ANTI-ULCER ACTIVITY OF ETHANOLIC SARCOSTEMMA ACIDUM STEM EXTRACT

Morus alba stem extract possesses several biological activities. However, skin delivery of the extract is limited by the stratum corneum. In this study, lamellar lyotropic liquid crystal (LLC) was investigated for the potential application in the skin delivery of M. alba stem extract. The four formulations were developed and incorporated with M. alba stem extract at 3% w/w. These formulations were stored at room temperature in light-protected containers for 3 months. The optical pattern under polarized light microscope, viscosity and remaining of the extract were determined. The skin penetration enhancing property of the formulations was investigated using excised porcine ear skin model. The results showed that all formulations remained stable after 3-month storage. The two formulations exhibiting good penetration enhancing properties were F3 consisting of PEG-7 glyceryl cocoate/n-Dodecane/Water/extract (55.29/19.40/22.31/3.00 %w/w) and F4 consisting of mixed Surfactant/n-Dodecane/Water/extract (48.50/4.85/43.65/3.00 %w/w). The mixed surfactant composed of PEG-7 glyceryl cocoate/PEG-40 hydrogenated castor oil/Glyceryl oleate (40/33.24/26.76 %w/w). It can be concluded that the lamellar LLC formulations developed in this study can be used as a carrier for delivering of M. alba stem extract. The components of the formulations which play important roles are the oil and the surfactant.

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Gnidia glauca Leaf and Stem Extract Mediated Synthesis of Gold Nanocatalysts with Free Radical Scavenging Potential

Journal of Nanomedicine & Nanotechnology ◽

10.4172/2157-7439.1000358 ◽

2016 ◽

Vol 07 (02) ◽

Cited By ~ 9

Author(s):

Sougata Ghosh ◽

Sumersing Patil

Keyword(s):

Free Radical ◽

Radical Scavenging ◽

Free Radical Scavenging ◽

Stem Extract

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The Resistance of Bandotan (Ageratum Conyzoides) Leaf Extract and Siwak Stem Extract on the Growth of Butterial Streptococcus Mutans

Journal of Physics Conference Series ◽

10.1088/1742-6596/1477/6/062027 ◽

2020 ◽

Vol 1477 ◽

pp. 062027

Author(s):

H Lesmana ◽

M Saleh ◽

E Thioritz ◽

H Miko ◽

Y Sopianah

Keyword(s):

Streptococcus Mutans ◽

Leaf Extract ◽

Ageratum Conyzoides ◽

Stem Extract

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Alcoholic Stem Extract ofCoscinium fenestratumRegulates Carbohydrate Metabolism and Improves Antioxidant Status in Streptozotocin–Nicotinamide Induced Diabetic Rats

Evidence-based Complementary and Alternative Medicine ◽

10.1093/ecam/neh099 ◽

2005 ◽

Vol 2 (3) ◽

pp. 375-381 ◽

Cited By ~ 54

Author(s):

I. R. Punitha ◽

K. Rajendran ◽

Arun Shirwaikar ◽

Annie Shirwaikar

Keyword(s):

Carbohydrate Metabolism ◽

Antioxidant Status ◽

Diabetic Rats ◽

Antidiabetic Activity ◽

Glutathione Synthetase ◽

Alcoholic Extract ◽

Enzymatic Antioxidants ◽

Stem Extract ◽

Gluconeogenic Enzyme ◽

Glucose 6 Phosphate Dehydrogenase

Alcoholic extract of the stems ofCoscinium fenestratum, a medicinal plant indigenous to India and Sri Lanka used in ayurveda and siddha medicine for treating diabetes, was studied for its carbohydrate metabolism effect and antioxidant status in streptozotocin–nicotinamide induced type 2 diabetic rats. Oral administration ofC. fenestratumstem extract in graded doses caused a significant increase in enzymatic antioxidants such as catalase, superoxide dismutase, glutathione synthetase, peroxidase, and glutathione peroxidase and in the nonenzymatic antioxidants ascorbic acid, ceruloplasmin and tocopherol. Effects of alcoholic extract on glycolytic enzymes such as glucose-6-phosphate dehydrogenase, lactate dehydrogenase and hexokinase showed a significant increase in their levels, whereas a significant decrease was observed in the levels of gluconeogenic enzyme, glucose-6-phosphatase and alanine aminotransferase in treated diabetic rats. Serum creatinine and urea levels also declined significantly. This investigation demonstrates significant antidiabetic activity ofC. fenestratum.

