scholarly journals Solid Pseudopapillary Tumor of the Pancreas in a 25-Year-Old Female: A Rare Entity of Pancreatic Tumors

Cureus ◽  
2021 ◽  
Author(s):  
Dimitrios Massaras ◽  
Zoi Masourou ◽  
Maria Papazian ◽  
Grigorios Psarras ◽  
Andreas Polydorou
Keyword(s):  
Pancreatic Tumors ◽  
Solid Pseudopapillary Tumor ◽  
Rare Entity

scholarly journals Primary Pancreatic Lymphoma: a rare entity in pancreatic mass

2017 ◽  
Vol 1 (1) ◽  
pp. 58-64 ◽  
Author(s):  
Noor Dev Kandel ◽  
Nirmal Lamichhane
Keyword(s):  
Differential Diagnosis ◽  
Histopathological Examination ◽  
Radical Resection ◽  
Accurate Diagnosis ◽  
Pancreatic Tumors ◽  
Definitive Treatment ◽  
Rare Tumor ◽  
Rare Entity ◽  
Pancreatic Lymphoma ◽  
Primary Pancreatic Lymphoma

Primary pancreatic lymphoma is an extremely rare tumor of pancreas which clinico-radiologically mimics with pancreatic adenocarcinoma. The disease is diagnosed often after radical resection of pancreas. We report a case of 63 years old Chinese gentle man with diagnosis of Primary pancreatic lymphoma who was diagnose after surgical resection. Primary pancreatic lymphoma should also be considered as differential diagnosis in pancreatic tumors. There can be some radiological clues but accurate diagnosis depends on histopathological examination. Definitive treatment still remains controversial.

scholarly journals Pancreatic solid serous cystadenoma: a rare entity that can lead to a futile surgery

2019 ◽  
Vol 2019 (12) ◽  
Author(s):  
Vincent Demesmaker ◽  
Faouzi Abou-Messaoud ◽  
Muriel Parent ◽  
Bernard Vanhoute ◽  
Fadi Maassarani ◽  
...  
Keyword(s):  
Palliative Chemotherapy ◽  
Serous Cystadenoma ◽  
Definitive Diagnosis ◽  
Emission Tomography ◽  
Pancreatic Tumors ◽  
Rare Entity ◽  
Resonance Imaging ◽  
Positron Emission ◽  
Final Histological Diagnosis

Abstract Although many types of pancreatic tumors exist, pancreatic solid serous cystadenoma stand as the most rare. Despite advances in medical imaging, definitive diagnosis remains complex. Here, we report a case of a 63-year-old man with a suspicious lesion of the pancreas discovered during a positron emission tomography–computed tomography. Despite an echo-endoscopy being performed, no biopsies were contributive. The magnetic resonance imaging did highlight another lesion in the liver. Due to the suspicion of a neuroendocrine tumor of the pancreas with liver metastases, a cephalic duodenopancreatectomy with partial hepatectomy was performed. During the procedure, another hepatic lesion was resected. The final histological diagnosis was a serous solid adenoma of the pancreas associated with a cholangiocarcinoma. During the follow-up, the patient presented a massive metastatic hepatic relapse even after the administration of a palliative chemotherapy.

scholarly journals Pregnancy following Radical Resection of Solid Pseudopapillary Tumor of the Pancreas

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
James M. O’Brien ◽  
Debra Gussman ◽  
Ellen Hagopian ◽  
Theodore Matulewicz
Keyword(s):  
Residual Disease ◽  
Clinical History ◽  
Radical Resection ◽  
Term Infant ◽  
Pancreatic Tumors ◽  
Solid Pseudopapillary Tumor ◽  
Maternal Fetal Medicine ◽  
Healthy Term Infant ◽  
History Of ◽  
High Risk Clinic

