scholarly journals High vaccine effectiveness against coronavirus disease 2019 (COVID-19) and severe disease among residents and staff of long-term care facilities in Norway, November 2020–June 2021

2022 ◽  
Vol 2 (1) ◽  
Author(s):  
Jostein Starrfelt ◽  
Anders Skyrud Danielsen ◽  
Oliver Kacelnik ◽  
Anita Wang Børseth ◽  
Elina Seppälä ◽  
...  
Keyword(s):  
Long Term Care ◽  
Severe Disease ◽  
Vaccine Effectiveness ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Term Care ◽  
Care Facilities

Abstract Coronavirus disease 2019 (COVID-19) causes high morbidity and mortality in long-term care facilities (LTCFs). COVID-19 vaccine effectiveness against infection was 81.5% and 81.4% among fully vaccinated residents and staff in LTCFs. The vaccine effectiveness against COVID-19-associated death was 93.1% among residents, and no hospitalizations occurred among fully vaccinated staff.

scholarly journals High vaccine effectiveness against COVID-19 infection and severe disease among residents and staff of long-term care facilities in Norway, November - June 2021

2021 ◽  
Author(s):  
Jostein Starrfelt ◽  
Anders S Danielsen ◽  
Oliver Kacelnik ◽  
Anita Wang Borseth ◽  
Elina Seppala ◽  
...  
Keyword(s):  
Health Care Workers ◽  
Long Term Care ◽  
Severe Disease ◽  
Vaccine Dose ◽  
Vaccine Effectiveness ◽  
High Morbidity ◽  
Term Care ◽  
Care Workers ◽  
Care Facilities

COVID-19 has caused high morbidity and mortality in long-term care facilities (LTCFs) worldwide. We estimated vaccine effectiveness (VE) among residents and health care workers (HCWs) in LTCFs using Cox regressions. The VE against SARS-CoV-2 infection was 81.5 (95%CI: 75.3-86.1 82.7%) and 81.4% (95%CI: 74.5-86.4%) 7 days or more after 2nd vaccine dose among residents and staff respectively. The VE against COVID-19 associated death was 93.1% among residents, no hospitalisations occurred among HCW 7 days or more after 2nd dose.

scholarly journals Impact of B.1.351 (beta) SARS-CoV-2 variant on BNT162b2 mRNA vaccine effectiveness in long-term care facilities of eastern France: a retrospective cohort study

2021 ◽  
Author(s):  
Benjamin Lefevre ◽  
Laura Tondeur ◽  
Yoann Madec ◽  
Rebecca Grant ◽  
Bruno Lina ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Long Term Care ◽  
Multivariable Analysis ◽  
Winter Season ◽  
Vaccine Effectiveness ◽  
Term Care ◽  
Care Facilities

Abstract Background: We aimed to assess the effectiveness of the BNT162b2 mRNA vaccine against B.1.351 (beta) variant among residents of long-term care facilities (LCTFs) in eastern France. Methods: We used routinely collected surveillance and COVID-19 vaccination data to conduct a retrospective cohort study of SARS-CoV-2 B.1.351 infection incidence and vaccine effectiveness among LCTFs residents in eastern France between 15 January and 19 May 2021. Data from secondary RT-PCR screening were used to identify B.1.351 variants. Findings: Included in our analysis were 378 residents from five LCTFs: 287 (76%) females, with median (IQR) age of 89 (83-92) years. Two B.1.351 outbreaks took place in LTCFs in which more than 70% of residents had received two doses of BNT162b2 mRNA vaccine, which included 11 cases of severe disease and six deaths among those who had received two doses. Vaccine effectiveness (95% CI) seven days after the second dose of vaccine was 49% (14-69) against any infection with B.1.351 and 86% (67-94) against severe forms of COVID-19. In multivariable analysis, females were less likely to develop severe forms of disease (IRR = 0.35, 95% CI = 0.20-0.63). Interpretation: We observed reduced vaccine effectiveness associated with B.1.351, as well as B.1.351 outbreaks in two LTCFs among individuals who had received two doses of vaccine. Our findings highlight the need to maintain SARS-CoV-2 surveillance in these high-risk settings beyond the current COVID-19 mass vaccination campaign, and advocate for a booster vaccine dose prior to the next winter season.

scholarly journals Beta SARS-CoV-2 variant and BNT162b2 vaccine effectiveness in long-term care facilities in France

