scholarly journals Identification of research trends concerning application of stent implantation in the treatment of pancreatic diseases by quantitative and biclustering analysis: a bibliometric analysis

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e7674 ◽  
Author(s):  
Xuan Zhu ◽  
Xing Niu ◽  
Tao Li ◽  
Chang Liu ◽  
Lijie Chen ◽  
...  
Keyword(s):  
Stent Implantation ◽  
High Frequency ◽  
Clinical Applications ◽  
Future Research ◽  
Fourth Quadrant ◽  
Medical Subject Headings ◽  
Pancreatic Diseases ◽  
Mesh Terms ◽  
Cluster Strategy ◽  
Occurrence Matrix

Objectives In recent years, with the development of biological materials, the types and clinical applications of stents have been increasing in pancreatic diseases. However, relevant problems are also constantly emerging. Our purpose was to summarize current hotspots and explore potential topics in the fields of the application of stent implantation in the treatment of pancreatic diseases for future scientific research. Methods Publications on the application of stents in pancreatic diseases were retrieved from PubMed without language limits. High-frequency Medical Subject Headings (MeSH) terms were identified through Bibliographic Item Co-Occurrence Matrix Builder (BICOMB). Biclustering analysis results were visualized utilizing the gCLUTO software. Finally, we plotted a strategic diagram. Results A total of 4,087 relevant publications were obtained from PubMed until May 15th, 2018. Eighty-three high-frequency MeSH terms were identified. Biclustering analysis revealed that these high-frequency MeSH terms were classified into eight clusters. After calculating the density and concentricity of each cluster, strategy diagram was presented. The cluster 5 “complications such as pancreatitis associated with stent implantation” was located at the fourth quadrant with high centricity and low density. Conclusions In our study, we found eight topics concerning the application of stent implantation in the treatment of pancreatic diseases. How to reduce the incidence of postoperative complications and improve the prognosis of patients with pancreatic diseases by stent implantation could become potential hotspots in the future research.

scholarly journals Evolution of knowledge on meniscal biomechanics: a 40 year perspective

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Amin Mohamadi ◽  
Kaveh Momenzadeh ◽  
Aidin Masoudi ◽  
Kempland C. Walley ◽  
Kenny Ierardi ◽  
...  
Keyword(s):  
Future Research ◽  
Fe Model ◽  
Cruciate Ligaments ◽  
Fe Modeling ◽  
Meniscal Tears ◽  
Medical Subject Headings ◽  
Model Studies ◽  
The Past ◽  
Mesh Terms ◽  
Kinematic Studies

Abstract Background Knowledge regarding the biomechanics of the meniscus has grown exponentially throughout the last four decades. Numerous studies have helped develop this knowledge, but these studies have varied widely in their approach to analyzing the meniscus. As one of the subcategories of mechanical phenomena Medical Subject Headings (MeSH) terms, mechanical stress was introduced in 1973. This study aims to provide an up-to-date chronological overview and highlights the evolutionary comprehension and understanding of meniscus biomechanics over the past forty years. Methods A literature review was conducted in April 2021 through PubMed. As a result, fifty-seven papers were chosen for this narrative review and divided into categories; Cadaveric, Finite element (FE) modeling, and Kinematic studies. Results Investigations in the 1970s and 1980s focused primarily on cadaveric biomechanics. These studies have generated the fundamental knowledge basis for the emergence of FE model studies in the 1990s. As FE model studies started to show comparable results to the gold standard cadaveric models in the 2000s, the need for understanding changes in tissue stress during various movements triggered the start of cadaveric and FE model studies on kinematics. Conclusion This study focuses on a chronological examination of studies on meniscus biomechanics in order to introduce concepts, theories, methods, and developments achieved over the past 40 years and also to identify the likely direction for future research. The biomechanics of intact meniscus and various types of meniscal tears has been broadly studied. Nevertheless, the biomechanics of meniscal tears, meniscectomy, or repairs in the knee with other concurrent problems such as torn cruciate ligaments or genu-valgum or genu-varum have not been extensively studied.

scholarly journals Scientometric Analysis of Dental Implant Research over the Past 10 Years and Future Research Trends

