scholarly journals Syncephalastrum racemosum as aRare Agent of Rhino-orbital Mucormycosis:A Case Report and Review

2021 ◽  
Author(s):  
Neelam Gulati ◽  
Poonam Gupta ◽  
Charu Nayyar ◽  
BL Sherwal ◽  
Sunil Kumar
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Case Report ◽  
Paranasal Sinuses ◽  
Human Disease ◽  
Rare Case ◽  
Syncephalastrum Racemosum ◽  
The Third ◽  
Uncontrolled Diabetes ◽  
The Common

Fungal infection of the paranasal sinuses is an increasingly recognised entity both in immunocompetent and immunocompromised individuals. Aspergillus species are the most common aetiologic agents of this disease. Zygomycete agents are the common culprits in the immunocompromised group. The most common agent causing human disease is Rhizopus species followed by Rhizomucorspp. The important risk factors are uncontrolled diabetes mellitus and immunsupression. Here, a rare case of pansinusitis with Syncephalastrum racemosum was reported in a 13-year-old male child with aplastic anaemia. Syncephalastrum racemosum has been debated for its role in human diseases and very few reports are documented. To the best of our knowledge this was the third report of rhino-orbital infection caused by this fungus. Syncephalastrum racemosum should be considered as one of the aetiologic agents of rhino-orbital infections especially in the immunocompromised group.

scholarly journals Bilateral Total Aplasia of Paranasal Sinuses: A Rare Case Report

2015 ◽  
Vol 8 (3) ◽  
pp. 124-126
Author(s):  
Ankita Joshi ◽  
Chinmay Sundarray ◽  
Krishna Arpita Sahoo
Keyword(s):  
Case Report ◽  
Paranasal Sinus ◽  
Paranasal Sinuses ◽  
Rare Case ◽  
The Other ◽  
High Rate ◽  
Unknown Etiology ◽  
Structural Variations ◽  
The Third ◽  
Rare Case Report

ABSTRACT Paranasal sinus anatomical anomalies with unknown etiology are common. Paranasal sinus-related diseases are associated with so high rate of morbidities, it becomes essential to identify the structure and pathophysiology of the paranasal sinuses. Computed tomography (CT) is a valuable tool in displaying its anatomy, any anatomic variations and diseases. As paranasal sinus development is a complex and long-lasting process, there are great structural variations between individuals. Maxillary and/or frontal sinus aplasia or hypoplasia are more common than the other types. Several degrees and combinations of aplasias and hypoplasias have been reported; however, there is only two case of total paranasal sinus aplasia in the literature. Here, we present the third case of total paranasal sinus aplasia, and the first ever case reported from India. How to cite this article Joshi A, Sundarray C, Sahoo KA. Bilateral Total Aplasia of Paranasal Sinuses: A Rare Case Report. Clin Rhinol An Int J 2015;8(3):124-126.

ISOLATION OF RHIZOPUS HOMOTHALLICUS FROM A PATIENT OF RHINO-ORBITAL CEREBRAL MUCORMYCOSIS : A RARE CASE REPORT.

2021 ◽  
pp. 17-18
Author(s):  
Kanwar Bhanu ◽  
Sood Anuradha ◽  
Gupta Veetheeanveshna ◽  
Rana Aditya ◽  
Thakur Daaman ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Case Report ◽  
Rare Case ◽  
Fungal Culture ◽  
Uncontrolled Diabetes ◽  
Rare Case Report ◽  
Rhizopus Homothallicus

We report a rare case of Rhino-orbital cerebral mucormycosis ( invasive mucormycosis) caused by Rhizopus homothallicus in patient of uncontrolled diabetes mellitus. The organism was isolated from nasal scrapping and tissue obtained after surgery and was identied after fungal culture.

scholarly journals When Uncontrolled Diabetes Mellitus and Severe COVID-19 Converge: The Perfect Storm for Mucormycosis

2021 ◽  
Vol 7 (4) ◽  
pp. 298
Author(s):  
Teny M. John ◽  
Ceena N. Jacob ◽  
Dimitrios P. Kontoyiannis
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Clinical Features ◽  
The Other ◽  
Diabetic Patients ◽  
Epidemiological Factors ◽  
Uncontrolled Diabetes ◽  
Diagnostic Certainty ◽  
Patients With Diabetes ◽  
Perfect Storm

Mucormycosis (MCR) has been increasingly described in patients with coronavirus disease 2019 (COVID-19) but the epidemiological factors, presentation, diagnostic certainty, and outcome of such patients are not well described. We review the published COVID-19-associated mucormycosis (CAMCR) cases (total 41) to identify risk factors, clinical features, and outcomes. CAMCR was typically seen in patients with diabetes mellitus (DM) (94%) especially the ones with poorly controlled DM (67%) and severe or critical COVID-19 (95%). Its presentation was typical of MCR seen in diabetic patients (mostly rhino-orbital and rhino-orbital-cerebral presentation). In sharp contrast to reported COVID-associated aspergillosis (CAPA) cases, nearly all CAMCR infections were proven (93%). Treating physicians should have a high suspicion for CAMCR in patients with uncontrolled diabetes mellitus and severe COVID-19 presenting with rhino-orbital or rhino-cerebral syndromes. CAMR is the convergence of two storms, one of DM and the other of COVID-19.

