scholarly journals Survey of Relation between Midcycle Progesterone Level with IUI Cycles Success Rate

2020 ◽  
Vol 7 (4) ◽  
pp. 9
Author(s):  
Alieh Ghasemzadeh ◽  
Gilda Mostafavi ◽  
Mohammad Nouri ◽  
Parastoo Chaichi ◽  
Laya Farzadi ◽  
...  
Keyword(s):  
Success Rate ◽  
Pregnancy Rate ◽  
Assisted Reproductive Technology ◽  
Endometrial Thickness ◽  
Cross Sectional Study ◽  
Reproductive Technology ◽  
Clinical Pregnancy ◽  
Progesterone Level ◽  
Sectional Study ◽  
Cross Sectional

Introduction: Assisted reproductive technology is used routinely for treatment of infertile spouses. Previous studies reported conflicting results regarding effect of progesterone rise at the HCG injection day. The aim of current study is to evaluate the effects of mid cycle progesterone levels in IUI cycles. Methods: In this analytical cross-sectional study, the outcome of treatment in 200 IUI cycles were evaluated. Patients’ demographic findings, progesterone level at the day of HCG injection, number of follicles >16 mm, endometrial thickness and clinical pregnancy rate were recorded. For better evaluation, progesterone levels were divided to <0.5, 0.5-1.5 and >1.5 ng/dl. Results: Patients’ mean age was 29.70±4.38 years. The progesterone levels of <0.5, 0.5-1.5 and >1.5 ng/dl was detected in 24.5%, 56% and 19.5% of patients, respectively. The rate of clinical pregnancy was 27.5%. Cases with positive pregnancy had significantly lower progesterone levels (0.88±0.31 vs.1.11±0.80, p=0.04). The highest pregnancy rate was in progesterone levels 0.5-1.5 compared to levels <0.5 and >1.5 ng/dl (42% vs. 12.2% vs. 5.2%, p<0.001). There was no significant correlation between progesterone levels with endometrial thickness (r=-0.130, p=0.06) and number of follicles >16 mm(r=0.02, p=0.77). Conclusion: The results of current study showed that the increase in progesterone levels at the day of HCG injection accompanies with lower pregnancy rate. However, this increase has no correlation with number of mature follicles and endometrial thickness.

scholarly journals The Association Between Serum Estradiol and Progesterone On the Same Day of FET and The Pregnancy Outcome; A Cross Sectional Study

2021 ◽  
Vol 6 (2) ◽  
Keyword(s):  
Pregnancy Rate ◽  
Pregnancy Outcome ◽  
Endometrial Thickness ◽  
Research Question ◽  
Cross Sectional Study ◽  
Clinical Pregnancy ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Impact

Research Question Precise timed synchronization between endometrium and the embryo is essential for high implantation and pregnancy rate, it is worthy to mention that endometrial thickness is not the only factor, E2 and P levels are also regularly monitored for endometrial receptivity. So, we decided to go for this study, to investigate the impact of serum E2 and P levels on the same day of embryo transfer on pregnancy outcomes for FET cycles. Design This was a retrospective cross sectional study for 402 FET cycles which conducted between April 2018 and May 2019. All participants started endometrial preparation for FET with 6 mg/day oral estradiol for 13 days. When endometrium reached 8 mm or greater, patients were initiated on both micronized vaginal and oral P treatment. On FET day, serum level of E2 and P were assessed. Then, transfer of PGT euploid embryos was performed. 12 days’ later pregnancy test was assessed, and then 4 weeks after FET date ultrasound was scheduled to check the viability and the clinical pregnancy. Results The mean E2 value was 931.41 ± 438.65 pg/ml, while mean P value was 8.47 ± 9.4 ng/ml. 240 out of 402 cases got pregnant (59.7%) while the clinical pregnancy rate was 53.9% with no correlation between serum (E2, P & E/P ratio) and the outcome. Conclusion Our results revealed that the association between E2 and P on FET day and the pregnancy outcome is still not proven and those markers can’t serve as predictors for the outcome.

Psychotropic medication use among women seeking assisted reproductive technology (ART) therapy: a cross-sectional study

2021 ◽  
Author(s):  
Claudia F. Carvalho ◽  
Marília Meneghel Colla Mattia ◽  
Helena da Silva ◽  
Frederico Guilherme Flores Soares Bredemeier ◽  
Nicolas Endrigo Arpini ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Art Therapy ◽  
Psychotropic Medication ◽  
Medication Use ◽  
Cross Sectional Study ◽  
Reproductive Technology ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals The effect of seasonality on reproductive outcome of patients undergoing intracytoplasmic sperm injection: A descriptive cross-sectional study

2020 ◽  
Author(s):  
Marzieh Mehrafza ◽  
Maryam Asgharnia ◽  
Azadeh Raoufi ◽  
Elmira Hosseinzadeh ◽  
Sajedeh Samadnia ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Pregnancy Outcome ◽  
Intracytoplasmic Sperm Injection ◽  
Cross Sectional Study ◽  
Reproductive Technology ◽  
Seasonal Effect ◽  
Medical Institute ◽  
Sectional Study ◽  
Cross Sectional ◽  
Injection Cycle

