scholarly journals COVID-19 morbimortality in long-term care facilities in the state of Bahia, Brazil

2021 ◽  
Vol 15 ◽  
Author(s):  
Meirelayne Borges Duarte ◽  
Isabela Lôbo Duarte ◽  
Lucas Maia Scardino Faria ◽  
Mônica Hupsel Frank ◽  
Helena Patáro de Oliveira Novaes ◽  
...  
Keyword(s):  
Ecological Study ◽  
Long Term Care ◽  
Global Analysis ◽  
Case Fatality ◽  
The State ◽  
Morbidity And Mortality ◽  
Term Care ◽  
Care Facilities ◽  
Stratified Analysis

OBJECTIVE: To describe coronavirus disease 2019 (COVID-19) morbidity and mortality in long-term care facilities (LTCFs) in the state of Bahia, Brazil. METHODS: This is an ecological study involving identified and active LTCFs in Bahia, monitored by the Intersectoral Monitoring Commission of LTCFs. Data analysis included COVID-19 incidence among older residents and workers and COVID-19 hospitalization, fatality, and mortality rates among older residents. In addition to a global analysis of data from Bahia, a stratified analysis compared (i) the East macroregion with the rest of Bahia, and (ii) private LTCFs with philanthropic ones. RESULTS: Our sample consisted of 175 LTCFs, more than half located in the East macroregion (n = 99). Most facilities declared themselves as philanthropic (n = 94) or private (n = 59). From April/2020 to June/2021, COVID-19 incidence was 30.71% among residents and 19.86% among LTCF workers. Considering older residents, mortality was 3.57% and fatality was 11.63%. Incidence was lower in the East macroregion, for older residents (relative risk [RR] = 0.77; 95% confidence interval [CI] 0.68–0.87) and LTCF workers (RR = 0.70; 95%CI 0.59–0.83). The hospitalization rate due to COVID-19 was 19.97%, being higher in private LTCFs (RR = 1.61; 95%CI 1.30–2.00). CONCLUSIONS: This study reveals that COVID-19 morbidity and mortality in LTCFs in Bahia were consistent with the wide ranges described in the literature, although case fatality was lower than expected. This demonstrates the importance of strategies to coordinate, identify, assess, and target support for LTCFs, highlighting the need for stronger public policies.

Epidemiological and genetic characteristics of norovirus outbreaks in long-term care facilities, 2003–2006

2010 ◽  
Vol 139 (2) ◽  
pp. 286-294 ◽  
Author(s):  
N. A. ROSENTHAL ◽  
L. E. LEE ◽  
B. A. J. VERMEULEN ◽  
K. HEDBERG ◽  
W. E. KEENE ◽  
...  
Keyword(s):  
Long Term Care ◽  
Laboratory Data ◽  
Case Fatality ◽  
Term Care ◽  
Genetic Characteristics ◽  
Duration Of Illness ◽  
Care Facilities ◽  
Polymerase Chain ◽  
The Impact

SUMMARYTo identify the epidemiological and genetic characteristics of norovirus (NoV) outbreaks and estimate the impact of NoV infections in an older population, we analysed epidemiological and laboratory data collected using standardized methods from long-term care facilities (LTCFs) during 2003–2006. Faecal specimens were tested for NoV by real-time reverse transcriptase–polymerase chain reaction. NoV strains were genotyped by sequencing. Of the 234 acute gastroenteritis (AGE) outbreaks reported, 163 (70%) were caused by NoV. The annual attack rate of outbreak-associated NoV infection in LTCF residents was 4%, with a case-hospitalization rate of 3·1% and a case-fatality rate of 0·5%. GII.4 strains accounted for 84% of NoV outbreaks. Median duration of illness was longer for GII.4 infections than non-GII.4 infections (33 vs. 24 h, P<0·001). Emerging GII.4 strains (Hunter/2004, Minerva/2006b, Terneuzen/2006a) gradually replaced the previously dominant strain (Farmington Hills/2002) during 2004–2006. NoV GII.4 strains are now associated with the majority of AGE outbreaks in LTCFs and prolonged illness in Oregon.

