scholarly journals A Study on Acne Improvement Effect of Fermented Rhus verniciflua Stokes and Orostachys japonicus A. Berger Complex Extract Cosmetics

2021 ◽  
Vol 27 (4) ◽  
pp. 1021-1027
Author(s):  
Seo-Young Park ◽  
Young-Jin So
Keyword(s):  
Clinical Trial ◽  
Control Group ◽  
Rhus Verniciflua Stokes ◽  
Rhus Verniciflua ◽  
Improvement Effect ◽  
Experimental Group

In this study, a clinical trial was conducted to confirm the effectiveness of cosmetics containing Fermented <i>Rhus verniciflua</i> Stokes · <i>Orostachys japonicus</i> A. Berger Complex Extract (FRO) on acne skin improvement. The result is as follows: After 6 weeks of using FRO cosmetics, it was confirmed that acne comedones, papules, and pustules were significantly reduced. In addition, as a result of analyzing the change in acne status with the KAGS grade, the experimental group improved from M = 2.07 before the experiment to M = 1 after 6 weeks. In addition, the results of acne improvement satisfaction were statistically significant at the 2nd week (p<.01), 4th week (p<.04), and 6th week (p<.01) between the experimental group and the control group. In addition, as a result of analyzing the acne improvement effect of experts, it was statistically significant at the 2nd week (p<.001), 4<sup>th</sup> week (p<.001), and 6th week (p<.001) between the experimental group and the control group. Therefore, It was confirmed that Fermented <i>Rhus verniciflua</i> Stokes · <i>Orostachys japonicus</i> A. Berger complex extract (FRO) can be useful as a functional cosmetic because it has the effect of improving acne skin.

scholarly journals A Study on Acne Improvement Effect of Fermented Rhus verniciflua Stokes and Orostachys japonicus A. Berger Complex Extract Cosmetics

2021 ◽  
Vol 27 (4) ◽  
pp. 1021-1027
Author(s):  
Seo-Young Park ◽  
Young-Jin So
Keyword(s):  
Clinical Trial ◽  
Control Group ◽  
Rhus Verniciflua Stokes ◽  
Rhus Verniciflua ◽  
Improvement Effect ◽  
Experimental Group

In this study, a clinical trial was conducted to confirm the effectiveness of cosmetics containing Fermented Rhus verniciflua Stokes · Orostachys japonicus A. Berger Complex Extract (FRO) on acne skin improvement. The result is as follows: After 6 weeks of using FRO cosmetics, it was confirmed that acne comedones, papules, and pustules were significantly reduced. In addition, as a result of analyzing the change in acne status with the KAGS grade, the experimental group improved from M = 2.07 before the experiment to M = 1 after 6 weeks. In addition, the results of acne improvement satisfaction were statistically significant at the 2nd week (p<.01), 4th week (p<.04), and 6th week (p<.01) between the experimental group and the control group. In addition, as a result of analyzing the acne improvement effect of experts, it was statistically significant at the 2nd week (p<.001), 4th week (p<.001), and 6th week (p<.001) between the experimental group and the control group. Therefore, It was confirmed that Fermented Rhus verniciflua Stokes · Orostachys japonicus A. Berger complex extract (FRO) can be useful as a functional cosmetic because it has the effect of improving acne skin.

scholarly journals Effects of a positive thinking program on hope and sleep quality in Iranian patients with thalassemia: a randomized clinical trial

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Somayeh Makaremnia ◽  
Marieh Dehghan Manshadi ◽  
Zahra Khademian
Keyword(s):  
Clinical Trial ◽  
Sleep Quality ◽  
Training Program ◽  
Randomized Clinical Trial ◽  
Thalassemia Major ◽  
Trial Registration ◽  
Control Group ◽  
Positive Thinking ◽  
Experimental Group

