scholarly journals Histopatological Effect Characteristics of Various Biomaterials and Monomers Used in Polymeric Biomaterial Production

Author(s):  
Serpil Unver ◽  
Dursun Saraydi

2017 ◽  
Vol 8 (35) ◽  
pp. 5415-5426 ◽  
Author(s):  
Yuanyuan Ju ◽  
Mingming Zhang ◽  
Hanying Zhao

Poly(ε-caprolactone) with pendant glutathione or l-carnosine was synthesized by a combination of ring-opening copolymerization, click chemistry and thiol-disulfide exchange reaction, and the self-assemblies of the polymers were investigated.



Author(s):  
Nnamdi C. Iheaturu ◽  
Ihuoma V. Diwe ◽  
Alma Tamunonengiofori Banigo ◽  
Oluyemi O. Daramola ◽  
Emmanuel Rotimi Sadiku


Author(s):  
Guvendiren Murat ◽  
Dube Koustubh ◽  
Molde Joseph ◽  
Kohn Joachim


Polymers ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 2094 ◽  
Author(s):  
Rushita Shah ◽  
Pavel Stodulka ◽  
Katerina Skopalova ◽  
Petr Saha

The application of polymeric biomaterial scaffolds utilizing crosslinking strategy has become an effective approach in these days. In the present study, the development and characterization of collagen–chitosan hydrogel film has been reported on using dual crosslinking agent’s, i.e., tannic acid and genipin simultaneously. Incorporation of genipin imparts a greenish-blue color to the polymeric film. The effect of dual crosslinking and their successful interaction within the matrix was evaluated by infrared analysis spectroscopy. The porosity of the film was examined using scanning electron microscopy (SEM). Results of TGA determine the intermediate thermal degradation. Further, the crosslinking phenomenon has found primary impact on the strength of the films. Enzymatic degradation for the films was performed with lysozyme and lipase. The cell adhesion and proliferation was also accomplished using mouse embryonic cell lines wherein the cells cultured on the dual crosslinked film. The thriving utilization of such dual crosslinked polymeric film finds their applications in ophthalmology especially as an implant for temporary injured cornea and skin tissue regeneration.



2017 ◽  
Vol 14 (130) ◽  
pp. 20161028 ◽  
Author(s):  
Anne-Christin Schöne ◽  
Toralf Roch ◽  
Burkhard Schulz ◽  
Andreas Lendlein

Polymeric biomaterials are of specific relevance in medical and pharmaceutical applications due to their wide range of tailorable properties and functionalities. The knowledge about interactions of biomaterials with their biological environment is of crucial importance for developing highly sophisticated medical devices. To achieve optimal in vivo performance, a description at the molecular level is required to gain better understanding about the surface of synthetic materials for tailoring their properties. This is still challenging and requires the comprehensive characterization of morphological structures, polymer chain arrangements and degradation behaviour. The review discusses selected aspects for evaluating polymeric biomaterial–environment interfaces by Langmuir monolayer methods as powerful techniques for studying interfacial properties, such as morphological and degradation processes. The combination of spectroscopic, microscopic and scattering methods with the Langmuir techniques adapted to polymers can substantially improve the understanding of their in vivo behaviour.



Author(s):  
Chisako MIZUMOTO ◽  
Kumiko YOKOTA ◽  
Chiaki HIWA ◽  
Yoshikazu NAKAI


2007 ◽  
Vol 342-343 ◽  
pp. 293-296 ◽  
Author(s):  
Wan Jin Cho ◽  
Jun Ho Kim ◽  
Se Heang Oh ◽  
Jin Ho Lee

Electrospinning is a fabrication process that can produce highly porous nano-scale fiber-based matrices using an electrostatically driven jet of polymer solution. This method represents an attractive approach for polymeric biomaterial processing which provides the membrane structure that may retain mechanical strengths, flexibility, and high surface area. In this study, we prepared a guided bone regeneration (GBR) membrane with selective permeability, hydrophilicity, good mechanical strength and adhesiveness with bone using polycaprolactone (PCL) and Tween 80 by the electrospinning method. The prepared PCL and PCL/Tween 80 electrospun sheets were characterized via morphology observation, mechanical property, water absorbability, and model nutrient permeability. It was observed that the PCL/Tween 80 (3 wt%) electrospun sheet have an effective permeation of nutrients as well as the good mechanical strength to maintain a secluded space for the bone regeneration. From the results, the hydrophilized PCL/Tween 80 (3 wt%) electrospun sheet seem to be a good candidate as a GBR membrane.



2021 ◽  
Author(s):  
Guzmán Carissimi ◽  
Mercedes G. Montalbán ◽  
Marta G. Fuster ◽  
Gloria Víllora

The use of nanoparticles in biomedical fields is a very promising scientific area and has aroused the interest of researchers in the search for new biodegradable, biocompatible and non-toxic materials. This chapter is based on the features of the biopolymer silk fibroin and its applications in nanomedicine. Silk fibroin, obtained from the Bombyx mori silkworm, is a natural polymeric biomaterial whose main features are its amphiphilic chemistry, biocompatibility, biodegradability, excellent mechanical properties in various material formats, and processing flexibility. All of these properties make silk fibroin a useful candidate to act as nanocarrier. In this chapter, the structure of silk fibroin, its biocompatibility and degradability are reviewed. In addition, an intensive review on the silk fibroin nanoparticle synthesis methods is also presented. Finally, the application of the silk fibroin nanoparticles for drug delivery acting as nanocarriers is detailed.



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