Effect of Immunonutrition supplementation on Post-operative outcome after major Gastrointestinal surgery for Malignancy

2021 ◽  
pp. 2258-2261
Author(s):  
Saraswathy Sivaprasadan ◽  
Anju Kochupurackal Paul ◽  
Sudhindran Surendran ◽  
Uma Devi Padma
Keyword(s):  
Hospital Stay ◽  
Gastrointestinal Surgery ◽  
Caloric Intake ◽  
The Body ◽  
Calorie Intake ◽  
Omega 3 ◽  
Entire Study ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

This prospective, pilot study evaluated the effect of immunonutrition supplementation using Pentasure Immunomax® on recovery after major gastrointestinal (GI) surgery for malignancy. It included two groups of patients (n = 25 each) who underwent major GI surgery for malignancy in two units, one of which routinely gave Pentasure Immunomax® (L – arginine, omega 3 fatty acids and ribonucleic acids) for two weeks following surgery (Group 1) while the other did not (Group 2). The pre-operative nutritional status of the patients were assessed using Subjective Global Assessment (SGA) scale. Post-operatively the following parameters were compared between the two groups: complications (using Clavien Dindo scale), calorie intake, length of intensive care unit (ICU) and hospital stay using SPSS software, version 20.0. Based on the SGA score, 66% of the entire study population was moderately malnourished, while 6% were severely malnourished. On assessing the body mass index, 26 (52%) patients were found to be overweight or obese, out of which 16 patients were found to be moderately malnourished. The mean caloric intake in Group 1 was significantly more than in Group 2 (1112.7± 51.6 versus 874.8±56.7; p = 0.0032). There was, however, no significant difference between the two groups in complications, ICU or hospital stay. The incidence of malnutrition in patients undergoing major GI surgery for malignancy is high even amongst those who are overweight/obese. Use of immunonutrition may help in better attainment of adequate calorie in post-operative period.

scholarly journals Miniplate 1.5 fixation for the repair of mandibular osteotomies in cats

2011 ◽  
Vol 26 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Adelina Maria da Silva ◽  
Wilson Machado de Souza ◽  
Patrícia de Athayde Barnabé ◽  
Marion Burkhardt de Koivisto ◽  
Nair Trevizan Machado de Souza
Keyword(s):  
Radiolucent Line ◽  
The Body ◽  
Bone Union ◽  
Dental Occlusion ◽  
Mandibular Fractures ◽  
Significant Difference ◽  
Osteotomy Line ◽  
Group 2 ◽  
Adult Cats ◽  
Group 1

Purpose: To evaluate the application of the maxillofacial miniplate 1.5 in the repair of unilateral mandibular osteotomies in cats. Methods: Twelve adult cats were divided into two groups. In group 1 (n=6), the osteotomy was performed in the body of the mandible, behind the 1st molar. In group 2 (n=6), the osteotomy was performed between the 4th premolar and 1st molar. The osteotomy was fixed with a titanium miniplate 1.5. Oral alimentation was reinitiated 24 hours after surgery. Cats were euthanized at 12 weeks postoperative. Results: Radiographs taken 1 week after surgery showed a radiolucent line. The osteotomy line was not more visible on the radiographs taken at 12 weeks postoperative. Macroscopic examination confirmed alignment and bone union of operated hemimandibles. Histological examination showed formation of woven bone within the osteotomy line. The percentage of bone tissue at these areas was measured by the histometry. There was no statistically significant difference between the values of group 1(75.07 ± 5.99) and group 2 (74.76 ± 8.54) (Mann-Whitney's test p= 0.469). Conclusion: We concluded that the use of miniplate 1.5 for the fixation of mandibular osteotomy in cats provided the main goals in the treatment of mandibular fractures: bone union, normal dental occlusion and immediate return to oral alimentation.