Abstract Background Thalassemia have a negative impact on the patients' psychological health and sleep quality. This study aimed to determine the effects of a positive thinking training program on hope and sleep quality of patients with thalassemia major. Methods This randomized clinical trial was conducted on 78 patients with thalassemia major including 36 males (46.2%) and 42 females (53.8%) with a mean age of 25.56 ± 29.6 in Iran. Subjects were randomly assigned into experimental and control groups. Experimental group received 16 h training based on positive thinking materials published by Martin Seligman. Control group received only usual programs. Data were collected at baseline, as well as immediately and one month after the intervention, using Snyder’s Hope Scale and the Pittsburgh Sleep Quality Index. Data analysis was performed using SPSS Software 18.0; statistical tests included the independent T-test, the Chi-square, Mann Whitney, and Friedman test. Significance level was set at 0.05 in this study. Results The experimental group had a significantly higher mean hope score compared to the control group immediately (45.38 ± 7.82 vs. 35.32 ± 5.54, P < 0.001) and one month following intervention (44.67 ± 3.47 vs. 35 ± .54, P < 0.001). Moreover, the mean sleep quality scores of the experimental group was significantly greater than that for control group immediately (5.35 ± 2.02 vs. 7 ± 2.4, P = 0.004) and one month after the intervention (4.23 ± 2.2 vs.7.02 ± 3.03, P < 0.001). Conclusion Since our training program on positive thinking improved hope and quality of sleep in patients with thalassemia major, we recommend the use of such courses as an important step toward promotion of hope and sleep quality among these patients. Trial registration The name of the registry: Iranian Registry of Clinical Trials. Trial Registration Number: IRCT2017010431774N1. URL of the trial registry record: https://en.irct.ir/trial/24923. Registration Date: 07/03/2017.

scholarly journals Stress of nursing students in clinical simulation: a randomized clinical trial

2018 ◽  
Vol 71 (3) ◽  
pp. 967-974 ◽  
Author(s):  
Radamés Boostel ◽  
Jorge Vinícius Cestari Felix ◽  
Carina Bortolato-Major ◽  
Edivane Pedrolo ◽  
Stela Adami Vayego ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Nursing Students ◽  
Randomized Clinical Trial ◽  
Interpersonal Relationships ◽  
Control Group ◽  
High Fidelity ◽  
Clinical Simulation ◽  
Skill Laboratory ◽  
Before And After ◽  
Experimental Group

ABSTRACT Objective: To evaluate and compare the perception of stressors by nursing students before and after a high-fidelity clinical simulation or conventional laboratory practice class. Method: This is a randomized clinical trial conducted with 52 nursing students. Both groups had theoretical classes about cardiothoracic physical examination, followed by practice class in skill laboratory. In addition, the experimental group took part in a high-fidelity simulation scenario. Stressors were evaluated before and after class, with the application of KEZKAK questionnaire. Results: The experimental group was significantly more worried about six factors related to lack of competence and to interpersonal relationships (p < 0.05), while the control group was significantly more worried about being in contact with suffering (p = 0.0315). Conclusion: The simulation affects students’ perception of stressors and promotes their self-evaluation and critical thinking regarding the responsibility that comes with their learning.

A Controlled Clinical Trial of Local Anesthesia for Lumbar Punctures in Newborns

PEDIATRICS ◽  
1991 ◽  
Vol 88 (4) ◽  
pp. 663-669 ◽  
Author(s):  
Fran L. Porter ◽  
J. Philip Miller ◽  
F. Sessions Cole ◽  
Richard E. Marshall
Keyword(s):  
Carbon Dioxide ◽  
Clinical Trial ◽  
Heart Rate ◽  
Lumbar Puncture ◽  
Local Anesthesia ◽  
Subcutaneous Administration ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Transcutaneous Oxygen ◽  
Experimental Group

To evaluate the efficacy of subcutaneous administration of lidocaine for reducing physiologic instability in acutely ill newborns during clinically required procedures, 81 neonates who required lumbar punctures within the first month of life were stratified by birth weight and respiratory support and randomly assigned to an experimental or a control group. The experimental group received an injection of 0.1 mL/kg of 1% lidocaine prior to the lumbar puncture. The control group received a nonanesthetized lumbar puncture without placebo. Changes in heart rate, respiratory rate, transcutaneous oxygen and carbon dioxide tensions, and heart rate variability from baseline, preparatory (positioning/handling), lumbar puncture, and recovery periods were measured. The administration of lidocaine did not minimize physiologic instability in response to the lumbar puncture nor was it associated with any detectable adverse effects other than prolonging the duration of the lumbar puncture. Although significant physiologic changes were observed in response to preparatory procedures, few additional changes beyond those occurred in response to lumbar punctures in either the experimental or control group. It is concluded that local anesthesia failed to influence manifestations of physiologic instability during neonatal lumbar punctures and that preparatory procedures were more destabilizing than either the administration of lidocaine or the lumbar puncture itself. The results suggest that the management of newborns requires emphasis on minimizing the destabilizing effects of required and frequent handling procedures.

scholarly journals Efficacy and Safety of Socheongryong-Tang Among Atopic Dermatitis Patients With Respiratory Disorders: A Double-Blinded, Randomized, Placebo-Controlled Clinical Trial

2020 ◽  
Vol 11 ◽  
Author(s):  
Ju Hyun Lee ◽  
Eun Heui Jo ◽  
Jee Youn Jung ◽  
Young-Eun Kim ◽  
Mi-Ju Son ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Atopic Dermatitis ◽  
Safety Evaluation ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Efficacy And Safety ◽  
Inflammatory Skin Disease ◽  
Double Blinded ◽  
Study Participants ◽  
Experimental Group

