scholarly journals Risk factors associated with ischemic heart disease occurence in acute ischemic stroke patients

2013 ◽  
Vol 157 (2) ◽  
pp. 168-171 ◽  
Author(s):  
Michal Kovacik ◽  
Stefan Madarasz ◽  
Michal Kral ◽  
Tomas Veverka ◽  
Roman Herzig ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Ischemic Heart Disease ◽  
Acute Ischemic Stroke ◽  
Ischemic Heart ◽  
Stroke Patients ◽  
Factors Associated

THE VASCULAR RISK FACTORS ASSOCIATED WITH ANTIPLATELET RESISTANCE IN ISCHEMIC STROKE PATIENTS

2020 ◽  
pp. 144-147
Author(s):  
RIZALDY TASLIM PINZON ◽  
BULAN MARCHELLIA WIJAYA
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Ischemic Heart Disease ◽  
Vascular Risk Factors ◽  
Ischemic Heart ◽  
Vascular Risk ◽  
Stroke Patients ◽  
Elderly Age ◽  
Factors Associated

Objectives: This research is to measure the prevalence rate of antiplatelet resistance in ischemic stroke patients and measure the vascular risk factors associated with antiplatelet resistance in patients with ischemic stroke. Methods and Subjects: This was a cross-sectional study with the number of respondents in this study amounted to 155 patients who all had ischemic stroke disease at Bethesda Hospital in Yogyakarta Indonesia used stroke registry to complete the data of the risk factors. VerifyNow method is used to measure the responsiveness of antiplatelet therapy. Results: Among the 155 patients with ischemic stroke, 45 were women (29%), 110 were men (71%), and the elderly (age more than 60 years old) in 81 patients. In total 155 patients with ischemic stroke, 106 of them have hypertensive, with diabetes are 19 patients, dyslipidemia is 90 patients, and ischemic heart disease in 13 patients. The prevalence of antiplatelet resistance in risk factors, for age more than 60 years, is 21 patients (25%, RR=1.06, *p=0.96), in diabetes is 7 patients (36%, RR=1.17, **p=0.74), dyslipidemia is 19 patients (21%, RR=0.68, ***p=0.24), and ischemic heart disease is four patients (30%). Among 127 patients, 22% (28 patients) had aspirin resistance, while from 42 patients, 26.2% (11 patients) were resistant to clopidogrel. Conclusion: Antiplatelet resistance is common in ischemic stroke patients. One of five patients treated with antiplatelet showed non-responsiveness. Vascular risk factors do not increase the risk of antiplatelet resistance in ischemic stroke patients.

Gender difference in risk factors associated with ischemic heart disease in Lahore

2020 ◽  
Vol 14 (2) ◽  
pp. 72-77
Author(s):  
Muhammad Salman Tariq ◽  
Iram Manzoor ◽  
Qurat Ul Ain Zulfi ◽  
Naeem Hussain ◽  
Nimra Saleem ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Gender Difference ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Public Health Issue ◽  
Stressful Event ◽  
Female Population ◽  
High Tendency ◽  
Factors Associated

Background: Ischemic heart disease (IHD) is one of the leading causes of mortality in Pakistan. With advancement in research, multiple causes have contributed in development of web of causation of this public health issue. The objective of this study was to assess gender differences in risk factors associated with ischemic heart disease in patients presenting at the biggest cardiology hospital of Lahore. Patients and methods: A comparative cross-sectional study was carried out in Punjab Institute of Cardiology, Lahore from January to August, 2018 on a sample of 296 diagnosed patients of IHD, through non-probability consecutive sampling technique. Data was collected on pretested questionnaire. The data was analyzed using SPSS version 22. Chi-Square test of significance was applied and a p-value ≤0.05 was considered statistically significant. Results: The mean age of participants was 45±12 years with predominance of male patients (71.3%). Frequency of risk factors for IHD included increase body mass index (83.8%), hypertension (61%), insufficient physical activity (43%), diabetes (38.5%) and smoking (23%). Increase serum cholesterol was reported in 95% and triglycerides in 99% of the participants. Gender difference was significant with females residing in urban population (p=0.054) and exercise routine (p=0.034). Males showed high tendency of IHD with smoking pattern (p<0.001) contrary to presence of diabetes in females (p=0.05), hypertension (p=0.054), BMI (p=0.0379) and stressful event in life (p=0.002). Males showed regular intake of medicines (p =0.045) after diagnosis as compared to female population. Conclusion: There is more frequency of ischemic heart disease in males as compared to females. Significant association was observed with residence in urban area, presence of diabetes, hypertension, high BMI and stressful event in life in occurrence of ischemic heart disease in female population.

