COVID-19 Data Analysis using Chest X-Ray

The COVID-19 pandemic has caused large-scale outbreaks in more than 150 countries worldwide, causing massive damage to the livelihood of many people. The capacity to identify contaminated patients early and get unique treatment is quite possibly the primary stride in the battle against COVID-19. One of the quickest ways to diagnose patients is to use radiography and radiology images to detect the disease. Early studies have shown that chest X-rays of patients infected with COVID-19 have unique abnormalities. To identify COVID-19 patients from chest X-ray images, we used various deep learning models based on previous studies. We first compiled a data set of 2,815 chest radiographs from public sources. The model produces reliable and stable results with an accuracy of 91.6%, a Positive Predictive Value of 80%, a Negative Predictive Value of 100%, specificity of 87.50%, and Sensitivity of 100%. It is observed that the CNN-based architecture can diagnose COVID-19 disease. The parameters’ outcomes can be further improved by increasing the dataset size and by developing the CNN-based architecture for training the model.

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COVID-19 Data Analysis using Chest X-ray

International Journal of Advanced Medical Sciences and Technology - Regular Issue ◽

10.35940/ijamst.c3018.081421 ◽

2021 ◽

Vol 1 (4) ◽

pp. 5-10

Author(s):

Ishtiaque Ahmed ◽

◽

Manan Darda ◽

Neha Tikyani ◽

Rachit Agrawal ◽

...

Keyword(s):

Deep Learning ◽

Data Analysis ◽

Predictive Value ◽

Large Scale ◽

X Rays ◽

Learning Models ◽

Data Set ◽

X Ray ◽

Dataset Size ◽

Chest X Ray

The COVID-19 pandemic has caused large-scale outbreaks in more than 150 countries worldwide, causing massive damage to the livelihood of many people. The capacity to identify contaminated patients early and get unique treatment is quite possibly the primary stride in the battle against COVID-19. One of the quickest ways to diagnose patients is to use radiography and radiology images to detect the disease. Early studies have shown that chest X-rays of patients infected with COVID-19 have unique abnormalities. To identify COVID-19 patients from chest X-ray images, we used various deep learning models based on previous studies. We first compiled a data set of 2,815 chest radiographs from public sources. The model produces reliable and stable results with an accuracy of 91.6%, a Positive Predictive Value of 80%, a Negative Predictive Value of 100%, specificity of 87.50%, and Sensitivity of 100%. It is observed that the CNN-based architecture can diagnose COVID19 disease. The parameters’ outcomes can be further improved by increasing the dataset size and by developing the CNN-based architecture for training the model.

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Detecting Coronavirus from Chest X-rays Using Transfer Learning

COVID ◽

10.3390/covid1010034 ◽

2021 ◽

Vol 1 (1) ◽

pp. 403-415

Author(s):

Abeer Badawi ◽

Khalid Elgazzar

Keyword(s):

Deep Learning ◽

Binary Classification ◽

Healthcare Providers ◽

Large Set ◽

X Rays ◽

Learning Models ◽

X Ray ◽

Chest X Ray ◽

Multi Class Classification ◽

Novel Coronavirus

Coronavirus disease (COVID-19) is an illness caused by a novel coronavirus family. One of the practical examinations for COVID-19 is chest radiography. COVID-19 infected patients show abnormalities in chest X-ray images. However, examining the chest X-rays requires a specialist with high experience. Hence, using deep learning techniques in detecting abnormalities in the X-ray images is presented commonly as a potential solution to help diagnose the disease. Numerous research has been reported on COVID-19 chest X-ray classification, but most of the previous studies have been conducted on a small set of COVID-19 X-ray images, which created an imbalanced dataset and affected the performance of the deep learning models. In this paper, we propose several image processing techniques to augment COVID-19 X-ray images to generate a large and diverse dataset to boost the performance of deep learning algorithms in detecting the virus from chest X-rays. We also propose innovative and robust deep learning models, based on DenseNet201, VGG16, and VGG19, to detect COVID-19 from a large set of chest X-ray images. A performance evaluation shows that the proposed models outperform all existing techniques to date. Our models achieved 99.62% on the binary classification and 95.48% on the multi-class classification. Based on these findings, we provide a pathway for researchers to develop enhanced models with a balanced dataset that includes the highest available COVID-19 chest X-ray images. This work is of high interest to healthcare providers, as it helps to better diagnose COVID-19 from chest X-rays in less time with higher accuracy.

