III. The Fundamental Interest in Marriage

The availability of nonradioactive methods to label nucleic acids an the resultant rapid and greater sensitivity of detection has catapulted the technique of in situ hybridization to become the method of choice to locate of specific DNA and RNA sequences on chromosomes and in whole cells in cytological preparations in many areas of biology. It is being applied to problems of fundamental interest to basic cell and molecular biologists such as the organization of the interphase nucleus in the context of putative functional domains; it is making major contributions to genome mapping efforts; and it is being applied to the analysis of clinical specimens. Although fluorescence detection of nucleic acid hybrids is routinely used, certain questions require greater resolution. For example, very closely linked sequences may not be separable using fluorescence; the precise location of sequences with respect to chromosome structures may be below the resolution of light microscopy(LM); and the relative positions of sequences on very small chromosomes may not be feasible.

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Nuclear Reactions in Deuterium Titanium

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100134260 ◽

1990 ◽

Vol 48 (2) ◽

pp. 134-135

Author(s):

D.M. Vanderwalker

Keyword(s):

Nuclear Reactions ◽

Ion Beam ◽

Exothermic Reaction ◽

Pure Titanium ◽

Fundamental Interest ◽

Transmission Electron ◽

Iodide Titanium ◽

A Cell ◽

After Hours ◽

Quantity Of Heat

There is a fundamental interest in electrochemical fusion of deuterium in palladium and titanium since its supposed discovery by Fleischmann and Pons. Their calorimetric experiments reveal that a large quantity of heat is released by Pd after hours in a cell, suggesting fusion occurs. They cannot explain fusion by force arguments, nor can it be an exothermic reaction on the formation of deuterides because a smaller quantity of heat is released. This study examines reactions of deuterium in titanium.Both iodide titanium and 99% pure titanium samples were encapsulated in vacuum tubes, annealed for 2h at 800 °C. The Ti foils were charged with deuterium in a D2SO4 D2O solution at a potential of .45V with respect to a calomel reference junction. Samples were ion beam thinned for transmission electron microscopy. The TEM was performed on the JEOL 200CX.The structure of D charged titanium is α-Ti with hexagonal and fee deuterides.

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Visible-Light Activated [2+2] Photocycloaddition Reaction Enabled Identification of Carbon-Carbon Double Bonds Position Isomerism in Structural Lipidomics

10.26434/chemrxiv.11813475 ◽

2020 ◽

Author(s):

Guifang Feng ◽

Yanhong Hao ◽

Liang Wu ◽

Suming Chen

Keyword(s):

Visible Light ◽

Uv Light ◽

Practical Importance ◽

Side Reactions ◽

Potential Health ◽

Fundamental Interest ◽

Unsaturated Lipids ◽

Health Damage ◽

Global Identification ◽

Polyunsaturated Lipids

The photocycloaddition of olefins with carbonyls is of fundamental interest and practical importance in C=C bond location in unsaturated lipids. However, the traditional UV light activated [2+2] photocycloaddition reaction suffers side reactions and potential health damage. Here, we reported the first example of visible-light activated [2+2] photocycloaddition of anthraquinone with unsaturated lipids. This reaction showed great capability for locating the C=C bonds in various kinds of monounsaturated and polyunsaturated lipids by combining with tandem mass spectrometry (MS), such as fatty acids, phospholipids and glycerides. Based on this developed reaction, a workflow with liquid chromatography tandem MS method was developed for the global identification of unsaturated lipids in human serum, and 86 of monounsaturated and complicated polyunsaturated lipids were identified with definitive positions of C=C bonds. This approach provides new insights both on the photocycloaddition reactions and the structural lipidomics.

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Short-Term Exuberance and Long-Term Stability: A Simultaneous Optimization of Stock Return Predictions for Short and Long Horizons

Mathematics ◽

10.3390/math9060620 ◽

2021 ◽

Vol 9 (6) ◽

pp. 620

Author(s):

Ioannis Kyriakou ◽

Parastoo Mousavi ◽

Jens Perch Nielsen ◽

Michael Scholz

Keyword(s):

Stock Returns ◽

Simultaneous Optimization ◽

Investment Risk ◽

Short Term ◽

Fundamental Interest ◽

Long Term Stability ◽

Risk Appetite ◽

Short And Long Term ◽

Excess Stock Returns

The fundamental interest of investors in econometric modeling for excess stock returns usually focuses either on short- or long-term predictions to individually reduce the investment risk. In this paper, we present a new and simple model that contemporaneously accounts for short- and long-term predictions. By combining the different horizons, we exploit the lower long-term variance to further reduce the short-term variance, which is susceptible to speculative exuberance. As a consequence, the long-term pension-saver avoids an over-conservative portfolio with implied potential upside reductions given their optimal risk appetite. Different combinations of short and long horizons as well as definitions of excess returns, for example, concerning the traditional short-term interest rate but also the inflation, are easily accommodated in our model.

