Design of a Genomics Curriculum: Competencies for Practicing Pathologists

2015 ◽  
Vol 139 (7) ◽  
pp. 894-900 ◽  
Author(s):  
Jennifer Laudadio ◽  
Jeffrey L. McNeal ◽  
Scott D. Boyd ◽  
Long Phi Le ◽  
Christina Lockwood ◽  
...  
Keyword(s):  
Medical Care ◽  
Working Group ◽  
Clinical Utility ◽  
Clinical Laboratory ◽  
Genomic Data ◽  
Educational Material ◽  
Learning Needs ◽  
Delivery Methods ◽  
Knowledge And Skills ◽  
Initial List

Context The field of genomics is rapidly impacting medical care across specialties. To help guide test utilization and interpretation, pathologists must be knowledgeable about genomic techniques and their clinical utility. The technology allowing timely generation of genomic data is relatively new to patient care and the clinical laboratory, and therefore, many currently practicing pathologists have been trained without any molecular or genomics exposure. Furthermore, the exposure that current and recent trainees receive in this field remains inconsistent. Objective To assess pathologists' learning needs in genomics and to develop a curriculum to address these educational needs. Design A working group formed by the College of American Pathologists developed an initial list of genomics competencies (knowledge and skills statements) that a practicing pathologist needs to be successful. Experts in genomics were then surveyed to rate the importance of each competency. These data were used to create a final list of prioritized competencies. A subset of the working group defined subtopics and tasks for each competency. Appropriate delivery methods for the educational material were also proposed. Results A final list of 32 genomics competency statements was developed. A prioritized curriculum was created with designated subtopics and tasks associated with each competency. Conclusions We present a genomics curriculum designed as a first step toward providing practicing pathologists with the competencies needed to practice successfully.

scholarly journals Formation of structure and content of the discipline “Obstetrics” to prepare students majoring in “Nursing”, area of specialization “Medical care”, educational degree of junior specialist at higher medical educational institutions

2021 ◽  
Vol 25 (1(97)) ◽  
pp. 108-114
Author(s):  
O. Kusa
Keyword(s):  
Medical Care ◽  
Teaching Methods ◽  
Professional Competence ◽  
Academic Discipline ◽  
Educational Material ◽  
Educational Institutions ◽  
Knowledge And Skills ◽  
Medical Interventions ◽  
Professional Activities ◽  
Educational Degree

The objective of the article - to acquaint teachers of medical educational institutions, including higher, at which professional medical colleges are created with a course of academic discipline “Obstetrics” to prepare students majoring in “Nursing”, area of specialization “Medical Care”, the educational degree of a junior specialist.Material and methods. This article describes the academic discipline “Obstetrics” which is an important subject for the professional development of future physicians.Results. The content of the discipline “Obstetrics” to prepare students majoring in “Nursing”, area of specialization “Medical Care”, the educational degree of a junior specialist, includes the program which describes the content of educational material, requirements for the organization of its mastering and educational and methodical complex are formulated.Conclusion. Developed program and teaching methods contribute to the formation of professional competence for future specialists. Learned in the process of studying the discipline of knowledge and skills determine the readiness of the paramedic for professional activities, allow to apply their set effectively and competently apply medical interventions in various obstetric conditions.

scholarly journals Towards Routine Implementation of Liquid Biopsies in Cancer Management: It Is Always Too Early, until Suddenly It Is Too Late

Diagnostics ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 103
Author(s):  
Maarten J. IJzerman ◽  
Jasper de Boer ◽  
Arun Azad ◽  
Koen Degeling ◽  
Joel Geoghegan ◽  
...  
Keyword(s):  
Clinical Utility ◽  
Clinical Laboratory ◽  
Genomic Analysis ◽  
Current Evidence ◽  
Liquid Biopsies ◽  
Blood Draw ◽  
Minimum Quality Standards ◽  
Cancer Management ◽  
Alternative Funding ◽  
And Performance

Blood-based liquid biopsies are considered a new and promising diagnostic and monitoring tool for cancer. As liquid biopsies only require a blood draw, they are non-invasive, potentially more rapid and assumed to be a less costly alternative to genomic analysis of tissue biopsies. A multi-disciplinary workshop (n = 98 registrations) was organized to discuss routine implementation of liquid biopsies in cancer management. Real-time polls were used to engage with experts’ about the current evidence of clinical utility and the barriers to implementation of liquid biopsies. Clinical, laboratory and health economics presentations were given to illustrate the opportunities and current levels of evidence, followed by three moderated break-out sessions to discuss applications. The workshop concluded that tumor-informed assays using next-generation sequencing (NGS) or PCR-based genotyping assays will most likely provide better clinical utility than tumor-agnostic assays, yet at a higher cost. For routine application, it will be essential to determine clinical utility, to define the minimum quality standards and performance of testing platforms and to ensure their use is integrated into current clinical workflows including how they complement tissue biopsies and imaging. Early health economic models may help identifying the most viable application of liquid biopsies. Alternative funding models for the translation of complex molecular diagnostics, such as liquid biopsies, may also be explored if clinical utility has been demonstrated and when their use is recommended in multi-disciplinary consensus guidelines.

