scholarly journals Ginseng in Hair Growth and Viability

2021 ◽  
Author(s):  
Mirecki-Garrido Mercedes ◽  
Santana-Farré Ruymán ◽  
Guedes-Hernandez Noelia ◽  
Jimenez-Acosta Francisco ◽  
Lorenzo-Villegas Dionisio L.
Keyword(s):  
Nutritional Status ◽  
Hair Follicle ◽  
Hair Loss ◽  
Growth Pattern ◽  
Hair Growth ◽  
Social Impact ◽  
Well Being ◽  
Growth Cycle ◽  
Hair Root ◽  
Body Side

The hair follicle is the unique organ that has the capacity of undergoing cyclic transformations following periods of growth (anagen), regression (catagen), and rest (telogen) regenerating itself to restart the cycle. The dynamic capacity of hair to growth and rest enables mammals to control hair growth and length in different body side and to change their coats. Unlike what is observed in many animals in which the pelage synchronously passes from one phase of the cycle to other all stages of growth cycle are simultaneously found in the human pelage, the growth pattern is a mosaic where the hair cycling staging of one hair root is completely independent of it nearest hair follicle, meaning that each follicular unit (FU) can contain follicles in different stages at any given time. A variety of factors, such as nutritional status, hormones, exposure to radiations, chemotherapy or radiotherapy, environmental pollution or drugs may affect hair growth, and affects the number of hairs, this progressive hair loss has a cosmetic and social impact that often significantly affects social and psychological well-being of the patient that suffers from this hair loss. Although a number of therapies, such as finasteride and minoxidil, are approved medications, a wide variety of classes of phytochemicals and natural products, including those present in ginseng are being testing. The purpose of this chapter is to focus on study the potential of ginseng and its metabolites in hair loss.

scholarly journals Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle

2001 ◽  
Vol 116 (4) ◽  
pp. 617-622 ◽  
Author(s):  
Jonathan J. Bull ◽  
Sven Mïller-Röver ◽  
Sejal V. Patel ◽  
Catherine M.T. Chronnell ◽  
Ian A. McKay ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Hair Follicle ◽  
Human Hair ◽  
Hair Growth ◽  
Growth Cycle ◽  
Human Hair Follicle

Disorders of Hair

2013 ◽  
Author(s):  
James Q Del Rosso
Keyword(s):  
Hair Loss ◽  
Alopecia Areata ◽  
Hair Growth ◽  
Growth Cycle ◽  
Hair Follicles ◽  
Common Type ◽  
Diagnosis And Treatment ◽  
Basic Knowledge ◽  
Androgenetic Alopecia ◽  
Broad Overview

A basic knowledge of the hair growth cycle is needed to evaluate disorders of hair growth. This chapter presents a broad overview of the physiology and evaluation of hair growth, as well as discussions of specific types of alopecia. The epidemiology, pathogenesis, diagnosis, and treatment of androgenetic alopecia, the most common type of nonscarring hair loss, are covered. Diffuse hair shedding is generalized hair loss over the entire scalp. Diagnosis and treatment of telogen effluvium, anagen arrest (anagen effluvium), and other causes of diffuse hair shedding are covered in detail. Alopecia areata, typically characterized by patchy hair loss; cicatricial alopecia, which results from permanent scarring of the hair follicles; and miscellaneous causes of hair loss are also discussed. Tables list the causes of diffuse and cicatricial alopecia, telogen effluvium, and miscellaneous chemicals and categories of drugs that can cause alopecia, as well as miscellaneous causes of hair loss. Included is an algorithm outlining the approach to diagnosing nonscarring alopecia, as well as a variety of clinical photographs. This review contains 9 highly rendered figures, 6 tables, and 42 references.

scholarly journals Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development

Cells ◽  
2019 ◽  
Vol 8 (5) ◽  
pp. 466 ◽  
Author(s):  
Pietro Gentile ◽  
Simone Garcovich
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Cell Growth ◽  
Mesenchymal Stem Cell ◽  
Hair Follicle ◽  
Hair Loss ◽  
Hair Growth ◽  
Follicle Development ◽  
Hair Regrowth ◽  
Hair Follicle Development

The use of stem cells has been reported to improve hair regrowth in several therapeutic strategies, including reversing the pathological mechanisms, that contribute to hair loss, regeneration of hair follicles, or creating hair using the tissue-engineering approach. Although various promising stem cell approaches are progressing via pre-clinical models to clinical trials, intraoperative stem cell treatments with a one-step procedure offer a quicker result by incorporating an autologous cell source without manipulation, which may be injected by surgeons through a well-established clinical practice. Many authors have concentrated on adipose-derived stromal vascular cells due to their ability to separate into numerous cell genealogies, platelet-rich plasma for its ability to enhance cell multiplication and neo-angiogenesis, as well as human follicle mesenchymal stem cells. In this paper, the significant improvements in intraoperative stem cell approaches, from in vivo models to clinical investigations, are reviewed. The potential regenerative instruments and functions of various cell populaces in the hair regrowth process are discussed. The addition of Wnt signaling in dermal papilla cells is considered a key factor in stimulating hair growth. Mesenchymal stem cell-derived signaling and growth factors obtained by platelets influence hair growth through cellular proliferation to prolong the anagen phase (FGF-7), induce cell growth (ERK activation), stimulate hair follicle development (β-catenin), and suppress apoptotic cues (Bcl-2 release and Akt activation).

