Treatment of Rajo-Nivrutti Janya Lakshana by Medhya Ghrita Nasya

2020 ◽  
Vol 8 (01) ◽  
Author(s):  
Pooja Bavaskar
Keyword(s):  
Total Effect ◽  
Effect Of Therapy ◽  
Diseased Condition ◽  
Almost All

For a woman “Rajah” is a very important factor. Shuddha Rajah or Artava is a sign of Dhatuparipurnata. In Ayurveda, Rajonivrutti is not described as a diseased condition. Almost all Acharya have described the age of Rajonivrutti as approximately 50 years without any controversy. The majority of the Lakshanas of Oajonivrutti are due to Vata Vriddi, Kapha Kshaya, Ashayapakarsha of Pitta by aggravated vata; vitiation of Manovaha Strotas; and Dhatukshaya, Which all are manifesting as a part of aging. The diagnosis was carried out on the basis of various symptoms. On the basis of criteria of assessment adopted, Medhya Grita Nasya the total effect of therapy has been carried out.

Effect of drugs in secondary disease progression in patients with multiple sclerosis

2004 ◽  
Vol 10 (3_suppl) ◽  
pp. S46-S55 ◽  
Author(s):  
Ludwig Kappos
Keyword(s):  
Multiple Sclerosis ◽  
Disease Progression ◽  
Progressive Multiple Sclerosis ◽  
Positive Effects ◽  
Secondary Progressive ◽  
The North ◽  
Disability Status ◽  
Relapsing Remitting ◽  
Effect Of Therapy ◽  
Almost All

Secondary progressive multiple sclerosis (SPMS) is a form of MS characterized by continuously worsening disability with or without superimposed relapses that occurs after a variable period of relapsing remitting disease and results in limited ambulation for almost all patients. The use of interferon beta (IFN b) for immunomodulation in patients with SPMS has been evaluated in four recent clinical trials: The European multicentre trial on IFN b-1b in SPMS (EUSPMS), the Secondary Progressive Efficacy Trial of Rebif (IFN b-1a) in MS (SPEC TRIMS), the North A merican Study of IFN b-1b in SPMS (NA SPMS), and the Internatio nal MS Secondary Progressive Avonex C linical Trial (IMPAC T). EUSPMS was the only trial to demonstrate a significant positive effect of therapy on disease progression as measured by the expanded disability status scale (EDSS). However, results from all studies demonstrated significant positive effects of treatment on relapse, T2 lesion load, and gadolinium enhancement. Immunomodulation with IFN b has the potential to significantly slow disease progression and improve quality of life for patients with SPMS. While results with monthly IV Ig were disappointing, positive effects on disease progression have been reported with the applicatio n of immunosuppressants, especially Mitoxantrone. The risk-benefit ratio of these cytostatic agents remains controversial. New strategies addressing the important neurodegenerative aspects of the disease are urgently needed.

scholarly journals CLASSICAL UTILITY OF PANCHATIKTA GUGGULU GHRITA IN ITS INDICATIONS- LITERARY REVIEW

2021 ◽  
Vol 9 (6) ◽  
pp. 1266-1273
Author(s):  
Shivananda B Karigar
Keyword(s):  
Palliative Treatment ◽  
Treatment Protocol ◽  
Ayurvedic Medicine ◽  
Systemic Diseases ◽  
Diseased Condition ◽  
Single Formula ◽  
Almost All

Sneha Kalpanas in Ayurvedic medicine are very effective and unique preparations. In classics, for single formula- tion many indications are stated. For same preparation, some of ingredients are altered in various Samhitas. For a single disease, exact same protocol of treatment cannot be followed. Because treatment protocol will be based on many factors, treatment has to be employed by looking into the involvement of Dosha, Dooshya (tissues) and based on the diseased condition of a patient. In such condition, Yukti (reasoning capacity) of a physician plays important role. Panchatikta Guggulu Ghrita (PTG Ghrita) is one unique formulation which has many indications stated in different Ayurvedic classics. The utility of this medicine can be made by looking into classics thoroughly and analyzing the condition of a patient. PTG Ghrita is indicated in almost all Dhatu and all Srotogata vyadhis (Systemic diseases). PTG Ghrita can be used as Sneha Drava, as a Shodhanaga sneha (oleation in purificatory therapies), as a Shamananga sneha (oleation in Palliative treatment) and also it can be used as Sneha Dravya in Basti dravya (drugs in Enema therapy). Keywords: PTG Ghrita, Panchatikta Guggulu Ghrita, Panchatikta Ghrita Guggulu, Asti-MajjagataVataVikara,

scholarly journals A Clinical Study to Evaluate the Efficacy of Asthapana Basti and Uttar Basti in Asrigdara w.s.r to Abnormal Uterine Bleeding

