scholarly journals Synthesis of New Mixed-Ligand Complexes of Molybdenum (IV) and Tungsten(IV): Characterization, Structure, Thermal and Anti-microbial Studies

2019 ◽  
Vol 11 (1) ◽  
pp. 43
Author(s):  
Festus Sunday Fabiyi ◽  
Friday O. Nwosu
Keyword(s):  
1H Nmr ◽  
Antimicrobial Activities ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes ◽  
Spectral Studies ◽  
Mass Spectral ◽  
Bacteria And Fungi ◽  
And Tungsten

Six new mixed-ligand complexes of Mo(IV) and W(IV) ions have been prepared and characterized. The three new complexes of Mo(IV) ions have the molecular formulae MoC12N2O5H18, MoC15N2O5H22 and MoC14N2O6H19 , while the W(II) ions are WC12N2O5H18, WC15N2O5H22 and WC14N2O6H19. The structures of the complexes were deduced from their ir, 1H nmr, and mass spectral studies. All the complexes were found to exhibit octahedral structures. Their antimicrobial activities against some bacteria and fungi species were found to be moderate.

scholarly journals Synthesis, Characterization and Antimicrobial Activity of Mixed Schiff Base Ligand Complexes of Co(II), Ni(II), Cu(II) and Zn(II)

2011 ◽  
Vol 8 (3) ◽  
pp. 1258-1263 ◽  
Author(s):  
A. K. Mapari ◽  
M. S. Hate ◽  
K. V. Mangaonkar
Keyword(s):  
Antimicrobial Activity ◽  
Thermogravimetric Analysis ◽  
Schiff Bases ◽  
Free Ligand ◽  
Antimicrobial Activities ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes ◽  
Azomethine Nitrogen ◽  
Diffusion Method ◽  
Spectral Studies

The mixed ligand complexes of Co(II), Ni(II), Cu(II) and Zn(II) with Schiff basesN-(2-hydroxy-1-naphthylidene)-4-methylaniline (L1H) andN-(2-hydroxybenzylidene)-2,3-dimethylaniline (L2H) have been synthesized and characterized. The resulting complexes were characterized by elemental analysis, thermogravimetric analysis, magnetic moment measurements, conductivity measurements,1H NMR, IR, UV-visible and ESR spectral studies. The Schiff bases acts as bidentate monobasic ligands, coordinating through deprotonated phenolic oxygen and azomethine nitrogen atoms. The complexes are non-electrolytic in DMSO. The presence of the two coordinated water molecules in these complexes was indicated by IR spectra and thermogravimetric analysis of the complexes. From the analytical and spectral data the stoichiometry of these complexes have been found to be [M(L1)(L2)(H2O)2] {where M = Co(II) , Ni(II), Cu(II) and Zn(II)}. It is found that Co(II), Ni(II), Cu(II) and Zn(II) complexes exhibited octahedral geometry. The antimicrobial activities of ligands and their mixed ligand complexes were screened by disc diffusion method. It is found that the metal complexes have higher antimicrobial activity than the free ligand.

scholarly journals Synthesis and Antimicrobial Studies of Novel N-Glycosyl Hydrazino Carbothioamide

2020 ◽  
Vol 33 (1) ◽  
pp. 127-131
Author(s):  
Riddhi A. Nayak ◽  
Anvita D. Mangte
Keyword(s):  
Antimicrobial Activity ◽  
1H Nmr ◽  
Medicinal Chemistry ◽  
Antimicrobial Activities ◽  
Spectral Studies ◽  
Mass Spectral ◽  
E Coli ◽  
Antimicrobial Studies ◽  
Antimicrobial Evaluation

In view of applications of N-glycosylated compounds in medicinal chemistry and in many other ways, herein the synthesis of novel N-glycosyl hydrazino carbothioamides is reported. New N-glycosyl hydrazino carbothioamides were synthesized by the condensation of per-O-acetyl glycosyl isothiocyanate with different aromatic hydrazides. The newly synthesized compounds were characterized by using the IR, 1H NMR and mass spectral studies. Antimicrobial evaluation of the synthesized N-glycosyl hydrazino carbothioamide was also examined. Antimicrobial activities of the synthesized compound were evaluated against bacteria E. coli, P. aeruginosa, S. aureus, S. pyogenus and fungi C. albicans, A. niger and A. clavatus. All the N-glycosyl hydrazino carbothioamides exhibit promising antimicrobial activity.