Background: There is conflicting evidence regarding the impact of season on the assisted reproductive technology outcome. Objective: To retrospectively compare three year outcome of women undergoing their first intracytoplasmic sperm injection cycle, across seasons. Materials and Methods: In this descriptive cross-sectional study, 3,670 women who underwent their first intracytoplasmic sperm injection cycle in Mehr Medical Institute, Rasht, Iran between April 2010 and May 2014 were studied. Women were divided into four groups according to the day of oocyte retrival as: spring (n = 808), summer (n = 994), autumn (n = 1066), and winter (n = 802). Basal and stimulation charecteristics were compared among groups. Results: While sperm concentration and motility were significantly lower during summer, the total number of retrieved and metaphase II oocytes were significantly higher (p = 0.0001, p = 0.0001, p = 0.004, p = 0.02, respectively). Fertilization rate were significantly higher during autumn (p = 0.0001). Also, the number of high- quality transferred embryos were significantly higher during summer and winter (p = 0.03). A similar pattern was observed in implantation rate and pregnancy over the four seasons Conclusion: Despite the fact that intracytoplasmic sperm injection minimize the seasonal effect on pregnancy outcome, changes in pregnancy rate still occur among different seasons without particular pattern. It seems that performing assisted reproductive technology procedures in a particular season should be considered as an effective factor. Key words: Intracytoplasmic sperm injection, Seasons, Pregnancy outcome.

scholarly journals Is there any correlation between Estradiol supplementation, as luteal phase support, and clinical pregnancy in ART cycles? A cross-sectional study

2020 ◽  
Author(s):  
Maryam Eftekhar ◽  
Banafsheh Mohammadi ◽  
Esmat Mangoli ◽  
Maryam Mortazavi
Keyword(s):  
Pregnancy Rate ◽  
Embryo Transfer ◽  
Intracytoplasmic Sperm Injection ◽  
Luteal Phase ◽  
Cross Sectional Study ◽  
Clinical Pregnancy ◽  
Control Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Luteal Phase Support

Background: Endometrial receptivity is one of the important factors in assisted reproductive technology (ART) success. In the luteal phase of an ART cycle, serum estradiol (E2) and progesterone are often placed in low levels. Supporting the luteal phase with progesterone is a usual method. Objective: To evaluate the effects of E2 supplementation plus progesterone on the luteal phase support in the antagonist protocol who have undergone intracytoplasmic sperm injection-embryo transfer cycles. Materials and Methods: In this cross-sectional study, 200 patients with antagonist stimulation protocol, who had undergone intracytoplasmic sperm injection treatment, were divided into two groups based on the use of E2 supplementation. In both groups, 400 mg progesterone suppositories (Cyclogest®), twice a day/vaginally, was administered starting from the day of oocyte collection until the fetal heart activity. However, in the E2 group, in addition to progesterone, 4 mg tablet of E2 was received daily. Beta hCG was checked 14 days after the embryo transfer, and the clinical pregnancy rate was the main endpoint. Results: The patients’ characteristics were matched, and insignificant differences were observed, except for endometrial thickness. The clinical outcomes showed the rate of pregnancy was higher in the E2 group compared to the control group; nonetheless, statistically, there was no noticeable difference. Conclusion: E2 supplementation had no beneficial effect in the luteal phase support of IVF cycles. Nevertheless, more studies are required to confirm the supportive role of E2 supplementation for embryo implantation and to improve the outcomes in ART cycles. Key words: Luteal phase, Estradiol, Progesterone, ICSI, Pregnancy rate.

scholarly journals The effect of stone and patient characteristics in predicting extra-corporal shock wave lithotripsy success rate: A cross sectional study

2021 ◽  
Vol 70 ◽  
pp. 102829
Author(s):  
Mohammad Al- zubi ◽  
Ammar Al Sleibi ◽  
Basel Mazen Elayan ◽  
Subhi Zahi Al-issawi ◽  
Morad Bani-hani ◽  
...  
Keyword(s):  
Shock Wave ◽  
Success Rate ◽  
Shock Wave Lithotripsy ◽  
Patient Characteristics ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Success Rate of Endoscopic Sphenopalatine Artery Ligation for the Management of Refractory Posterior Epistaxis Patients in a Tertiary Care Hospital: A Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (232) ◽  
Author(s):  
Meenakshi Basnet ◽  
Bibek Ghimire ◽  
Akriti Shrestha ◽  
Gyan Raj Aryal
Keyword(s):  
Success Rate ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Medical Emergency ◽  
Care Hospital ◽  
Sectional Study ◽  
Artery Ligation ◽  
Cross Sectional ◽  
Sphenopalatine Artery

Introduction: Epistaxis is a common medical emergency with 5% to 15% of patients admitted for epistaxis will require surgical management as nasal packing has high failure rates. A modern endoscopic technique like Endoscopic Sphenopalatine Artery Ligation has increased in popularity for managing intractable posterior epistaxis. It has less complication and a high success rate. The study conducted to estimate the success rate of Endoscopic Sphenopalatine Artery Ligation of refractory posterior epistaxis among admitted patients in a tertiary care hospital. Methods: This is a descriptive cross-sectional study conducted from June 2019 to June 2020 at the Department of Otorhinolaryngology, Nobel Medical College and Teaching Hospital among the patient with refractory posterior epistaxis with the help of retrospective data. A convenient sampling method was used. These patients underwent endoscopic sphenopalatine artery cauterization for recurrent/intractable posterior epistaxis. Ethical clearance was taken from the Institutional Review Board. Data were analyzed in Statistical Package for the Social Sciences. Results: Out of the total patient with refractory posterior epistaxis who underwent Endoscopic Sphenopalatine Artery Ligation, the overall success rate was 39 (95.12%). Among them, 25 (60.97%) males and 16 (39.02%) females underwent endoscopic sphenopalatine artery ligation. Twenty (48.78%) of them were unilateral whilst 21 (51.21%) were bilateral disease. About 2 (4.8%) cases had re-bleeding within 48 hours which was managed conservatively. Hypertension was found to be the most common comorbid condition followed by diabetes, chronic kidney. Conclusions: From our study, we conclude that the success rate for Endoscopic Sphenopalatine Artery Ligation in a patient with refractory posterior epistaxis was high.

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