scholarly journals COVID ‐19 transmission and case fatality in long‐term care facilities during the epidemic first wave

2021 ◽  
Author(s):  
Teresa Leão ◽  
Milton Severo ◽  
Henrique Barros ◽  
Alice Magalhães ◽  
Bernardo Gomes ◽  
...  
Keyword(s):  
Long Term Care ◽  
Case Fatality ◽  
Term Care ◽  
Care Facilities

scholarly journals Epidemiological characteristics of influenza-like illness outbreaks in long-term care facilities of the state of São Paulo, Brazil

2021 ◽  
Vol 15 ◽  
Author(s):  
Pamella Cristina de Carvalho Lucas ◽  
Yeda Aparecida de Oliveira Duarte ◽  
Eliana Tiemi Masuda ◽  
Camila Martins Trevisan ◽  
Raquel Gardini Sanches Palasio ◽  
...  
Keyword(s):  
Older Adults ◽  
Older People ◽  
Long Term Care ◽  
Sao Paulo ◽  
The State ◽  
Term Care ◽  
Influenza Like Illness ◽  
Care Facilities ◽  
Epidemiological Characteristics

Long-term care facilities for older adults present a high risk of outbreaks since they concentrate often more frail and vulnerable individuals. OBJECTIVE: To describe the epidemiological characteristics of influenza-like illness outbreaks and cases among older people in long-term care facilities in the state of São Paulo, Brazil. METODS: The analysis was performed through an exploratory and descriptive approach, with records from the outbreak module of the National System of Notifiable Diseases between January 2020 and June 2021. RESULTS: Outbreaks of influenza-like illness in this department represented 24.93% of all notifications. The highest concentration was seen in the state capital and metropolitan area. A total of 1 018 confirmed outbreaks were observed, involving 6 110 cases and 1 240 deaths among older people. Of these cases, 71.67% were confirmed for coronavirus disease 19 (COVID-19), 12.77% for the influenza virus, and 15.56% for other respiratory viruses. The percentages regarding death outcomes were similar, with a 20.29% lethality of influenza-like illness. Within the studied group, the older adults were the most affected. A statistical difference was observed between cases and deaths. CONCLUSIONS: Owing to the current scenario and the known vulnerabilities of these facilities, there is an urgent need for joint and articulated action by various administrative levels in order to minimize the devastating effects of influenza-like illness outbreaks (especially of COVID- 19) in older adults at long-term care homes. The strengthening of information systems and their interoperability are considered of utmost importance in order to improve the quality of information on outbreaks, which is essential during a pandemic.

scholarly journals A rapid systematic review of measures to protect older people in long-term care facilities from COVID-19

BMJ Open ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. e047012
Author(s):  
Kate Frazer ◽  
Lachlan Mitchell ◽  
Diarmuid Stokes ◽  
Ella Lacey ◽  
Eibhlin Crowley ◽  
...  
Keyword(s):  
Systematic Review ◽  
Nursing Homes ◽  
Older People ◽  
Outcome Measures ◽  
Long Term Care ◽  
Morbidity And Mortality ◽  
Secondary Outcome ◽  
Term Care ◽  
Care Facilities

ObjectivesThe global COVID-19 pandemic produced large-scale health and economic complications. Older people and those with comorbidities are particularly vulnerable to this virus, with nursing homes and long term care facilities (LTCF) experiencing significant morbidity and mortality associated with COVID-19 outbreaks. The aim of this rapid systematic review was to investigate measures implemented in LTCF to reduce transmission of COVID-19 and their effect on morbidity and mortality of residents, staff and visitors.SettingLong-term care facilities.ParticipantsResidents, staff and visitors of facilities.Primary and secondary outcome measuresDatabases (PubMed, EMBASE, CINAHL, Cochrane Databases and repositories and MedRXiv prepublished database) were systematically searched from inception to 27 July 2020 to identify studies reporting assessment of interventions to reduce transmission of COVID-19 in nursing homes among residents, staff or visitors. Outcome measures include facility characteristics, morbidity data, case fatalities and transmission rates. Due to study quality and heterogeneity, no meta-analysis was conducted.ResultsThe search yielded 1414 articles, with 38 studies included. Reported interventions include mass testing, use of personal protective equipment, symptom screening, visitor restrictions, hand hygiene and droplet/contact precautions, and resident cohorting. Prevalence rates ranged from 1.2% to 85.4% in residents and 0.6% to 62.6% in staff. Mortality rates ranged from 5.3% to 55.3% in residents.ConclusionsNovel evidence in this review details the impact of facility size, availability of staff and practices of operating between multiple facilities, and for-profit status of facilities as factors contributing to the size and number of COVID-19 outbreaks. No causative relationships can be determined; however, this review provides evidence of interventions that reduce transmission of COVID-19 in LTCF.PROSPERO registration numberCRD42020191569.