Abstract WP380: Thyrotoxicosis is Associated With Worse In-Hospital Mortality in Patients With Ischemic Stroke

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Sakiru O Isa ◽  
Olajide Buhari ◽  
Hameem Changezi
Keyword(s):  
Ischemic Stroke ◽  
Hospital Mortality ◽  
Length Of Hospital Stay ◽  
The Body ◽  
Significant Difference ◽  
History Of ◽  
Group 3 ◽  
Group 2 ◽  
Time Of Presentation ◽  
Group 1

Introduction: Hyperthyroidism increases the basal metabolic rate and affects most systems in the body. Patients with hyperthyroidism have been shown to have a higher incidence of ischemic stroke. There is a paucity of information regarding its effects on the short-term outcomes of patients admitted with ischemic stroke. Hypothesis: Hyperthyroidism is associated with worse in-hospital outcomes in patients admitted for ischemic stroke. Methods: We queried the National Inpatient Sample to identify adult patients(aged 18 and above) admitted for ischemic stroke between January 2011 and December 2014. We compared those with a history of hyperthyroidism (group 1) and thyrotoxicosis on admission (group 2) with the rest of the patients (group 3). The main outcome was in-hospital mortality. Secondary outcomes included the length of hospital stay and cost of hospitalization. We used the logistic regression model and adjusted for baseline characteristics and co-morbidities. Results: There were 643,786 patients in the study, 0.44% had a history of hyperthyroidism, and 0.01% had thyrotoxicosis at the time of presentation. The odd of mortality in group 1 compared to group 3 was 0.89, 95% CI 0.75-1.05, p=0.16 while in group 2 compared to group 3, it was 2.42, 95% CI 1.29-4.52, p<0.006. The mean length of stay was also longer in group 2 with a mean difference of 8.06, 95% CI 4.74 - 11.39, p<0.0001. Conclusion: From the study, there was no significant difference in in-hospital mortality between patients with previously diagnosed hyperthyroidism and those without diagnosed hyperthyroidism. Patients who had thyrotoxicosis on admission, on the other hand, had worse outcomes compared to patients without thyrotoxicosis.

scholarly journals Miniplate fixation for the repair of segmental mandibular defects filled with autogenous bone in cats

2011 ◽  
Vol 26 (3) ◽  
pp. 174-180 ◽  
Author(s):  
Adelina Maria da Silva ◽  
Wilson Machado de Souza ◽  
Marion Burkhardt de Koivisto ◽  
Patrícia de Athayde Barnabé ◽  
Nair Trevizan Machado de Souza
Keyword(s):  
The Body ◽  
Bone Union ◽  
Dental Occlusion ◽  
Autogenous Bone ◽  
Iliac Crest Bone Graft ◽  
Mandibular Fractures ◽  
Segmental Defect ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

PURPOSE: To evaluate the use of maxillofacial miniplate 1.5 in the repair of segmental mandibular defects filled with autogenous bone in cats. METHODS: Twelve adult cats were divided into two groups. A segmental defect of 4mm was created in one of the hemimandibles and filled with autogenous iliac crest bone graft. The operated hemimandible was fixed with a 1.5mm titanium miniplate. In group 1 (n=6), the defect was performed in the body of the mandible, behind the 1st molar. In group 2 (n=6), the defect was performed between the 4nd premolar and 1st molar, with extraction of the 1st molar. Oral alimentation was reinitiated 24 hours after surgery. Cats were euthanized at 20 weeks postoperative. RESULTS: Incorporation of the graft was suggested by the radiographs taken 20 weeks after surgery. Macroscopic examination confirmed alignment and bone union of operated hemimandibles. Histological examination showed formation of woven bone in rostral and caudal mandible/graft interfaces. The percentage of bone tissue at these areas was measured by the histometry. There was no statistically significant difference between the values of group 1(64.48 ± 4.51) and group 2 (71.69 ± 14.47) (Mann-Whitney's test p= 0.294). CONCLUSION: The use of miniplate 1.5 for the fixation of mandibular defects filled with autogenous bone in cats provided the main goals in the treatment of mandibular fractures: bone union, normal dental occlusion and immediate return to oral alimentation.

