scholarly journals THE ORGANISATION OF DRILL PRODUCTION AT A NEOLITHIC LITHIC WORKSHOP SITE OF BAI BEN, CAT BA ISLAND, VIETNAM

Author(s):  
Dong Truong Nguyen ◽  
Chris Clarkson

We investigate stone drill point production, use, maintenance, and discard from a technological perspective at the Late Neolithic workshop of Bai Ben on Cat Ba Island, Northeastern Vietnam. Bai Ben contains over 18,000 retouched chert flakes classified as drill points and dating to c.3000BP. Large scale production of drills most likely took place for reasons of mass production of drilled organic and inorganic objects. Few of such drilled objects are found at the site, perhaps due to poor organic preservation or removal of finished objects for trade and exchange. An analysis of attribute on drills and cores examines the time-ordering of dimensional and morphological changes as reduction continued at the site. The research finds that drills were produced from a diverse range of nodules sizes, blanks, core technologies and raw materials, but similar blanks were selected to produce very similar drill point forms.

2021 ◽  
Vol 18 ◽  
Author(s):  
Wenhua Ou ◽  
Ruolin Wang ◽  
Ruonan Liu ◽  
Hong Huang

: α-Monochlorocyclododecanone was synthesized from cyclododecane and 1,3-Dichloro-5,5-dimethylhydantoin (DCDMH) catalyzed with silica gel in MeOH. The product was obtained by crystallization with nearly 85% yield. The presented method used cheap raw materials, mild reaction conditions, simple separation method and environment-friendly process. Additionally, the current synthesis provided an ideal approach for large-scale production.


1974 ◽  
Vol 9 (2-3) ◽  
pp. 167-177
Author(s):  
Willy Østreng

This article examines the possible political and economic effects of large-scale mineral extraction from the seabed. The findings presented indicate that development in new territories may conceivably serve to exacerbate existing conflict dimensions, notably the North/South dimension in global politics. Because of the developed countries' monopoly on know-how and economic capability, exploration and exploitation of the inorganic resources of the ocean floor has de facto been the exclusive domain of these countries. On the basis of this the author shows that if large-scale production of seabed resources should become a reality in the near future, the underdeveloped countries will be forced to watch it from the sidelines. As a consequence, the exploitation of offshore raw materials will probably contribute to the further widening of the gap between developed and underdeveloped countries. Further commenting on the fact that the latter today are the main producers of the most promising seabed resources, the author expresses the view that exploitation will have a detrimental effect on the economics of the Third World countries, since it might lead to overproduction and price reductions.


1995 ◽  
Vol 6 ◽  
pp. 119-134 ◽  
Author(s):  
Michael P. Smyth ◽  
Christopher D. Dore ◽  
Hector Neff ◽  
Michael D. Glascock

AbstractThis paper reports results of the first neutron-activation analysis (NAA) of ancient pottery wares and clays from the Puuc region of Yucatan. Based on ceramics from Sayil, this investigation seeks to expand exploration into the nature of commercialization during the Terminal Classic period (A.D. 800–1000). This research sought to: (a) establish the chemical composition of major Puuc wares, (b) begin to define potential raw materials and production loci at Sayil, and (c) explore the question of whether Sayil was a major producer and exporter of ceramic wares. Compositional analysis reveals that three of the four major Puuc wares (Puuc Slate, Puuc Unslipped, and Puuc Red) exhibit some degree of chemical distinctiveness, suggesting discrete production units. Compositional analysis of clays from Sayil and Loltun Cave indicates that Puuc Slate and Puuc Red Ware are compatible with clays locally available at Sayil, supporting local production of these wares, whereas Puuc Unslipped Ware initially appears to be closer compositionally to clays from Loltun. In addition, Puuc Slate is an important ware found throughout northern Yucatan that shows evidence of large-scale production at Sayil. This analysis represents the first steps of a comprehensive investigation into the Maya economy of Terminal Classic Yucatan.


2021 ◽  
Vol 75 (9) ◽  
pp. 752-756
Author(s):  
Jakob J. Mueller ◽  
Hans H. Wenk

Biosurfactants are surface-active molecules, developed by nature through evolution and naturally produced by different microorganisms. The most prominent examples are rhamnolipids and sophorolipids, molecules which contain hydrophilic sugar head groups and hydrophobic alkyl residues leading to an amphiphilic behavior with unique properties. Recent developments in the field of biotechnology enable the large-scale production of these biological molecules. The raw material basis is 100% renewable since sugars and oils are used as major raw materials. Additionally, biosurfactants are fully biodegradable, which allows the path back into the natural cycles. In comparison to established standard surfactants like SLES/SLS (sodium laureth (ether) sulfates) or betaines, rhamnolipids are much milder and, at the same time, show similar or even better performance in household or personal care applications. Foam behavior, solubilization and cleaning effectiveness are examples where these natural substances give excellent results compared to the synthetic benchmarks. The commercialization of biosurfactants at industrial scale now offers alternatives to consumers seeking sustainable solutions, without compromising performance. Biosurfactants combine both and set a new standard for surfactant applications.