scholarly journals Results of a hospitalization policy of asymptomatic and pre-symptomatic COVID-19-positive long-term care facility residents in the province of Salzburg—a report from the AGMT COVID-19 Registry

GeroScience ◽  
2021 ◽  
Author(s):  
Florian Huemer ◽  
Gabriel Rinnerthaler ◽  
Benedikt Jörg ◽  
Patrick Morre ◽  
Birgit Stegbuchner ◽  
...  
Keyword(s):  
Long Term Care ◽  
Tumor Therapy ◽  
Case Fatality ◽  
Care Facility ◽  
Early Warning Score ◽  
Term Care ◽  
Term Care Facility ◽  
Long Term Care Facility ◽  
Care Facilities

AbstractCOVID-19-associated case fatality rates up to 48% were reported among nursing facility residents. During the first wave of the COVID-19 pandemic, routine SARS-CoV-2 testing in long-term care facilities in the Province of Salzburg and centralized hospitalization in the COVID-19 unit of the Paracelsus Medical University Salzburg (Austria) irrespective of symptoms was implemented. Baseline characteristics and the course of COVID-19 disease were assessed among hospitalized long-term care facility residents within the COVID-19 Registry of the Austrian Group Medical Tumor Therapy (AGMT; NCT04351529). Between the 24th of March and the 20th of April 2020, 50 COVID-19-positive residents were hospitalized. The median age was 84.5 years (range: 79–88) and the median number of comorbidities and baseline medication classes was 6 (IQR: 4–7) and 5 (IQR: 3–6), respectively. At admission, 31 residents (62%) were symptomatic, nine residents (18%) pre-symptomatic whereas ten residents (20%) remained asymptomatic. The 30-day mortality rate from hospitalization was 32% and significantly higher in symptomatic residents at admission when compared to asymptomatic residents including pre-symptomatic residents (48% [95% CI: 27–63%] versus 5% [95% CI: 0–15%], p=0.006). The Early Warning Score (EWS) at admission was associated with 30-day mortality: high risk: 100%, intermediate risk: 50% (95% CI: 0–78%), and low risk: 21% (95% CI: 7-32%) (p<0.001). In light of comparably low mortality rates between asymptomatic and pre-symptomatic hospitalized COVID-19-positive residents, we suggest the supply of comparable intensity and quality of monitoring and care in long-term care facilities as an alternative to immediate hospitalization upon a positive COVID-19 test in asymptomatic residents.

scholarly journals Immunogenicity of SARS-CoV-2 Vaccine in Dialysis

2021 ◽  
Author(s):  
Eduardo Lacson ◽  
Christos P Argyropoulos ◽  
Harold J Manley ◽  
Gideon Aweh ◽  
Andrew I Chin ◽  
...  
Keyword(s):  
High Risk ◽  
Long Term Care ◽  
Morbidity And Mortality ◽  
Dialysis Patients ◽  
Term Care ◽  
Seropositive Rate ◽  
Care Facilities ◽  
Maximum Titer ◽  
Maintenance Dialysis

