scholarly journals Observational case studies of treatment of skin disorders with natural phages in Ganga water

2021 ◽  
Vol 12 (e) ◽  
pp. e77-e77
Author(s):  
Bharat Jhunjhunwala ◽  
Rakesh Kumar Bhatnagar ◽  
Ashutosh Shukla ◽  
Sanjay Kumar ◽  
Amit Patel ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Likert Scale ◽  
Environmental Engineering ◽  
Ganga River ◽  
Multiple Levels ◽  
Skin Conditions ◽  
National Environmental ◽  
Engineering Institute ◽  
Ganga Water ◽  
Multiple Causes

Background: Skin conditions have multiple causes. Natural phages in the Ganga River have bactericidal qualities against a number of bacterial infections, which help resolve skin conditions. Materials and Methods: We collected water from upper reaches of the Ganga River where the number of isolates of phages was more than 200 according to a study of the National Environmental Engineering Institute, Nagpur. The water was collected in May 2020 before the onset of monsoons and stored with sediments so that the phages adsorbed in the sediments cleaned up the overlaying column of water of all coliforms. We supplied the water by post to a number of volunteers who took the water through oral, topical or nasal route as per their convenience. Thirty-nine of the 52 volunteers provided data by telephone on their skin conditions on which this study is based. Results: The results show that an improvement of 1.7 on Likert Scale of 1-10 is obtained on skin conditions as per assessment of the volunteers after a treatment of 100 days. Further improvement of 1.0 on Likert Scale was reported after 85 days of stoppage of treatment. Conclusions: Natural phages of Ganga river could provide an inexpensive treatment not only for skin conditions but other comorbidities as well because skin conditions have multiple causes and phages of Ganga water may work at multiple levels.

scholarly journals Observational case studies of the effect of phage laden Ganga water on psoriasis

2021 ◽  
Vol 7 (3) ◽  
pp. 186-190
Author(s):  
Bharat Jhunjhunwala ◽  
Ranjana Waghralkar
Keyword(s):  
Case Studies ◽  
Phage Therapy ◽  
Ganga River ◽  
Large Numbers ◽  
Pre Treatment ◽  
Number Of Bacteria ◽  
Ganga Water ◽  
Robust Protocol ◽  
Multiple Causes

Water of Ganga river is reported to have more than 200 isolates of phages. This study has used the naturally available cocktail of phages in the Ganga water as a treatment for chronic Psoriasis. In the conventional Phage Therapy (PT) phages that are active against specific bacteria are first identified; then isolated, multiplied and administered to the patient. We have made a novel innovation of administering the naturally available cocktail of phages in the water of the Ganga river without first identifying the target bacteria and isolating specific phages that may be active against them. In doing so, we enable the large numbers of phages to self-identify the bacteria that are present and act against them. This approach shortcuts the tortuous process of conventional PT. Further, the phages act against a number of bacteria simultaneously and provide good results in psoriasis which has multiple causes.Patients who took Ganga water for only 2 weeks showed benefit but the benefit did not sustain after stoppage of the treatment and the disease relapsed to the pre-treatment levels. The same patients showed sustained benefit after they took Ganga water for four weeks. Conclusion is that Ganga water can be used for therapeutic purposes as long as the treatment is continued for at least four weeks. The study underscores the need to establish more robust protocol for treatment of dermatological and possibly other diseases with the cocktail of phages available in the waters of the Ganga river.

Crusts, scabs, and eschars

2020 ◽  
pp. 393-402
Keyword(s):  
Bacterial Infections ◽  
Tinea Capitis ◽  
Viral Infections ◽  
Skin Diseases ◽  
Systemic Disease ◽  
Clinical Images ◽  
Pityriasis Lichenoides ◽  
Appropriate Treatment ◽  
Bites And Stings ◽  
Skin Conditions

Definitions and clinical images are used in this short chapter to permit differentiation between crusts, scabs, and eschars and their likely causes. These are listed as skin infections, trauma, or skin conditions such as eczema or blistering disorders. There are brief descriptions with appropriate treatment and there is cross-referencing to other chapters. Short summaries of diseases causing eschars are provided. These include bacterial infections (e.g. ecthyma, anthrax), viral infections (e.g. cowpox, orf), fungal (e.g. Tinea capitis), and protozoal (e.g. Leishmaniasis) conditions. Also included are skin diseases such as pityriasis lichenoides, toxins/allergens (from various bites and stings), and systemic disease such as autoimmune vasculitis, haematological disorders, or tumours.

