scholarly journals Serum Neopterin Is Not Influenced by Age and Blood Group of Transfusion-Transmitted Infection Negative Blood Donors

Cureus ◽  
2020 ◽  
Author(s):  
Ahsan Ashfaq ◽  
Ayesha Ejaz ◽  
Fareena Khalil Ahmed ◽  
Noor Un Nisa ◽  
Suresh Langhani ◽  
...  
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Transmitted Infection ◽  
Serum Neopterin ◽  
Transfusion Transmitted Infection

scholarly journals Analysis of the profile of blood donors in a blood bank of a private medical college of Kolkata

2017 ◽  
Vol 4 (10) ◽  
pp. 3899 ◽  
Author(s):  
Debdutta Haldar ◽  
Kunal Kanti Majumdar ◽  
Shilpa Karir ◽  
Arun Kumar Chakraborty ◽  
Ankita Dey ◽  
...  
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Cross Sectional Study ◽  
Blood Bank ◽  
The Body ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Male Predominance ◽  
Medical College ◽  
Transfusion Transmitted Infection

Background: Blood is the only oxygen transporter in the body and is crucial in saving lives. Research has failed to find a true substitute for blood and blood components and depends on human donors. There are several infectious and non-infectious risks associated with transfusion. An unsafe transfusion is very costly from both human and economic points of view. In that perspective the present study is aimed to assess the profile of blood donors. The objectives of the study were to assess the profile of blood donors as per records of Blood Bank of a private medical college of Kolkata and to find out the prevalence and trends of transfusion transmitted infections among those donors.Methods: A record based cross sectional study was conducted for the period May 2013 to April 2016 at Blood Bank of a private medical college and information regarding 5383 blood donor’s profile were collected and analysed. Results: The total donors were found to be 5383 out of which (87.72%) were voluntary donors and (12.28%) replacement donors. The donors had a male predominance (79.84%). The most available blood group was B+ (49.42%) and the least available blood group was A- (0.38%). The commonest transfusion transmitted infection was Hepatitis B (1.11%) followed by Hepatitis C (0.28%) and HIV (0.21%). The transfusion transmitted infections (TTI) shows a decreasing trend over the 3 years. Conclusions: The voluntary donors have increased over the 3 years but there is always a male predominance. The pattern of TTIs in the blood bank depicts the national trend too. 

scholarly journals Spectrum of Transfusion Transmitted Infections Among Apparently Healthy Blood Donors in Blood Bank RIMS Ranchi From 2008 to 2014

2016 ◽  
Vol 1 (2) ◽  
Author(s):  
Sushma Kumari ◽  
Ritesh Kumar ◽  
Ramesh Kumar Srivastava
Keyword(s):  
Blood Donors ◽  
Immunochromatographic Test ◽  
Rapid Plasma Reagin ◽  
Transmitted Infection ◽  
Blood Samples ◽  
Transfusion Transmitted Infection ◽  
Malaria Antigen ◽  
One Step ◽  
Test Result ◽  
Apparently Healthy

Context: Apparently healthy blood donors might carry out transfusion transmitted infections which might be fatal for the donor himself as well as the recipient later on.Aim: To assess the seroprevalence of transfusion-transmitted infections (TTI) among apparently healthy blood donors in Ranchi, India.Methods and Materials: All blood samples were screened for HIV-I and II, HBsAg, HCV (by using third generation enzyme-linked immunoadsorbent assay technique), Syphilis (by Rapid Plasma Reagin Kit), and Malaria antigen both for plasmodium  falciparum and plasmodium vivax (by One step, rapid, immunochromatographic test).Result: On screening of 106,306 blood units for TTIs, 1,462 (1.37 %) donors were found positive for one of the TTIs. Highest prevalence was for HBV (970 donors - 0.91%) ranging from 0.73% to 1.19%. This was followed by Malaria (272 donors - 0.25%) ranging from 0.08% to 0.48%, HCV (127 donors - 0.11%) ranging from 0.04% to 0.25%, HIV (72 donors - 0.06%) ranging from 0.03% to 0.10%, and syphilis (21 donors 0.01%) ranging from 0.00% to 0.09%.Conclusions: Apparently healthy blood donors are not omitted from the danger of transfusion-transmitted infection. 

Identification of risk factors in blood donors found to have HIV infection

2000 ◽  
Vol 11 (11) ◽  
pp. 728-730 ◽  
Author(s):  
C M Bates ◽  
P B Carey ◽  
V J Martlew ◽  
A J N Shepherd
Keyword(s):  
Risk Factors ◽  
Blood Donors ◽  
Transmitted Infection ◽  
Infected Blood ◽  
Hiv Rna ◽  
North Wales ◽  
Transfusion Transmitted Infection ◽  
Immunodeficiency Virus ◽  
Donated Blood ◽  
Made In

To ascertain whether current screening procedures for human immunodeficiency virus (HIV) infected blood can be improved, a study of blood donors found by Mersey and North Wales Blood Centre to be HIV positive was made. In total 22 donors were identified, of which 16 were referred to the Department of Genito-Urinary Medicine (GUM) in Liverpool. Most (9/16) should have been excluded from donating because of recognized risk factors. However, in 7 cases no such identifiable factors were found. Although the risk of transfusion transmitted infection is small, there is an argument for testing donated blood for HIV RNA by nucleic acid technology.

scholarly journals The Prevalence of Transfusion-transmitted Infections among Blood Donors in Hospital Universiti Sains Malaysia

