scholarly journals Comparison of Long-term Prognosis in Siblings with Dentinogenesis Imperfecta depending on the Timing of the Treatment Intervention : Case Reports

2021 ◽  
Vol 48 (2) ◽  
pp. 237-244
Author(s):  
Gimin Kim ◽  
Jaesik Lee
Keyword(s):  
Case Reports ◽  
Dentinogenesis Imperfecta ◽  
Autosomal Dominant Trait ◽  
Rapid Destruction ◽  
Tooth Attrition ◽  
Treatment Objective ◽  
The Difference ◽  
Long Term Prognosis ◽  
Treatment Procedures

Dentinogenesis imperfecta (DI) is a hereditary disorder of dentinal defect. It is generally inherited as a single autosomal dominant trait. DI usually affects both the primary and permanent dentition. Affected teeth have various types of discolorations, rapid destruction of the dentin, and severe attrition. In radiologic view, the affected teeth have bulbous crowns, short roots and narrow or closed pulp chambers. The treatment objective is to prevent additional attrition and recover the vertical dimension of occlusion.The aim of this report was to present the long-term prognosis in 15 years in a pair of siblings. Both the patients had DI with tooth attrition and discoloration. Different treatment procedures were used, depending on the difference in the timing of intervention. The first patient saved most of his teeth. The second patient had all of her teeth extracted. This report could be helpful for early diagnosis and overall treatment of DI.

scholarly journals Fibromuscular dysplasia with recurrence after “long-term” following percutaneous transcatheter renal angioplasty: two case reports with a review of 26 patients

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Shuntaro Oribe ◽  
Takafumi Toyohara ◽  
Eikan Mishima ◽  
Takehiro Suzuki ◽  
Koichi Kikuchi ◽  
...  
Keyword(s):  
Fibromuscular Dysplasia ◽  
Age Of Onset ◽  
Case Reports ◽  
Case Presentation ◽  
Renal Angioplasty ◽  
Long Term Follow Up ◽  
Percutaneous Transluminal Renal Angioplasty ◽  
The Difference

Abstract Background Fibromuscular dysplasia (FMD) often causes renal artery stenosis with renovascular hypertension. Recent clinical outcomes encourage percutaneous transluminal renal angioplasty (PTRA) to treat FMD; however, the necessary follow-up period remains unclear. Moreover, previous studies have not revealed the difference in the period until recurrence between two major types of FMD—multifocal and focal. Case presentation We describe two patients with multifocal FMD who developed hypertension during their teenage years and had recurrence of FMD > 10 years after PTRA. We further examined the types of FMD and age of onset in 26 patients who underwent PTRA. The period until recurrence of multifocal FMD was longer than that of focal FMD. Moreover, patients with early-onset multifocal FMD are likely to have a delayed recurrence after PTRA compared to other types. Conclusions Our report suggests that patients with multifocal FMD, especially those with onset at an early age, may need long-term follow-up for at least ≥ 10 years.

Cholesterol Embolism in Intensive Care Patients

1993 ◽  
Vol 8 (2) ◽  
pp. 91-102 ◽  
Author(s):  
Lisa L. Kirkland
Keyword(s):  
Case Reports ◽  
Supportive Therapy ◽  
Hemodynamic Instability ◽  
Cholesterol Embolism ◽  
Intensive Care Patients ◽  
Major Organ ◽  
Life Threatening ◽  
Perineal Gangrene ◽  
Long Term Prognosis

Four case reports are presented, followed by a discussion of the acute, potentially life-threatening manifestations of the cholesterol embolism syndromes. Every major organ system except the lungs may be directly affected by cholesterol emboli; devastating consequences encompass cerebral, myocardial, spinal cord, intestinal, renal, and other visceral organ infarction, as well as peripheral and perineal gangrene. Additional complications include severe hypertension, gastrointestinal bleeding, and hemodynamic instability. Anticoagulants and thrombolytic therapy may exacerbate atheromatous embolism and are relatively contraindicated. Aggressive supportive therapy may improve chances of survival, but long-term prognosis is poor. Prevention remains the most important aspect in this devastating disorder.

