Hepatoprotective effect of methanolic extract of the leaves of Kydia calycina on carbon tetrachloride induced hepatotoxicity in albino rats

2011 ◽  
Vol 5 (16) ◽  
Author(s):  
H. Parameshwar
Keyword(s):  
Carbon Tetrachloride ◽  
Methanolic Extract ◽  
Hepatoprotective Effect ◽  
Albino Rats

Hepatoprotective Effect of Cornus mas Fruits Extract Against Carbon Tetrachloride-Induced Hepatic Damage in Male Albino Rats

Thrita ◽  
2014 ◽  
Vol 3 (2) ◽  
Author(s):  
Mohammad Hossein Somi ◽  
Nafiseh Banihabib ◽  
Gholamreza Dehghan ◽  
Masoud Es. Haghi ◽  
Farid Panahi
Keyword(s):  
Carbon Tetrachloride ◽  
Hepatic Damage ◽  
Hepatoprotective Effect ◽  
Albino Rats ◽  
Cornus Mas

scholarly journals Hepatoprotective effect of aqueous extract of Melothria perpusilla against carbon tetrachloride induced liver injury in albino rats

2017 ◽  
Vol 5 (3) ◽  
pp. 806 ◽  
Author(s):  
Nokul S. Yengkhom ◽  
Ngangom Gunindro ◽  
Sania M. Kholi ◽  
Rakesh S. Moirangthem ◽  
Bharati D. Rajkumari
Keyword(s):  
Carbon Tetrachloride ◽  
Liver Injury ◽  
Aqueous Extract ◽  
Liquid Paraffin ◽  
Herbal Medicines ◽  
Modern Medicine ◽  
Hepatoprotective Effect ◽  
Albino Rats ◽  
Group Iii ◽  
Group I

Background: In absence of reliable hepatoprotective drug in modern medicine, the traditional herbal medicines have been emphasized. Present study was designed to assess hepatoprotective effect of aqueous extract of Melothria perpusilla (AEMP) against carbon tetrachloride (CCl4) induced liver injury.Methods: Five groups of animals with 6 rats in each were treated for 7 days.  Group I received 1% gum acacia in distilled water (1 ml/200 g p.o.) daily.  Group II, III, IV and V received CCl4 in liquid paraffin (1 ml/kg s.c.) on day 2, 4 and 6. Group III, IV and V were treated respectively with silymarin (100 mg/kg p.o.), AEMP- 200 and 400 mg/kg p.o. daily. On day 8, liver injury was assessed by measuring serum ALT, AST, ALP and bilirubin.Results: ALT, AST, ALP and bilirubin were significantly reduced in groups receiving both CCl4 and AEMP when compared with CCl4 treated group.Conclusions: AEMP produced hepatoprotective effect against CCl4 induced liver injury.

scholarly journals Hepatoprotective Effect of Senna mimosoides Aqueous Leaf Extract Against Carbon Tetrachloride Induced Hepatotoxicity in Albino Rats

2020 ◽  
Vol 13 (3) ◽  
pp. 100-106
Author(s):  
Nworah Florence N ◽  
Nkwocha Chinelo Ch ◽  
Nwachukwu Justus Nma ◽  
Nwodo Okwesili Fred Chile
Keyword(s):  
Carbon Tetrachloride ◽  
Leaf Extract ◽  
Hepatoprotective Effect ◽  
Albino Rats ◽  
Aqueous Leaf Extract

scholarly journals HEPATOPROTECTIVE EFFECTS OF POLYHERBAL FORMULATION AGAINST CARBON TETRACHLORIDE-INDUCED HEPATIC INJURY IN ALBINO RATS: A TOXICITY SCREENING APPROACH

2016 ◽  
Vol 10 (1) ◽  
pp. 192 ◽  
Author(s):  
Bhumika Yogi ◽  
Ashutosh Mishra
Keyword(s):  
Carbon Tetrachloride ◽  
Hepatic Injury ◽  
Methanolic Extract ◽  
Hepatoprotective Activity ◽  
Calotropis Procera ◽  
Albino Rats ◽  
Gymnema Sylvestre ◽  
Toxicity Screening ◽  
Lawsonia Inermis ◽  
Polyherbal Formulation

ABSTRACTObjective: To investigate the hepatoprotective activity of aqueous methanolic extract of polyherbal formulation and individual extracts of Calotropisprocera, Gymnema sylvestre, and Lawsonia inermis leaves.Methods: The hepatoprotective activity of the formulation and extracts were assessed on the basis of histopathological changes in liver of carbontetrachloride-induced hepatotoxic rats.Results: The result of present studies strongly indicates that the hepatoprotective property of polyherbal formulation as evidenced by less damagedhepatocytes cells.Conclusion: Polyherbal formulation revealed excellent hepatoprotective profile as compared to individual plants due to synergistic effect producedby different phytochemicals present in the formulation.Keywords: Calotropis procera, Gymnema sylvestre, Lawsonia inermis, Carbon tetrachloride.

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