scholarly journals Data Set for the Reporting of Oral Cavity Carcinomas: Explanations and Recommendations of the Guidelines From the International Collaboration of Cancer Reporting

2018 ◽  
Vol 143 (4) ◽  
pp. 439-446 ◽  
Author(s):  
Susan Müller ◽  
Sonja C. Boy ◽  
Terrence A. Day ◽  
Kelly R. Magliocca ◽  
Mary S. Richardson ◽  
...  

The International Collaboration on Cancer Reporting is a nonprofit organization whose goal is to develop evidence-based, internationally agreed-upon standardized data sets for each cancer site for use throughout the world. Providing global standardization of pathology tumor classification, staging, and other reporting elements will lead to the objective of improved patient management and enhanced epidemiologic research. Carcinomas of the oral cavity continue to represent a significant oncologic management burden, especially as changes in alcohol and tobacco use on a global scale contribute to tumor development. Separation of oral cavity carcinomas from oropharyngeal tumors is also important, as management and outcome are quite different when human papillomavirus association is taken into consideration. Topics such as tumor thickness versus depth of invasion, pattern of invasive front, extent and size of perineural invasion, and margin assessment all contribute to accurate classification and staging of tumors. This review focuses on the data set developed for Carcinomas of the Oral Cavity Histopathology Reporting Guide, with discussion of the key elements developed for inclusion.

2018 ◽  
Vol 143 (5) ◽  
pp. 603-609 ◽  
Author(s):  
Michelle D. Williams ◽  
Alessandro Franchi ◽  
Tim Helliwell ◽  
Susan Müller ◽  
Lester D. R. Thompson

Standardized pathologic reporting for cancers allows for improved communication for patient care and prognostic determination. If used universally, synoptic reporting enhances comparing data globally for scientific leverage. The International Collaboration on Cancer Reporting is a nonprofit organization whose mission is to develop evidence-based, universally available surgical pathology reporting data sets. Multiple different sites within the head and neck may be affected by mucosal melanoma, whose behavior and patient outcome are not equivalent to carcinomas of the corresponding sites. Factors such as Breslow thickness and Clark depth of invasion applied to cutaneous melanomas do not yield any prognostic significance in mucosal sites, and thus are not meaningful. Likewise, margin assessment is unique in head and neck sites. Further, the genetic profile of mucosal melanomas is different from that of most cutaneous tumors. Thus, within the head and neck region, mucosal melanoma is a distinct entity for which a dedicated data set was developed for implementation. The elements that comprise the core (required) and noncore (recommended) elements are discussed.


2018 ◽  
Vol 143 (4) ◽  
pp. 432-438 ◽  
Author(s):  
Tim Helliwell ◽  
Rebecca Chernock ◽  
Jane E. Dahlstrom ◽  
Nina Gale ◽  
Jonathan McHugh ◽  
...  

The International Collaboration on Cancer Reporting is a nonprofit organization whose mission is to develop evidence-based, universally available surgical pathology reporting data sets. Standardized pathologic reporting for cancers facilitates improved communication for patient care and prognosis and the comparison of data between countries to progressively improve clinical outcomes. Laryngeal cancers are often accompanied by significant morbidity, although surgical advances (such as transoral endoscopic laser microresection and transoral robotic surgery) provide new alternatives. The anatomy of the larynx is complex, with an understanding of the exact anatomic sites and subsites, along with recognizing anatomic landmarks, being crucial to classification and prognostication. This review outlines the data set developed for the histopathology reporting in Carcinomas of the Hypopharynx, Larynx and Trachea and discusses the main elements required and recommended for reporting.


2018 ◽  
Vol 143 (4) ◽  
pp. 447-451 ◽  
Author(s):  
James S. Lewis ◽  
David J. Adelstein ◽  
Abbas Agaimy ◽  
Diane L. Carlson ◽  
William C. Faquin ◽  
...  