Nanocrystalline chloroxine possesses broad-spectrum antimicrobial activities and excellent skin tolerability in mice

Nanomedicine ◽  
2022 ◽  
Author(s):  
Jiří Trousil ◽  
Jana Matějková ◽  
You-Shan Dai ◽  
Tomáš Urbánek ◽  
Miroslav Šlouf ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Skin Irritation ◽  
Antimicrobial Activities ◽  
Great Promise ◽  
Good Tolerability ◽  
Wide Range ◽  
Skin Tolerability ◽  
Skin Conditions ◽  
Bacteria And Fungi

Background: Antimicrobial submicrometer particles are being studied as promising interventions against a wide range of skin conditions, such as fungal or bacterial infections. Aims: To submicronize chloroxine, the crystalline compound 5,7-dichloro-8-hydroxyquinoline, by nanoprecipitation and characterize the resulting assemblies. Methods: The chloroxine particles were stabilized by a nonionic surfactant and were studied by a broth microdilution assay against 20 medically important bacteria and fungi. The intervention was studied using a murine model of skin irritation. Results & conclusions: Chloroxine nanoparticles with a diameter of 600–800 nm exhibit good tolerability in terms of skin irritation in vivo and good antimicrobial activity. Thus, the fabricated formulation shows great promise for interventions for both cutaneous infection control and prophylaxis.

Sethusamudram Shipping Canal Project: In Need of Divine Intervention

2014 ◽  
pp. 1-31
Author(s):  
Chandrasekaran K ◽  
Sachin Bhardwaj ◽  
Shipra Jain ◽  
Rohit Singh Sahani ◽  
Akansha Baliga ◽  
...  
Keyword(s):  
Supreme Court ◽  
Decision Makers ◽  
Environmental Engineering ◽  
Engineering Research ◽  
Project Report ◽  
Divine Intervention ◽  
The Supreme Court ◽  
Infrastructure Project ◽  
The Impact ◽  
National Environmental

The case looks at the Sethusamudram Shipping Canal Project from its inception in the year 1860 to 2012 when the Pachauri Committee was about to submit a report on the latest canal alignment (4A) as suggested by the Supreme Court. It takes the reader through a series of developments starting from the initial proposals and alignments to formation of Sethusamudram Corporation Limited and highlights the impact of National Environmental Engineering Research Institute Report, Tsunami Detailed Project Report, and Subramaniam Swamy Report on various issues including environmental, political, religious, security and legal. The case brings out multi-dimensional aspects involved in an Indian infrastructure project and gives both students and the faculty an opportunity to explore the complexities faced by the Indian decision makers in today's context.

scholarly journals HOUSEHOLD WASTE BIOREACTOR MODIFICATION BASE ON ANAEROBIC DECOMPOSITION

2018 ◽  
Author(s):  
Anita Dewi Moelyaningrum
Keyword(s):  
Urban Communities ◽  
Organic Waste ◽  
Ph Value ◽  
Environmental Engineering ◽  
Household Waste ◽  
Kitchen Waste ◽  
Compost Quality ◽  
Micro Organisms ◽  
Engineering Institute ◽  
Effective Microorganism

Proceeding The 4thInternational seminar of Environmental Engineering 2013Advances in Sustainable Environmental Resource Management and Sanitation Technology. June 2013Page: 403-411Department of Environmental Engineering, Institute Teknologi Sepuluh Nopember, IndonesiaISBN 978-602-95595-6-9The waste volume in Indonesia was 490.000 ton/ day or 178.850.000 ton/ year, Which 50% was household waste (Ministry of Environment of Indonesia, 2012). Anaerobic composting not as popular as aerobic composting in Indonesia. Anaerobic composting is very simple, it doesn`t need turning, watering etc to decompose waste. The objective of this research is to design bioreactor modification and analyze the compost quality and the effectiveness to reduce waste, so it suitable for urban communities to composting their waste. Anaerobic and aerobic bioreactor modification was design by plastic mineral drinking water 19 litter. The row organic materials are 3 kg kitchen waste, fruits waste 1 kg (bioreactor anaerobic 1 and aerobic 3) and 3 kg Kitchen waste, fruits waste 1 kg, added inoculation of micro-organisms as Effective Microorganism (EM4) in 1 cc/ 500 ml water (Bioreactor anaerobic 2 and aerobic 4 ). Temperature the row material at 20.2°C (Bioreactor 1 and 3) and at 25°C (Bioreactor 2 and 4); pH value at 4.3 (Bioreactor 1 and 3) and 5.5 (Bioreactor 2 and 4); moisture at 86.3 (Bioreactor 1 and 3) and 80.1 (Bioreactor 2 and 4); carbon into Nitrogen ratios (C/N) at 23.4 (Bioreactor 1 and 3) and 18.53 (Bioreactor 2 and 4). Monitoring temperature and pH value are shown at 20°C and 6.0 (Bioreactor 3) and at 2.2 °C and 6.7 (Bioreactor 4). Compost Quality appropriate with Indonesia compost Standart (SNI 19-7030-2004). Anaerobic bioreactor modification can reduce organic waste bigger than aerobic bioreactor modification. It is a recommendation to applying to the urban community because of simple, no need turning, watering etc and effective to reduce waste.