scholarly journals Behavioural risk factors associated with ischemic heart disease among population attending selected cardiac hospitals of Kathmandu, Nepal

2018 ◽  
Vol 15 (2) ◽  
pp. 25-32
Author(s):  
Sangita Shrestha ◽  
Shova Laxmi Bajracharya
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Heart Diseases ◽  
Significant Risk ◽  
Sampling Technique ◽  
Ischemic Heart ◽  
Institute Of Medicine ◽  
Waist To Hip Ratio ◽  
Factors Associated

Background and Aims: Ischemic Heart Disease (IHD) is the number one cause of morbidity and mortality among the in-patient of different cardiac hospital of developing countries like Nepal. The prevalence of IHD is high with significant associated risk factors that include tobacco use, history of hypertension, family history and age. Though IHD can cause life-threatening conditions like myocardial infarction, yet it is preventable disease. The objective of the study was to study the risk factors associated with ischemic heart diseases among population attending selected cardiac hospitals of Kathmandu.Methods: Hospital- based pair matched case-control was conducted among the patients with IHD at Manmohan Cardiothoracic Vascular and Transplant Centre (MCTVC) and Shahid Gangalal National Heart Center (SGNHC). Non- random purposive sampling technique was applied and sample size was calculated as 105 (35 cases and 70 controls). Case and control were matched with age (Å} 2 years) and sex from the same hospitals. Ethical approval was taken from Institutional review board, Institute of medicine. Informed consent was obtained prior to information collection, after explaining about the purpose of the study to the entire participants. Only interested participants were included in the study. Confidentiality of the subject was ensured by collecting data in separate private room. Univariate associations between the risk factors and IHD under study was assessed by applying Chi-Square test and Fisher’s exact test and expressed as odds ratios with 95% confidence intervals. To assess the strength of association, the odds ratio was calculated.Results: 88.6% cases and 90% controls participants were of age 41 years and above and IHD was more common in male (60%) than female (40%). The participants who were not doing work-related moderate-intense activity are twice more likely to have IHD compared to controls (OR=2.276, p=0.049), similarly, hypertensive are two times (OR=2.276, p=0.049), obese are more than two times (OR=2.44, p=0.045), and participants with high waist to hip ratio are almost three times more likely to suffer from IHD (OR=2.88, p=0.013).Conclusions: The current smoking, physical inactivity, hypertension and waist to hip ratio tend to be the significant risk factors of IHD. Minimizing exposure to the identified risk factors can prevent burden of complex and expensive IHD treatment.

Correlations Between Acute Ischemic Stroke And Its Associated Cardiovascular Diseases

2014 ◽  
Vol 7 (2) ◽  
pp. 105-109
Author(s):  
Daniela Y. Arabadzhieva ◽  
Ara G. Kaprelyan ◽  
Zdravko D. Slavov ◽  
Zhaneta T. Georgieva ◽  
Aleksandra Zh. Tsukeva
Keyword(s):  
Myocardial Infarction ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Cardiovascular Diseases ◽  
Angina Pectoris ◽  
Ischemic Heart Disease ◽  
Acute Ischemic Stroke ◽  
Coronary Atherosclerosis ◽  
Ischemic Heart ◽  
Effort Angina