RSC Advances ◽  
2014 ◽  
Vol 4 (108) ◽  
pp. 62965-62970 ◽  
Author(s):  
Jung Sang Cho ◽  
Kyeong Youl Jung ◽  
Mun Young Son ◽  
Yun Chan Kang

Dense spherical Y2O3:Eu3+ phosphor particles with a narrow size distribution were successfully prepared by using a two-step spray drying method. This method is easily scalable and can therefore be applied to the mass production of phosphor particles with high photoluminescence.


2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Sheelendra Mangal Bhatt ◽  
Anand Mohan ◽  
Suresh Kumar Srivastava

Mannitol is an important biochemical often used as medicine and in food sector, yet its biotechnological is not preffered in Industry for large scale production, which may be due to the multistep mechanism involved in hydrogenation and reduction. This paper is a comparative preview covering present chemical and biotechnological approaches existing today for mannitol production at industrial scale. Biotechnological routes are suitable for adaptation at industrial level for mannitol production, and whatever concerns are there had been discussed in detail, namely, raw materials, broad range of enzymes with high activity at elevated temperature suitable for use in reactor, cofactor limitation, reduced by-product formation, end product inhibition, and reduced utilization of mannitol for enhancing the yield with maximum volumetric productivity.


Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3387
Author(s):  
Enrique Niza ◽  
Alberto Ocaña ◽  
José Antonio Castro-Osma ◽  
Iván Bravo ◽  
Carlos Alonso-Moreno

Many therapeutic agents have failed in their clinical development, due to the toxic effects associated with non-transformed tissues. In this context, nanotechnology has been exploited to overcome such limitations, and also improve navigation across biological barriers. Amongst the many materials used in nanomedicine, with promising properties as therapeutic carriers, the following one stands out: biodegradable and biocompatible polymers. Polymeric nanoparticles are ideal candidates for drug delivery, given the versatility of raw materials and their feasibility in large-scale production. Furthermore, polymeric nanoparticles show great potential for easy surface modifications to optimize pharmacokinetics, including the half-life in circulation and targeted tissue delivery. Herein, we provide an overview of the current applications of polymeric nanoparticles as platforms in the development of novel nanomedicines for cancer treatment. In particular, we will focus on the raw materials that are widely used for polymeric nanoparticle generation, current methods for formulation, mechanism of action, and clinical investigations.


2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Anirban Nandi ◽  
Sharadwata Pan ◽  
Ravichandra Potumarthi ◽  
Michael K. Danquah ◽  
Indira P. Sarethy

Six Sigma methodology has been successfully applied to daily operations by several leading global private firms including GE and Motorola, to leverage their net profits. Comparatively, limited studies have been conducted to find out whether this highly successful methodology can be applied to research and development (R&D). In the current study, we have reviewed and proposed a process for a probable integration of Six Sigma methodology to large-scale production of Penicillin G and its subsequent conversion to 6-aminopenicillanic acid (6-APA). It is anticipated that the important aspects of quality control and quality assurance will highly benefit from the integration of Six Sigma methodology in mass production of Penicillin G and/or its conversion to 6-APA.


Author(s):  
Colin F. Baxter

One of the epic industrial and scientific achievements of the United States during World War II was accomplished at the Wexler Bend Pilot Plant, Kingsport, Tennessee, where fifty hand-picked (their finances were investigated, and all the operators were married with at least one child) Tennessee Eastman employees, working at a phenomenal pace, developed a process for large-scale production of the world’s most powerful explosive, RDX. The success at Wexler Bend opened the door to the next phase: the mass production of RDX.


2020 ◽  
Vol 10 (22) ◽  
pp. 8262
Author(s):  
Assadawoot Srikhaow ◽  
Teera Butburee ◽  
Weeraphat Pon-On ◽  
Toemsak Srikhirin ◽  
Kanchana Uraisin ◽  
...  

This work reports the preparation and utility of cysteine-functionalized carbon-coated Fe3O4 materials (Cys-C@Fe3O4) as efficient sorbents for remediation of Hg(II)-contaminated water. Efficient removal (90%) of Hg(II) from 1000 ppb aqueous solutions is possible, at very low Cys-C@Fe3O4 sorbent loadings (0.01 g sorbent per liter of Hg(II) solution). At low metal concentrations (5–100 ppb Hg(II)), where adsorption is typically slow, Hg(II) removal efficiencies of 94–99.4% were achievable, resulting in final Hg(II) levels of <1.0 ppb. From adsorption isotherms, the Hg(II) adsorption capacity for Cys-C@Fe3O4 is 94.33 mg g−1, around three times that of carbon-coated Fe3O4 material. The highest partition coefficient (PC) of 2312.5 mgg−1µM−1 was achieved at the initial Hg (II) concentration of 100 ppb, while significantly high PC values of 300 mgg−1µM−1 and above were also obtained in the ultralow concentration range (≤20 ppb). Cys-C@Fe3O4 exhibits excellent selectivity for Hg(II) when tested in the presence of Pb(II), Ni(II), and Cu(II) ions, is easily separable from aqueous media by application of an external magnet, and can be regenerated for three subsequent uses without compromising Hg(II) uptake. Derived from commercially available raw materials, it is highly possible to achieve large-scale production of the functional sorbent for practical applications.


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