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Deep Mining Generation of Lung Cancer Malignancy Models from Chest X-ray Images

Sensors ◽

10.3390/s21196655 ◽

2021 ◽

Vol 21 (19) ◽

pp. 6655

Author(s):

Michael Horry ◽

Subrata Chakraborty ◽

Biswajeet Pradhan ◽

Manoranjan Paul ◽

Douglas Gomes ◽

...

Keyword(s):

Lung Cancer ◽

Computer Vision ◽

Deep Learning ◽

Decision Tree ◽

Decision Trees ◽

Lung Nodules ◽

X Rays ◽

Learning Models ◽

X Ray ◽

Chest X Ray

Lung cancer is the leading cause of cancer death and morbidity worldwide. Many studies have shown machine learning models to be effective in detecting lung nodules from chest X-ray images. However, these techniques have yet to be embraced by the medical community due to several practical, ethical, and regulatory constraints stemming from the “black-box” nature of deep learning models. Additionally, most lung nodules visible on chest X-rays are benign; therefore, the narrow task of computer vision-based lung nodule detection cannot be equated to automated lung cancer detection. Addressing both concerns, this study introduces a novel hybrid deep learning and decision tree-based computer vision model, which presents lung cancer malignancy predictions as interpretable decision trees. The deep learning component of this process is trained using a large publicly available dataset on pathological biomarkers associated with lung cancer. These models are then used to inference biomarker scores for chest X-ray images from two independent data sets, for which malignancy metadata is available. Next, multi-variate predictive models were mined by fitting shallow decision trees to the malignancy stratified datasets and interrogating a range of metrics to determine the best model. The best decision tree model achieved sensitivity and specificity of 86.7% and 80.0%, respectively, with a positive predictive value of 92.9%. Decision trees mined using this method may be considered as a starting point for refinement into clinically useful multi-variate lung cancer malignancy models for implementation as a workflow augmentation tool to improve the efficiency of human radiologists.

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Cardiac or Infectious? Transfer Learning with Chest X-Rays for ER Patient Classification

10.1101/2020.04.11.20062091 ◽

2020 ◽

Cited By ~ 2

Author(s):

Jonathan Stubblefield ◽

Mitchell Hervert ◽

Jason Causey ◽

Jake Qualls ◽

Wei Dong ◽

...

Keyword(s):

Deep Learning ◽

Clinical Data ◽

Image Data ◽

Learning Model ◽

Patient Classification ◽

X Rays ◽

Data Set ◽

X Ray ◽

Chest X Ray ◽

Deep Learning Model

AbstractOne of the challenges with urgent evaluation of patients with acute respiratory distress syndrome (ARDS) in the emergency room (ER) is distinguishing between cardiac vs infectious etiologies for their pulmonary findings. We evaluated ER patient classification for cardiac and infection causes with clinical data and chest X-ray image data. We show that a deep-learning model trained with an external image data set can be used to extract image features and improve the classification accuracy of a data set that does not contain enough image data to train a deep-learning model. We also conducted clinical feature importance analysis and identified the most important clinical features for ER patient classification. This model can be upgraded to include a SARS-CoV-2 specific classification with COVID-19 patients data. The current model is publicly available with an interface at the web link: http://nbttranslationalresearch.org/.Data statementThe clinical data and chest x-ray image data for this study were collected and prepared by the residents and researchers of the Joint Translational Research Lab of Arkansas State University (A-State) and St. Bernards Medical Center (SBMC) Internal Medicine Residency Program. As data collection is on-going for the project stage-II of clinical testing, raw data is not currently available for data sharing to the public.EthicsThis study was approved by the St. Bernards Medical Center’s Institutional Review Board (IRB).