scholarly journals Comparison of Complications from Radical Cystectomy between Old-Old versus Oldest-Old Patients

2014 ◽  
Vol 94 (1) ◽  
pp. 25-30 ◽  
Author(s):  
Evi Comploj ◽  
Jeremy West ◽  
Michael Mian ◽  
Luis Alex Kluth ◽  
Alexander Karl ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Radical Cystectomy ◽  
Medical Center ◽  
Oldest Old ◽  
Age Group ◽  
Cancer Specific Survival ◽  
Old Patients ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

Introduction: The purpose of this study was to evaluate and compare complications after radical cystectomy in patients aged ≥75 years. Materials and Methods: 251 patients aged 75-95 years (median 79) underwent radical cystectomy between 2000 and 2012 at four institutions. The patients were divided into two groups: ≥75-84 years of age (group 1) versus ≥85 years of age (group 2). Comorbidities, body mass index, and complications were obtained retrospectively, except at the Central Hospital of Bolzano and Weill Cornell Medical Center, which collected data prospectively. Cancer-specific survival, overall mortality, hospital stay, clinical outcome and complications were assessed. Complications were categorized using the Clavien-Dindo classification reporting system. The mean follow-up was 21 months. Results: The median hospital stay was 17 (2-91) days. Perioperative Clavien-Dindo grade ≥III complications were seen in 24.1% (48/199) of group 1 patients and 19.2% (10/52) of group 2 patients (p = 0.045). 30- and 90-day mortality was 4.5 and 13.5% in group 1 and 6.5 and 32.3% in group 2, respectively. Only the 90-day mortality rate was statistically significant (p < 0.05) between the two groups. The 3-year overall survival was 40% in group 1 and 34% in group 2. The 3-year cancer-specific survival was 52% in group 1 and 50% in group 2. Conclusions: We evaluated a large series of elderly (≥75 years) patients undergoing radical cystectomy at four institutions. Comparing patients aged ≥75-84 and ≥85 years revealed no significant difference in complications, 30-day mortality, overall and cancer-specific survival rates. Only 90-day mortality rates were significantly higher in the ≥85-year-old patients.

Independent and Interdependent Influence of Number of CD34+ Cells and Use of G-CSF on Outcomes in Autologous PBSCT Patients

Blood ◽  
2008 ◽  
Vol 112 (11) ◽  
pp. 4319-4319
Author(s):  
Meghana Trivedi ◽  
Sue Corringham ◽  
Sam Martinez ◽  
Katherine Medley ◽  
Edward D Ball
Keyword(s):  
Hospital Stay ◽  
Length Of Hospital Stay ◽  
Post Transplant ◽  
Cd34 Cells ◽  
Significant Difference ◽  
Autologous Pbsct ◽  
Group 3 ◽  
Group 2 ◽  
Neutrophil Engraftment ◽  
Group 1