Solid pseudopapillary tumor of the pancreas is a rare tumor seen in predominately young women and carries a low malignant potential. We discuss a patient, who presented to our high risk clinic, with a clinical history of solid pseudopapillary tumor of the pancreas, predating her pregnancy. The patient had undergone previous surgery and imaging which had excluded recurrence of disease; however, increased attention was paid to the patient during her pregnancy secondary to elevated hormonal levels of progesterone, which any residual disease would have a heightened sensitivity to. In cases of pregnant patients with a history of pancreatic tumors, a multidisciplinary approach with maternal fetal medicine, medicine, and general surgery is appropriate and can result in a healthy mother and healthy term infant.

scholarly journals Metastatic pancreatic ductal adenocarcinoma in a teenage girl: A rare disease

2020 ◽  
Vol 60 (6) ◽  
pp. 341-4
Author(s):  
Sutaryo Sutaryo ◽  
Scolastika Dita Kristian
Keyword(s):  
Pancreatic Ductal Adenocarcinoma ◽  
Acinar Cell Carcinoma ◽  
Abdominal Discomfort ◽  
Ductal Adenocarcinoma ◽  
Pancreatic Tumors ◽  
Solid Pseudopapillary Tumor ◽  
Teenage Girl ◽  
Pancreatic Endocrine Neoplasm ◽  
Pancreatic Cells ◽  
Tumor Types

Pancreatic ductal adenocarcinoma (PDAC) is highly uncommon in patients < 20 years of age, at less than 0.1% of population.1 Pancreatic tumors in children and adolescents can develop from endocrine or exocrine cells. The tumor types include solid pseudopapillary tumor, ductal adenocarcinoma, pancreatoblastoma, acinar cell carcinoma, and pancreatic endocrine neoplasm (malignant and benign).2 Other types of tumors may be attached to it or secondarily engage the gland or emerge from other kinds of non-pancreatic cells inside the pancreas. The prevalent type of classic PDAC in adults is highly uncommon in children.  We report here on a fifteen-year old girl with metastatic pancreatic ductal adenocarcinoma (mPDAC), who presented with abdominal discomfort and jaundice.

scholarly journals Late Onset of Pancreatic Metastases from Renal Cell Carcinoma. A Case Report

PRILOZI ◽  
2020 ◽  
Vol 41 (2) ◽  
pp. 57-62
Author(s):  
Vesna Janevska ◽  
Aleksandar Shumkovski ◽  
Dafina Nikolova ◽  
Learta Asani ◽  
Stefan Pandilov ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Rare Case ◽  
Late Onset ◽  
Immunohistochemical Analysis ◽  
Definitive Diagnosis ◽  
Pancreatic Tumors ◽  
Rare Entity ◽  
Pancreatic Metastases

AbstractMetastasis of renal cell carcinoma (RCC) to the pancreas is a rare entity accounting only 0.25–3% of all pancreatic tumors. We present a rare case of isolated three focal pancreatic metastases from RCC, occurring 15 years after the left nephrectomy. The majority of the pancreatic metastases are asymptomatic, as it was in case of our patient excluding the weight loss for the last three months. We demonstrate the importance of the medical history, radiological examinations, histological and immunohistochemical analysis in making a definitive diagnosis.

Solid-pseudopapillary tumor of the pancreas and pancreatoblastoma in children: Experience over 18 years at a Pediatric Oncology Center

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 9062-9062
Author(s):  
M. Rizzatti ◽  
E. Gatti ◽  
S. R. Brandalise ◽  
A. G. Oliveira Filho ◽  
I. A. Cardinalli ◽  
...  
Keyword(s):  
Retrospective Analysis ◽  
Pediatric Population ◽  
Disease Free Survival ◽  
Pancreatic Injury ◽  
Pancreatic Tumors ◽  
Cancer Center ◽  
Solid Pseudopapillary Tumor ◽  
Free Survival ◽  
Oncology Center

