200mg/kg) by intramuscular injection and 330mg/kg of Cymbopogon proximus alcoholic and aqueous extracts respectively orally.Groups(5) and (6) were administered sulfadimidine(200mg/kg) by intramuscular injection and 400mg/kg of Alhagi maurorum alcoholic and aqueous extracts respectively orally. The period of experiment was 10 days. Blood and urine samples were collected from rabbits on the 10th day. The results recorded a significant decrease in serum creatinine, urea, uric acid and crystalluria in Cymbopogon proximus and Alhagi maurorum groups compared to sulfadimidine treated group.We conclude that Cymbopogon proximus and Alhagi maurorum have a nephroprotective and antiurolithiatic effects against sulfadimidine induced crystalluria.

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