Abstract Importance: Patients receiving maintenance dialysis patients are at high risk for morbidity and mortality from COVID-19. The immunogenicity of SARS-CoV-2 mRNA vaccines is unknown in this vulnerable population where immune compromise is common. Objective: To determine seroresponse to vaccination against SARS-CoV-2 utilizing mRNA vaccines among patients receiving maintenance dialysis. Design: Retrospective observational study. Setting: Dialysis Clinic, Inc. (DCI) outpatient dialysis clinics in the United States. Participants: All patients receiving maintenance dialysis that received two doses of SARS-CoV-2 mRNA vaccines with SARS-CoV-2 spike-antibody test results drawn at least 14 days after the second dose, as documented in the electronic health record through March 18, 2021. Exposure: Two doses of BNT162b2/Pfizer or of mRNA-1273/Moderna vaccines administered per manufacturer recommendations. Main Outcomes and Measures: Levels of immunoglobulin-G against the receptor binding domain of the S1 subunit of SARS-CoV-2 spike antigen (seropositive: 2 or greater) using FDA-approved semi-quantitative chemiluminescent assay (ADVIA Centaur XP/XPT COV2G). The DCI clinical protocol for in-clinic administration included baseline and follow-up levels although initial administration of the vaccine occurred primarily elsewhere (e.g. long-term care facilities, hospitals, etc.) during the evaluation period. Hence, only post-vaccination antibody levels were reported. Results: Among 186 patients receiving maintenance dialysis from 32 clinics in 8 states tested an average of 23 days after receiving 2 vaccine doses, mean age was 68 years, with 47% women, 21% Black, 26% residents in long-term care facilities and 97% undergoing in-center hemodialysis. Overall seropositive rate was 165/186 (88.7%) with 70% at maximum titer and with no significant difference in seropositivity between BNT162b2/Pfizer (N=148) and mRNA-1273/Moderna (N=18) vaccines (88.1% vs. 94.4%, p=0.42). Among patients with COVID-19 history, seropositive rate was 38/38 (100%) with 97% at maximum titer. Conclusions and Relevance: Most patients receiving maintenance dialysis were seropositive after two doses of BNT162b2/Pfizer or mRNA-1273/Moderna vaccine. Early evidence suggests that vaccinated dialysis patients with prior COVID-19 develop robust antibody response. These results support an equitable and aggressive vaccination strategy for all eligible patients receiving maintenance dialysis, regardless of age, sex, race, ethnicity, or disability, to prevent the extremely high morbidity and mortality associated with COVID-19 in this high risk population.

scholarly journals Health care strategies in long-term care facilities in Bahia State, Brazil

2021 ◽  
Vol 15 ◽  
Author(s):  
Meirelayne Borges Duarte ◽  
João Victor Nunes Freitas ◽  
Rafaela Andrade Correia ◽  
Mônica Hupsel Frank ◽  
Helena Patáro de Oliveira Novaes ◽  
...  
Keyword(s):  
Public Health ◽  
Health Care ◽  
Long Term Care ◽  
The State ◽  
Lower Percentage ◽  
Care Providers ◽  
Term Care ◽  
Care Facilities ◽  
Health Care Strategies

OBJECTIVE: To describe health care strategies for older people living in long-term care facilities (LTCFs) in Bahia state, Brazil. METHODS: This is an ecological study involving LTCFs identified in Bahia state, which were invited to participate in a survey conducted between April and June 2021. The variables of interest were LTCF characteristics, health care strategies, visits received from national public health system (SUS, in Portuguese) teams, and health care actions taken by SUS. A comparative analysis was performed between LTCFs located in the East macro-region and other parts of the state, in general and also stratified by funding type (private and non-private). RESULTS: The sample consisted of 177 LTCFs, more than half of them were located in the East macro-region, seat of the state capital. Most facilities declared themselves as non-private (68%). Less than one-third of the LTCFs had their own health teams. Although 67% of LTCFs reported some health care provided by SUS, only 49% reported clinical consultations, with even lower percentages for other SUS actions, except for vaccination (91%). The East macro-region had a lower percentage of LTCFs accompanied by a SUS team, and the highest percentage of LTCFs with supplementary health insurance. CONCLUSIONS: This study shows the limited access of LTCF residents to essential health services, due to a general neglect of this population by public health care providers. The inadequacy of public policies to support LTCFs has important consequences for the quality of care offered to residents.

