Exploration of Elephant Foot Yam (Amorphophallus paeoniifolius) Starch: An Alternative Natural Disintegrant for Pharmaceutical Application

An investigation has been made to characterize the local accessions of Elephant foot yam collected from thirteen aroid growing districts and in-depth study on genetic variability, correlation and path coefficient for plant height, petiole length, petiole breadth, leaf area index, corm length, corm breadth, corm weight, cormel number, cormel length, cormel breadth, cormel weight and yield per plant has also been carried out. Genotypic variances and coefficient of variation for most of the characters were remarkably higher than their corresponding environmental variances, which also indicate the existence of variation in genotypic origin. High heritability with high genetic advance in percentage of mean was also observed for all characters. In the correlation study plant height, leaf area index, corm length, corm breadth, corm weight, cormel number, cormel length, cormel breath showed positive correlation with yield per plant in genotypic and phenotypic level. Leaf area index, cormel number in phenotypically and cormel number in genotypic level showed relatively high positive direct effect on yield per plant.Keywords: Amorphophallus; Genetic variability; Correlation; Path coefficient.© 2013 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi: http://dx.doi.org/10.3329/jsr.v5i2.13853 J. Sci. Res. 5 (2), 371-381 (2013)

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Recent Applications of Nanoemulsion Based Drug Delivery System: A Review

Research Journal of Pharmacy and Technology ◽

10.52711/0974-360x.2021.00502 ◽

2021 ◽

pp. 2852-2858

Author(s):

Asif Eqbal ◽

Vaseem Ahamad Ansari ◽

Abdul Hafeez ◽

Farogh Ahsan ◽

Mohd Imran ◽

...

Keyword(s):

Drug Delivery ◽

Drug Delivery System ◽

Delivery System ◽

Transdermal Drug Delivery ◽

Therapeutic Agents ◽

Topical Drug Delivery ◽

Transdermal Drug Delivery System ◽

Small Droplet ◽

Pharmaceutical Application ◽

System A

Nanoemulsions are drug transporters for the delivery of therapeutic agents. They possess the small droplet size having the range of 20×10-9-200×10-9m. The main purpose of using Nanoemulsion is to enhance the drug bio- availability of transdermal drug delivery system. With the help of phase diagram, we can select the components of nanoemulsion depending upon formulas ratio of oil phase, surfactant/co-surfactant and water phase. Nanoemulsion directly used as a topical drug delivery in skin organs. The most useable pharmaceutical application has been developed till date to provide systemic effects to penetrating the full thickness of skin organ layer nanoemulsions can be administered through variety of routes such as percutaneous, perioral, topical, transdermal, ocular and parental administration of medicaments. Nanoemulsions are transparent and slightly opalescent. Nanoemulsion can be prepared through various methods. Nanoemulsions are transparent and slightly opalescent. Factor affecting nanoemulsions are surfactant, viscosity, lipophilic, drug content, pH, concentration of each component, and methodology of formulation. It is unfeasible to test all factors at the various levels. Design of formulation when it comes to experimental design it gives an excellent approach through reducing the time and money.

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Nanomaterials for the delivery of Herbal Bioactive Compounds

Current Nanoscience ◽

10.2174/1573413717666211004090341 ◽

2021 ◽

Vol 17 ◽

Author(s):

Shadma Wahab ◽

Md. Parwez Ahmad ◽

Arshad Hussain ◽

Shaik Fayazuddin Abdul Qadir

Keyword(s):

Drug Delivery ◽

Bioactive Compounds ◽

Targeted Drug Delivery ◽

Herbal Medicines ◽

Herbal Drugs ◽

Herbal Extracts ◽

Significant Component ◽

Pharmaceutical Application ◽

Low Solubility ◽

Insight Into

: Nanotechnology is a multidisciplinary domain that involves overlapping of areas such as nonanomaterials, nanoelectronics, and nanobiotechnology. Herbal medicine is a significant component of traditional medicine and has been a treatment part of many diseases. Asian peoples are using these herbal medicines for decades. Still, herbal extracts' therapeutic efficacy and pharmaceutical application are associated with many factors such as poor bioavailability, low solubility, permeability, and lack of targeting potential. In the present work, we have reviewed thriving strategies for the targeted drug delivery of phytoconstituents and critically explain the most recent progressions on emerging novel nanophytomedicine-based materials as herbal medicines carriers. Nanotechnology-based clinical trial studies targeting herbal bioactive compounds were discussed. Advancements in nanotechnology-based drug delivery systems intended to enhance cellular uptake, improved pharmacokinetics and effectiveness of herbal drugs have facilitated the powerful targeting of specific agents against diseases. This review provides insight into current progress and future opportunities for nanomedicines as potential curative targets for the delivery of herbal bioactive compounds. This information could be used as platforms for the future expansion of multi-functional nano constructs for the advanced detection of diseases and functional drug delivery of phytoconstituents.

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Statistical optimization of elephant foot yam (Amorphophallus paeoniifolius) lacto-pickle for maximal yield of lactic acid

LWT ◽

10.1016/j.lwt.2017.09.010 ◽

2018 ◽

Vol 87 ◽

pp. 342-350 ◽

Cited By ~ 6

Author(s):

Sudhanshu S. Behera ◽

Smita H. Panda ◽

Sonali Mohapatra ◽

Awanish Kumar

Keyword(s):

Lactic Acid ◽

Statistical Optimization ◽

Maximal Yield ◽

Elephant Foot Yam

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Resistant Starch Contents of Native and Heat-Moisture Treated Jackfruit Seed Starch

The Scientific World JOURNAL ◽

10.1155/2015/519854 ◽

2015 ◽

Vol 2015 ◽

pp. 1-10 ◽

Cited By ~ 9

Author(s):

Ornanong S. Kittipongpatana ◽

Nisit Kittipongpatana

Keyword(s):

Resistant Starch ◽

Temperature Treatment ◽

Ordered Structure ◽

High Moisture ◽

Pharmaceutical Application ◽

Treatment Conditions ◽

Moisture Treatment ◽

Ft Ir ◽

Commercial Source ◽

Significant Change

Native jackfruit seed starch (JFS) contains 30% w/w type II resistant starch (RS2) and can potentially be developed as a new commercial source of RS for food and pharmaceutical application. Heat-moisture treatment (HMT) was explored as a mean to increase RS content of native JFS. The effect of the conditions was tested at varied moisture contents (MC), temperatures, and times. Moisture levels of 20–25%, together with temperatures 80–110°C, generally resulted in increases of RS amount. The highest amount of RS (52.2%) was achieved under treatment conditions of 25% MC and 80°C, for 16 h (JF-25-80-16). FT-IR peak ratio at 1047/1022 cm−1suggested increases in ordered structure in several HMT-JFS samples with increased RS. SEM showed no significant change in the granule appearance, except at high moisture/temperature treatment. XRD revealed no significant change in peaks intensities, suggesting the crystallinity within the granule was mostly retained. DSC showed increases inTgand, in most cases,ΔT, as the MC was increased in the samples. Slight but significant decreases inΔHwere observed in samples with low RS, indicating that a combination of high moisture and temperature might cause partial gelatinization. HMT-JFS with higher RS exhibited less swelling, while the solubility remained mostly unchanged.

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