AYUSHDHARA ◽  
2021 ◽  
pp. 3482-3489
Author(s):  
Kaminey ◽  
Soni Kapil ◽  
Anil Bhardawaj
Keyword(s):  
Clinical Study ◽  
Hormonal Therapy ◽  
Abnormal Uterine Bleeding ◽  
Signs And Symptoms ◽  
Good Health ◽  
Uterine Bleeding ◽  
Total Effect ◽  
Inclusion Criteria ◽  
Group I ◽  
Effect Of Therapy

Regular periods are necessary to maintain good health of women. Any abnormality in Rituchakra leads to excessive and irregular uterine bleeding which is known as Asrigdara which can be correlated to Abnormal Uterine bleeding. In Ayurvedic text, many preparations are described to treat Asrigdara. Samshodhan therapy is mainstay in the management of Artava related disorders of which Basti is supreme to manage Asrigdara. In conventional science, Hormonal therapy is given but chances of recurrence of the disease are high. This study was planned to provide simple, safe, non- hormonal drug for the patients of Asrigdara. Total 40 patients fulfilling the inclusion criteria were selected randomly from Dept. of Stree roga and Prasuti tantra O.P.D.and I.P.D. The total effect of drug was evaluated on the basis of signs and symptoms after completion of therapy. Overall effect of therapy shows in group-I 6 (60%) patients were markedly improved, 11 (61.11%) were partially improved and 1 (5.6%) was not improved and group II- 6 (33.33%) patients were cured, 9 (50%) were markedly improved, 2 (11.1%) were partially improved, and 1 (5.6%) was unimproved. Thus, Basti Chikitsa manifested promising results for the management of Asrigdara, although hormonal pill manifested better cycle but for shorter duration.

scholarly journals EFFICACY OF KSHARASOOTRA LIGATION IN ARSHACHIKITSA W.S.R. TO THIRD DEGREE HAEMORRHOIDS

AYUSHDHARA ◽  
2020 ◽  
pp. 2875-2881
Author(s):  
Verma Shweta
Keyword(s):  
Food Habits ◽  
Sedentary Lifestyle ◽  
Total Effect ◽  
Complete Relief ◽  
Vast Number ◽  
Significance Level ◽  
Prolonged Sitting ◽  
Effect Of Therapy ◽  
Anorectal Region

Enumeration of the vast number of aetiological factors (including dietetic ingredients, habits of prolonged sitting during defaecation etc.) and the systematic description of pathogenesis are indicative of scientific knowledge of the disease haemorrhoid. Its incidence has increased due to Mithyaahara- Vihara (faulty food habits and improper sedentary lifestyle). In third degree haemorrhoid pile masses prolapses during defaecation and need to be replaced manually. Ksharasootra ligation is mentioned in treatment of Arshachikitsa. In present study efficacy of Ksharasootra ligation in Arshachikitsa w.s.r. to third degree haemorrhoids Ksharasootra has been prepared using the methodology based on the description in the Ayurvedic text of 17th centaury Rasakamadhenu with some necessary modifications. Ksharasootra Ligation was done in randomly selected 15 patients of either sex with third degree haemorrhoids. The study design was open, randomized, and prospective. The duration of the trial was of 15 days, with a follow-up of 4 weeks. The total effect of therapy was assessed based on Clinical & Postoperative criteria. Statistical analysis has determined significance of the treatment. For all values significance level was p<0.05. In proctorrhagia percentage relief was 81% and results were highly significant while in prolapse percentage relief was 95%. Ksharasootra ligation had statistically highly significant and better results after treatment (p<0.001). Percentage relief in discharge per anum was 66.6% (p<0.05) and percentage relief in heaviness in the anorectal region was 80.63% with highly significant results in both complaints. According to the total effect of therapy 93.3% patients were cured while 6.6% patients were markedly improved after Ksharasootra ligation. Prolapse & Proctorrhagia (Chief clinical complaints of haemorrhoids) were almost completely cured after Ksharsootra ligation. Ksharasootra ligation results in higher degree of patient satisfaction in third-degree haemorrhoid patients. It can be concluded that Ksharasootra ligation gives almost complete relief from the symptoms of haemorrhoid.