Medium- and long-term prognostic validity of competing classification proposals for the former somatoform disorders

2017 ◽  
Vol 47 (10) ◽  
pp. 1719-1732 ◽  
Author(s):  
S. Schumacher ◽  
W. Rief ◽  
K. Klaus ◽  
E. Brähler ◽  
R. Mewes
Keyword(s):  
Healthcare Utilization ◽  
Somatic Symptom ◽  
Somatoform Disorders ◽  
Longitudinal Design ◽  
The Difference ◽  
Long Term Prognosis ◽  
Baseline Sample ◽  
Relevant Factors

BackgroundDSM-5 introduced a fundamental revision of the category of somatoform disorders, which resulted in the new somatic symptom disorder (SSD) and related disorders. However, prognostic validity of SSD remains unclear, while other classification proposals, such as bodily distress disorder (BDD) or polysymptomatic distress disorder (PSDD), might be promising alternatives for the new ICD-11. Therefore, the comparison of the different approaches concerning long-term prognosis of disorder-relevant factors is of special interest.MethodIn a longitudinal design (baseline, 1-year, and 4-year follow-up), the three proposals (SSD, BDD, PSDD) were compared in an age-representative sample of the German general population (N = 321). To this end, the baseline sample was divided into three independent pairs of groups (with/without SSD, with/without BDD, with/without PSDD). It was tested how well each approach differentiated with regard to medium- and long-term healthcare utilization, number of symptoms, and impairment.ResultsCriteria for BDD distinguished best with regard to future healthcare utilization resulting in a large-sized effect (f = 0.44) for the difference between persons with and without BDD, while SSD and PSDD revealed only medium-sized effects (f = 0.28 and f = 0.32) between subjects with and without diagnosis. The three proposals distinguished equally well with regard to future subjective impairment (between f = 0.39 and f = 0.41) and the number of reported symptoms (between f = 0.77 and f = 0.83).ConclusionIn accordance with our data regarding prognostic validity, the current draft of the WHO group is based on the BDD proposal. However, existing limitations and weaknesses of the present proposal for the ICD-11 are further discussed.

scholarly journals Short Implants in Partially Edentulous Maxillae and Mandibles: A 10 to 20 Years Retrospective Evaluation

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Diego Lops ◽  
Eriberto Bressan ◽  
Gianluca Pisoni ◽  
Niccolò Cea ◽  
Boris Corazza ◽  
...  
Keyword(s):  
High Reliability ◽  
Survival Rates ◽  
Success Rates ◽  
Marginal Bone Loss ◽  
Probing Depth ◽  
Short Implants ◽  
Single Crown ◽  
The Difference ◽  
Long Term Prognosis

Purpose.Evaluation of the short implant (8 mm in height) long-term prognosis and of the implant site influence on the prognosis.Methods.A longitudinal study was carried out on 121 patients (57 males and 64 females) consecutively treated with 257 implants. 108 implants were short.Results.Four (3.6%) short implants supporting fixed partial prostheses failed. Similarly, three standard implants supporting fixed partial prostheses and one supporting single-crown prosthesis failed. Mean marginal bone loss (MBL) and probing depth (PD) of short and standard implants were statistically comparable (P>.05). The 20-year cumulative survival rates of short and standard implants were 92.3 and 95.9%, respectively. The cumulative success rates were 78.3 and 81.4%. The survival rates of short implants in posterior and anterior regions were comparable: 95 and 96.4%, respectively. The difference between survival rates was not significant (P>.05).Conclusions.The high reliability of short implants in supporting fixed prostheses was confirmed. Short and standard implants long-term prognoses were not significantly different. The prognosis of short implants in posterior regions was comparable to that of in anterior regions. Nevertheless, a larger sample is required to confirm this trend.

scholarly journals Direct Restorations for Anterior Esthetic Rehabilitation and Smile Symmetry Recovery: Two Case Reports

Symmetry ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1848
Author(s):  
Inês Amaro ◽  
José Saraiva ◽  
Ana Catarina Gomes ◽  
Ana Araújo ◽  
Carlos Miguel Marto ◽  
...  
Keyword(s):  
Functional Outcomes ◽  
Orthodontic Treatment ◽  
Case Reports ◽  
Cost Effective ◽  
Minimally Invasive Approach ◽  
Invasive Approach ◽  
Anterior Teeth ◽  
Long Term Prognosis ◽  
And Function

