Recent Development and Validation of Bisacodyl Analysis Method in Tablet with Absorbance Method and Area under Curves Method in Ultraviolet Spectrophotometry

2021 ◽  
pp. 59-67
Author(s):  
Harrizul Rivai ◽  
Nia Pratama ◽  
Ridho Asra
Keyword(s):  
Analysis Method ◽  
Ultraviolet Spectrophotometry ◽  
Development And Validation

scholarly journals Development and Validation of Rapid Analysis Method for Multi-Class Veterinary Drugs in Livestock Products by LC-MS/MS

2012 ◽  
Vol 53 (5) ◽  
pp. 243-253 ◽  
Author(s):  
Takayuki NAKAJIMA ◽  
Chieko NAGANO ◽  
Takeo SASAMOTO ◽  
Hiroshi HAYASHI ◽  
Maki KANDA ◽  
...  
Keyword(s):  
Rapid Analysis ◽  
Veterinary Drugs ◽  
Analysis Method ◽  
Livestock Products ◽  
Development And Validation

scholarly journals Method Development and Validation of Montelukast in API and Pharmaceutical Dosage Form by UV Spectrophotometry

2021 ◽  
Vol 71 (2) ◽  
Author(s):  
Abhishek Chandola ◽  
Meenakshi Bhatt
Keyword(s):  
Dosage Form ◽  
Method Development ◽  
Correlation Coefficients ◽  
Uv Spectrophotometry ◽  
Analysis Method ◽  
Allowable Limit ◽  
Pharmaceutical Dosage Form ◽  
Pharmaceutical Dosage Forms ◽  
Method Development And Validation ◽  
Development And Validation

The present work is done to develop a new simple, rapid, specific, accurate and precise UV spectrophotometric method for Montelukast as API and in pharmaceutical dosage form. The validation of the proposed method was carried out according to the I.C.H guidelines. The wavelength maxima was found 270nm and calibration curves were obtained in the concentration range 5-45?g/ml for montelukast with good correlation coefficients (r2=0.9994.). The precisions of the new method for montelukast was less than the maximum allowable limit (%RSD <2.0) specified by the ICH. Therefore, the method was found to be an accurate, reproducible and sensitive for analysis of montelukast as standard, pharmaceutical dosage forms, and other routine analysis method.

Development and Validation of Analytical Method for Simultaneous Estimation of Diclofenac Sodium and Ofloxacin in Bulk and Ophthalmic Formulations using UV–Visible Spectrometry

2011 ◽  
Vol 4 (2) ◽  
pp. 1399-1402
Author(s):  
Chawla P ◽  
Kumar S ◽  
Sahni V ◽  
Mamman K ◽  
S A Saraf
Keyword(s):  
Diclofenac Sodium ◽  
Simultaneous Equation ◽  
Simultaneous Equations ◽  
Simultaneous Estimation ◽  
Analysis Method ◽  
Q Value ◽  
Value Analysis ◽  
Uv Visible ◽  
Development And Validation ◽  
Validation Of Analytical Method

Two simple, accurate, precise, reproducible, requiring no prior separation and economical procedures for simultaneous estimation of diclofenac sodium and ofloxacin in bulk and ophthalmic formulations have been developed. The first method employs formation and solving of simultaneous equations using 273 nm and 291 nm as two analytical wavelengths for both drugs in acidic methanol. The second method is the Q value analysis based on measurements of absorptivity at 263 nm (as an iso-absorptive point) and 273 nm. Diclofenac sodium and ofloxacin at their respective λmax 273 nm and 291 nm and at isoabsorptive point 263 nm show linearity in a concentration range of 1-20 µg/ml. Recovery studies range from 99.67% for diclofenac sodium and 100.35% for ofloxacin in case of simultaneous equation method and 99.99% for diclofenac sodium and 100.07% for ofloxacin in the case of Q - analysis method confirming the accuracy of the proposed method. In conclusion, the proposed method is recommended for routine analysis since it is rapid, simple, accurate and also sensitive and specific

OS8-7 Development and validation of safety analysis method for HTGR

2006 ◽  
Vol 2006.11 (0) ◽  
pp. 213-216
Author(s):  
Tetsuaki TAKEDA ◽  
Shigeaki NAKAGAWA ◽  
Minoru GOTO ◽  
Kuniyoshi TAKAMATSU
Keyword(s):  
Safety Analysis ◽  
Analysis Method ◽  
Development And Validation
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