scholarly journals Structural elucidation, thermal studies and antimicrobial screening of mixed ligans complexes of 4-benzylimino-2,3-dimethyl-1-phenylpyrazal-5-one and L-Lysine

2021 ◽  
Vol 12 (2) ◽  
pp. 96-103
Author(s):  
E.T. Omotade ◽  
A.P. Oviawe
Keyword(s):  
Thermal Stability ◽  
Antimicrobial Activity ◽  
Thermal Studies ◽  
Octahedral Geometry ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes ◽  
Spectral Studies ◽  
Conductivity Measurements ◽  
Ft Ir ◽  
Bacteria And Fungi

The mixed ligand complexes involving Fe(II), Co(II) and Ni(II) ions, Schiff base 4 phenylpyrazal-5-one (L1) and L-lysine (Lys) were synthesized. The complexes were characterized on the basis of their elemental analysis, conductivity measurements, FT-IR, MS,1H-NMR and 13C-NMR spectral studies. All the synthesized complexes were subjected to simultaneous thermogravimetric analysis to study their decomposition mechanism and thermal stability. The mixed ligand complexes were screened against some strains of bacteria and fungi to study their antimicrobial activity. The complexes were found to be non-electrolytes and possessed octahedral geometry. The results showed that the metal complexes possessed better antimicrobial activity than the free ligands.

scholarly journals Syntheses and Studies of 8-Substituted-2-(2-Chlorophenyl/3-chlorophenyl)- 4-(4-hydroxyphenyl/phenyl)-2,3/2,5-dihydro-1,5-benzothiazepines

2021 ◽  
Vol 33 (11) ◽  
pp. 2653-2656
Author(s):  
Seema Pant ◽  
Pushpa Godwal ◽  
Kumari Sanju
Keyword(s):  
Candida Albicans ◽  
1H Nmr ◽  
Biological Activities ◽  
Antimicrobial Activities ◽  
Spectral Studies ◽  
Schmidt Reaction ◽  
Mass Spectral ◽  
Unsaturated Ketones ◽  
Michael Condensation ◽  
Paper Disc

Syntheses of novel twelve 8-substituted-2-(2-chlorophenyl/3-chlorophenyl)-4-(4-hydroxyphenyl/ phenyl)-2,3/2,5-dihydro-1,5-benzothiazepines have been carried out by the reactions of 5-substituted 2-aminobenzenethiols, the substituents being fluoro, chloro, bromo, methyl, methoxy or ethoxy with α,β-unsaturated ketones, 3-(2-chlorophenyl)-1-(4-hydroxyphenyl)-2-propenone or 3-(3-chloro-phenyl)-1-phenyl-2-propenone in dry ethanol in acidic medium in quest for the synthesis of 1,5-benzothiazepine compounds, which may have interesting biological activities. The precursors, substituted α,β-unsaturated ketones were obtained by employing the Claisen-Schmidt reaction; and the final products, obtained by Michael condensation, were characterized by analytical and spectral data comprising IR, 1H NMR and mass spectral studies. Two different series, 2,3-dihydro and 2,5-dihydro series of the final compounds were obtained depending on the substituents present, as indicated by the 1H NMR spectra. The newly synthesized compounds were studied for their antimicrobial activities against Staphylococcus aureus, Escherichia coli and Candida albicans taking imipenem, vancomycin and fluconazole as reference standards using Paper Disc method. Five of the compounds tested showed good antifungal activity against Candida albicans at the concentration of 200 μg/disc.

scholarly journals Microwave Irradiative Synthesis of Triazine Substituted Pyrazoles and Study of Antitubercular and Antimicrobial Activities

2019 ◽  
Vol 31 (5) ◽  
pp. 1087-1090 ◽  
Author(s):  
Pradip P. Deohate ◽  
Roshani S. Mulani
Keyword(s):  
Antimicrobial Activity ◽  
Elemental Analysis ◽  
Structural Investigation ◽  
Antimicrobial Activities ◽  
Spectral Studies ◽  
Gram Negative ◽  
Mass Spectral ◽  
The Relationship ◽  
Substituted Pyrazoles ◽  
Structure And Activity