9062 Background: Malignant pancreatic tumor is a rare disease in the pediatric population. Guidelines for treatment, including management in advanced disease are controversial until this moment (REBHANDL, 2001). Regarding to the pathology findings, pancreatoblastoma and solid-pseudopapillary tumor of the pancreas (Frantz’s tumor) are the more frequent pancreatic tumors in childhood. The aim of this study was a retrospective analysis of all malignant pancreatic tumors diagnosed at Boldrini’s Children Cancer Center during a period of 18 years. Methods: A retrospective analysis of eight cases of malignant pancreatic tumors, admitted at the Boldrini’s Children Cancer Center, from January 1987 to April 2005. All the data concerning age, sex, clinical presentation, stage, treatment and follow-up were collected. Results: The patient’s population refers to 8 children. There were 4 boys and 4 girls. Age ranged from 1 month to 15 years old (median age of 14 years). Main symptom was the increase of abdominal volume. None of them had metastatic disease at diagnosis. Regarding to pathology, 4 patients had pancreatoblastoma and 4 Frantz’s tumor. One patient (who had pancreatoblastoma) received chemotherapy before surgery, with a partial response, and then had a complete tumor ressection. All others (7 patients) had complete surgery as first treatment. Only one patient with Frantz’s tumor had pancreatic injury during tumor ressection and is now receiving enzimatic reposition. All the patients are alive, free of disease, from 6 months to 11 years (median follow-up of 2 years). Table I . Conclusions: Total pancreatectomy is the most important treatment in pancreatoblastoma and Frantz’s tumor. Neoadjuvant chemotherapy may be an important tool in unresectable tumors, increasing the disease-free survival. [Table: see text] No significant financial relationships to disclose.

scholarly journals Solid pseudopapillary tumor of the pancreas: clinical-pathological features and management of 13 cases

2017 ◽  
Vol 90 (2) ◽  
pp. 171-178 ◽  
Author(s):  
Ovidiu Vasile Bochis ◽  
Madalina Bota ◽  
Emilia Mihut ◽  
Rares Buiga ◽  
Dan Samoila Hazbei ◽  
...  
Keyword(s):  
Pathological Condition ◽  
Demographic Data ◽  
Surgical Excision ◽  
The Body ◽  
Pancreatic Tumors ◽  
Solid Pseudopapillary Tumor ◽  
Young Females ◽  
Complete Surgical Excision ◽  
The Mean

Background and aim. Solid pseudopapillary tumor (SPT) of the pancreas is a rare pathological condition, representing less than 3% of all exocrine pancreatic tumors. SPT usually occurs in young females, without notable symptoms, with a low malignant potential and excellent prognosis.Method. We conducted a retrospective study during the period January 2005 - January 2015. SPT patients admitted in our institution were reviewed by describing demographic data, clinico-pathologic and radiological features, therapeutic management and prognosis records.Results. Thirteen patients with SPT were identified (10 females), with a median age of 30 years. The main clinical presentation was abdominal pain (92.3%). The tumor was mostly located in the body or tail of the pancreas (77%), and the mean size was 8.2 cm. Regarding the surgical approach there were 5 distal pancreatectomies with splenectomy, 3 body and tail pancreatectomies, 2 body and tail pancreatectomies with splenectomy, 2 pancreato-duodenectomy, 1 partial enucleation and of all only 2 partial resections. Postoperative hematoxylin- eosin staining and immunohistochemistry confirmed the diagnosis in all cases. None of the patients had lymph nodes metastases. Only one local invasion. There was one case of death due to postoperative complications. Four cases followed adjuvant systemic chemotherapy. The mean follow-up was 18 months, without evidence of recurrence during this period.Conclusion. SPT should always be considered in the differential diagnosis in young women with a pancreatic tumor. Complete surgical excision is the treatment of choice, and is usually curative. The decision to administer systemic therapy must be individualized. Malignant behavior and late recurrences mandates long-term follow-up for patients with SPT.

Clinicopathologic Review of 31 Cases of Solid Pseudopapillary Pancreatic Tumors: Can We Use the Scoring System of Microscopic Features for Suggesting Clinically Malignant Potential?