scholarly journals The perceptions of parents about the skin conditions of their children presenting with comorbid fungal skin infections in Francistown, Botswana

2013 ◽  
Vol 5 (1) ◽  
Author(s):  
Deciderius C. Ifebuzor ◽  
Langalibalele H. Mabuza ◽  
Nomsa H. Malete ◽  
Indiran Govender
Keyword(s):  
Health Care ◽  
Skin Condition ◽  
City Council ◽  
Skin Infections ◽  
Health Care Practitioners ◽  
Home Remedies ◽  
Skin Conditions ◽  
Multiple Causes

Background: In 2006, about 50% of the children whose parents brought them to the Francistown City Council clinics in Botswana for consultation had fungal skin infections. Most of these parents did not include the fungal skin conditions in the list of presenting complaints.Objective: To explore the perceptions of the parents about the fungal skin conditions of their children.Method: Eight participants were purposefully selected amongst the Francistown City Council clinics. They were interviewed, using the same exploratory question: ‘How much doyou know about this skin condition?’ The Setswana translation is: ‘O itse go le kae ka bolwetsijone jo jwa letlalo?’ The interviews were held in the Setswana language and audiotaped. The recordings were transcribed verbatim and translated into English. The ideas that emerged were developed into themes through the ‘cut-and-paste’ method.Results: The following themes emerged: the skin condition was not well-understood, it was perceived to have multiple causes, it was known to be infectious, many home remedies were used to attempt to cure it, it was not serious enough to warrant consultation and it tends to recur.Conclusion: Parents who brought their children to the Francistown City Council clinics in Botswana with fungal skin infections (incidentally discovered by the health care practitioners)perceived the skin infections as normal and not serious enough to be mentioned in a consultation. It is recommended that health care practitioners proactively educate parents of children presenting with comorbid fungal skin infections.

Particle characterization of CVD tungsten metallization for 64 MBIT DRAM

1991 ◽  
Vol 49 ◽  
pp. 896-897
Author(s):  
Marylyn Bennett-Lilley ◽  
Thomas T.H. Fu ◽  
David D. Yin ◽  
R. Allen Bowling
Keyword(s):  
Chemical Vapor ◽  
Device Performance ◽  
Particle Characterization ◽  
Particle Generation ◽  
Tungsten Hexafluoride ◽  
Homogeneous Particle ◽  
Multiple Levels ◽  
Circuit Density ◽  
Sources Of Contamination

Chemical Vapor Deposition (CVD) tungsten metallization is used to increase VLSI device performance due to its low resistivity, and improved reliability over other metallization schemes. Because of its conformal nature as a blanket film, CVD-W has been adapted to multiple levels of metal which increases circuit density. It has been used to fabricate 16 MBIT DRAM technology in a manufacturing environment, and is the metallization for 64 MBIT DRAM technology currently under development. In this work, we investigate some sources of contamination. One possible source of contamination is impurities in the feed tungsten hexafluoride (WF6) gas. Another is particle generation from the various reactor components. Another generation source is homogeneous particle generation of particles from the WF6 gas itself. The purpose of this work is to investigate and analyze CVD-W process-generated particles, and establish a particle characterization methodology.

Intrahepatic Retention of Bile in Severe Bacterial Infections

1964 ◽  
Vol 47 (6) ◽  
pp. 590-599 ◽  
Author(s):  
H. Fahrländer ◽  
F. Huber ◽  
F. Gloor
Keyword(s):  
Bacterial Infections
Sign in / Sign up

Export Citation Format

Share Document