2021 ◽  
Author(s):  
Benjamin Lefèvre ◽  
Laura Tondeur ◽  
Yoann Madec ◽  
Rebecca Grant ◽  
Bruno Lina ◽  
...  
Keyword(s):  
Long Term Care ◽  
Vaccine Effectiveness ◽  
Term Care ◽  
Care Facilities

scholarly journals Changes in COVID-19 outbreak severity and duration in long-term care facilities following vaccine introduction, England, November 2020 to June 2021

2021 ◽  
Vol 26 (46) ◽  
Author(s):  
Rebecca Giddings ◽  
Maria Krutikov ◽  
Tom Palmer ◽  
Christopher Fuller ◽  
Borscha Azmi ◽  
...  
Keyword(s):  
Long Term Care ◽  
Vaccine Coverage ◽  
Vaccine Effectiveness ◽  
Term Care ◽  
Vaccine Introduction ◽  
Care Facilities ◽  
The Impact

We describe the impact of changing epidemiology and vaccine introduction on characteristics of COVID-19 outbreaks in 330 long-term care facilities (LTCF) in England between November 2020 and June 2021. As vaccine coverage in LTCF increased and national incidence declined, the total number of outbreaks and outbreak severity decreased across the LTCF. The number of infected cases per outbreak decreased by 80.6%, while the proportion of outbreaks affecting staff only increased. Our study supports findings of vaccine effectiveness in LTCF.

scholarly journals A methicillin-rezisztens Staphylococcus aureus gyakorisága és kockázati tényezői a bentlakásos szociális intézményekben. Nemzetközi kitekintés

2016 ◽  
Vol 157 (27) ◽  
pp. 1071-1078
Author(s):  
Rita Szabó
Keyword(s):  
Staphylococcus Aureus ◽  
Long Term Care ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Chronic Wounds ◽  
Cochrane Library ◽  
High Morbidity ◽  
Term Care ◽  
Methicillin Resistant ◽  
Care Facilities

Introduction: Methicillin-resistant Staphylococcus aureus is one of the most important pathogens of healthcare and long-term care-associated infections over the world, resulting high morbidity, mortality and extra costs in these settings. Aim: The authors analyze the prevalence and predisposing factors of methicillin-resistant Staphylococcus aureus in long-term care facilities. Method: Systematic review using PubMed, ScienceDirect and Cochrane Library CENTRAL databases between January 1, 2006 and December 31, 2015 was performed. Results: In the past ten years methicillin-resistant Staphylococcus aureus prevalence in European long-term care facilities (12.6%) was lower than in North America (33.9%). The most frequent predisposing factor was previous antimicrobial therapy, hospital admission and infection/colonisation, chronic wounds, and high care need. Conclusions: Based on the results, the prevention and control of methicillin-resistant Staphylococcus aureus is an important public health priority in the European and Hungarian long-term care facilities. Orv. Hetil., 2016, 157(27), 1071–1078.

scholarly journals COVID-19 morbimortality in long-term care facilities in the state of Bahia, Brazil

2021 ◽  
Vol 15 ◽  
Author(s):  
Meirelayne Borges Duarte ◽  
Isabela Lôbo Duarte ◽  
Lucas Maia Scardino Faria ◽  
Mônica Hupsel Frank ◽  
Helena Patáro de Oliveira Novaes ◽  
...  
Keyword(s):  
Ecological Study ◽  
Long Term Care ◽  
Global Analysis ◽  
Case Fatality ◽  
The State ◽  
Morbidity And Mortality ◽  
Term Care ◽  
Care Facilities ◽  
Stratified Analysis