Problems Of Metabolic Syndrome

2021 ◽  
Vol 03 (06) ◽  
pp. 52-55
Author(s):  
Maksuda Ahmedjanovna Karimova ◽  
◽  
Dilnoza Kakhramanovna Kurbanbaeva ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Metabolic Syndrome ◽  
Lifestyle Modification ◽  
Syndrome X ◽  
Steady Increase ◽  
The Third ◽  
Calorie Content ◽  
Single Term ◽  
Life Threatening

At the beginning of the third millennium, for mankind, which overcame the epidemic of life-threatening infections during its centuries-old history, the problem of cardiovascular diseases (CVD) came to the fore in relevance among all causes of morbidity and mortality. A significant role in this was played by lifestyle modification associated with limiting physical activity, increasing the calorie content of food, and a steady increase in emotional stress. All of this potentiates the main risk factors for CVD, which are a “negative asset of progress,” namely increased blood pressure (BP), dyslipidemia, diabetes mellitus (DM) and obesity. Since 1988, after G. Reaven's Banting lecture, it is customary to designate the interconnected combination of these pathologies by the single term "metabolic syndrome X".

scholarly journals Rhino-orbital COVID-19 associated mucormycosis- A case report

2021 ◽  
Vol 7 (4) ◽  
pp. 304-307
Author(s):  
Shanmuga Vadivoo Natarajan ◽  
B Usha
Keyword(s):  
Diabetes Mellitus ◽  
Infectious Disease ◽  
Case Report ◽  
Tertiary Care ◽  
Notifiable Disease ◽  
Health Ministry ◽  
First Case ◽  
Uncontrolled Diabetes ◽  
History Of ◽  
Second Wave

COVID-19 Associated Mucormycosis (CAM) is an emerging infectious disease that has caused increased mortality & morbidity in India during this second wave of the pandemic. The country has reported more than 30,000 cases and over 2,000 deaths by Mucormycosis so far, according to sources from Union Health Ministry. CAM is now a notifiable disease. At our Tertiary care teaching hospital, which caters for COVID 19 management, we are reporting the first case of Rhino orbital CAM, which was caused by Rhizopus spp. Our patient had a history of contact with a suspected COVID 19 patient and was recently diagnosed with uncontrolled diabetes mellitus. A direct KOH microscopic examination of purulent material aspirated from the sinonasal polyp of the patient revealed fungal elements, and Rhizopus spp was isolated. Due to a shortage of Amphotericin B, the patient was referred to a government higher speciality centre for further management. The patient was followed up & was noted that he was treated with antifungal and discharged following recovery.

Review on Mucormycosis

2021 ◽  
Vol 9 (07) ◽  
pp. 401-407
Author(s):  
Deepthi Somarouthu ◽  
Vasantha Thota ◽  
Kalyani Ampolu
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Bone Marrow ◽  
Species Level ◽  
Tissue Necrosis ◽  
Uncontrolled Diabetes ◽  
Life Threatening ◽  
Anti Fungal ◽  
Pcr Targeting ◽  
Nose And Throat

Mucormycosis is a opportunistic fungal infection that occurs in patients who are immunocompramised. The fungus causing mucormycosis belongs to the class of zygomycetes and the order of mucorales. It is highly life-threatening mycotic infection that is characterised by angioinvasion, infarction, and tissue necrosis. The risk factors include uncontrolled diabetes mellitus in ketoacidosis, various forms of metabolic acidosis, treatment with corticosteroids, organ or bone marrow transplantation etc. The diagnosis is challenging and treatment should start as early as possible to decrease mortality. Diagnosis is based on symptoms such as, in case of sinusitis, sinus biopsies are required. Ear, nose and throat endoscopy should be done. Molecular identification of mucormycosis can help in confirming diagnosis and identify the fungus from genus to species level. Different techniques are as follows: DNA probes targeting 18S subunit, ITS1 sequencing after PCR with pan-fungal primers, 18S-targeted semi-nested PCR and real time PCR targeting cytochrome b gene. The therapeutic approach should be multimodal including anti-fungal agents, surgical debridement, and correction of underlying symptoms predisposing the patient to disease.

scholarly journals Cerebral Coenurosis Masquerading as Malignancy: A Rare Case Report from India

2019 ◽  
Vol 10 (02) ◽  
pp. 367-370
Author(s):  
Shamila Mohamed Ali ◽  
P. Somashekara Reddy ◽  
S. Venugopal ◽  
Manmeet Chhabra ◽  
Anita Mahadevan
Keyword(s):  
Case Report ◽  
Characteristic Feature ◽  
Rare Case ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Hydatid Cysts ◽  
The Third ◽  
Rare Case Report ◽  
Cerebral Coenurosis ◽  
Cuticular Layer

ABSTRACTHuman coenurosis is a rare zoonotic disease caused by the larvae of Tinea multiceps seen in sheep-rearing countries. We report the case of a 63-year-old male who was referred to our hospital with a working diagnosis of skull base chondrosarcoma. Histopathological examination after surgical excision revealed characteristic feature of coenurus with multiple scolices invaginating from the outer cuticular layer. Coenuri are often mistaken for giant cysticercal cysts and hydatid cysts. Despite its wide prevalence in cattle, only two cases of human coenurosis are reported from India till date. We report the third case from India.

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