Habitat Association of Klebsiella Species

1985 ◽  
Vol 6 (2) ◽  
pp. 52-58 ◽  
Author(s):  
Susan T. Bagley
Keyword(s):  
Drinking Water ◽  
Gastrointestinal Tract ◽  
Surface Waters ◽  
Industrial Effluents ◽  
Opportunistic Pathogen ◽  
Habitat Associations ◽  
Habitat Association ◽  
Klebsiella Species ◽  
Almost All ◽  
Polluted Waters

AbstractThe genus Klebsiella is seemingly ubiquitous in terms of its habitat associations. Klebsiella is a common opportunistic pathogen for humans and other animals, as well as being resident or transient flora (particularly in the gastrointestinal tract). Other habitats include sewage, drinking water, soils, surface waters, industrial effluents, and vegetation. Until recently, almost all these Klebsiella have been identified as one species, ie, K. pneumoniae. However, phenotypic and genotypic studies have shown that “K. pneumoniae” actually consists of at least four species, all with distinct characteristics and habitats. General habitat associations of Klebsiella species are as follows: K. pneumoniae—humans, animals, sewage, and polluted waters and soils; K. oxytoca—frequent association with most habitats; K. terrigena— unpolluted surface waters and soils, drinking water, and vegetation; K. planticola—sewage, polluted surface waters, soils, and vegetation; and K. ozaenae/K. rhinoscleromatis—infrequently detected (primarily with humans).

SEM Cold Stage Techniques for the Observation of Vegetative and Floral Apices of Oat (Avena sativa L.) Plants

1977 ◽  
Vol 35 ◽  
pp. 590-591
Author(s):  
B. K. Kirchoff ◽  
L.F. Allard ◽  
W.C. Bigelow
Keyword(s):  
Critical Point ◽  
Avena Sativa ◽  
Substantial Improvement ◽  
Fresh Tissue ◽  
Cold Stage ◽  
Critical Point Drying ◽  
Almost All ◽  
Cell Collapse ◽  
Conductive Paint ◽  
Carbon Based

In attempting to use the SEM to investigate the transition from the vegetative to the floral state in oat (Avena sativa L.) it was discovered that the procedures of fixation and critical point drying (CPD), and fresh tissue examination of the specimens gave unsatisfactory results. In most cases, by using these techniques, cells of the tissue were collapsed or otherwise visibly distorted. Figure 1 shows the results of fixation with 4.5% formaldehyde-gluteraldehyde followed by CPD. Almost all cellular detail has been obscured by the resulting shrinkage distortions. The larger cracks seen on the left of the picture may be due to dissection damage, rather than CPD. The results of observation of fresh tissue are seen in Fig. 2. Although there is a substantial improvement over CPD, some cell collapse still occurs.Due to these difficulties, it was decided to experiment with cold stage techniques. The specimens to be observed were dissected out and attached to the sample stub using a carbon based conductive paint in acetone.

Electron microscopy studies of plasma-sprayed materials

1983 ◽  
Vol 41 ◽  
pp. 70-71
Author(s):  
K.R. Subramanian ◽  
A.H. King ◽  
H. Herman
Keyword(s):  
Plasma Spraying ◽  
Substrate Surface ◽  
Flame Temperature ◽  
Ceramic Coatings ◽  
Metallic Substrates ◽  
Hot Plasma ◽  
Almost All ◽  
Plasma Sprayed ◽  
Hostile Environments ◽  
Plasma Spraying Process

Plasma spraying is a technique which is used to apply coatings to metallic substrates for a variety of purposes, including hardfacing, corrosion resistance and thermal barrier applications. Almost all of the applications of this somewhat esoteric fabrication technique involve materials in hostile environments and the integrity of the coatings is of paramount importance: the effects of process variables on such properties as adhesive strength, cohesive strength and hardness of the substrate/coating system, however, are poorly understood.Briefly, the plasma spraying process involves forming a hot plasma jet with a maximum flame temperature of approximately 20,000K and a gas velocity of about 40m/s. Into this jet the coating material is injected, in powder form, so it is heated and projected at the substrate surface. Relatively thick metallic or ceramic coatings may be speedily built up using this technique.

