scholarly journals Disparate substrates for head gaze following and face perception in the monkey superior temporal sulcus

eLife ◽  
2014 ◽  
Vol 3 ◽  
Author(s):  
Karolina Marciniak ◽  
Artin Atabaki ◽  
Peter W Dicke ◽  
Peter Thier

Primates use gaze cues to follow peer gaze to an object of joint attention. Gaze following of monkeys is largely determined by head or face orientation. We used fMRI in rhesus monkeys to identify brain regions underlying head gaze following and to assess their relationship to the ‘face patch’ system, the latter being the likely source of information on face orientation. We trained monkeys to locate targets by either following head gaze or using a learned association of face identity with the same targets. Head gaze following activated a distinct region in the posterior STS, close to-albeit not overlapping with-the medial face patch delineated by passive viewing of faces. This ‘gaze following patch’ may be the substrate of the geometrical calculations needed to translate information on head orientation from the face patches into precise shifts of attention, taking the spatial relationship of the two interacting agents into account.

Author(s):  
Ruth V.W. Dimlich

Mast cells in the dura mater of the rat may play a role in cerebral pathologies including neurogenic inflammation (vasodilation; plasma extravasation) and headache pain . As has been suggested for other tissues, dural mast cells may exhibit a close spatial relationship to nerves. There has been no detailed ultrastructural description of mast cells in this tissue; therefore, the goals of this study were to provide this analysis and to determine the spatial relationship of mast cells to nerves and other components of the dura mater in the rat.Four adult anesthetized male Wistar rats (290-400 g) were fixed by perfusion through the heart with 2% glutaraldehyde and 2.8% paraformaldehyde in a potassium phosphate buffer (pH 7.4) for 30 min. The head of each rat was removed and stored in fixative for a minimum of 24 h at which time the dural coverings were removed and dissected into samples that included the middle meningeal vasculature. Samples were routinely processed and flat embedded in LX 112. Thick (1 um) sections from a minimum of 3 blocks per rat were stained with toluidine blue (0.5% aqueous).


2014 ◽  
Vol 28 (3) ◽  
pp. 148-161 ◽  
Author(s):  
David Friedman ◽  
Ray Johnson

A cardinal feature of aging is a decline in episodic memory (EM). Nevertheless, there is evidence that some older adults may be able to “compensate” for failures in recollection-based processing by recruiting brain regions and cognitive processes not normally recruited by the young. We review the evidence suggesting that age-related declines in EM performance and recollection-related brain activity (left-parietal EM effect; LPEM) are due to altered processing at encoding. We describe results from our laboratory on differences in encoding- and retrieval-related activity between young and older adults. We then show that, relative to the young, in older adults brain activity at encoding is reduced over a brain region believed to be crucial for successful semantic elaboration in a 400–1,400-ms interval (left inferior prefrontal cortex, LIPFC; Johnson, Nessler, & Friedman, 2013 ; Nessler, Friedman, Johnson, & Bersick, 2007 ; Nessler, Johnson, Bersick, & Friedman, 2006 ). This reduced brain activity is associated with diminished subsequent recognition-memory performance and the LPEM at retrieval. We provide evidence for this premise by demonstrating that disrupting encoding-related processes during this 400–1,400-ms interval in young adults affords causal support for the hypothesis that the reduction over LIPFC during encoding produces the hallmarks of an age-related EM deficit: normal semantic retrieval at encoding, reduced subsequent episodic recognition accuracy, free recall, and the LPEM. Finally, we show that the reduced LPEM in young adults is associated with “additional” brain activity over similar brain areas as those activated when older adults show deficient retrieval. Hence, rather than supporting the compensation hypothesis, these data are more consistent with the scaffolding hypothesis, in which the recruitment of additional cognitive processes is an adaptive response across the life span in the face of momentary increases in task demand due to poorly-encoded episodic memories.