Summary The objective of this study was to analyze the association between some cardiovascular diseases and acute ischemic stroke. A total of 258 acute ischemic stroke patients (mean age 70.59±7.22 years) were examined. The presence of eight cardiovascular diseases and pathological conditions was analyzed: arterial hypertension, hypertensive heart, atrial fibrillation, myocardial infarction, ischemic heart disease, effort angina pectoris, coronary atherosclerosis, and heart failure. Data were statistically processed by variation and correlation analysis. Most male and female patients presented with four accompanying cardiovascular diseases (27 or 20.93% and 31 or 24.03% of the cases, respectively). There were two groups of four variables each - with a relatively strong and a moderate, as well as with a weak correlation (r<0.4), to the presence of acute ischemic stroke in the corresponding patients. Ischemic heart disease was strongly associated with effort angina pectoris (r=0.667) and to a lesser extent - with coronary atherosclerosis (r=0.470), whereas myocardial infarction was associated with coronary atherosclerosis (r=0.604) and ischemic heart disease (r=0.378), respectively. Arterial hypertension was moderately related to hypertensive heart (r=0.300). In conclusion, there were relatively close associations between acute ischemic stroke and these heart diseases. These patients should strictly and regularly be followed up by general practitioners.

scholarly journals Cholesterol reducer and thrombolytic therapy in acute ischemic stroke patients

2020 ◽  
Author(s):  
Nicolas Poupore ◽  
Dan Strat ◽  
Tristan Mackey ◽  
Katherine Brown ◽  
Ashley Snell ◽  
...  
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Demographic Data ◽  
Clinical Risk Factors ◽  
Stroke Patients ◽  
Medication History ◽  
Factors Associated ◽  
Clinical Risk

Abstract Background Specific clinical risk factors may contribute to worsening or improving neurological functions in an acute ischemic stroke (AIS) patient pre-treated with a cholesterol reducer with a subsequent recombinant tissue plasminogen activator (rtPA) treatment. We investigated clinical risk factors associated with good or poor presenting neurological symptoms in ischemic stroke patients with prior cholesterol reducer use, specifically a statin and rtPA therapy. Methods We retrospectively analyzed baseline clinical and demographic data of 630 patients with AIS taking cholesterol reducers prior to rtPA treatment from January 2010 to June 2016 in a regional stroke center. Progressing (NIHSS ≤ 7) or worsening (NIHSS > 7) scores for neurologic improvement determined measures for treatment outcome. Multivariate logistic regression models identified demographic and clinical factors associated with worsening or progressing neurologic functions. Results Adjusted multivariate analysis showed that in an ischemic stroke population with a combined rtPA and cholesterol reducer medication history, increasing age (OR = 1.032, 95% CI, 1.015-1.048, P < 0.001) and atrial fibrillation (OR = 1.859, 95% CI, 1.098-3.149, P = 0.021) demonstrated a likely association with worsening neurologic functions, while direct admission (OR = 0.411, 95% CI, 0.246-0.686, P = 0.001) and being Caucasian (OR = 0.496, 95% CI, 0.297-0.827, P = 0.007) showed an association with improving or progressing neurologic functions. Conclusion A prior cholesterol reducer, namely a statin, plus rtPA combination may be associated with worsening neurological function for elderly AIS patients with atrial fibrillation, while Caucasians directly admitted to a neurology unit are more likely to show an association with progress or improvements in neurologic functions.

scholarly journals Myocardial Infarction And Ischemic Heart Disease In Patients With Acute Ischemic Stroke

2015 ◽  
Vol 8 (1) ◽  
pp. 26-29
Author(s):  
Daniela Y. Arabadzhieva ◽  
Zhaneta T. Georgieva ◽  
Ara G. Kaprelyan ◽  
Zdravko D. Slavov
Keyword(s):  
Myocardial Infarction ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Ischemic Heart Disease ◽  
Acute Ischemic Stroke ◽  
Ischemic Heart ◽  
University Hospital ◽  
Regular Control ◽  
Healthy Life Style ◽  
The One