2016 ◽  
Vol 82 (4) ◽  
pp. 308-313 ◽  
Author(s):  
Jang-hee Kim ◽  
Jae-myeong Lee
Keyword(s):  
Soft Tissue ◽  
Perineural Invasion ◽  
Pancreatic Neoplasm ◽  
Malignant Potential ◽  
Pancreatic Tumors ◽  
Solid Pseudopapillary Tumor ◽  
Nuclear Pleomorphism ◽  
Pathologic Features ◽  
Microscopic Features ◽  
Potentially Malignant

A solid pseudopapillary tumor (SPT) is a pancreatic neoplasm of low malignant potential. The potentially malignant pathologic features of SPTs were regarded as angioinvasion, perineural invasion, deep invasion of the surrounding acinar tissue, and nuclear pleomorphism. We retrospectively reviewed 31 cases of SPTs (25 female and 6 male patients, with an average age of 35 ± 14 years). The mean follow-up period was 132.0 ± 55.9 months. To evaluate the clinical impact of above pathological parameters, we analyzed their correlation with actually observed clinical malignancy. In three cases, the SPTs were clearly clinically malignant: one patient had recurrences three times, one showed lymph node metastases, and one deep soft tissue invasion around the gastroduodenal artery. Tumor infiltration to the peripancreatic soft tissue was observed in 17 cases (54.8%). The pathologic features considered suggestive of malignant potential were angioinvasion (25.8%), perineural invasion (6.5%), presence of mitosis in 10 high-power fields (16.1%), and moderate nuclear pleomorphism (19.4%). The presence of at least three of these features was not correlated with clinically confirmed malignant behavior ( P = 0.570). Microscopic pathologic features of SPTs cannot be reliably associated with aggressive clinical behavior. Moreover, the absence of these microscopic features cannot exclude clinical malignancy.

scholarly journals Solid pseudopapillary tumor of the pancreas: a rare entity in children

2020 ◽  
Vol 35 ◽  
Author(s):  
Ghita Berrada ◽  
Soukaina Belaaroussi ◽  
Kamilia Chbani ◽  
Siham Salam ◽  
Dalal Laoudiyi ◽  
...  
Keyword(s):  
Solid Pseudopapillary Tumor ◽  
Rare Entity

scholarly journals Total Dorsal Pancreatectomy, an Alternative to Total Pancreatectomy: Report of a New Case and Literature Review

2018 ◽  
Vol 36 (5) ◽  
pp. 363-368 ◽  
Author(s):  
Simone Conci ◽  
Andrea Ruzzenente ◽  
Francesca Bertuzzo ◽  
Tommaso Campagnaro ◽  
Alfredo Guglielmi ◽  
...  
Keyword(s):  
Literature Review ◽  
Total Pancreatectomy ◽  
English Literature ◽  
Good Condition ◽  
Case Series ◽  
Postoperative Mortality ◽  
Pancreatic Tumors ◽  
Solid Pseudopapillary Tumor ◽  
Low Grade ◽  
Dorsal Pancreas

Background: Total dorsal pancreatectomy (TDP) is a conservative pancreatic resection that should be considered in cases of benign or low malignant tumors confined to the dorsal pancreas to preserve the viability of both digestive and biliary tracts, and to avoid the endocrine and metabolic consequences of total pancreatectomy. We report a new case of TDP and provide a literature review of this procedure. Methods: The case reported was a 35-year-old female patient with a solid pseudopapillary tumor. We resected the dorsal segment of the pancreas while preserving the common bile duct, gastroduodenal artery, and pancreaticoduodenal arcades, and the spleen and splenic vessels. The MEDLINE® and Embase® databases were searched for English language studies, case series, or case reports published through August 31, 2017. Results: The postoperative course was uneventful and patient was discharged on postoperative day 11. The patient was alive and in good condition at the 10-year follow-up. To date in English literature, there are only 3 reported cases of TDP, and all cases were patients with intraductal papillary mucinous neoplasia and pancreas divisum. There was no postoperative mortality, and 2 grade B pancreatic fistulas healed 1 month postoperatively. Conclusions: TDP is a feasible and safe operation for benign or low grade malignant pancreatic tumors involving the dorsal pancreas, as an alternative to total pancreatectomy.

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