scholarly journals Hepatic carcinosarcoma with rhabdomyosarcoma: A case report and review of literature

2020 ◽  
Vol 7 (1) ◽  
pp. 40
Author(s):  
Gongbo Liang ◽  
Guangning Yan ◽  
Xuwen Lai ◽  
Huangwen Lai ◽  
Yunfeng Qian ◽  
...  

Objective To analyze the clinical and pathological manifestations of a hepatic carcinosarcoma case with rhabdomyosarcoma components (HCSR).Methods A case of HCSR was observed by macroscopy, microscopy, immunohistochemistry and electron microscopy, along with thorough review of correlated literatures.Results The tumor tends to occur in elder patients without differences on gender. Epigarstric sicknesses, AFP rising in serum, and a mass on the right liver shown in radiography are commonly initial signs. It was composed of both hepatic carcinoma and variously differentiated sarcoma components, with identifiable rhabdomyosarcoma. Immunohistochemistry showed that the hepatic carcinosarcoma was positive of epithelial markers and mesenchymatous component was diffuse positive of Vimentin, and mosaic positive of SDHB, CD117, while rhabdomyosarcoma was positive of muscular markers. Transmission electron microscopy showed the tumor had both epithelial and rhabdomyosarcoma ultra-microstructure.Conclusion HCSR is a very rare type and highly malignant tumor with a dismal prognosis, hardly demonstrating unique clinical manifestations. Diagnosis and differential diagnosis rely on combination of histomorphology, immunohistochemistry and ultra-microstructure observation.

1992 ◽  
Vol 262 (3) ◽  
pp. F367-F372 ◽  
Author(s):  
K. M. Denton ◽  
P. A. Fennessy ◽  
D. Alcorn ◽  
W. P. Anderson

To study the effects of angiotensin II on afferent and efferent arteriole diameters and on intraglomerular dimensions, angiotensin II (20 ng.kg-1.min-1) or saline vehicle was infused intravenously for 20 min into anesthetized rabbits pretreated with enalapril. Both kidneys were perfusion fixed (glutaraldehyde), and vascular casts were made of the right kidneys using methacrylate. Morphometric analysis of the left kidneys using transmission electron microscopy revealed no significant effects of angiotensin II within the glomerulus, including the degree of mesangial contraction. The diameters of the afferent and efferent arteriole casts from the right kidneys were measured at 20, 50, and 75 microns from the glomerulus by scanning electron microscopy. In the outer cortex the mean diameters of the afferent and efferent arterioles were 14.1 +/- 0.8 and 9.7 +/- 0.5 microns, respectively, in the angiotensin II-infused rabbits, significantly less than in the control (vehicle) rabbits, 17.0 +/- 0.7 microns (P less than 0.001) and 10.7 +/- 0.4 microns (P less than 0.005), respectively. Calculation of the relative changes in vascular resistance, however, indicated that the effects of angiotensin II on efferent arteriole resistance (average difference 2.4 +/- 1.2 units/microns) were significantly greater per unit length than the effects on afferent arteriole resistance (average difference 0.9 +/- 0.3 units/microns). Thus infused angiotensin II caused greater reduction in afferent arteriolar diameter than in efferent, but the calculated increase in vascular resistance per micron was greater in efferent vessels due to their smaller resting diameter.


1999 ◽  
Vol 5 (S2) ◽  
pp. 1170-1171
Author(s):  
S.M. Yu ◽  
Y.J. Yang

It has been shown that cavities or vacuoles are most evident in the posteroventral and antero ventral cochlear nucleus (PVCN & AVCN) of the gerbil. These vacuoles are reported as a neurodegenerative disorder or spongioform degeneration or a dynamic process related to the degree of auditory stimulation or microenvironmental homeostasis in the cochlear nucleus of the gerbil. Little information is avalable on the origin and formation of microcysts in the dorsal cochlear nucleus (DCN) of the gerbil. The aim of this study, was to investigate the possible formation of microcysts in the gerbil DCN after a surgical ligation of the external auditory canal by transmission electron microscopy.The mongolian gerbil, Meriones unguiculatus,had been acoustically deprived on the right side by a surgical ligation of the external auditory canal at six months old.