OBJECTIVE: To describe coronavirus disease 2019 (COVID-19) morbidity and mortality in long-term care facilities (LTCFs) in the state of Bahia, Brazil. METHODS: This is an ecological study involving identified and active LTCFs in Bahia, monitored by the Intersectoral Monitoring Commission of LTCFs. Data analysis included COVID-19 incidence among older residents and workers and COVID-19 hospitalization, fatality, and mortality rates among older residents. In addition to a global analysis of data from Bahia, a stratified analysis compared (i) the East macroregion with the rest of Bahia, and (ii) private LTCFs with philanthropic ones. RESULTS: Our sample consisted of 175 LTCFs, more than half located in the East macroregion (n = 99). Most facilities declared themselves as philanthropic (n = 94) or private (n = 59). From April/2020 to June/2021, COVID-19 incidence was 30.71% among residents and 19.86% among LTCF workers. Considering older residents, mortality was 3.57% and fatality was 11.63%. Incidence was lower in the East macroregion, for older residents (relative risk [RR] = 0.77; 95% confidence interval [CI] 0.68–0.87) and LTCF workers (RR = 0.70; 95%CI 0.59–0.83). The hospitalization rate due to COVID-19 was 19.97%, being higher in private LTCFs (RR = 1.61; 95%CI 1.30–2.00). CONCLUSIONS: This study reveals that COVID-19 morbidity and mortality in LTCFs in Bahia were consistent with the wide ranges described in the literature, although case fatality was lower than expected. This demonstrates the importance of strategies to coordinate, identify, assess, and target support for LTCFs, highlighting the need for stronger public policies.

scholarly journals COVID-19 and Ontario’s Long-Term Care Homes

2020 ◽  
Author(s):  
Nathan M. Stall ◽  
Kevin A. Brown ◽  
Aaron Jones ◽  
Andrew P. Costa ◽  
Vanessa Allen ◽  
...  
Keyword(s):  
Working Conditions ◽  
Long Term Care ◽  
Morbidity And Mortality ◽  
High Morbidity ◽  
Temporary Housing ◽  
Term Care ◽  
High Burden ◽  
Second Homes ◽  
Temporary Staffing

Ontario long-term care (LTC) home residents have experienced disproportionately high morbidity and mortality, both from COVID-19 and from the conditions associated with the COVID-19 pandemic. There are several measures that could be effective in preventing COVID-19 outbreaks, hospitalizations, and deaths in Ontario’s LTC homes, if implemented. First, temporary staffing could be minimized by improving staff working conditions. Second, homes could be further decrowded by a continued disallowance of three- and four-resident rooms and additional temporary housing for the most crowded homes. Third, the risk of SARS-CoV-2 infection in staff could be minimized by approaches that reduce the risk of transmission in communities with a high burden of COVID-19.

scholarly journals A rapid systematic review of measures to protect older people in long-term care facilities from COVID-19

BMJ Open ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. e047012
Author(s):  
Kate Frazer ◽  
Lachlan Mitchell ◽  
Diarmuid Stokes ◽  
Ella Lacey ◽  
Eibhlin Crowley ◽  
...  
Keyword(s):  
Systematic Review ◽  
Nursing Homes ◽  
Older People ◽  
Outcome Measures ◽  
Long Term Care ◽  
Morbidity And Mortality ◽  
Secondary Outcome ◽  
Term Care ◽  
Care Facilities

ObjectivesThe global COVID-19 pandemic produced large-scale health and economic complications. Older people and those with comorbidities are particularly vulnerable to this virus, with nursing homes and long term care facilities (LTCF) experiencing significant morbidity and mortality associated with COVID-19 outbreaks. The aim of this rapid systematic review was to investigate measures implemented in LTCF to reduce transmission of COVID-19 and their effect on morbidity and mortality of residents, staff and visitors.SettingLong-term care facilities.ParticipantsResidents, staff and visitors of facilities.Primary and secondary outcome measuresDatabases (PubMed, EMBASE, CINAHL, Cochrane Databases and repositories and MedRXiv prepublished database) were systematically searched from inception to 27 July 2020 to identify studies reporting assessment of interventions to reduce transmission of COVID-19 in nursing homes among residents, staff or visitors. Outcome measures include facility characteristics, morbidity data, case fatalities and transmission rates. Due to study quality and heterogeneity, no meta-analysis was conducted.ResultsThe search yielded 1414 articles, with 38 studies included. Reported interventions include mass testing, use of personal protective equipment, symptom screening, visitor restrictions, hand hygiene and droplet/contact precautions, and resident cohorting. Prevalence rates ranged from 1.2% to 85.4% in residents and 0.6% to 62.6% in staff. Mortality rates ranged from 5.3% to 55.3% in residents.ConclusionsNovel evidence in this review details the impact of facility size, availability of staff and practices of operating between multiple facilities, and for-profit status of facilities as factors contributing to the size and number of COVID-19 outbreaks. No causative relationships can be determined; however, this review provides evidence of interventions that reduce transmission of COVID-19 in LTCF.PROSPERO registration numberCRD42020191569.

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