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Antioxidant Activities of the Aqueous Extracts of Pedalium murex D. Royen EX L. Fruit and Leafy Stem

European Journal of Medicinal Plants ◽

10.9734/ejmp/2021/v32i830406 ◽

2021 ◽

pp. 1-9

Author(s):

Gerard Bessan Dossou-Agoin ◽

Habib Ganfon ◽

Fidèle Assogba ◽

Adam Gbankoto ◽

Joachim Gbenou ◽

...

Keyword(s):

Hydrogen Peroxide ◽

Lipid Peroxidation ◽

Antioxidant Activity ◽

Reducing Power ◽

Total Phenolic ◽

Scavenging Activity ◽

Aqueous Extracts ◽

Fruit Extract ◽

Stem Extract ◽

Dpph Scavenging

Aims: The leafy stem and fruit of P.murex have been reported to be used in folk medicine to treat male reproductive system ailments. This study was undertaken to assess the antioxidant potential of the aqueous extracts of P.murex leafy stem and fruit. Methodology: Extracts were prepared by macerating the powder in water. Total phenolics amount were determined by Folin-Ciocalteu reagent, flavonoids were quantified by aluminum chloride method and total tannin content was estimated by hexacyanoferric method. The in vitro antioxidant activity of the extracts were assessed through 2,2´-diphenyl-1-picrylhydrazyl (DPPH) scavenging assay, reducing power assay, hydrogen peroxide (H2O2) inhibition assay and lipid peroxidation assay. Results: Total phenolic compounds, flavonoids and tannins content were respectively equal to 48.91± 1.67 µg/mg Gallic Acid Equivalents (GAE); 56.01± 0.90 µg/mg Rutin Equivalents (RUE); 16.92± 1.22 µg/mg Tannic Acid Equivalents (TAE) for the leafy stem extract while they were equal to 26.26± 0.54 µg/mg GAE; 47.88± 2.39 µg/mg RUE; 7.94± 0.31 µg/mg TAE for the fruit. The leafy stem extract exhibited a more pronounced DPPH scavenging activity, reducing power, hydrogen peroxide scavenging activity and lipid peroxidation activity than the fruit extract. Conclusion: The antioxidant activity of the leafy stem aqueous extract was significantly more potent than that of the fruit extract. Further studies will find out the extracts pharmacological efficacy and innocuity.

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Substitution of Chemical Fertilizer Using Natural Hormone and Cow Biourine On Growth and Yield of Shallot (Allium Cepa L.)

Proceeding International Conference on Science and Engineering ◽

10.14421/icse.v3.466 ◽

2020 ◽

Vol 3 ◽

pp. 43-47

Author(s):

Lagiman ◽

Ihvan Mei Nugraha ◽

Ami Suryawati ◽

Supono Budi Sutoto

Keyword(s):

Block Design ◽

Chemical Fertilizer ◽

Coconut Water ◽

Growth And Yield ◽

Control Group ◽

Fertilizer Treatment ◽

Chemical Fertilizers ◽

Natural Hormone ◽

Stem Extract ◽

Banana Stem

The use of natural hormone of sprout extract, coconut water, and banana stem extract and application of cow biourine has been introduced as an innovation to reduce the use of chemical fertilizers to increase the productivity of shallot. This study aims to compare the growth and yield of shallot with chemical fertilizer treatment and that of shallot treated with combination of natural hormone and cow biourine. The study was conducted in Temon Wetan, Temon, Kulon Progo, Special Region of Yogyakarta using a Complete Randomized Block Design, which consists of two factors and one control (chemical fertilizer). The first factor is a natural hormone: sprout extract, banana stem extract and coconut water. The second factor is the concentration of cow biourine: 30%, 40%, and 50%. Data were analyzed using diversity at 5% level, Orthogonal Contras at 5% level and DMRT Test with 5% level. It was revealed that the control group with a combined treatments was not significantly different from the growth and yield of shallot of the group with chemical fertilizers. Types of treatments with natural hormone and cow biourine concentrations provided the same growth and yield as that of chemical fertilizer.

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