Abstract Background: Recovery of neutrophilic granulocytes after autologous peripheral blood stem cell transplantation (PBSCT), and thus overall outcome, depends on 2 main factors: the quality and quantity of mobilized peripheral blood progenitor cell products (CD34+ cells) and the use of myeloid growth factors, such as granulocyte colony stimulating factor (G-CSF). Methods: We performed a 5-year (from February 2003 to January 2008) retrospective analysis of data to evaluate independent and interdependent influence of number of CD34+ cells and use of G-CSF on outcomes in autologous PBSCT patients. At the time of analysis, the practice at our institution was as follows: Autologous PBSCT patients receiving infusion of &lt; 5×106 CD34+ cells/kg were treated with daily subcutaneous injection of G-CSF (filgrastim 300 mg for &lt; 80 kg; 480 mg for ≥ 80 kg). In these patients, G-CSF was started on Day +5 and was continued until the ANC was &gt; 500/μl. On the other hand, autologous transplant patients who received ≥ 5×106 CD34+ cells/kg did not typically receive G-CSF. If engraftment did not occur after an “expected” length of time, G-CSF treatment was initiated at the discretion of the treating physician. The definition of “expected” length of time, however, varied from practitioner to practitioner. For the analysis, patients were divided in 3 groups: patients who collected &lt; 5×106 CD34+ cells/kg and received G-CSF (group 1, n=103), patients who were infused with ≥ 5×106 CD34+ cells/kg and did not receive G-CSF (group 2, n=155), and patients who received ≥ 5×106 CD34+ cells/kg and were given G-CSF (group 3, n=47). Time to neutrophil engraftment (ANC &gt;500/ml), time to platelet engraftment (platelets &gt; 20,000/ml), and post-transplant length of hospital stay were compared. Results: Median time to neutrophil engraftment was significantly shorter in patients who were treated with G-CSF (11 days) in groups 1 and 3, compared to those who were not (13 days) in group 2 (table 1). Similarly, median post-transplantation hospital stay was significantly longer in patients who did not receive G-CSF (14 days) in group 2 compared to patients who were treated with G-CSF (13 days) in groups 1 and 3. There was no significant difference in time to neutrophil engraftment and post-transplant hospital stay between groups 1 and 3, suggesting that these outcome parameters did not significantly depend on number of CD34+ cells infused in our patients if G-CSF was used. Median time to platelet engraftment was significantly longer in patients receiving &lt; 5×106 CD34+ cells/kg (12 days) in group 1 compared to patients infused with ≥ 5×106 CD34+ cells/kg (10 days) in groups 2 and 3. There was no significant difference in time to platelet engraftment between groups 2 and 3, indicating that G-CSF use did not influence platelet engraftment. Summary: These results suggest that a higher number of CD34+ cells helps accelerate platelet engraftment, but does not influence neutrophil engraftment and post-transplant length of hospital stay, as long as G-CSF treatment is instituted. The use of G-CSF accelerates neutrophil recovery, regardless of the number of CD34+ cells infused, without affecting platelet engraftment in patients undergoing autologous PBSCT. Based on this analysis, the practice at our institution has been revised to use G-CSF in all autologous transplant patients, regardless of the number of CD34+ cells, since this practice reduces the length of hospital stay. Table 1. A retrospective data analysis for patients treated at the UCSD BMT unit with autologous PBPCT from February 2003 to January 2008. The data is represented as a median value with a range indicated in parenthesis. * indicates significant difference from group 1, † indicates significant difference from group 2, and ‡ indicates significant difference from group 3 (p &lt; 0.001, Mann Whitney U test; Graph Pad Prism, version 3.02 (Graph Pad Software, San Diego, CA)). Abbreviations: ANC-absolute neutrophil count, LOS-length of hospital stay. Group 1 &lt; 5×106/kg (G) (N = 103) Group 2 ≥5×106/kg (no G) (N = 155) Group 3 ≥5×106/kg (G) (N = 47) CD34+ cells (×106/kg) 3.2 †,‡ (1.4–4.98) 6.8 * (5.0–16.7) 7.0 * (5.0–12.3) Initiation of G-CSF Day +5 N/A Day +5 (day 0–day +16) Time to ANC &gt; 500/ml (days) 11 † (9–28) 13 *,‡ (9–21) 11 † (8–17) Time to Platelet &gt; 20,000/ml (days) 12 †,‡ (6–42) 10 * (0–29) 10 * (0–27) Post-Transplant LOS (days) 13 † (10–38) 14 *,‡ (1–43) 13 † (10–18)

Pulmonary Excretion of Carbon Monoxide in the Human Infant as an Index of Bilirubin Production IV. Effects of Breast-feeding and Caloric Intake in the First Postnatal Week

PEDIATRICS ◽  
1980 ◽  
Vol 65 (6) ◽  
pp. 1170-1172 ◽  
Author(s):  
David K. Stevenson ◽  
Albert L. Bartoletti ◽  
Clinton R. Ostrander ◽  
John D. Johnson
Keyword(s):  
Carbon Monoxide ◽  
Caloric Intake ◽  
Human Infant ◽  
Significant Difference ◽  
Group 3 ◽  
The Mean ◽  
Group 2 ◽  
Breast Fed ◽  
Pulmonary Excretion ◽  
Group 1