Esthetics is an increasing concern for patients, particularly in anterior teeth. The current approaches to manage the esthetic demands include options such as prosthodontic rehabilitation, orthodontic treatment, and direct restorations. Direct restorative procedures for anterior teeth have become a reliable alternative, since current composite materials can mimic teeth’s esthetics and function perfectly. This article describes two clinical cases of anterior esthetic rehabilitations where the direct reshaping of the four maxillary incisors was performed using the buccolingual layering technique with the help of a silicone index. In Case 1, a diastema closure was also performed, whereas in Case 2, the replacement of old restorations was also carried out. It was possible to achieve excellent final esthetic results in both cases, recovering the smile symmetry, and both patients were satisfied. The literature supports the use of direct restorations in the anterior region with very good long-term prognosis. It is a minimally invasive approach that is reversible, repairable, cost-effective, and when combined with layering techniques and adequate restorative materials, it is possible to achieve good esthetic and functional outcomes. However, regular maintenance appointments are mandatory, and all cases should be carefully planned to ensure predictable and long-lasting results.

scholarly journals Intraoperative pH Is a Reliable Prognostic Factor for Patients With Periampullary Carcinoma Undergoing Pancreaticoduodenectomy

2021 ◽  
Vol 11 ◽  
Author(s):  
Chao Dang ◽  
Min Wang ◽  
Tingmei Wang ◽  
Renyi Qin
Keyword(s):  
Prognostic Factor ◽  
Operating Characteristic ◽  
Ph Value ◽  
Characteristic Curve ◽  
Low Ph ◽  
Periampullary Carcinoma ◽  
Short Term ◽  
The Difference ◽  
Long Term Prognosis

A reliable prognostic factor for periampullary carcinoma is critical to improve surgical outcomes. Intraoperative acidosis reflects the incidence of intraoperative adverse events and impact the prognosis. In this study, 612 patients with periampullary carcinoma who underwent pancreaticoduodenectomy (PD) were divided into high- and low-pH groups according to the cut-off value of receiver operating characteristic curve (7.34). Through statistical analysis of the difference between the high- and low-pH group, it was found that the low-pH group had worse short-term prognosis than the high pH group, and intraoperative pH was an independent prognostic factor for patients with periampullary carcinoma undergoing PD. In addition, patients who underwent laparoscopic pancreaticoduodenectomy had a more alkaline pH after surgery. This is of great help for early judgment of short-term and even long-term prognosis of patients with pancreatic cancer after surgery, and can even guide clinicians to improve prognosis by early adjustment of pH value.

Effect of platelet count on long-term prognosis of cerebral infarction

2020 ◽  
Vol 38 (3) ◽  
pp. 265-270
Author(s):  
Fei Ye ◽  
Guan-Shui Bao ◽  
Heng-Shi Xu ◽  
Pan-Pan Deng
Keyword(s):  
Cerebral Infarction ◽  
Analysis Of Variance ◽  
Repeated Measures ◽  
Repeated Measures Analysis ◽  
Function Recovery ◽  
Preventive Drug ◽  
The Difference ◽  
Long Term Prognosis ◽  
One Year

Objective: This study aimed to analyze the correlation between platelet (PLT) count and the modified Rankin scale (mRS) in patients with cerebral infarction (CI) at the later stage of rehabilitation, which can be used to guide the secondary prevention strategy of CI. Methods: A total of 180 CI patients were divided into three groups according to PLT count: low PLT group (<125×109/L), medium PLT group (126– 225×109/L) and high PLT group (>226×109/L). The mRS was evaluated after three months and one year, respectively, and the difference in long-term prognosis between groups was analyzed. The mRS is an ordered scale coded from 0 (no symptoms at all) through 5 (severe disability) 6 (death). Results: Finally, a total of 99 patients had complete data. The results of the multiple comparisons among the three groups were as follows: the analysis of variance of the mRS at three months after onset yielded F = 6.714 and P = 0.002, and the difference was statistically significant. The mRS was lowest in the medium PLT group (2.09±1.465), and neurological function recovery was the best. After one year, the mRS for the medium PLT group was the lowest (1.49±1.523), with F = 6.860 and P = 0.002. The repeated measures analysis of variance revealed that the effect of continuous rehabilitation was significant in the interval from three months to one year after onset (F = 35.528, P < 0.001). This was very significant, especially for patients taking aspirin (F = 50.908, P < 0.001). However, for patients who did not take aspirin, the effect of continuous rehabilitation was not obvious during the nine months, and the difference between the results of two mRS measurements was not statistically significant (F = 1.089, P = 0.308). Conclusions: Patients with a PLT count of 126– 225×109/L had the lowest mRS between three months and one year after onset, but had the best recovery of nerve function. Patients who persisted in taking aspirin continued to significantly recover during the 9-month period, from three months to one year after onset. Aspirin is not only a secondary preventive drug, but also an important drug to promote the rehabilitation of CI patients.