scholarly journals Hair Growth Cycle Affects Hair Follicle Destruction by Ruby Laser Pulses

1998 ◽  
Vol 111 (1) ◽  
pp. 107-113 ◽  
Author(s):  
Tai-Yuan David Lin ◽  
Woraphong Manuskiatti ◽  
Christine C. Dierickx ◽  
William A. Farinelli ◽  
Marnie E. Fisher ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Hair Growth ◽  
Ruby Laser ◽  
Laser Pulses ◽  
Growth Cycle

scholarly journals Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms

2018 ◽  
Vol 19 (9) ◽  
pp. 2703 ◽  
Author(s):  
Bu Choi
Keyword(s):  
Hair Loss ◽  
Hair Growth ◽  
Social Impact ◽  
Molecular Mechanisms ◽  
Growth Potential ◽  
Environmental Toxicants ◽  
Androgenic Alopecia ◽  
Three Stages ◽  
Growth Promoting ◽  
Underlying Mechanisms

The functional aspect of scalp hair is not only to protect from solar radiation and heat/cold exposure but also to contribute to one’s appearance and personality. Progressive hair loss has a cosmetic and social impact. Hair undergoes three stages of hair cycle: the anagen, catagen, and telogen phases. Through cyclical loss and new-hair growth, the number of hairs remains relatively constant. A variety of factors, such as hormones, nutritional status, and exposure to radiations, environmental toxicants, and medications, may affect hair growth. Androgens are the most important of these factors that cause androgenic alopecia. Other forms of hair loss include immunogenic hair loss, that is, alopecia areata. Although a number of therapies, such as finasteride and minoxidil, are approved medications, and a few others (e.g., tofacitinib) are in progress, a wide variety of structurally diverse classes of phytochemicals, including those present in ginseng, have demonstrated hair growth-promoting effects in a large number of preclinical studies. The purpose of this review is to focus on the potential of ginseng and its metabolites on the prevention of hair loss and its underlying mechanisms.

scholarly journals Alopecia by COVID-19: About a Case

2021 ◽  
pp. 1-2
Author(s):  
Juan Tafur Delgado ◽  
Michael Muñoz Ortiz ◽  
Víctor Otero Marrugo ◽  
Juan Farak Gómez
Keyword(s):  
Emergency Department ◽  
Positive Result ◽  
Female Patient ◽  
Hair Loss ◽  
Clinical Picture ◽  
Medical Management ◽  
Hair Growth ◽  
Growth Cycle ◽  
Antigen Test ◽  
Limited Period

Some research that has been carried out in patients who have already undergone COVID-19, indicate that between 20%-30% of these will suffer intense hair loss, multiplied by 4 or 5 after 2 to 4 months later of the illness. This exaggerated hair loss is known as telogenic effluvium. In telogenic effluvium, it is produced by an alteration in the hair growth cycle that generates an alarming loss for a limited period of time. As in any infection or period of stress, the root of the hair weakens and months after having overcome it, the hair falls in an abnormal and exaggerated way. The objective of presenting this case is to describe one of the most important and rare dermatological manifestations, which has been derived from SARS-CoV-2 infection. We present the case of a 41-year-old female patient, who was admitted to the emergency department after presenting a clinical picture of 8 days of evolution consisting of dry cough, tachycardia and diaphoresis, for which the antigen test for SARS-CoV-2, revealing a positive result, so it was decided to enter for medical management.

scholarly journals Diffuse hair loss in women: causes and therapeutic approach

2020 ◽  
pp. 60-63
Author(s):  
O. O. Melnichenko ◽  
A. L. Piruzyan ◽  
I. M. Korsunskaya
Keyword(s):  
Hair Loss ◽  
Hair Growth ◽  
Clinical Effectiveness ◽  
Growth Cycle ◽  
Trigger Factor ◽  
Results Of Treatment ◽  
Trigger Event ◽  
Specialized Care ◽  
Post Menopause

Throughout human history, women have paid great attention to the beauty of their hair, and modern women are no exception. About 63% of young American women use different nutritional supplements to prevent hair loss. Diffuse hair loss is quite common in women and can occur against the background of various events: pregnancy, pre- and post-menopause, chronic diseases, etc. The most common is telogen effluvium (TE), which begins 2-3 months after the trigger event. Usually, TE process stops on its own, but can also become chronic. For many women, pregnancy and associated psycho-emotional stress become the triggering event, and in 75% of cases hair loss can become chronic.In fact, TE is a violation of the hair growth cycle. First of all, it is necessary to exclude the trigger factor from the patient's life and only then to start normalizing the hair growth cycle and improve the quality of hair follicle nutrition. The most effective topical remedy for the treatment of diffuse hair loss is minoxidil. The reasons for its clinical effectiveness have not been fully studied, but it is known that it prolongs the hair growth phase. Unfortunately, after cancellation of the drug, hair loss is often renewed. Avoiding these effects is possible with a comprehensive approach to therapy. Inclusion of additional components in the therapy scheme, such as vitamin and mineral complexes, growth stimulants, specialized care products, allows to maintain and improve the results of treatment with minoxidil. 

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