scholarly journals Teacher Education and Teacher Identity in Transition

2010 ◽  
Vol 3 (2) ◽  
pp. 141-145
Author(s):  
Fern Snart
Keyword(s):  
Teacher Education ◽  
Learning Environments ◽  
Communication Technology ◽  
Teacher Identity ◽  
Citizenship Education ◽  
Global Citizenship ◽  
Teacher Education Programs ◽  
Learning Needs ◽  
Knowledge And Skills ◽  
Adult Lives

Within current Canadian learning environments, learners bring sophistication in areas such as communication/technology, a wide diversity of learning needs, and often an orientation towards social justice. This commentary refers to the ongoing responsiveness of teacher education programs to these evolving learner attributes, using as exemplars the areas of global citizenship education and technology integration. A backdrop for this discussion is the observation that the knowledge and skills that contribute to successful adult lives are also evolving.

Improvements in and clinical utility of a continuous-flow method for routine measurement of dialyzable (ultrafiltrable) calcium.

1979 ◽  
Vol 25 (11) ◽  
pp. 1939-1943 ◽  
Author(s):  
J Toffaletti ◽  
G N Bowers
Keyword(s):  
Continuous Flow ◽  
Clinical Utility ◽  
Clinical Laboratory ◽  
Serum Samples ◽  
The Past ◽  
Baseline Noise ◽  
Routine Service ◽  
Routine Measurement ◽  
Routine Clinical Laboratory ◽  
Continuous Flow Method

Abstract We describe modifications to the original continuous-flow procedure for dialyzable calcium (Clin. Chem. 23: 1258, 1977) needed to make the method more suitable for routine clinical laboratory use. The modifications simplify the continuous-flow (AutoAnalyzer) manifold, decrease baseline noise, increase the sensitivity, and permit use of a less-expensive fluorometer. Bias due to variation in serum processing is minimized by use of serum samples minimally exposed to air and a pH 7.40 buffer in place of the routinely processed sera and pH 7.30 buffer used formerly. Day-to-day precision (CV) during the past year for samples that included three different lots of quality-control sera was 2 to 3%. The analysis requires 200 micro L of serum, collected with minor additional precautions. We find that dialyzable calcium can be dependably measured in the routine service laboratory and show how this information is clinically more useful than is information on total calcium in serum.

Interlaboratory standardization of glycated hemoglobin determinations.

1986 ◽  
Vol 32 (2) ◽  
pp. 358-360 ◽  
Author(s):  
R R Little ◽  
J D England ◽  
H M Wiedmeyer ◽  
E M McKenzie ◽  
R Mitra ◽  
...  
Keyword(s):  
Research Laboratory ◽  
Clinical Utility ◽  
Glycated Hemoglobin ◽  
Clinical Laboratory ◽  
Reference Method ◽  
Hplc Method ◽  
Blood Samples ◽  
Standard Curve ◽  
The Mean ◽  
Liquid Chromatographic

Abstract As the clinical utility of glycated hemoglobin (gHb) measurement increases, so does the need for standardization of values between different methods and different laboratories. Using three different methods, we examined the feasibility of interlaboratory standardization of gHb measurement. A liquid-chromatographic (HPLC) system from our research laboratory was designated the reference method. For gHb standards we used erythrocyte hemolysates prepared from blood samples from nondiabetic and diabetic subjects. Values assigned to each standard were based on the mean of multiple gHb determinations by the HPLC method. A clinical laboratory routinely prepared hemolysates and assayed gHb by commercially available ion-exchange ("mini column") and affinity chromatographic methods. For each assay a standard curve was constructed and gHb values were derived from these curves. Samples analyzed in the clinical laboratory were also analyzed in the research laboratory and the curve-derived values were compared with the HPLC-measured values, to determine the accuracy of our interlaboratory standardization procedure. Correlations were excellent (r = 0.99). The lack of significant differences between calculated and HPLC-measured values indicates that interlaboratory standardization is feasible.

scholarly journals THE SPECIFICS OF THE PSYCHOLOGICAL ASPECT OF THE FORMATION OF STUDENTS’ PERSONAL AND METADISCIPLINARY COMPETENCIES IN TEACHING LITERATURE

2019 ◽  
pp. 257-262
Author(s):  
V. Karatkevich
Keyword(s):  
Lifelong Learning ◽  
Educational Material ◽  
Psychological Aspect ◽  
Learning Needs ◽  
Teaching Literature ◽  
Modern Education ◽  
Thinking Ability ◽  
Personal Competencies ◽  
Selection Of ◽  
Changing World

The society is interested in individuals capable of showing flexibility of thinking, ability to navigate in a changing world, mobile and creative. Provisioning today must also respond to these challenges of the time: to provide lifelong learning needs. The refore, one of the key problems of the modern education system is the formation of metadisciplinary and personal competencies aimed at adapting the student in a rapidly changing world. At the sametime, it is important to understand the psychological aspect of the formation of these competencies. The implementation of education through training, the creation of conditions for self-realization are the most important components of modern education. In this article deals with defines such concepts as upbringing in the psychological aspect and the psychological aspect of upbringing, presents the principles for the selection of educational material for the formation of metadisciplinary and personal competences.

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