2020 ◽  
Vol 36 (03) ◽  
pp. 309-316
Author(s):  
Ozcan Cakmak ◽  
Ismet Emrah Emre

AbstractPreservation of the facial nerve is crucial in any type of facial procedure. This is even more important when performing plastic surgery on the face. An intricate knowledge of the course of the facial nerve is a requisite prior to performing facelifts, regardless of the technique used. The complex relationship of the ligaments and the facial nerve may put the nerve at an increased risk of damage, especially if its anatomy is not fully understood. There are several danger zones during dissection where the nerve is more likely to be injured. These include the areas where the nerve branches become more superficial in the dissection plane, and where they traverse between the retaining ligaments of the face. Addressing these ligaments is crucial, as they prevent the transmission of traction during facelifts. Without sufficient release, a satisfying pull on the soft tissues may be limited. Traditional superficial musculoaponeurotic system techniques such as plication or imbrication do not include surgical release of these attachments. Extended facelift techniques include additional dissection to release the retaining ligaments to obtain a more balanced and healthier look. However, these techniques are often the subject of much debate due to the extended dissection that carries a higher risk of nerve complications. In this article we aim to present the relationship of both the nerve and ligaments with an emphasis on the exact location of these structures, both in regard to one another and to their locations within the facial soft tissues, to perform extended techniques safely.


2021 ◽  
Vol 10 (7) ◽  
pp. 432
Author(s):  
Nicolai Moos ◽  
Carsten Juergens ◽  
Andreas P. Redecker

This paper describes a methodological approach that is able to analyse socio-demographic and -economic data in large-scale spatial detail. Based on the two variables, population density and annual income, one investigates the spatial relationship of these variables to identify locations of imbalance or disparities assisted by bivariate choropleth maps. The aim is to gain a deeper insight into spatial components of socioeconomic nexuses, such as the relationships between the two variables, especially for high-resolution spatial units. The used methodology is able to assist political decision-making, target group advertising in the field of geo-marketing and for the site searches of new shop locations, as well as further socioeconomic research and urban planning. The developed methodology was tested in a national case study in Germany and is easily transferrable to other countries with comparable datasets. The analysis was carried out utilising data about population density and average annual income linked to spatially referenced polygons of postal codes. These were disaggregated initially via a readapted three-class dasymetric mapping approach and allocated to large-scale city block polygons. Univariate and bivariate choropleth maps generated from the resulting datasets were then used to identify and compare spatial economic disparities for a study area in North Rhine-Westphalia (NRW), Germany. Subsequently, based on these variables, a multivariate clustering approach was conducted for a demonstration area in Dortmund. In the result, it was obvious that the spatially disaggregated data allow more detailed insight into spatial patterns of socioeconomic attributes than the coarser data related to postal code polygons.


Neurosurgery ◽  
1988 ◽  
Vol 23 (6) ◽  
pp. 770-773 ◽  
Author(s):  
Masahiko Udzura ◽  
Hiroo Kobayashi ◽  
Yoshio Taguchi ◽  
Hiroaki Sekino

Abstract A 54-year-old man with a right hemiparesis was found to have an intrasellar intercarotid communicating artery associated with agenesis of the right internal carotid artery. Magnetic resonance imaging (MRI) studies demonstrated the spatial relationship of the anomalous artery to the surrounding structures, thus suggesting an embryonic enlargement of the capsular artery as a source of this anomalous artery.


2000 ◽  
Vol 12 (1-4) ◽  
pp. 141-161
Author(s):  
Robert N. Mccauley

AbstractThe aims of this paper are to identify three barriers to the development of cognitive approaches to the study of religion and to suggest how each might be circumvented. The first of these barriers is methodological and lurks amid two issues that, historically, have dominated anthropologists' reflections on the relationship of their discipline to psychology. The older of the two can be characterized as the "psychic unity" controversy (see Shore 1995). The second issue is the controversy over the "autonomy of culture". Advocates of the latter thesis are usually unsympathetic to psychological explanations of religious phenomena. In the first section, I shall begin by briefly examining each of those issues and then exploring the connections between the two as well as interesting logical tensions that arise in the face of popular responses to each. In section two, I shall consider a pair of barriers to a cognitive psychology of religion rooted in two strategies that have dominated many psychologists' approaches to the study of religion. I will argue that for some purposes, at least, both strategies should be relaxed. Finally, in section three, I shall briefly sketch one sort of cognitive approach to religious phenomena, suggesting how it handles the two strategic barriers in particular.