2019 ◽  
Vol 4 (3) ◽  
pp. 68-72
Author(s):  
Ana Maria Herrera ◽  
Godofredo García ◽  
Erick Gastellóu ◽  
Fabiola Nieto ◽  
Rafael García ◽  
...  

Hexagonal nanocrystals into Al0.2Ga0.8N and Al0.6Ga0.4N powders via pyrolysis from an organometallic compound, followed by a nitridation process in ammonia flow at 1000 °C for two hours were obtained. X-ray diffraction patterns demonstrated a shift towards greater angles to the right for the AlGaN powders with respect to GaN powders, this shift could indicate the formation of the AlGaN powders. Scanning electron microscopy micrographs showed the obtaining from semi-plates of porous appearance for the Al0.2Ga0.8N powders until well-defined plates for the Al0.6Ga0.4N powders. High resolution transmission electron microscopy micrographs demonstrated the presence of hexagonal nanocrystals into Al0.2Ga0.8N powders with an average crystal size of 10.3 nm, while that for the Al0.6Ga0.4N powders an average crystal size of 9.7 nm was observed. UV-visible spectra showed a transmittance cut-off for the Al0.2Ga0.8N powders of 3.71 eV (334.2 nm) and a transmittance cut-off of 4.53 eV (273.7 nm) for the Al0.6Ga0.4N powders.


Author(s):  
S. Siew ◽  
E. Leistikow

Atrial myxomas are the most common cardiac tumor in the adult and they account for about one half of all primary tumors of the heart. The growth of the myxoma results in the formation of an intracavitary mass which encroaches upon the capacity of the chamber leading to impedance with both the inflow and outflow, with subsequent damming back of blood and diminution of cardiac output. In addition, myxomas often extend to the atrioventricular orifice and may interfere with valve function. The tumors are accessible to surgical resection, therefore, a correct clinical diagnosis may result in a complete cure.Eight atrial myxomas were studied by means of transmission electron microscopy. Scanning electron microscopy was performed on one of these cases. Five of the patients were female and 3 were male. The age range was 40 - 77 years with an average age of 56.6. Five of the myxomas were from the left atrium and 3 from the right. All of the tumors had been attached to the atrial septum.


2007 ◽  
Vol 44 (4) ◽  
pp. 504-507 ◽  
Author(s):  
J. L. Reis ◽  
C. T. Kanamura ◽  
G. M. Machado ◽  
R. O. França ◽  
J. R. J. Borges ◽  
...  

A 12-year-old Simmental cow was presented with a moderately firm irregular whitish mass of approximately 5 cm in diameter, occupying the right orbit. Microscopically, a poorly differentiated neoplasm was observed. The immunohistochemical panel included cytokeratins, vimentin, epithelial membrane antigen, Factor VIII, CD34, Mart-1, Melan A, smooth muscle actin, desmin, chromogranin, neuron-specific enolase, S-100 protein, and MIB-1. The neoplasm was negative for all of them, with the exception of vimentin and S-100 protein. Transmission electron microscopy revealed abundant desmosomes. These findings support the diagnosis of orbital (retrobulbar) meningioma.


Development ◽  
1985 ◽  
Vol 88 (1) ◽  
pp. 1-13
Author(s):  
Kensuke E. Nakano ◽  
Harukazu Nakamura

The aim of the present study was to elucidate the origin of the striated muscle cells in the avian iris. For this purpose we adopted interspecific transplantation between quail and chick embryos because quail cells can be used as biological markers in this system. We transplanted isotopically and isochronically (6- to 7-somite stage) a fragment of a dorsal part of the quail neural anlage into a chick embryo at the level corresponding to the posterior prosencephalon and the mesencephalon on the right-hand side. In the chimaeric embryo, the iris epithelium comprised host chick cells, while most of the stromal cells of the iris on the operated side possessed the quail nuclear marker. At 19 days after the operation, the striated muscle cells had differentiated in the chimaeric embryo. These cells, as well as connective tissue cells and the Schwann cells of the iris of the chimaera, were shown to possess typical quail nuclei by light and transmission electron microscopy. From these findings, we conclude that the striated muscle cells originate from the neural crest.