Atopic dermatitis is a chronic inflammatory skin disease that affects the growth and development of children. The prevalence of atopic dermatitis has been continually increasing, and this has also been accompanied by rising socioeconomic costs. Interest has been growing in alternative medicine as a means of alleviating the burden of atopic dermatitis. This was a single-center, double-blinded, randomized, placebo-controlled investigator-led clinical trial including 60 atopic dermatitis patients. The participants were classified into an experimental group (30 persons) and a control group (30 persons), who were administered, respectively, socheongryong-tang or a placebo for 4 weeks. After 4 weeks of treatment, the participants visited the trial center again and assess their efficacy and safety. The researchers performed statistical comparisons of the changes in the SCORAD Index, amount and frequency of ointment use, and height and weight to assess the efficacy. To assess the safety, diagnostic tests and vital sign checks were performed at each visit, and the presence or absence of adverse events was observed. As a result, the frequency and the amount of steroid ointment application in both groups increased, but the experimental group showed less tendency (p = 0.081). Results of analyzing the children in the experimental group in relation to growth showed a significantly greater height growth than the control group (p &lt; 0.05). In addition, all study participants did not show any remarkable abnormal signs in the safety evaluation. In conclusion, compared to the control group, the experimental group, who took socheongryong-tang showed a tendency to be less dependent on steroid ointment and statistically significant increase in height.

scholarly journals Evaluation of the telephone intervention in the promotion of diabetes self-care: a randomized clinical trial

2016 ◽  
Vol 24 (0) ◽  
Author(s):  
Bárbara Sgarbi Morgan Fernandes ◽  
Ilka Afonso Reis ◽  
Heloisa de Carvalho Torres
Keyword(s):  
Physical Activity ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Self Care ◽  
The Self ◽  
Control Group ◽  
Telephone Intervention ◽  
Belo Horizonte ◽  
Clinical Trials Registry ◽  
Experimental Group

ABSTRACT Objective: to evaluate the effectiveness of the telephone intervention for promoting self-care related to physical activity and following a diet plan in users with diabetes, compared to conventional monitoring of users over a six-month period. Method: this was a randomized clinical trial, which included 210 users with diabetes, linked to eight Primary Health Units of Belo Horizonte, Minas Gerais. The experimental group (104 members) received six telephone interventions over the six-month monitoring; the control group (106 members) received conventional monitoring. To evaluate the self-care practices related to physical activity and following a healthy eating plan, in both groups, the self-care questionnaire was applied before the intervention and at three and six months after its start. Results: the mean effect of self-care scores in the experimental group was 1.03 to 1.78 higher than the control group, with progressive and significant improvement (p<0.001). Conclusion: the results indicate that the telephone intervention had a beneficial effect on diabetes self-care. The primary identifier of the clinical trials registry was: RBR-8wx7qb.

Marital Problems and Treatment Outcome in Depressed Women

1987 ◽  
Vol 151 (5) ◽  
pp. 652-659 ◽  
Author(s):  
Roslyn H. Corney
Keyword(s):  
Clinical Trial ◽  
Social Work ◽  
Social Workers ◽  
Control Group ◽  
Women Patients ◽  
Marital Problems ◽  
Routine Treatment ◽  
Work Intervention ◽  
Experimental Group

In a clinical trial investigating the effectiveness of social work intervention with depressed women patients in general practice, 80 women were randomly allocated to an experimental group for referral to attached social workers or to a control group for routine treatment by their GPs. They were reassessed at 6 and 12 months. The results indicated that women who had major marital problems were more likely to be depressed at follow-up than those with good relationships. However, patients with marital difficulties in the experimental group made more improvement than the controls. Women initially assessed as suffering from ‘acute on chronic’ depression and having major marital difficulties were found to benefit most from social work intervention.

scholarly journals Pillow positioning facilitates independent bridging for bedpan use in pelvic fractures

1992 ◽  
Vol 48 (3) ◽  
pp. 41-44 ◽  
Author(s):  
Jeanette A. Fourie ◽  
Eileen M.P. Lief ◽  
Timothy T. Dunne
Keyword(s):  
Clinical Trial ◽  
Stainless Steel ◽  
Pelvic Fractures ◽  
Control Group ◽  
Mechanical Advantage ◽  
Block Randomisation ◽  
Significant Difference ◽  
Experimental Group ◽  
Conventional Stainless Steel