Measurements of the pulmonary excretion rate of carbon monoxide (VEco) as an index of bilirubin production in the first several days of life were taken from 64 breast-fed or bottle-fed infants. Twenty-one infants (≥37 weeks of gestation) were breast-fed; 43 infants (28 to 42 weeks of gestation) were bottle-fed a commercially prepared formula. Information pertaining to their caloric intake during the 24-hour period preceding VECO determination was taken from 38 of the 43 infants who were bottle-fed and they were placed into three groups based on their caloric intake: (1) ≤60 kcal/kg/day (19 infants); (2) 61 to 100 kcal/kg/day (7 infants); and (3) &gt; 100 kcal/kg/day (12 infants). There was no significant difference in bilirubin production between bottle-fed and breast-fed infants. No effect of caloric deprivation on bilirubin production was demonstrated. The mean VECO values were 18.5 ± 0.9 (SE) for group 1, 17.7 ± 1.8 (SE) for group 2, and 16.2 ± 1.1 (SE) µl/kg/hr for group 3.

scholarly journals Combination of omega-3 polyunsaturated fatty acids and statins for the prevention of atrial fibrillation after coronary bypass surgery

2017 ◽  
Vol 95 (9) ◽  
pp. 817-823
Author(s):  
Olesya A. Rubanenko ◽  
O. V. Fatenkov ◽  
S. M. Khokhlunov ◽  
A. P. Semagin ◽  
D. V. Kuznetsov ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Leukocyte Count ◽  
Coronary Bypass ◽  
Omega 3 ◽  
Significant Difference ◽  
Before And After ◽  
The Difference ◽  
Group 2 ◽  
Group 1

Aim. To evaluate the influence of combination of omega-3 polyunsaturated fatty acids and atorvastatin on the risk of atrial fibrillation (AF) after coronary bypass surgery (CBS). Material and methods. The study included 114 patients divided into 2 groups, one comprised of 59 ones (75,6% men of mean age 62,0±7,3 yr given conventional medication), the other including 55 patients (80,0% men of mean age 59,4±6,7 yr given omega-3 polyunsaturated fatty acids 5 days before (2 g/d) and during 3 weeks after CBS (1 g/d)). All patients were treated with atorvastatin at the outpatient stage. IL-6,8, 10 and C-reactive protein (CRP), fibrinogen, troponin, NT-proBNP, superoxide dismutase (SOD), and myeloperoxidase were measured at admittance and on day 3.7±1.4 after surgery. Results. AF developed on day 5.9±4.9 (mean) after surgery. Patients of group 2 tended to have fewer new episodes of arrhythmia although no significant difference between the groups was documented (9,1% vs 18,6%, р=0,12). Group 2 included more smokers (74,5% vs 45,8%, р=0,002) and patients with atherosclerosis of lower limb arteries (87,3% vs 71,2%, р=0,03) but fewer those consuming nitrates (39,0% vs 18,2%, р=0,01) and Ca antagonists (45,8% vs 21,8%, р=0,006).Mean dose of atorvastatin given to patients of groups 1 and 2 was 24.7±12.5 and 25.1±10.5 mg/d respectively (р=0,2), duration of its intake 14.6±12.7 and 21.5±19.3 months (р<0,001). There. was no significant difference between leukocyte count, leukogram, IL-8, IL-10, NT-proBNP, and troponin levels before and after CBS. Surgical myocardial revascularization caused a rise in leukocyte count, shifted the leukogram toward predominance of stab and segmented cells, increased IL-8, IL-10, fibrinogen, NT-proBNP, CRP, and troponin levels in both groups. IL-8 and IL-10 levels remained normal before and after surgery. Preoperative IL-6 level in group 1 was significantly higher than in group 2 (21,7±13,0 vs 2.5±2,2 pg/ml, р<0,001). Postoperatively, the difference was absent. The CRP level before surgery was high in both groups (3122.7±2175.8 vs 3670.8±2490.0 U/g) but decreased after CBS although remained higher in group 1 (1957.6±1660.3 vs 1069.8±630.2 U/g, р<0,001). Myeloperoxidase level increased postoperatively in both groups but the difference was insignificant. Fibrinogen and CRP in the postoperative period increased more significantly in group 2 than in group 1 (4,9±1,4 vs 4,4±1,1 g/l, р=0,02 and 8,6±2,2 vs 5,4±2,3 mg/l respectively, р<0,001). Conclusion. The study revealed an insignificant decrease in the number of AF episodes in the early post-CDS period in patients treated with omega-3 polyunsaturated fatty acids and atorvastatin compared with those given the latter medication alone. Also, fibrinogen and CRP levels as markers of inflammation increased while SOD antioxidative activity decreased.