2019 ◽  
Vol 9 (6) ◽  
pp. 610-615
Author(s):  
Shuo Weng ◽  
Hongchang Cai ◽  
Lihui Zhao ◽  
Songlin Zheng

The influence of microstructural variation on corrosion of SAPH440 steel induced by pre-deformation has been investigated in the corrosive solution. The microstructure observation was carried out by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The corrosion was characterized by weight loss method (WLM), open circuit potential (OCP) and potentiodynamic polarization curve (PPC) measurements. The results show that compared to the as-received specimens, the corrosion potential moves to the negative direction and corrosion current density increases after pre-deformation. The corrosion susceptibility is enhanced by the pre-deformation behavior, which is attributed to the increase in dislocation density with the increasing tensile elongation.


1999 ◽  
Vol 596 ◽  
Author(s):  
L. Sagalowicz ◽  
P. Muralt ◽  
S. Hiboux ◽  
T. Maeder ◽  
K. Brooks ◽  
...  

AbstractElectrode stability, interdiffusion, phase purity and deviation from stoichiometry at the PZT-electrode interface are key issues in PZT thin film integration. This article highlights the use of transmission electron imaging combined with energy dispersive spectroscopy (EDS) for the investigation of these phenomena. The accuracy of the EDS analysis is discussed. It will be shown that using a standard PZT sample and controlled conditions, reliable analysis can be performed.Diffusion mechanisms have been studied for Pt based electrode systems and RuO2-based electrode systems developed for direct integration onto silicon. The materials studied were composed of stacks of silicon-silicon oxide, an adhesion layer (Ti, Ta or TiOx), an electrode (Pt or RuG2) and PZT (45/55). The PZT was deposited by sol gel using the same parameters to allow for comparison of the different electrodes. Four different electrode / adhesion layer materials were compared (Pt/Ti, Pt/TiOx, Pt/Ta and RuO2 / TiO2). In the case of Pt, lead and oxygen diffusion through the electrode is observed. While the initial Ta layer transforms into a homogeneous pyrochlore phase, the Ti adhesion layer is heavily deformed. In the case of TiOx the lead is mainly incorporated at the interfaces with Pt and with SiO2. No lead diffusion to the adhesion layer is observed for the RuO2 electrode. In-situ sputtering and sol-gel deposition of PZT are also compared. The sol-gel films are close to the right stoichiometry for the perovskite while the sputtered films contained an excess of lead. No sign of second phase is found by X-ray diffraction (XRD), by EDS and by high resolution transmission electron microscopy (HRTEM) which suggests that the excess lead is accommodated in the perovskite lattice.


2001 ◽  
Vol 7 (S2) ◽  
pp. 590-591
Author(s):  
J. Shelburne ◽  
D. Howell

Immunohistochemistry (IH) has revolutionized tumor diagnosis in recent years. The antigenic/molecular information now available is extraordinarily helpful not only in clinical diagnostic work, but also in improving our understanding of the cell biology of neoplasia. As a result, there is now less need for diagnostic conventional transmission electron microscopic (CTEM) studies on neoplasms. For example, lymphomas and leukemias are now largely defined by IH and related techniques such as flow cytometry, not CTEM. A postive S-100 stain in the right setting usually obviates the need to search for melanosomes.However, CTEM is still a useful tool for surgical pathologists. One important advantage CTEM has over IH is that - like gross observations and the classic H&E section - CTEM can detect features not suspected in advance. This property of CTEM makes it particularly valuable in studying complex and unusual patients/tumors.


2020 ◽  
Vol 10 (15) ◽  
pp. 5394
Author(s):  
Duo Dong ◽  
Li Liu ◽  
Dongdong Zhu ◽  
Yang Liu ◽  
Ye Wang ◽  
...  

In this work, the Ti-48Al-2Cr alloy, solidified under different pressures and temperatures, was investigated in detail. The effect of high pressure on the microstructure and nanohardness of the Ti-48Al-2Cr alloy was investigated by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and a nanoindenter XP testing machine. The results showed that the B2 phase disappeared after high-pressure solidification. Compared with ambient pressure solidification, high pressure led to the increase of (α2 + γ) lamellar structure and the decrease of γ phase. The nanohardness of the lamellar structure was discussed based on the microstructure observation. When solidified at 5 GPa/1873 K, the hardness rose to 5.54 GPa, an increase of 60.5% compared with that solidified at ambient pressure. However, the increased holding temperature of 1973 K made the dislocation density in the lamellar structures greatly decrease, and reduced the structure’s hardness to 4.48 GPa.


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