Microwave irradiative synthesis of triazine substituted pyrazoles i.e. (4-benzylideneamino-6-methyl-[1,3,5]-triazin-2-yl)-(5-methyl-2-substituted benzoyl/isonicotinoyl/cinnamoyl-pyrazol-3-yl)-amines have been achieved by the cyclocondensation of N-(4-benzylideneamino-6-methyl-[1,3,5]-triazin-2-yl)-3-oxo butyramide with substituted acid hydrazides. Synthesis of required butyramide was done by reacting 2,4-diamino-6-methyl-[1,3,5]-triazine with benzaldehyde and then condensing the product with ethyl acetoacetate. Structural investigation of synthesized compounds has been done by chemical transformation, elemental analysis and IR, 1H NMR, mass spectral studies. Study of antitubercular and antimicrobial activity of title compounds against some selected Gram-positive and Gram-negative microorganisms was performed to establish the relationship between structure and activity of compound.

scholarly journals Synthesis and Spectroscopic Studies of New Palladium(II) Complexes of N-hydroxymethyl Saccharin (Sac-CH2OH) and Amines or Diaminas Ligands

2019 ◽  
Vol 35 (1) ◽  
pp. 186-192 ◽  
Author(s):  
Ahmed S. Al-Janabi ◽  
Adnan A. Al-Dulaimi ◽  
Hayfa M. Gergees ◽  
Mohammed H. Saleh
Keyword(s):  
1H Nmr ◽  
Nmr Spectra ◽  
Spectroscopic Studies ◽  
Mixed Ligand ◽  
1H Nmr Spectra ◽  
Ethylene Diamine ◽  
Mixed Ligand Complexes ◽  
Conductivity Measurements

Treatment of the chelated palladium(II) complex, trans-[Pd(K2-Sac-CH2O)2].2H2O with one mole equivalent of the diammines (L-L), L-L = 2,2'-bipyridine (bipy),. ethylene diamine (en), 1,10-phenanthroline (phen), or N,N-dimethyl ethylene diammine (dmen) in EtOH solvent afforded mixed ligand complexes of the type [Pd(K1-Sac-CH2O)2(L-L)] in 82-93% yield. While treatment of trans-[Pd(K2-Sac-CH2O)2].2H2O with two mole equivalents of the monoamines (L), L=pyridine (py), 3-methylpyridine (3-mpy) or 3-aminopyridine (3-apy) in EtOH solvent gave trans-[Pd(K1-Sac-CH2O)2(L)2] complexes in 86-89% yield The prepared complexes were characterized by elemental CHN analysis, .conductivity measurements,. infrared and 1H nmr spectra.

scholarly journals Antimicrobial activities of some mixed ligands adducts of benzoylacetone and salicylaldehyde

2018 ◽  
Vol 11 (1) ◽  
pp. 174-178
Author(s):  
Muhammad Saleh Salga ◽  
Sani Sabo
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Candida Albicans ◽  
Antimicrobial Activities ◽  
Mixed Ligand ◽  
Mixed Ligand Complexes ◽  
Metal Chlorides ◽  
Antimicrobial Studies ◽  
Mixed Ligands

A series of four mixed ligand complexes synthesized by reacting benzoylacetone and salicylaldehyde with different metal chlorides in ethanolic medium, were tested for their antimicrobial studies and indicated that the compounds are active against microorganisms used (Escherichia coli, Staphylococcus aureus, and Candida albicans) when compared with the activity of the reference or standard drugs (Erythromycin and Suptrin).Keywords: Antimicrobial, Synthesis, Ligands, Complexes

f-f spectral studies of holmium(III) complexes

1983 ◽  
Vol 36 (4) ◽  
pp. 695 ◽  
Author(s):  
K Iftikhar ◽  
N Ahmad
Keyword(s):  
Coordination Number ◽  
Oscillator Strength ◽  
Magnetic Moment ◽  
Visible Region ◽  
Mixed Ligand ◽  
Oscillator Strengths ◽  
Mixed Ligand Complexes ◽  
Spectral Studies ◽  
Nitrogen Donors ◽  
Covalency Parameters

Holmium(III) mixed-ligand complexes containing ligands having oxygen and nitrogen donors have been spectrophotometrically investigated. The observed spectra in the visible region have been analysed to calculate covalency parameters (β, b� and δ), oscillator strengths and Judd-Ofelt parameters. The degree of covalency in the complexes increases with increase in coordination number. The hypersensitivity is correlated with the degree of covalency and number of coordinated ligands. The higher values of covalency parameters, oscillator strength and magnetic moment in the ten-coordinate HoIII is taken as evidence of participation of f-orbitals in bonding.

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