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A Novel Tuberculosis Prediction Model by Extracting Radiological Features Present in Chest X-ray Images Using Modified Discrete Grey Wolf Optimizer Based Segmentation

Journal of Medical Imaging and Health Informatics ◽

10.1166/jmihi.2021.3837 ◽

2021 ◽

Vol 11 (10) ◽

pp. 2519-2528

Author(s):

J. Senthil Kumar ◽

S. Appavu Alias Balamurugan ◽

S. Sasikala

Keyword(s):

Deep Learning ◽

Image Interpretation ◽

Grey Wolf Optimizer ◽

Gray Wolf ◽

X Rays ◽

Grey Wolf ◽

Data Set ◽

X Ray ◽

Novel Approach ◽

Chest X Ray

In 2018, an invariant numbers ranging from 10 million people suffered from Tuberculosis (TB) approximately that has remained quite stable in recent years, based on the WHO 2019 survey report. This infection rate differs invariable among countries, from less than 5 to more than 500 new infections per 1,00,000 people each year, with a global average of around 130. Around 1.2 million HIV negative deaths existed in 2018. If this prevailing disease were diagnosed earlier, the death rate would have been under control, however sophisticated testing techniques tend to be cost prohibitive of wider acceptance. Some of the most important methods for TB diagnosis include thoracic X-ray image interpretation through image processing by the identification of various structures on thoracic X-rays and anomaly assessment is an important stage in computer-aided diagnosis systems. Chest form and size may contain indications for serious disorders such as pneumothorax, pneumoconiosis, tuberculosis and emphysema. Substantial work might have contributed to simplify diagnosis through implementing various statistical strategies to medical images, minimizing overtime and dramatically lowering overhead costs. In addition, recent advances in deep learning have provided magnificent results in the detection of images in different fields, but their use in diagnose TB remains limited. Thus, this work focuses on the development of a novel approach in disease detection. The concepts presented in this work are placed into practice and linked to current literature. We also proposed an automatic approach in conventional poster anterior chest X-rays for TB identification and diagnosis. We use the chest X-ray image with modified discrete grey wolf optimizer for segmentation techniques to eradicate abnormal areas and shape abnormality. We extract various features from the X-ray image with a shear let extraction that allows the image to be classified as normal or abnormal, based on a deep learning classifier, via the improved residual VGG net CNN with big data. Using Shenzhen Hospital Chest X-ray data set we test the efficiency of our system. The suggested technique has competitive results with comparatively shorter training period and greater precision depending on Masientropy based discrete gray wolf optimizer segmentation with an improved residual VGG net CNN. All the simulations are carried out in a mat lab environment.

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Comparison of Classification Models Based on Deep learning on COVID-19 Chest X-Rays

Journal of Physics Conference Series ◽

10.1088/1742-6596/2161/1/012078 ◽

2022 ◽

Vol 2161 (1) ◽

pp. 012078

Author(s):

Pallavi R Mane ◽

Rajat Shenoy ◽

Ghanashyama Prabhu

Keyword(s):

Deep Learning ◽

Transfer Learning ◽

State Of The Art ◽

Cost Effective ◽

X Rays ◽

The Novel ◽

Learning Models ◽

X Ray ◽

Chest X Ray ◽

Fine Tune

Abstract COVID -19, is a deadly, dangerous and contagious disease caused by the novel corona virus. It is very important to detect COVID-19 infection accurately as quickly as possible to avoid the spreading. Deep learning methods can significantly improve the efficiency and accuracy of reading Chest X-Rays (CXRs). The existing Deep learning models with further fine tune provide cost effective, rapid, and better classification results. This paper tries to deploy well studied AI tools with modification on X-ray images to classify COVID 19. This research performs five experiments to classify COVID-19 CXRs from Normal and Viral Pneumonia CXRs using Convolutional Neural Networks (CNN). Four experiments were performed on state-of-the-art pre-trained models using transfer learning and one experiment was performed using a CNN designed from scratch. Dataset used for the experiments consists of chest X-Ray images from the Kaggle dataset and other publicly accessible sources. The data was split into three parts while 90% retained for training the models, 5% each was used in validation and testing of the constructed models. The four transfer learning models used were Inception, Xception, ResNet, and VGG19, that resulted in the test accuracies of 93.07%, 94.8%, 67.5%, and 91.1% respectively and our CNN model resulted in 94.6%.