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Solid-state nanopore systems: from materials to applications

NPG Asia Materials ◽

10.1038/s41427-021-00313-z ◽

2021 ◽

Vol 13 (1) ◽

Author(s):

Yuhui He ◽

Makusu Tsutsui ◽

Yue Zhou ◽

Xiang-Shui Miao

Keyword(s):

Solid State ◽

Recent Progress ◽

State Of The Art ◽

Ion Selectivity ◽

Dna Origami ◽

Fundamental Interest ◽

Reverse Electrodialysis ◽

Promising Application ◽

Flow Through ◽

Wall Materials

AbstractIon transport and hydrodynamic flow through nanometer-sized channels (nanopores) have been increasingly studied owing to not only the fundamental interest in the abundance of novel phenomena that has been observed but also their promising application in innovative nanodevices, including next-generation sequencers, nanopower generators, and memristive synapses. We first review various kinds of materials and the associated state-of-the-art processes developed for fabricating nanoscale pores, including the emerging structures of DNA origami and 2-dimensional nanopores. Then, the unique transport phenomena are examined wherein the surface properties of wall materials play predominant roles in inducing intriguing characteristics, such as ion selectivity and reverse electrodialysis. Finally, we highlight recent progress in the potential application of nanopores, ranging from their use in biosensors to nanopore-based artificial synapses.

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A new hierarchy of integrable system of1+2dimensions: from Newton's law to generalized Hamiltonian system. Part II

International Journal of Mathematics and Mathematical Sciences ◽

10.1155/ijmms/2006/70747 ◽

2006 ◽

Vol 2006 ◽

pp. 1-10

Author(s):

Xuncheng Huang ◽

Guizhang Tu

Keyword(s):

Integrable System ◽

Integrable Systems ◽

Hamiltonian Equation ◽

Hamiltonian Form ◽

Fundamental Interest ◽

Newton's Law ◽

Newton’S Law ◽

System Part ◽

Generalized Hamiltonian System ◽

Physical Laws

The Hamiltonian equation provides us an alternate description of the basic physical laws of motion, which is used to be described by Newton's law. The research on Hamiltonian integrable systems is one of the most important topics in the theory of solitons. This article proposes a new hierarchy of integrable systems of1+2dimensions with its Hamiltonian form by following the residue approach of Fokas and Tu. The new hierarchy of integrable system is of fundamental interest in studying the Hamiltonian systems.

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Tuning Multicolor Emission from a Single Fluorophore via Controlled Radical Polymerization-Mediated Charge Transfer

10.26434/chemrxiv.12366773 ◽

2020 ◽

Author(s):

Suiying Ye ◽

Tian tian ◽

Andrew J. Christofferson ◽

Sofia Erikson ◽

Jakub Jagielski ◽

...

Keyword(s):

Charge Transfer ◽

Radical Polymerization ◽

Molecular Design ◽

Controlled Radical Polymerization ◽

General Strategy ◽

Fundamental Interest ◽

Solid States ◽

Emission Color ◽

Theoretical Investigations ◽

Practical Implications

<p>Tuning emission color of molecular fluorophores is of fundamental interest as it directly reflects the manipulation of excited states at the quantum-mechanical level. Despite recent progress in molecular design and engineering on single fluorophores, a systematic methodology to obtain multicolor emission in aggregated or solid states, which gives rise to practical implications in different fields, remains scarce. This is due to the complex interplay between the charge-transfer (CT) and singlet excitons. In this study, we present a general strategy to tune the emission color of a single-fluorophore aggregate by controlled radical polymerization-mediated charge transfer. Using a library of well-defined styrenic donor (D) polymers grown from an acceptor (A) fluorophore by atom transfer radical polymerization (ATRP), we found that the solid-state emission color can be fine-tuned by varying three molecular parameters: (i) the monomer substituent, (ii) the end-groups of the polymer, and (iii) the polymer chain length. Experimental and theoretical investigations reveal that the color tunability originates from the structurally dependent through-space charge transfer (TSCT) process that regulates CT energy. We further demonstrate that the polymer systems can be processed into thin films enabling versatile photolithography.</p>

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Tuning Multicolor Emission from a Single Fluorophore via Controlled Radical Polymerization-Mediated Charge Transfer

10.26434/chemrxiv.12366773.v1 ◽

2020 ◽

Author(s):

Suiying Ye ◽

Tian tian ◽

Andrew J. Christofferson ◽

Sofia Erikson ◽

Jakub Jagielski ◽

...