2020 ◽  
Vol 35 (6) ◽  
pp. e189-e189
Author(s):  
Marini Ramli ◽  
Zefarina Zulkafli ◽  
Geoffrey Keith Chambers ◽  
Raja Sabrina Amani Raja Zilan ◽  
Hisham Atan Edinur
Keyword(s):  
Blood Donors ◽  
Screening Method ◽  
Serological Testing ◽  
Donor Pool ◽  
Transmitted Infection ◽  
Infection Transmission ◽  
Transfusion Transmitted Infection ◽  
B Virus ◽  
Immunodeficiency Virus ◽  
Donated Blood

Objectives: Blood bank centers routinely screen for hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) to ensure the safety of blood supply and thus prevent the dissemination of these viruses via blood transfusion. We sought to evaluate the detection of transfusion-transmitted infection (TTI) markers using standard serological methods and nucleic acid testing (NAT) among blood donors in Hospital Universiti Sains Malaysia. Methods: Donated blood units were assessed for the presence or absence of HBV, HCV, and HIV using two screening method: serology and NAT. Reactive blood samples were then subjected to serological confirmatory and NAT discriminatory assays. Results: A total of 9669 donors were recruited from September 2017 to June 2018. Among these, 36 donors were reactive either for HBV, HCV, or HIV by serological testing and eight by NAT screening. However, only 10 (three for HBV and seven for HCV) donors tested positive using serological testing and five (two for HBV and three for HCV) by NAT discriminatory assays. Note that all five NAT positive donors detected in the NAT discriminatory assays were confirmed to be serologically reactive. Therefore, the prevalence of HBV, HCV, and HIV was 0.03%, 0.1%, and 0.0%, respectively, in our donor pool. Conclusions: Both serological and NAT screening and confirmatory assays should be used routinely to reduce the risk of infection transmission via the transfusion of blood and blood components.

scholarly journals Prevalence of Transfusion Transmitted Infection among Blood Donors at Medical University in Bangladesh

2017 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
Ferdous Ara ◽  
ABM Mashiul Alam ◽  
Manjuma Rahman ◽  
Asifa Jahan ◽  
Abdullah Yusuf ◽  
...  
Keyword(s):  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Venereal Disease ◽  
Transmitted Infection ◽  
Major Health Problem ◽  
Transfusion Transmitted Infection ◽  
Immunodeficiency Virus ◽  
The Status ◽  
Donated Blood ◽  
Medical University

Background: Blood transfusion is associated with a number of complications. Transfusion transmitted infections (TTI) are one of the major health problem in Bangladesh.Objective: The objective of the present study was to assess the status of transfusion transmitted infections among the apparently healthy donors.Methodology: This study we carried out among 12,294 blood donors from September 2009 to March 2010 at Department of Transfusion Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. All the samples were screened for hepatitis B surface antigen (HBsAg), hepatitis C virus (HCV), human immunodeficiency virus (HIV) 1 and 2, venereal disease research laboratory test (VDRL) and malaria to see the prevalence of TTI.Results: Prevalence of HBV, HCV, HIV, and syphilis were 0.009, 0.0004, 0.0001 and 0.0001% respectively. No blood donor tested showed positivity for malarial parasite.Conclusion: Mandatory screening of donated blood and use of sensitive screening test should be done to reduce TTI in Bangladesh.J Shaheed Suhrawardy Med Coll, June 2014, Vol.6(1); 11-13

scholarly journals Blood Donors Recruitment and Incentives in Bangladesh

1970 ◽  
Vol 20 (2) ◽  
pp. 129-135
Author(s):  
M Mahbub-ul-Alam ◽  
Mamun Ur Rashid ◽  
ARM Saifuddin Ekram
Keyword(s):  
Whole Blood ◽  
Blood Donors ◽  
Response Rate ◽  
Negative Impact ◽  
Or Education ◽  
Transmitted Infection ◽  
Incentive Programs ◽  
Transfusion Transmitted Infection ◽  
First Time ◽  
Blood Screening

The potential effectiveness of various donation incentive programs may vary by demographics and first time or repeat status. Attitudes towards future incentives were obtained from 2,897 whole blood donors among 5,357 allogenic donors who return a questionnaire (54.08% response rate). Majority were first time donors 67.59% (1,958) with 32.41% (939) repeated donor. Majority of the respondents were male 68.52% (1,985), female 31.48% (912). Responses to incentives were compared between first time and repeat whole blood donors. Incentives most likely to encourage donation return among all 2,897 whole blood respondents were blood screening test (B.S.T), against transfusion transmitted infection (T.T.I) 71.65%, blood credits- 61.55%, cash to charity- 43.35% and gift- 27.6%. The incentives that would be least likely to encourage return were a token or award of appreciation- 15.85%. Few donors would be discouraged to return if offered B.S.T against T.T.I (0.25%), other miscellaneous incentives (1.31%), a gift (2.15%), a token of appreciation (1.95%). Compensatory incentives could potentially have a more negative impact because 7 to 9 percent of donors reported they would be discouraged for donating if they received cash or lottery or raffle ticket. Young (18-25 years old) donors were encouraged by B.S.T against T.T.I (58.4%) and older (51 years old) donors (58.4%); more than 2 hours off work (46.2% and 13.7%); community service and / or education credits ( 44.2% and 10.7%); or compensatory incentives (56.9% and 15.8% for cash to charity 57.8% and 26.7%); gifts (39.6% and 11.4%) or a token of appreciation (27.4% and 10.0%) respectively. Blood screening and blood credits would be well received at all donation sites. Gift, compensatory incentives and token of appreciation appeal more to younger donors. These data may allow blood centers to optimize recruitment by tailoring limited incentive recourses more effectively. doi: 10.3329/taj.v20i2.3074 TAJ 2007; 20(2): 129-135

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