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Xin Huang ◽  
Jin Bai ◽  
Xu Liu ◽  
Zhaosong Meng ◽  
Yuli Shang ◽  
...  
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
High Frequency ◽  
Visual Analysis ◽  
Hot Spot ◽  
Research Field ◽  
Future Research ◽  
Scientometric Analysis ◽  
Mesh Terms ◽  
Sinus Floor

Background. We conducted a bibliometrics analysis to explore the recent trends in dental implant research which could help researchers have a clear grasp of the relevant research hotspots and prospects. Material and Methods. Altogether, 15,770 articles on dental implants, from January 1, 2010, to October 31, 2019, were selected from the Web of Science Core Collection. We used BICOMB software to extract the high-frequency MeSH terms and construct binary and coword matrices. gCLUTO software was used for biclustering and visual analysis, Ucinet 6 software for social network analysis, SCIMAT software for strategic diagram building, Citespace 5.5 software to form timeline visualization, and VOSviewer software, eventually, for bibliometrics cocitation network. Results. Altogether, 72 high-frequency keywords were extracted from the selected articles and 4 clusters and 7 subcategories were identified through biclustering analysis in the dental implant research field. The use of the strategic diagram also enabled us to find the research hotspot and development trends. Conclusions. The survival rate of dental implants and subsequent restoration have always been the core focus of research. Sinus floor elevation and guided bone regeneration are worthy of constant exploration owing to their reliability. With continuous improvement in technology, immediate loading could become a future research hot spot.

scholarly journals Mapping theme trends and knowledge structure of labor analgesia: a quantitative, co-word biclustering analysis of data in 2000-2020

2021 ◽  
Keyword(s):  
Social Network ◽  
High Frequency ◽  
Numerical Data ◽  
Knowledge Structure ◽  
Labor Analgesia ◽  
Routes Of Administration ◽  
Mesh Terms ◽  
Scientific Papers ◽  
Drug Doses ◽  
Occurrence Matrix

Background: The distribution knowledge structure and pattern of the literature on labor analgesia in PubMed were examined. Methods: Scientific papers on labor analgesia published from 1 January, 2000 to 31 June, 2020 were retrieved. The extracted MeSH items were quantitatively analyzed by the Bibliographic Item Co-Occurrence Matrix Builder (BICOMB), and the high frequency MeSH items were identified. In gCLUTO software, repeated bisection method was used to Mountain visualisation, and the visual matrix was established. By constructing high-frequency MeSH terms co-occurrence matrix, strategic diagram and social network are further completed. Results: The search strategy yielded 2870 papers, and the number of papers published annually had changed slightly during the study period. Among all extracted MeSH terms, 42 high-frequency MeSH terms were identified by consensus, and were divided into six categories by diclustering analysis. In the strategic diagram, the methods of labor analgesia, drug doses, and routes of administration were properly presented. In contrast, statistical and numerical data on obstetric analgesia were relatively underdeveloped, and management of pain during labor was undeveloped. In the social network analysis, the position status of each component was determined by the centrality values. Conclusions: The findings on labor analgesia are relatively divergent, and the six research categories outlined in this study reflect the publication trends in the field of labor analgesia to some extent. Our quantitative bibliometric research across a 20-year span depicts the overall direction of the latest topics and provides some hints for researchers when launching new projects.

scholarly journals Landscape of Infantile Hemangioma Management Trends on the 100 Top-Cited Articles Since 2010: Bibliometric Analysis

2021 ◽  
Author(s):  
Meng-Ju Li ◽  
Lin-Yen Wang ◽  
Tsair-wei Chien ◽  
Feng-Jie Lai ◽  
Kuang-Wen Liao ◽  
...  
Keyword(s):  
Management Strategies ◽  
Treatment Guideline ◽  
Infantile Hemangioma ◽  
Vascular Tumor ◽  
Mesh Term ◽  
Impact Factors ◽  
Future Research ◽  
Ulcer Formation ◽  
Medical Subject Headings ◽  
Mesh Terms