2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Larissa Fonseca

Sinopse: Em meio ao colorido de goiabas, batatas e flores mais que cheiros e sabores, descobrir pessoas. Agricultoras e agricultores que com suas histórias e lutas, estão representados nas varandas e nas mesas da cidade. Trazer a imagem não de uma feira, mas de cada pessoa que diariamente se dedica ao cultivo e à produção de alimentos. Encontrar o rosto e as escolhas de outros modos de fazer agricultura, de outros modos de se alimentar. De assentados e suas lutas pela preservação de sementes crioulas, de jovens universitários e sua determinação em permanecer no campo e de fumicultores aposentados dispostos a limpar suas terras dos venenos de mais 30 anos de cultivos agressivos, é feita a Feira Sabores da Terra. Feira da agricultura familiar do município de Canguçu, Rio Grande do Sul, que acontece todas as segundas-feiras à tarde e reúne cerca de 18 produtores. Em um pavilhão de madeira no centro da cidade são expostos doces coloniais, panificados, frangos congelados, farinhas, feijões, legumes, verduras, frutas e flores, em variedade conforme a estação do ano. Produtos que são vendidos entre boas conversas, rodas de chimarrão e é claro, uma melancia bem gelada ou uma deliciosa rapadura. Para a permanência e continuação da feira, que se realiza há pouco mais de um ano, os feirantes têm enfrentado e superado dificuldades. A distância de suas propriedades até a cidade, muitas das vezes são mais do que duas horas de viagem. A demanda, pelos consumidores, por produtos conforme padrões estéticos dos alimentos produzidos com veneno. O cansaço de mãos que, com mais de 40 anos de trabalho, ainda enfrentam a roça durante toda a semana e o frio, a chuva e o calor de uma feira praticamente ao ar livre. O conciliar o trabalho agrícola e a feira com os estudos, cujo acesso limitado pela distância das universidades, das oportunidades de estágios e pela dificuldade de ascender ao ensino público superior. Apesar de tão próximos, rostos e mãos muitas vezes invisíveis em escolhas alimentares. Gente que oportuniza uma alternativa à alimentação. Alimentação proveniente da relação de mulheres e homens com a terra, de suas sabedorias e ações. Feira Sabores da Terra, um ponto de aproximação entre o campo e a cidade, entre o cultivo e o alimento, entre o cuidado e o sabor. De agricultoras e agricultores e seus feijões, morangos e biscoitos. Este ensaio fotográfico é parte da agenda de pesquisa “Saberes e Sabores da Colônia”, desenvolvida no âmbito do Grupo de Estudos e Pesquisas em Alimentação e Cultura (GEPAC) e vinculada ao Bacharelado e ao Programa de Pós-Graduação em Antropologia da Universidade Federal de Pelotas. Synopsis: In the middle of colored places with guava , potatoes and flowers more than smells of flavors, we discover people. Farmers, with your stories and struggles, are represented on the balconies and tables of the city. Representing the image of each person that daily is dedicated to the cultivation and food production, not just the image of a fair is much more than that. Find the face and choices of other ways of doing agriculture and others ways of feeding. From the land reform settlements and their struggles for the preservation of native seeds, of university students and their determination to remain in the field and retires tobacco growers willing to clear their land of the poisons of another 30 years of aggressive crops, is made the Flavors of the Earth Fair. Family Agriculture Fair, in the Canguçu City in Rio Grande do Sul, Brazil, of what happens on every Monday afternoon and brings together about 18 small farmers. In a wooden pavilion in Downtown city are exposed colonial sweets, bakery products, quick-frozen, flours, beans, vegetables, fruits and flowers in variety according to season. Products that are sold as God´s taste is of course chimarrão, and watermelon ice-cold or a delicious rapadura. For the permanence and continuation of the green fair, been held little more than a year ago, the small farmers have had and overcome difficulties. The distance of their properties of the Downtown , often last more than two hours of the trip. The consumer demand by products according to aesthetic standards of foods produced with venom. The fatigue of hands, still for more than 40 years of work, are still facing small farm during the days in a cool, rain and heat weather and the a fair still open. To reconcile agricultural work and the fair with studies, to which access is restricted by distances from universities, internship opportunities, and the difficulty of access to higher public education. Although close, often invisible faces and hands in food choices. People who offer alternative food. Food derived from the relationship of men and women to the land, of his wisdom and actions. Flavors of The Hearth Fair, a point of approximation between the countryside and the city, between the crop and the food, between care and taste. Of farmers and agriculturists and their beans, strawberries and biscuits. This photo essay is part of research agenda “Knowledge and tastes of the agricultural colony”, developed in the framework of the Group of the Studies and Researches in Food an Culture (GEPAC) and linked to the Bachelor’s and the Postgraduate Program In Anthropology of Federal University of Pelotas. Palavras-chave: Agricultura Familiar – Campesinato – Feira – Alimentação - Consumo Key-words: : Family Agriculture - Peasantry – Fair – Food - Consumption Ficha técnica: Direção: Larissa Fonseca Roteiro: Larissa Fonseca Fotografia: Larissa Fonseca Coordenação de Pesquisa: Renata Menasche Edição de Imagem: Larissa Fonseca e Hamilton Bittencourt Assessoria em Imagem: Claudia Turra Magni Credits: Author: Larissa Fonseca Photographs: Larissa Fonseca Direction: Larissa Fonseca Research Coordination: Renata Menasche Image Editing: Larissa Fonseca e Hamilton Bittencourt Image Consulting: Claudia Turra Magni.


Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000012025
Author(s):  
Shahram Oveisgharan ◽  
Ana W. Capuano ◽  
Sukriti Nag ◽  
Sonal Agrawal ◽  
Lisa L. Barnes ◽  
...  

Objective.We tested the hypothesis that an inverse association exists between diabetes mellitus (DM) and hemoglobin A1C (A1C) with Transactive response DNA binding protein 43 (TDP-43) levels in older adults.Methods.We leveraged antemortem and postmortem data of decedents from three community-based clinical-pathological studies. DM status, A1C levels, and medications for DM were documented annually. TDP-43 cytoplasmic inclusions, evaluated in 6 brain regions using immunohistochemistry, were used to obtain a semiquantitative TDP-43 score (0-5) in each region, and scores were averaged across regions to obtain a TDP-43 severity score. We used linear regressions to test the association of DM and A1C with the TDP-43 severity score.Results.On average, participants (n=817) were 90 years old at the time of death, three fourth were women, and one fourth had DM. The mean A1C was 6.0% (SD=0.6). TDP-43 was observed in 54% of participants, and the mean TDP-43 score was 0.7 (range 0-4.5). A higher level of A1C was associated with a lower TDP-43 score (estimate=-0.156, S.E.=0.060, p=0.009) while DM had a borderline inverse association with the TDP-43 score (estimate=-0.163, S.E.=0.087, p=0.060). The association of higher levels of A1C with lower TDP-43 scores persisted after further adjustment by Apolipoprotein ε4, vascular risk factors, stroke, and hypoglycemic medications. Exclusion of the oldest old participants did not change the results.Conclusion.Overall, the results suggest that a high level of A1C is associated with less TDP-43 proteinopathy in older persons while the relationship of DM with TDP-43 needs further study.


2018 ◽  
Vol 14 (1) ◽  
pp. 81-95 ◽  
Author(s):  
Indrit Bègue ◽  
Maarten Vaessen ◽  
Jeremy Hofmeister ◽  
Marice Pereira ◽  
Sophie Schwartz ◽  
...  

2012 ◽  
Vol 130 ◽  
pp. 42
Author(s):  
Mohammed Alghoul ◽  
Ozan Bitik ◽  
Jennifer McBride ◽  
James E. Zins

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