The International Collaboration on Cancer Reporting was established to internationally unify and standardize the pathologic reporting of cancers based on collected evidence, as well as to allow systematic data collection across institutions and countries to guide cancer care in the future. An expert panel was convened to identify the minimum data set of elements that should be included in cancer reporting from tumors of the nasopharynx and oropharynx. Specifically, there has been a significant change in practice as a result of identifying oncogenic viruses, including human papillomavirus and Epstein-Barr virus, because they preferentially affect the oropharynx and nasopharynx, respectively. For these anatomic sites, when viral association is taken into account, usually reported elements of in situ versus invasive tumor, depth of invasion, and degree of differentiation are no longer applicable. Thus, guidance about human papillomavirus testing in oropharyngeal carcinomas and Epstein-Barr virus testing in nasopharyngeal carcinomas is highlighted. Further, the clinical and the pathologic differences in staging as proposed by the 8th edition of the Union for International Cancer Control are incorporated into the discussion, pointing out several areas of continued study and further elaboration. A summary of the International Collaboration on Cancer Reporting guidelines for oropharyngeal and nasopharyngeal carcinomas is presented, along with discussion of the salient evidence and practical issues.


2018 ◽  
Vol 143 (5) ◽  
pp. 578-586 ◽  
Author(s):  
Raja R. Seethala ◽  
Albina Altemani ◽  
Robert L. Ferris ◽  
Isabel Fonseca ◽  
Douglas R. Gnepp ◽  
...  

The International Collaboration on Cancer Reporting is a nonprofit organization whose goal is to develop evidence-based, internationally agreed-upon standardized data sets for each anatomic site, to be used throughout the world. Providing global standardization of pathology tumor classification, staging, and other reporting elements will lead to achieving the objective of improved patient management and enhanced epidemiologic research. Salivary gland carcinomas are relatively uncommon, and as such, meaningful data about the many histologic types are not easily compared. Morphologic overlap between tumor types makes accurate classification challenging, but there are often significant differences in patient outcomes. Therefore, issues related to tumor type, tumor grading, high-grade transformation, extent of invasion, number and size of nerves affected, and types of ancillary studies are discussed in the context of daily application to specimens from these organs. This review focuses on the data set developed for salivary gland carcinomas with discussion of the key core and noncore elements developed for inclusion by an international expert panel of head and neck and oral-maxillofacial pathologists and surgeons.


2019 ◽  
Vol 144 (2) ◽  
pp. 196-206 ◽  
Author(s):  
David N. Louis ◽  
Pieter Wesseling ◽  
Sebastian Brandner ◽  
Daniel J. Brat ◽  
David W. Ellison ◽  
...  

Context.— Standards for pathology reporting of cancer are foundational to national and international benchmarking, epidemiology, and clinical trials, with international standards for pathology reporting of cancer being undertaken through the International Collaboration on Cancer Reporting (ICCR). Objective.— To develop standardized templates for brain tumor diagnostic pathology reporting. Design.— As a response to the 2016 updated 4th edition of the WHO (World Health Organization) Classification of Tumours of the Central Nervous System (2016 CNS WHO), an expert ICCR committee developed data sets to facilitate reporting of brain tumors that are classified histologically and molecularly by the 2016 CNS WHO; as such, this represents the first combined histologic and molecular ICCR data set, and required a novel approach with 3 highly related data sets that should be used in an integrated manner. Results.— The current article and accompanying ICCR Web site describe reporting data sets for central nervous system tumors in the hope that they provide easy-to-use and highly reproducible means to issue diagnostic reports in consort with the 2016 CNS WHO. Conclusions.— The consistent use of these templates will undoubtedly prove useful for patient care, clinical trials, epidemiologic studies, and monitoring of neuro-oncologic care around the world.


Author(s):  
Chanjuan Shi ◽  
Brian D. Badgwell ◽  
Heike I. Grabsch ◽  
Michael K. Gibson ◽  
Seung-Mo Hong ◽  
...  