Abstract Background: An infantile hemangioma (IH) is a type of benign vascular tumor that affects babies. They usually begin during the first four weeks of life, grow until about five months of life, and then shrink in size and disappear over the next few years. Complications may include pain, bleeding, ulcer formation, heart failure, or disfigurement. Numerous articles on IH have been published in literature, sharing expanded management strategies. Nevertheless, definite treatment guideline for IH is inconclusive due to differences in heterogenous presentations, varied severity and treatment strategy among countries. This study aimed to apply the medical subject headings (MeSH terms) to predict the number of article citations using 100 top-cited IH articles (T100IHs) and dissect their characteristics including the influential authors and affiliated counties since 2010.Methods: By searching the PubMed Central® (PMC) database, the T100IHs since 2010 were downloaded. Citation analysis was performed to compare the dominant countries and authors using social network analysis (SNA) and visual representations. MeSH terms were clustered by SNA when referring their citations in articles. The prediction effect was assessed based on its correlation coefficients (CC) between impact factors(IF) of MeSH terms and the T100IHs. Results: We observed that (1) the top three productive countries and journals in T100IHs were the US (49%), China (10%), France (8%); and Pediatrics (10%), Br J Dermatol (6%), Pediatr Dermatol (4%); (2) the most cited article (PMID=25693013 with 145 citations) was authored by Christine Léauté-Labrèze from France in 2015; (3) the most cited MeSH term was pharmacology with IF equal to 42.46 in T100IHs. MeSH terms were evident in prediction power on the number of article citations (correlation coefficient = 0.46; t = 5.11; p<0.01, n = 100). Conclusion: The breakthrough was made by making the citation prediction on T100IHs. MeSH terms are evident in predicting article citations using SNA and IF calculation approaches that can be applied to future research, and is not limited to the IH topic as we did in this study.

Liraglutide for the Treatment of Obesity: Analyzing Published Reviews

2019 ◽  
Vol 25 (15) ◽  
pp. 1783-1790 ◽  
Author(s):  
Rosario Pastor ◽  
Josep A. Tur
Keyword(s):  
Weight Loss ◽  
Clinical Trials ◽  
Systematic Reviews ◽  
Randomized Clinical Trials ◽  
Statistical Tests ◽  
Overweight And Obesity ◽  
Cochrane Library ◽  
Medical Subject Headings ◽  
Mesh Terms ◽  
Treatment Of Obesity

Background: Several drugs have been currently approved for the treatment of obesity. The pharmacokinetic of liraglutide, as well as the treatment of type 2 diabetes mellitus, have been widely described. Objective: To analyze the published systematic reviews on the use of liraglutide for the treatment of obesity. Methods: Systematic reviews were found out through MEDLINE searches, through EBSCO host and the Cochrane Library based on the following terms: "liraglutide" as major term and using the following Medical Subject Headings (MesH) terms: "obesity", "overweight", "weight loss". A total of 3 systematic reviews were finally included to be analyzed. Results: From the three systematic reviews selected, only two included the randomized clinical trials, while the third study reviewed both randomized and non-randomized clinical trials. Only one review performed statistical tests of heterogeneity and a meta-analysis, combining the results of individual studies. Another review showed the results of individual studies with odds ratio and confidence interval, but a second one just showed the means and confidence intervals. In all studies, weight loss was registered in persons treated with liraglutide in a dose dependent form, reaching a plateau at 3.0 mg dose, which was reached just in men. Most usual adverse events were gastrointestinal. Conclusion: More powerful and prospective studies are needed to assess all aspects related to liraglutide in the overweight and obesity treatment.

The Role of Leukotrienes Inhibitors in the Management of Chronic Inflammatory Diseases

2020 ◽  
Vol 14 (1) ◽  
pp. 15-31
Author(s):  
Deepak Meshram ◽  
Khushbo Bhardwaj ◽  
Charulata Rathod ◽  
Gail B. Mahady ◽  
Kapil K. Soni
Keyword(s):  
Respiratory Diseases ◽  
Inflammatory Diseases ◽  
Leukotriene B4 ◽  
Published Data ◽  
Free Text ◽  
Plant Origin ◽  
Medical Subject Headings ◽  
Leukotriene Antagonists ◽  
Mesh Terms ◽  
Mediators Of Inflammation