Vacuum System to Minimize the Specimen Contamination of High-Performance EM

1977 ◽  
Vol 35 ◽  
pp. 68-69
Author(s):  
N. Yoshimura ◽  
K. Shirota ◽  
T. Etoh
Keyword(s):  
Electron Microscope ◽  
High Speed ◽  
High Performance ◽  
High Vacuum ◽  
Vacuum System ◽  
Pump System ◽  
Pumping System ◽  
Diffusion Pump ◽  
Almost All ◽  
Cascade Type

One of the most important requirements for a high-performance EM, especially an analytical EM using a fine beam probe, is to prevent specimen contamination by providing a clean high vacuum in the vicinity of the specimen. However, in almost all commercial EMs, the pressure in the vicinity of the specimen under observation is usually more than ten times higher than the pressure measured at the punping line. The EM column inevitably requires the use of greased Viton O-rings for fine movement, and specimens and films need to be exchanged frequently and several attachments may also be exchanged. For these reasons, a high speed pumping system, as well as a clean vacuum system, is now required. A newly developed electron microscope, the JEM-100CX features clean high vacuum in the vicinity of the specimen, realized by the use of a CASCADE type diffusion pump system which has been essentially improved over its predeces- sorD employed on the JEM-100C.

Quantitative Freeze Fracture Studies of Gap Junctions in Somatic Cell Hybrids, Their Parents, and Revertants

1976 ◽  
Vol 34 ◽  
pp. 218-219
Author(s):  
W. J. Larsen ◽  
R. Azarnia ◽  
W. R. Loewenstein
Keyword(s):  
Gap Junctions ◽  
Striated Muscle ◽  
Freeze Fracture ◽  
Cell Movement ◽  
Dye Molecules ◽  
Somatic Cell Hybrids ◽  
Cell Coupling ◽  
Normal Cells ◽  
Mediate Cell ◽  
Almost All

Although the physiological significance of the gap junction remains unspecified, these membrane specializations are now recognized as common to almost all normal cells (excluding adult striated muscle and some nerve cells) and are found in organisms ranging from the coelenterates to man. Since it appears likely that these structures mediate the cell-to-cell movement of ions and small dye molecules in some electrical tissues, we undertook this study with the objective of determining whether gap junctions in inexcitable tissues also mediate cell-to-cell coupling.To test this hypothesis, a coupling, human Lesh-Nyhan (LN) cell was fused with a non-coupling, mouse cl-1D cell, and the hybrids, revertants, and parental cells were analysed for coupling with respect both to ions and fluorescein and for membrane junctions with the freeze fracture technique.

Analytical Electron Microscopy Study of Second-Phase Particles in 7075 and 7475 Aluminum Alloys

1985 ◽  
Vol 43 ◽  
pp. 348-349
Author(s):  
M. Raghavan ◽  
J. Y. Koo ◽  
J. W. Steeds ◽  
B. K. Park
Keyword(s):  
Aluminum Alloys ◽  
Silicon Oxide ◽  
Analytical Electron Microscopy ◽  
Microscopy Study ◽  
Electron Microscopy Study ◽  
Partial Substitution ◽  
Second Phase ◽  
X Ray ◽  
Second Phase Particles ◽  
Almost All

X-ray microanalysis and Convergent Beam Electron Diffraction (CBD) studies were conducted to characterize the second phase particles in two commercial aluminum alloys -- 7075 and 7475. The second phase particles studied were large (approximately 2-5μm) constituent phases and relatively fine ( ∼ 0.05-1μn) dispersoid particles, Figures 1A and B. Based on the crystal structure and chemical composition analyses, the constituent phases found in these alloys were identified to be Al7Cu2Fe, (Al,Cu)6(Fe,Cu), α-Al12Fe3Si, Mg2Si, amorphous silicon oxide and the modified 6Fe compounds, in decreasing order of abundance. The results of quantitative X-ray microanalysis of all the constituent phases are listed in Table I. The data show that, in almost all the phases, partial substitution of alloying elements occurred resulting in small deviations from the published stoichiometric compositions of the binary and ternary compounds.

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