scholarly journals Impact of Anti-Toxoplasma gondii and adipose hormones with Insulin Resistant on obese aborted women

2020 ◽  
Vol 10 (01) ◽  
pp. 114-118
Author(s):  
Abeer J. Hassan ◽  
Nazar Sh. Mohammed ◽  
Muhannad Shweash ◽  
Hatem M. Hadeed
Keyword(s):  
Toxoplasma Gondii ◽  
Fasting Blood Glucose ◽  
Resistance Index ◽  
The Body ◽  
Control Group ◽  
Obese Women ◽  
Significant Difference ◽  
Patient Groups ◽  
Group 2 ◽  
Group 1

This study was carried out at Baghdad hospital in, for the period from November 2018 to July 2019. The study included (151) aborted obese women whose ages ranged between (18–41) years with positive Toxoplasma gondii infection. They were divided into two groups according to the body mass index (BMI) value: Group 1: consisted of 61 women with BMI less than 30, Group 2: consisted of (90) women with BMI greater than 30. The control group included (52) healthy volunteer women aged 19–41 years with negative Toxoplasma for comparison of the results. The case and controls were matched for age and gender. Serum samples were tested for fasting blood sugar, insulin, IgG, and IgM of Toxoplasma, Leptin, and Adiponectin as well as insulin resistance index. The results showed that the age factor was not significant between group 1 and group 2 when compared with the healthy group, and there was no significant change between group 2 comparing to group1. In this study, the result of BMI showed substantial increase in group 1, while highly marked increase in group 2 when both groups were compared with the control group. Finally, the levels of Toxoplasma IgG and IgM antibodies showed a highly significant increase in the two patient groups in comparison with the control group. An increase in mean value of leptin concentration was noticeable in group 1 and group 2 with a highly significant difference when compared with the control group. No significant difference was found in the levels of fasting blood glucose in Group 1 and Group 2 compared to the control group. Also, a significant difference in HOMA-IR and QUICK- IR was observed in the patient groups once associated control group. Data revealed a considerable difference with the glucose/insulin ratio in group 1, but a highly significant was noticed in group 2 when compared with the control group. HOMA-AD results showed a significant difference in Group 1 and a highly significant decrease in Group 2.

scholarly journals Endoscopic versus open harvesting of radial artery for CABG

2020 ◽  
Vol 28 (1) ◽  
Author(s):  
Mohamed Abdel Hafez Fouly
Keyword(s):  
Hospital Stay ◽  
Radial Artery ◽  
Artery Bypass ◽  
Open Technique ◽  
Short Term ◽  
Significant Difference ◽  
Safe Technique ◽  
Group 2 ◽  
Cabg Patients ◽  
Group 1

