scholarly journals Survival Outcomes of Recurrent Epithelial Ovarian Cancer: Experience from a Thailand Northern Tertiary Care Center

2015 ◽  
Vol 15 (24) ◽  
pp. 10837-10840 ◽  
Author(s):  
Natpat Jansaka ◽  
Prapaporn Suprasert
2021 ◽  
Vol 39 (6_suppl) ◽  
pp. 4-4
Author(s):  
VIKAS GARG ◽  
Mukurdipi Ray ◽  
KP Haresh ◽  
Ranjit Kumar Sahoo ◽  
Atul Sharma ◽  
...  

4 Background: Rural residence, educational status & longer travel distance are variably associated with suboptimal cancer treatment and outcomes. There are limited data on impact of these factors on treatment patterns & survival outcomes in penile cancer. Methods: Patients with a histological diagnosis of carcinoma penis during 2015 to 2019 were identified from the database of a large tertiary care center in India. Chart reviews were performed to retrieve demographic, clinicopathological and treatment details. Educational status was categorized as no formal education and any educational attainment, while travel distance was dichotomized at 500 km. Logistic regression analyses were performed to examine the associations with cancer treatments. Relapse free survival (RS) and overall survival (OS) were calculated by plotting Kaplan Meir curves and compared using log rank test. Multivariable Cox regression analysis were used to determine the associations of socioeconomic status and residence on survival outcomes. Results: A total of 100 patients were eligible for the current analysis. The median age was 56 (interquartile [IQR]range, 42-65) years. The median duration of symptoms was 6 (IQR, 4-12) months. Ulcero-proliferative growth (65%) was the most common presenting symptom followed by pain (57%) and dysuria (36%). Most patients had grade 2 tumor (60%), while stage was equally distributed from I-IV. Three-fourths of patients had clinically enlarged inguinal lymph nodes, while, 42 % were pathologically involved. Of all patients, 58% were from rural communities, 44% patient didn’t receive any formal education, and 36% had travelling distance of over 500 km from the hospital. Surgery, radiotherapy, and chemotherapy were administered in 53%, 42% and 24%, respectively. On multivariable logistic regression analysis, lower education, rural residence and longer travel distance were not associated with a lower likelihood of receiving any treatment. At a median follow-up of 50.7 months, median RFS and OS were 59.8 (95% CI, 15.8-NR) and 83.9 (95% CI, 29.2–NR) months, respectively. After adjusting for tumor stage, involvement of lymph nodes, PS, and grade, education status, primary residence (urban vs rural), and distance from the treatment center were not associated with RFS and OS. However, advanced stage was the only factor predictive of worse RFS and OS (Table). Conclusions: Rural residence, educational status and travel time were not associated with treatment administration and survival outcomes in patients with penile cancer treated in a publicly funded tertiary care center in India. [Table: see text]


2021 ◽  
Author(s):  
David Atallah ◽  
Wissam Arab ◽  
Bruno Dagher ◽  
Nour Khalil ◽  
Elsa El Rawadi ◽  
...  

Aim: To determine the rate, repartition and risk factors of lymph node (LN) metastasis in patients with epithelial ovarian cancer. Methods: We reviewed retrospectively the pathological and clinical data of 184 patients with epithelial ovarian cancer at a tertiary care center in Beirut, Lebanon. Results: 88% of patients received a pelvic and para-aortic lymphadenectomy. 70% of patients presented LN metastases at both pelvic and para-aortic levels, while isolated pelvic or para-aortic LN metastases were seen in 16 and 14% of cases, respectively. In a univariate analysis, the rate of positive LNs was higher in patients with serous histology (65 vs 33%; p < 0.001), high-grade tumors (68 vs 26%; p < 0.001), bilateral adnexal involvement (74 vs 27%; p < 0.001), advanced clinical stage (p < 0.001), interval debulking surgery (63.2 vs 36.8%; p = 0.003) and positive peritoneal cytology (79 vs 26%; p < 0.001). In a multivariate analysis, the rate of LN involvement was significantly higher in patients with higher grade, advanced clinical stage and positive peritoneal cytology. Conclusion: Serous histology, grade 3 tumors, positive peritoneal cytology, advanced clinical stage, interval surgery and bilateral adnexal involvement can predict LN metastasis in patients with epithelial ovarian cancer.


2019 ◽  
Vol 10 (2) ◽  
pp. 365-367
Author(s):  
Tarek Assi ◽  
Ziad Bakouny ◽  
Chris Labaki ◽  
Elie El Rassy ◽  
Aline Khazzaka ◽  
...  

Oral Oncology ◽  
2021 ◽  
Vol 118 ◽  
pp. 2
Author(s):  
André Laranja ◽  
Diana Moreira ◽  
Isabel Reis ◽  
Isabel Rodrigues ◽  
Fausto Sousa ◽  
...  

2009 ◽  
Vol 27 (2) ◽  
pp. 233-236 ◽  
Author(s):  
V. M. Pérez-Sánchez ◽  
T. A. Vela-Chávez ◽  
P. Villarreal-Colin ◽  
E. Bargalló-Rocha ◽  
M. T. Ramírez-Ugalde ◽  
...  

2017 ◽  
Vol 80 (5) ◽  
pp. 474-478 ◽  
Author(s):  
Rahul Khanna ◽  
Ram Niwas Meena ◽  
Akash Bansal ◽  
S. C. U. Patne ◽  
Shashi Prakash Mishra ◽  
...  

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Renu Madan ◽  
Chinna Babu Dracham ◽  
Arun Elangovan ◽  
Bhavana Rai ◽  
G. Y. Srinivasa ◽  
...  

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