The idea of giving a patient with fractures of the pelvis a mechanical advantage, by placing pillows under his/her back in order to make bridging for the bedpan easier, was tested in this clinical trial. Twenty nine subjects were entered by block randomisation into the experimental group and twenty nine into the control group. The number of days from entry into the trial until independent bridging was noted. Independent bridging is defined as the patient being able to lift high enough to slide a conventional stainless steel bedpan under the buttocks. Results show that there is a significant difference in time to bridging (Y = 0,602, p = 0,0027) in favour of the experimental group. Other variables studied appear to marginally favour the control rather than the experimental group, thus suggesting that the pillow method could be used safely and effectively in the treatment of patients who have sustained a range of pelvic fractures.

scholarly journals Effects of exercise combined with whole body vibration in patients with patellofemoral pain syndrome: a randomised-controlled clinical trial

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Angel Yañez-Álvarez ◽  
Beatriz Bermúdez-Pulgarín ◽  
Sergio Hernández-Sánchez ◽  
Manuel Albornoz-Cabello
Keyword(s):  
Clinical Trial ◽  
Lower Limb ◽  
Repeated Measures ◽  
Whole Body Vibration ◽  
Patellofemoral Pain ◽  
Whole Body ◽  
Control Group ◽  
Body Vibration ◽  
And Function ◽  
Experimental Group

Abstract Background Patellofemoral pain is a prevalent condition in the general population, especially in women, and produces functional impairment in patients. Therapeutic exercise is considered an essential part of the conservative management. The use of vibration platforms may help improve strength and function and reduce pain in patients with knee disorders. The aim of this investigation was to determine the effects of adding whole body vibration (vertical, vibration frequency of 40 Hz, with an amplitude from 2 to 4 mm) to an exercise protocol for pain and disability in adults with patellofemoral pain. Methods A randomised clinical trial was designed, where 50 subjects were randomly distributed into either an exercise group plus whole body vibration or a control group. Pain, knee function (self-reported questionnaire) and range of motion and lower limb functionality were assessed at baseline and at 4 weeks. The experimental group performed 12 supervised sessions of hip, knee and core strengthening exercises on a vibration platform 3 times per week during 4 weeks. The control group followed the same protocol but without vibration stimuli. Differences in outcome measures were explored using an analysis of the variance of 2 repeated measures. Effect sizes were estimated using Square Eta (η2). Significant level was set al P < 0.05. Results Statistically significant differences were found after intervention in favour of the experimental group in the between-groups comparison and in the interaction of the experimental group before and after treatment in terms of pain perception (P = 0.000; η2 = 0.63) and function outcomes scores (P = 0.000; η2 0.39 and 0.51 for lower limb functional scale and Kujala scores respectively). Conclusion A 4-week whole body vibration exercise programme reduces pain level intensity and improves lower limb functionality in patellofemoral pain patients and is more effective than exercise alone in improving pain and function in the short-term. Trial registration ClinicalTrials.gov (NCT04031248). This study was prospectively registered on the 24th July, 2019.

scholarly journals Music listening for anxiety relief in children in the preoperative period: a randomized clinical trial

2016 ◽  
Vol 24 (0) ◽  
Author(s):  
Mariana André Honorato Franzoi ◽  
Cristina Bretas Goulart ◽  
Elizabete Oliveira Lara ◽  
Gisele Martins
Keyword(s):  
Clinical Trial ◽  
Elective Surgery ◽  
Nursing Intervention ◽  
Preoperative Anxiety ◽  
Control Group ◽  
Music Listening ◽  
Preoperative Period ◽  
Significant Difference ◽  
Anxiety Levels ◽  
Experimental Group

ABSTRACT Objective: to investigate the effects of music listening, for 15 minutes, on the preoperative anxiety levels in children undergoing elective surgery in comparison with conventional pediatric surgical care. Method: randomized controlled clinical trial pilot study with 52 children in the preoperative period, aged 3 to 12 years, undergoing elective surgery and randomly allocated in the experimental group (n = 26) and control group (n = 26). Anxiety was assessed in both groups by the application of the modified Yale Preoperative Anxiety Scale and measurement of the physiological variables, upon arrival and 15 minutes after the first measurement. Results: there was a statistically significant difference in preoperative anxiety between the two groups only in relation to the physiological variable, since the respiratory rate of preschool children in the experimental group reduced in the second measurement compared to the control group (p = 0.0453). The experimental group showed a statistically significant reduction in anxiety levels after 15 minutes of music listening (p = 0.0441), specifically with regard to the behavioral domains of activity, vocalization, emotional expression and apparent awakening state. Conclusion: music listening emerges as a potential nursing intervention for relief of preoperative anxiety in children undergoing surgical procedures. RBR-7mcr59.

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