SummaryThe aim of the investigation was to analyze the correlation between myocardial infarction and ischemic heart disease, on the one hand, and acute ischemic stroke (AIS), on the other hand. We studied 258 AIS patients (mean age 70.9±7.22 years, range 49-92 years) hospitalized in 2007-2013 in the First Clinic of Neurology, St. Marina University Hospital of Varna. The diagnosis of acute ischemic stroke was confirmed by Doppler sonography and computed tomography of the cerebral circulation. Data were statistically processed by variation and correlation analysis. Our results proved a relatively strong correlation between effort angina pectoris and ischemic heart disease (Pearson's coefficient: r=0.643) as well as a weak correlation between ischemic heart disease and myocardial infarction (Pearson's coefficient: r=0.243) among acute ischemic stroke patients. The well-known risk factors for these cardiovascular diseases such as obesity, tobacco smoking, low physical activity and alcohol abuse were common among the patients with acute ischemic stroke, too. In conclusion, both myocardial infarction and ischemic heart disease are strongly associated with the development of acute ischemic stroke. Such patients require strict and regular control by general practitioners. They should observe an appropriate diet and adhere to a healthy life-style.

scholarly journals Prevalence and Risk Factors of Stroke in Bangladesh: A Nationwide Population-Based Survey

2021 ◽  
Author(s):  
Md Badrul Alam Mondal ◽  
A T M Hasibul Hasan ◽  
Nushrat Khan ◽  
Quazi Deen Mohammad
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Population Based ◽  
Ischemic Heart ◽  
List Type ◽  
Stroke Patients ◽  
Stroke Prevalence ◽  
Common Risk Factors ◽  
Suspected Stroke

AbstractBackgroundThis community survey was conducted to estimate the prevalence of stroke and its associated common risk factors among the Bangladeshi population.MethodsThis was a population-based cross-sectional study, carried out in 8 administrative divisions and 64 districts to estimate the prevalence of stroke throughout the country. The study adopted a two-stage cluster random sampling approach. The calculated sample size was 25,287. A semi-structured questionnaire was used to identify suspected stroke patients who were subsequently confirmed by consultant neurologists.ResultIn the first stage, Interviewers identified 561 respondents as suspected stroke in 64 districts. Of the 25,287 respondents, 54.9% were male. The mean age was 39.9 years. In the second stage of the study; among all the respondents, 288 were confirmed as stroke patients which provided a prevalence of 11.39 per 1000 population. The highest stroke prevalence (14.71 per thousand) was found in the Mymensingh division and the lowest (7.62 per thousand) found in the Rajshahi division. It was 30.10 per thousand in the age group of more than 60 years. The prevalence of stroke among males was twice that of females (13.62 versus 8.68 per thousand). The prevalence was slightly higher in rural areas (11.85 versus 11.07). Out of a total of 288 cases, 79.7% (213) patients had an ischemic stroke, 15.7% (42) had hemorrhagic, and 4.6% (12) were diagnosed as subarachnoid hemorrhage. The majority of the stroke patients had hypertension (79.2%), followed by dyslipidemia (38.9%), tobacco use in any form (37.2%), diabetes (28.8%), ischemic heart disease (20.1%).ConclusionWe have found a stroke prevalence of 11.39 per 1000 population, the highest being in the Mymensingh division. The prevalence was much higher in the elderly and male population. More than three fourth had an ischemic stroke. Hypertension, dyslipidemia, tobacco use, diabetes, ischemic heart disease are the most common risk factors observed among stroke patients.Summary BoxAlready Known:▪The prevalence of stroke in Bangladesh was found to be 3 per thousand.▪Hypertension, diabetes, dyslipidemia, smoking, and ischemic heart disease were common risk factors.New Findings:▪This is the first-ever nationwide survey in Bangladesh that revealed a stroke prevalence of 11.39 per thousand.▪There was a wide regional variation of stroke prevalence.▪The prevalence was twice among males.Impact of the study result:▪The study result will help the policymakers in deciding what to do for which regions of this country to handle the stroke burden.▪It will also help the clinicians to identify common risk factors among stroke patients.

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