scholarly journals Clinical outcomes of SARS-CoV-2 pandemic in long-term care facilities for people with epilepsy: observational study

2020 ◽  
Author(s):  
Simona Balestrini ◽  
Matthias J Koepp ◽  
Sonia Gandhi ◽  
Hannah M Rickman ◽  
Gee Yen Shin ◽  
...  
Keyword(s):  
Long Term Care ◽  
Case Fatality ◽  
Control Measures ◽  
Care Staff ◽  
Specialist Care ◽  
Term Care ◽  
Infection Control Measures ◽  
Care Facilities ◽  
Observation Period

AbstractObjectivesCOVID-19 is spreading in long-term care facilities with devastating outcomes worldwide, especially for people with chronic health conditions. There is a pressing need to adopt effective measures prevention and containment of in such settings.DesignRetrospective cohort study assessing the effect of enhanced surveillance and early preventative strategies and comparing outcomes for people with severe epilepsy and other comorbiditiesSettingThree long-term care facilities: Chalfont Centre for Epilepsy (CCE), St. Elisabeth (STE), and The Meath (TM) with different models of primary and specialist care involvement, in the United KingdomParticipants286 long-term residents (age range 19–91 years), 740 carers who had been in contact with the residents during the observation period between 16 March and 05 June 2020.InterventionsEarly preventative and infection control measures with identification and isolation of symptomatic cases, with additional enhanced surveillance and isolation of asymptomatic residents and carers at one site (CCE)Main outcome measuresInfection rate for SARS-CoV-2 among residents and carers, asymptomatic rate and case fatality rate, if available.ResultsDuring a 12-week observation period, we identified 29 people (13 residents) who were SARS-CoV-2 positive with confirmed outbreaks amongst residents in two long-term care facilities (CCE, STE). At CCE, two out of 98 residents were symptomatic and tested positive, one of whom died. A further seven individuals testing positive on weekly enhanced surveillance had a completely asymptomatic course. One asymptomatic carer tested positive after contact with confirmed COVID-19 patients in another institution. Since 30 April 2020, during on-site weekly enhanced surveillance all 275 caregivers tested repeatedly negative. At STE, three out of 146 residents were symptomatic and tested positive, a fourth tested positive during hospital admission for symptoms not related to COVID-19. Since April 6, 2020, 105/215 carers presenting with typical symptoms for COVID-19 were tested, of whom 15 tested positive. At TM, testing of symptomatic carers only started from early/mid-April, whilst on-site testing, even of symptomatic residents, was not available until recently.During the observation period, eight of 80 residents were symptomatic but none was tested. Twenty-six of 250 carers were symptomatic and were tested, of whom two tested positive.ConclusionsInfection outbreaks in long-term care facilities for vulnerable people with epilepsy can be quickly contained, but only if asymptomatic cases are identified through enhanced surveillance at individual and care staff level. We observed a low rate of morbidity and mortality which confirmed that preventative measures with isolation of suspected and confirmed cases of COVID-19 can reduce resident-to-resident and reverse resident-to-carer transmission.

scholarly journals High vaccine effectiveness against coronavirus disease 2019 (COVID-19) and severe disease among residents and staff of long-term care facilities in Norway, November 2020–June 2021

2022 ◽  
Vol 2 (1) ◽  
Author(s):  
Jostein Starrfelt ◽  
Anders Skyrud Danielsen ◽  
Oliver Kacelnik ◽  
Anita Wang Børseth ◽  
Elina Seppälä ◽  
...  
Keyword(s):  
Long Term Care ◽  
Severe Disease ◽  
Vaccine Effectiveness ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Term Care ◽  
Care Facilities

Abstract Coronavirus disease 2019 (COVID-19) causes high morbidity and mortality in long-term care facilities (LTCFs). COVID-19 vaccine effectiveness against infection was 81.5% and 81.4% among fully vaccinated residents and staff in LTCFs. The vaccine effectiveness against COVID-19-associated death was 93.1% among residents, and no hospitalizations occurred among fully vaccinated staff.

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