Background: Leukotrienes are powerful mediators of inflammation and interact with specific receptors in target cell membrane to initiate an inflammatory response. Thus, Leukotrienes (LTs) are considered to be potent mediators of inflammatory diseases including allergic rhinitis, inflammatory bowel disease and asthma. Leukotriene B4 and the series of cysteinyl leukotrienes (C4, D4, and E4) are metabolites of arachidonic acid metabolism that cause inflammation. The cysteinyl LTs are known to increase vascular permeability, bronco-constriction and mucus secretion. Objectives: To review the published data for leukotriene inhibitors of plant origin and the recent patents for leukotriene inhibitors, as well as their role in the management of inflammatory diseases. Methods: Published data for leukotrienes antagonists of plant origin were searched from 1938 to 2019, without language restrictions using relevant keywords in both free text and Medical Subject Headings (MeSH terms) format. Literature and patent searches in the field of leukotriene inhibitors were carried out by using numerous scientific databases including Science Direct, PubMed, MEDLINE, Google Patents, US Patents, US Patent Applications, Abstract of Japan, German Patents, European Patents, WIPO and NAPRALERT. Finally, data from these information resources were analyzed and reported in the present study. Results: Currently, numerous anti-histaminic medicines are available including chloropheneremine, brompheniramine, cetirizine, and clementine. Furthermore, specific leukotriene antagonists from allopathic medicines are also available including zileuton, montelukast, pranlukast and zafirlukast and are considered effective and safe medicines as compared to the first generation medicines. The present study reports leukotrienes antagonistic agents of natural products and certain recent patents that could be an alternative medicine in the management of inflammation in respiratory diseases. Conclusion: The present study highlights recent updates on the pharmacology and patents on leukotriene antagonists in the management of inflammation respiratory diseases.

scholarly journals An approach to emerging optical and optoelectronic applications based on NiO micro- and nanostructures

Nanophotonics ◽  
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
María Taeño ◽  
David Maestre ◽  
Ana Cremades
Keyword(s):  
Gas Sensors ◽  
High Frequency ◽  
Future Research ◽  
Electrochromic Devices ◽  
Fuel Cell Electrodes ◽  
Magnetic Devices ◽  
Optical Microresonators ◽  
Optical Limiters ◽  
Recent Developments ◽  
Potential Applicability

Abstract Nickel oxide (NiO) is one of the very few p-type semiconducting oxides, the study of which is gaining increasing attention in recent years due to its potential applicability in many emerging fields of technological research. Actually, a growing number of scientific works focus on NiO-based electrochromic devices, high-frequency spintronics, fuel cell electrodes, supercapacitors, photocatalyst, chemical/gas sensors, or magnetic devices, among others. However, less has been done so far in the development of NiO-based optical devices, a field in which this versatile transition metal oxide still lags in performance despite its potential applicability. This review could contribute with novelty and new forefront insights on NiO micro and nanostructures with promising applicability in optical and optoelectronic devices. As some examples, NiO lighting devices, optical microresonators, waveguides, optical limiters, and neuromorphic applications are reviewed and analyzed in this work. These emerging functionalities, together with some other recent developments based on NiO micro and nanostructures, can open a new field of research based on this p-type material which still remains scarcely explored from an optical perspective, and would pave the way to future research and scientific advances.

scholarly journals Newer Volatile Anesthetic Agents in Cardiac Anesthesia: Review of Literature

2021 ◽  
Author(s):  
Alka Mandke ◽  
Manjula Sarkar ◽  
Charulata Deshpande ◽  
Arun Maheshwari ◽  
Bhupesh Kumar ◽  
...  
Keyword(s):  
Volatile Anesthetic ◽  
Cochrane Library ◽  
Cochrane Central Register ◽  
Cardiac Anesthesia ◽  
Medical Subject Headings ◽  
Holistic View ◽  
Anesthetic Agents ◽  
Cardiac Anaesthesia ◽  
Mesh Terms ◽  
Inhalational Anaesthesia

AbstractMyocardial protection with volatile anesthetic agents have been suggested by multiple studies. These studies, however, are scattered and are often limited to a particular aspect of cardiac anesthesia. Older inhalational agents like halothane is known to cause significant hepatic damage in patients undergoing long duration surgeries while isoflurane is known to have marked vasodilating properties that also affects the coronary arteries leading to coronary “steal” phenomenon. Additionally, newer agents, like sevoflurane and desflurane, have shown more prominent cardioprotective effects than older agents. We searched ScholarOne, Medline, Embase, and the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library. The medical subject headings (MeSH) terms “anaesthesia, inhalational,” “anaesthesia, intravenous, or TIVA,” and “Cardiac anaesthesia or Cardiac Surgery” were used. Additional studies were identified by review of the reference sections of all eligible studies. The aim of this review article is to bring together the evidences with newer inhalational agents and provide a holistic view of their benefits and shortcomings in cardiac anesthesia.