Keyword(s):

Charge Transfer ◽

Radical Polymerization ◽

Molecular Design ◽

Controlled Radical Polymerization ◽

General Strategy ◽

Fundamental Interest ◽

Solid States ◽

Emission Color ◽

Theoretical Investigations ◽

Practical Implications

<p>Tuning emission color of molecular fluorophores is of fundamental interest as it directly reflects the manipulation of excited states at the quantum-mechanical level. Despite recent progress in molecular design and engineering on single fluorophores, a systematic methodology to obtain multicolor emission in aggregated or solid states, which gives rise to practical implications in different fields, remains scarce. This is due to the complex interplay between the charge-transfer (CT) and singlet excitons. In this study, we present a general strategy to tune the emission color of a single-fluorophore aggregate by controlled radical polymerization-mediated charge transfer. Using a library of well-defined styrenic donor (D) polymers grown from an acceptor (A) fluorophore by atom transfer radical polymerization (ATRP), we found that the solid-state emission color can be fine-tuned by varying three molecular parameters: (i) the monomer substituent, (ii) the end-groups of the polymer, and (iii) the polymer chain length. Experimental and theoretical investigations reveal that the color tunability originates from the structurally dependent through-space charge transfer (TSCT) process that regulates CT energy. We further demonstrate that the polymer systems can be processed into thin films enabling versatile photolithography.</p>

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"ZAWAED SAHIH IBN KHUZAYMAH" ON THE SIX BOOKS IN THE BOOK OF THE "IMAMATE" COLLECTING, STUDYING AND AUTHENTICATING

Researcher Journal For Islamic Sciences ◽

10.37940/rjis.2021.1.1.17 ◽

2021 ◽

Author(s):

Muhammad Al-Ani

Keyword(s):

Research Method ◽

Fundamental Interest ◽

The Third ◽

Research Plan

: I singled out (the appendices of Sahih Ibn Khuzaymah on the six books in the book of the Imamate) by graduating the hadiths of Sahih Ibn Khuzaymah first. Guided by the rules of the principles of takhrej and the sciences of hadith, the words of the imams of this art, their rulings and their investigations. Then it singled out the hadiths that were superfluous in addition to the six books, and legitimized the hadith with its chain of narrators and its text, as in Sahih Ibn Khuzaymah. I singled them out on the hadiths of the six books of the fundamentals, or some of them, based on the most correct of the sayings of the imams such as Al-Haythami, Al-Busairi, Ibn Hajar and Al-Kitani in defining the science of appendages in their books. Then I classified it according to the books and jurisprudence chapters found in the Sahih, and mentioned the book and the chapter under which the excess hadith came under, and mentioned the chapter in its entirety without abbreviation, in order to ensure the jurisprudential, hadith, linguistic and fundamental interest contained in the chapter. The research was divided into an introduction and five chapters. As for the introduction, it mentioned the virtue of the Prophetic Sunnah, the importance of the topic and the reason for choosing it, the research plan and the research method in studying the hadiths of appendices. As for the first topic, it mentioned the additional hadiths on the virtue of congregational prayer. The second topic came in the hadiths of reprimand about the imam of whom you hate to lead. As for the third topic, it contained hadiths about the resurrection of the congregation behind the imam. In the fourth topic, he mentioned the hadiths of excuses for leaving the congregational prayer. She concluded with the fifth topic the hadiths of women's prayer in congregation. The authentic hadiths in the Book of Imamate [249] amounted to two hundred and forty-nine hadiths, the excess of them [21] is twenty-one, ie 8%.

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II. Sublethal Effects And Changes In Ecosystems - Assessment of the effects of pollutants on physiology and behaviour

Proceedings of the Royal Society of London Series B Biological Sciences ◽

10.1098/rspb.1971.0032 ◽

1971 ◽

Vol 177 (1048) ◽

pp. 307-320 ◽

Cited By ~ 22

Keyword(s):

Heavy Metal ◽

Central Nervous System ◽

Heavy Metal Ions ◽

Sublethal Effects ◽

Practical Significance ◽

Mining Wastes ◽

Fundamental Interest ◽

Ecological Changes ◽

The Central Nervous System

Many pollutants, even when present in the water in concentrations well below lethal levels, may cause marked changes in the physiology and behaviour of fish. The work reported deals mainly with salmonids. The responses to insecticides are particularly interesting. Of fundamental interest is the suggestion that DDT seems to act by interfering with the normal thermal acclimation mechanism(s), probably within the central nervous system. The results are not without practical significance. Some responses, including those induced by heavy metal ions from mining wastes, may cause long-term ecological changes of consequence.

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