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COVID-19 Pneumonia Detection Using Optimized Deep Learning Techniques

Diagnostics ◽

10.3390/diagnostics11111972 ◽

2021 ◽

Vol 11 (11) ◽

pp. 1972

Author(s):

Abul Bashar ◽

Ghazanfar Latif ◽

Ghassen Ben Brahim ◽

Nazeeruddin Mohammad ◽

Jaafar Alghazo

Keyword(s):

Deep Learning ◽

Transfer Learning ◽

Data Augmentation ◽

Learning Algorithm ◽

The Body ◽

X Rays ◽

X Ray ◽

Clinical Observations ◽

Dataset Size ◽

Chest X Ray

It became apparent that mankind has to learn to live with and adapt to COVID-19, especially because the developed vaccines thus far do not prevent the infection but rather just reduce the severity of the symptoms. The manual classification and diagnosis of COVID-19 pneumonia requires specialized personnel and is time consuming and very costly. On the other hand, automatic diagnosis would allow for real-time diagnosis without human intervention resulting in reduced costs. Therefore, the objective of this research is to propose a novel optimized Deep Learning (DL) approach for the automatic classification and diagnosis of COVID-19 pneumonia using X-ray images. For this purpose, a publicly available dataset of chest X-rays on Kaggle was used in this study. The dataset was developed over three stages in a quest to have a unified COVID-19 entities dataset available for researchers. The dataset consists of 21,165 anterior-to-posterior and posterior-to-anterior chest X-ray images classified as: Normal (48%), COVID-19 (17%), Lung Opacity (28%) and Viral Pneumonia (6%). Data Augmentation was also applied to increase the dataset size to enhance the reliability of results by preventing overfitting. An optimized DL approach is implemented in which chest X-ray images go through a three-stage process. Image Enhancement is performed in the first stage, followed by Data Augmentation stage and in the final stage the results are fed to the Transfer Learning algorithms (AlexNet, GoogleNet, VGG16, VGG19, and DenseNet) where the images are classified and diagnosed. Extensive experiments were performed under various scenarios, which led to achieving the highest classification accuracy of 95.63% through the application of VGG16 transfer learning algorithm on the augmented enhanced dataset with freeze weights. This accuracy was found to be better as compared to the results reported by other methods in the recent literature. Thus, the proposed approach proved superior in performance as compared with that of other similar approaches in the extant literature, and it made a valuable contribution to the body of knowledge. Although the results achieved so far are promising, further work is planned to correlate the results of the proposed approach with clinical observations to further enhance the efficiency and accuracy of COVID-19 diagnosis.

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Accessory pathway analysis using a multimodal deep learning model

Scientific Reports ◽

10.1038/s41598-021-87631-y ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Makoto Nishimori ◽

Kunihiko Kiuchi ◽

Kunihiro Nishimura ◽

Kengo Kusano ◽

Akihiro Yoshida ◽

...

Keyword(s):

Deep Learning ◽

Electrophysiological Study ◽

Accessory Pathway ◽

Learning Model ◽

X Rays ◽

X Ray ◽

Wpw Syndrome ◽

Chest X Ray ◽

Deep Learning Model ◽

Ecg Data

AbstractCardiac accessory pathways (APs) in Wolff–Parkinson–White (WPW) syndrome are conventionally diagnosed with decision tree algorithms; however, there are problems with clinical usage. We assessed the efficacy of the artificial intelligence model using electrocardiography (ECG) and chest X-rays to identify the location of APs. We retrospectively used ECG and chest X-rays to analyse 206 patients with WPW syndrome. Each AP location was defined by an electrophysiological study and divided into four classifications. We developed a deep learning model to classify AP locations and compared the accuracy with that of conventional algorithms. Moreover, 1519 chest X-ray samples from other datasets were used for prior learning, and the combined chest X-ray image and ECG data were put into the previous model to evaluate whether the accuracy improved. The convolutional neural network (CNN) model using ECG data was significantly more accurate than the conventional tree algorithm. In the multimodal model, which implemented input from the combined ECG and chest X-ray data, the accuracy was significantly improved. Deep learning with a combination of ECG and chest X-ray data could effectively identify the AP location, which may be a novel deep learning model for a multimodal model.

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