Context.— A standardized detailed surgical pathology report is the cornerstone of gastric cancer management. Objective.— To guide management and prognostication for patients with gastric carcinomas globally, the International Collaboration on Cancer Reporting aimed to produce an evidence-based international pathology reporting data set with a panel of globally recognized expert pathologists and clinicians. Design.— Based on published guidelines/data sets for gastric carcinomas, a working draft was developed by the chair of the expert panel of pathologists and clinicians. The draft was then circulated to the panel and discussed in a series of teleconferences and email communications until consensus was achieved. The draft data set was uploaded on the International Collaboration on Cancer Reporting Web site for public comment. The data set was reviewed in consideration of the feedback, and a final version was approved by the panel. Results.— This data set was developed for gastrectomy specimens for primary gastric carcinomas, including neuroendocrine carcinomas and mixed neuroendocrine-nonneuroendocrine neoplasms. Well-differentiated neuroendocrine tumors, nonepithelial malignancies, and secondary tumors were excluded from this data set. The final data set contains 15 core (required) elements and 8 noncore (recommended) elements. A commentary is provided for each element. Conclusions.— The International Collaboration on Cancer Reporting has published freely available, evidence-based data sets for gastric cancer reporting. Standardized reporting has been shown to improve patient care and facilitates data exchange and analysis for quality assurance, cancer epidemiology, and clinical and basic research.


2018 ◽  
Vol 143 (5) ◽  
pp. 587-592 ◽  
Author(s):  
Pieter J. Slootweg ◽  
Edward W. Odell ◽  
Daniel Baumhoer ◽  
Roman Carlos ◽  
Keith D. Hunter ◽  
...  

A data set has been developed for the reporting of excisional biopsies and resection specimens for malignant odontogenic tumors by members of an expert panel working on behalf of the International Collaboration on Cancer Reporting, an international organization established to unify and standardize reporting of cancers. Odontogenic tumors are rare, which limits evidence-based support for designing a scientifically sound data set for reporting them. Thus, the selection of reportable elements within the data set and considering them as either core or noncore is principally based on evidence from malignancies affecting other organ systems, limited case series, expert opinions, and/or anecdotal reports. Nevertheless, this data set serves as the initial step toward standardized reporting on malignant odontogenic tumors that should evolve over time as more evidence becomes available and functions as a prompt for further research to provide such evidence.


2015 ◽  
Vol 8 (5) ◽  
pp. 4817-4858
Author(s):  
J. Jia ◽  
A. Rozanov ◽  
A. Ladstätter-Weißenmayer ◽  
J. P. Burrows

Abstract. In this manuscript, the latest SCIAMACHY limb ozone scientific vertical profiles, namely the current V2.9 and the upcoming V3.0, are extensively compared with ozone sonde data from the WOUDC database. The comparisons are made on a global scale from 2003 to 2011, involving 61 sonde stations. The retrieval processors used to generate V2.9 and V3.0 data sets are briefly introduced. The comparisons are discussed in terms of vertical profiles and stratospheric partial columns. Our results indicate that the V2.9 ozone profile data between 20–30 km is in good agreement with ground based measurements with less than 5% relative differences in the latitude range of 90° S–40° N (with exception of the tropical Pacific region where an overestimation of more than 10% is observed), which corresponds to less than 5 DU partial column differences. In the tropics the differences are within 3%. However, this data set shows a significant underestimation northwards of 40° N (up to ~15%). The newly developed V3.0 data set reduces this bias to below 10% while maintaining a good agreement southwards of 40° N with slightly increased relative differences of up to 5% in the tropics.


2013 ◽  
Vol 137 (8) ◽  
pp. 1054-1062 ◽  
Author(s):  
Kirk D. Jones ◽  
Andrew Churg ◽  
Douglas W. Henderson ◽  
David M. Hwang ◽  
Jenny Ma Wyatt ◽  
...  

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