Hyaluronic Acid Fillers for Midface Augmentation: A Systematic Review

2021 ◽  
Author(s):  
Lily N. Trinh ◽  
Amar Gupta
Keyword(s):  
Systematic Review ◽  
Hyaluronic Acid ◽  
Subcutaneous Tissue ◽  
Age Groups ◽  
Medical Subject Headings ◽  
Mesh Terms ◽  
Full Text Review ◽  
Filler Injections ◽  
Subjective Measurements ◽  
Meta Analyses

AbstractInjectable fillers represent one of the most requested minimally invasive treatments to rejuvenate the aging face, and its popularity is steadily rising. A vast majority of filler treatments are with hyaluronic acid (HA). The aim of this systematic review is to evaluate patient outcomes, safety profile, and administration techniques of various HA fillers for malar augmentation. A systematic review of the published literature was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and included PubMed, Embase, and Science Direct databases. Medical Subject Headings (MeSH) terms used were “cheek” OR “midface” OR “malar” and “filler” OR “hyaluronic acid” OR “Juvederm” OR “Restylane” OR “Perlane” OR “Belotero.” The initial search identified 699 articles; 256 duplicates were removed. Additional 12 studies were identified from reference lists. A total of 455 were screened by title and abstract and 387 studies were eliminated based on criteria. Also, 68 articles underwent full-text review, and 18 articles were included in the final review and involved seven different HA formulations. Men and women from many age groups were highly satisfied with their results following HA treatment for midface augmentation up to 24 months. The most common adverse events included bruising, swelling, and tenderness, and typically lasted no more than 2 weeks. Upper cheek filler injections near the zygoma should be placed in the submuscular plane while lower cheek injections should be placed in the subcutaneous tissue. HA is an attractive choice for midface augmentation due to its high patient satisfaction, long-lasting effects, and low side-effect profile. Due to the variability in technique, level of expertise, and subjective measurements across studies, one optimal regimen could not be concluded. However, midface augmentation treatment should be personalized to each patient. Additional clinical trials are required to more conclusively determine the most appropriate approach for this procedure.

scholarly journals Immune modulators in disease: integrating knowledge from the biomedical literature and gene expression

2015 ◽  
Vol 23 (3) ◽  
pp. 617-626 ◽  
Author(s):  
Nophar Geifman ◽  
Sanchita Bhattacharya ◽  
Atul J Butte
Keyword(s):  
Gene Expression ◽  
Large Scale ◽  
Biomedical Literature ◽  
Cytokine Gene Expression ◽  
Future Research ◽  
Cytokine Gene ◽  
Medical Subject Headings ◽  
Expression Arrays ◽  
Gene Expression Arrays ◽  
Subject Headings

Abstract Objective Cytokines play a central role in both health and disease, modulating immune responses and acting as diagnostic markers and therapeutic targets. This work takes a systems-level approach for integration and examination of immune patterns, such as cytokine gene expression with information from biomedical literature, and applies it in the context of disease, with the objective of identifying potentially useful relationships and areas for future research. Results We present herein the integration and analysis of immune-related knowledge, namely, information derived from biomedical literature and gene expression arrays. Cytokine-disease associations were captured from over 2.4 million PubMed records, in the form of Medical Subject Headings descriptor co-occurrences, as well as from gene expression arrays. Clustering of cytokine-disease co-occurrences from biomedical literature is shown to reflect current medical knowledge as well as potentially novel relationships between diseases. A correlation analysis of cytokine gene expression in a variety of diseases revealed compelling relationships. Finally, a novel analysis comparing cytokine gene expression in different diseases to parallel associations captured from the biomedical literature was used to examine which associations are interesting for further investigation. Discussion We demonstrate the usefulness of capturing Medical Subject Headings descriptor co-occurrences from biomedical publications in the generation of valid and potentially useful hypotheses. Furthermore, integrating and comparing descriptor co-occurrences with gene expression data was shown to be useful in detecting new, potentially fruitful, and unaddressed areas of research. Conclusion Using integrated large-scale data captured from the scientific literature and experimental data, a better understanding of the immune mechanisms underlying disease can be achieved and applied to research.

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