Abstract Background Endoscopic harvest of the radial artery avoids long forearm incisions and has better cosmesis compared to the open technique. The objective of this study was to compare the short-term results and wound-related complications of endoscopic radial artery harvest versus open technique. Results From 2013 to 2017, 800 patients had coronary artery bypass grafting; 88 patients of them had radial artery harvesting (11%). Two groups were included in the study according to the surgeon preference, endoscopic radial harvest (group 1, n = 30; 3.75% of total CABG patients) and open harvest (group 2, n = 58; 7.25% of total CABG patients). Group 1 had more males (25 (83.33%) vs. 35 (60.34%); p = 0.028). There was no difference in the preoperative comorbidities between both groups. The duration of the harvest was significantly longer in group 1 (median 40 min ranges from 38 to 42 min vs. 49 min ranges from 47 to 52 min in groups 1 and 2, respectively; p < 0.001). The operative time was longer in group 1 (median 302.5 min ranges from 295 to 310 min vs. 277 min ranges from 273 to 280 min in groups 1 and 2, respectively; p < 0.001). The hospital stay in the endoscopic radial artery harvest group was significantly shorter than that of open technique (median 7 days ranges from 6 to 7 days vs. 7.5 days ranges from 7 to 9 days; p < 0.001). There was no significant difference in the postoperative complications between both groups. One case (3.3%) was transformed from the endoscopic to open technique due to uncontrolled bleeding. Endoscopic technique was associated with more patients presenting with hand numbness (6 cases; 20% versus 3 cases 5.2%) and radial nerve injury (2 cases; 6.6% versus none), while open technique showed more cases of local hematoma (8 cases; 13.8% versus 1 case; 3.3%) and wound infection (6 cases; 10.34% versus none); p > 0.05. Conclusion Endoscopic radial artery harvest is associated with shorter harvest time and shorter hospital stay. Endoscopic radial artery harvest is a safe technique with good short-term outcomes. Longer follow-up is recommended.

Five-year survival after sigmoid resection and low vascular ligation versus left hemicolectomy and high ligation for stage I–III sigmoid carcinoma: a retrospective study

2014 ◽  
Vol 20 (4) ◽  
pp. 213-217
Author(s):  
Vytautas Vitkauskas ◽  
Narimantas Evaldas Samalavičius ◽  
Marija Vitkauskienė
Keyword(s):  
Hospital Stay ◽  
Sigmoid Resection ◽  
Stage I ◽  
High Ligation ◽  
Left Hemicolectomy ◽  
Significant Difference ◽  
Low Ligation ◽  
Group 2 ◽  
Group 1 ◽  
Sigmoid Cancer

Background. There is still a discussion whether or not high ligation of the inferior mesenteric artery and vein during surgery for sigmoid cancer has survival benefit compared to low ligation. Both operations are used today. The aim of our study was to evaluate retrospectively 5-year survival after low ligation in comparison with high ligation for stage I–III sigmoid cancer. Materials and methods. We reviewed 127 patients who were operated on for stage I–III sigmoid cancer during the period of 5 years (1 January 2003 – 31 December 2007) at the Oncology Institute of Vilnius University. Left hemicolectomy was performed in 20 cases (Group 1), whereas sigmoid resection was performed in 107 cases (Group  2). In Group  1 there were 10 men and 10 women, mean age was 66.4 (std. dev. 7.816, range 50–78). In Group 2 there were 46 men and 61 women, mean age was 66.71 (std. dev. 9.964, range 40–82). Results. Mean hospital stay was 15.8  days (std.  dev.  4.895, min.  10, max. 30) in Group 1 and 17.47 days (std. dev. 4.995, min. 7, max. 37) in Group 2 (p > 0.005). There were 2 postoperative complications in Group 1 (10%) and 27 in Group 2 (25.2%) (p > 0.005). 5-year survival in Group 1 was 70%, in Group 2 it was 72.9% (p > 0.005). Conclusions. In our study there was no significant difference in oper­ating time and other variables between the groups, but higher postoperative complication rate and a longer hospital stay was observed after sigmoid resection with low ligation in comparison with left hemicolectomy with high ligation. However, five-year survival rate was not different between the groups. In conclusion, our findings conclude that both techniques give adequate oncological results in cases of sigmoid cancer.

Sign in / Sign up

Export Citation Format

Share Document