Alternativas para reabilitação com implantes dentários em mandíbula posterior atrófica

2020 ◽  
Vol 12 (45) ◽  
pp. 16-23
Author(s):  
Isabela Polesi Bergamaschi ◽  
Gabriel Albuquerque Guillen ◽  
Felipe Germoglio Cardoso Macêdo ◽  
Tarcio Hiroshi Ishimine Skiba ◽  
Bruno Costa Martins de Sá ◽  
...  
Keyword(s):  
Case Reports ◽  
Surgical Techniques ◽  
Inferior Alveolar Nerve ◽  
Bone Augmentation ◽  
Common Condition ◽  
Augmentation Techniques ◽  
Long Term Prognosis ◽  
Edentulous Patients ◽  
Nerve Transposition

An adequate bone volume is mandatory for a favorable long-term prognosis in patients treated with dental implants. The vertical deficiency of posterior mandible is a common condition in partially edentulous patients, in which vertical bone augmentation procedures or inferior alveolar nerve transposition become necessary for the dental implant rehabilitation. Thus, the aim of this study was to discuss options of vertical bone augmentation techniques in atrophic posterior mandibles and to present, as case reports, alternatives for the rehabilitation of patients with this condition. So, three alternatives of treatment were presented: the use of Cytoplast titanium-reinforced membrane over autogenous and xenogenous particulate bone graft; sandwich osteotomy; and nerve transposition. In the three reported cases, the chosen surgical techniques showed to be appropriated and allowed the placement of longer implants. No significant complications were observed and all the patients were satisfied with the performed treatment. It is possible to conclude that the reconstruction of atrophic posterior mandible remains a challenge to the professionals, who must know the various existing techniques and choose the most suitable one to each patient.

scholarly journals Quality of life and health of opioid-dependent subjects in India

2014 ◽  
Vol 05 (04) ◽  
pp. 363-368 ◽  
Author(s):  
Om Prakash Giri ◽  
Mona Srivastava ◽  
Ravi Shankar
Keyword(s):  
Quality Of Life ◽  
Substance Abusers ◽  
Care Center ◽  
Tertiary Care ◽  
Normal Subjects ◽  
The Difference ◽  
Long Term Prognosis ◽  
The Impact

ABSTRACT Background and Objectives: The quality of life (QoL) of substance abusers is known to be severely impaired. This study was carried out to assess the impact of opioid dependence on the QoL of subjects and compared it with the normal subjects. Materials and Methods: Based on specified inclusion criteria a total of 47 subjects were recruited from a tertiary care center from India. The WHOQoL-BREF scale domain scores obtained at baseline were compared to that of normal subjects. An assessment of dysfunction and reasons for continuing and other parameters were assessed. Results: WHOQoL-BREF domains (Physical, Psychological, Social relationships and Environment) showed significantly lower scores and the difference was statistically significant. Interpretation and Conclusions: The results showed that QoL is an important parameter in assessment of substance abusers and can be used for long-term prognosis of these individuals.

scholarly journals Two case reports and a literature review on eosinophilic fasciitis

2021 ◽  
Vol 30 (1) ◽  
pp. 33-44
Author(s):  
Diana Mazilu ◽  
◽  
Ioana Saulescu ◽  
Ruxandra Ionescu ◽  
◽  
...  
Keyword(s):  
Subcutaneous Tissue ◽  
Case Reports ◽  
Unknown Etiology ◽  
Eosinophilic Fasciitis ◽  
Physical Factors ◽  
Systemic Glucocorticoids ◽  
Typical Aspect ◽  
Peau D’Orange ◽  
Long Term Prognosis

Eosinophilic fasciitis is a rare disorder of unknown etiology and poorly understood pathogenesis. It may be triggered by excessive exercise, physical factors such as radiation therapy, exposure to certain medications, infections, the initiation of hemodialysis and some other medical conditions. Skin modifications appear with collagenous thickening of the subcutaneous fascia with typical aspect of “peau d’orange” and the “groove sign”. Arthritis, myalgia, myositis, neuropathies may occur. The majority of patients have peripheral blood eosinophilia. The diagnosis is confirmed with a full thickness incisional biopsy of skin and subcutaneous tissue down to the muscle surface and fascia. Systemic glucocorticoids are the mainstay of treatment, but some patients require additional immunosuppressive therapy. The long-term prognosis of this disease is unknown and in some cases the disease may releapse. We describe two patients with eosinophilic fasciitis, their evolution and complications, associating other pathologies: morphea and antiphospholipid syndrome, making the diagnosis and the treatment more challenging.

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