Hepatitis B, C, and HIV Infections among blood Donors at Several Hospitals in Lahore, Pakistan

Author(s):  
Shafia Arshad ◽  
Amina Arif ◽  
Rafique Ahmad ◽  
Zeemal Seemab ◽  
Faiqa Shaheen ◽  
...  

The study's objectives are to find out the frequency of hepatitis C, B, and HIV infection among blood donors at different hospitals of Lahore; to understand the relationship of demographic risk factors contributing to the positive cases of hepatitis C, B, and HIV. A cross-sectional study with random sampling in which 200 blood donors participated. A questionnaire was used to record the social and personal practices.  A small percentage of blood donors have a history of jaundice. More than one-fourth had undergone surgical intervention, and more than one-third had suffered a needle stick injury. The vast majority had a history of I/V injections/drips, tooth extraction/dental operations, or both. 10.5% of blood donors were Anti-HBV positive, 12.5% were Anti-HCV positive, and 0.5% were HIV positive. Shaving from community barbers should be avoided. In addition, to overcome hepatitis B, C, and HIV transmission, health education programs should be held among blood donors and the general public to prevent them from infection.

2006 ◽  
Vol 13 (01) ◽  
pp. 23-26
Author(s):  
MUHAMMAD AYUB KHAN ◽  
Muhammad Ashraf ◽  
ABDUL REHMAN ◽  
Azam Ali ◽  
MUHAMMAD ASHRAF ◽  
...  

Objective: To know the prevalence of hepatitis B, hepatitis C and HIV.Design: Observational cross sectional study. Setting: Blood Transfusion Center Tehsil Headquarter HospitalLiaquetpur. Subjects and Methods: The data of blood donors from 2001 to 2003. Results: Total blood donors studiedwere 1426. The prevalence for hepatitis B was 5.96% (CL 4.84%-7.32%) It was 0.07% (CL <0.01% - 0.44%) for HCVand zero for HIV. The prevalence of HBV in males was 6.03% (CL 4.87%-7.45%) while 5.05% (CL 1.91%-11.63%) infemales (p=0. 6917). The prevalence in 17-20 years age group was 6.4% (CL 3.92%-10.23%), 5.81% (CL 4.6%-7.33%)in 21-40 years age group and in 41-60 years age group it was 4.35% (CL 1.33%-28.19%) [p=0.9029]. Conclusion:Hepatitis B is common, hepatitis C is an uncommon health problem while HIV is not present in this area.


2016 ◽  
Vol 2 (1) ◽  
pp. 13-16
Author(s):  
Sabina Rai ◽  
Pranita Dongol ◽  
Hemanta Khanal

Hepatitis B and Hepatitis C are the chronic viral infection that might be transmitted by blood transfusion. Nepal is known to have lowest seroprevalence in Asia. The main objective of the present study is to find out the prevalence of hepatitis B and Hepatitis C and their co-infection among blood donors during study period from March to August 2014. This was a cross sectional study among volunteer blood donors in Dharan who had donated the Blood. A total of 4930 donated blood samples were collected and screened for hepatitis B and hepatitis C by using a rapid enzyme immunoassay (EIA) technique. Among 4930 blood samples under study, the overall seroprevalence of hepatitis B were 0.22% (11 out of 4930) and hepatitis C were 0.39% (19 out of 4930) (P value = 0.01) and the prevalence being lower in females than males for both cases. Hepatitis B were more in age group of 21 -30 (0.4%) but hepatitis C in age group of 31-40 (0.5%). Hepatitis B and C are potential threats to be transmitted from unscreened blood.Sunsari Technical College Journal 2015, 2(1):13-16


PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261155
Author(s):  
Alexander Nersesov ◽  
Arnur Gusmanov ◽  
Byron Crape ◽  
Gulnara Junusbekova ◽  
Salim Berkinbayev ◽  
...  

Background & aims Kazakhstan has implemented comprehensive programs to reduce the incidence of Hepatitis B and Hepatitis C. This study aims to assess seroprevalence and risk factors for HBsAg and anti-HCV positivity in three large regions of Kazakhstan. Methods A cross-sectional study was conducted in three regions geographically remote from each other. Participants were randomly selected using a two-stage stratified cluster sampling and were surveyed by a questionnaire based on the WHO STEP survey instrument. Blood samples were collected for HBsAg and anti-HCV testing. Results A total of 4,620 participants were enrolled. The seroprevalence was 5.5% (95%CI: 3.6%-8.4%) for HBsAg and 5.1% (95%CI: 3.5%-7.5%) for anti-HCV antibodies. Both were more prevalent in the western and northern regions than in the southern. A history of blood transfusion was significantly associated with anti-HCV presence, with odds ratios (ORs) of 2.10 (95%CI: 1.37–3.21) and was borderline associated with HBsAg 1.39 (95%CI: 0.92–2.10), respectively. Having a family member with viral hepatitis was also borderline associated (2.09 (95%CI: 0.97–4.50)) with anti-HCV positivity. Conclusions This study found a high-intermediate level of endemicity for HBsAg and a high level of endemicity for anti-HCV antibodies in three large regions of Kazakhstan. We found that history of surgery was not associated with HbsAg neither with anti-HCV seropositivity rates. Blood transfusion was associated with anti-HCV seropositivity, however, to investigate effectiveness of the introduced comprehensive preventive measures in health care settings, there is a need to conduct further epidemiological studies.


Author(s):  
Matías J. Pereson ◽  
Alfredo P. Martínez ◽  
Katia Isaac ◽  
Gustavo Laham ◽  
Ezequiel Ridruejo ◽  
...  

Introduction. Blood-borne infections are a major cause of harm in individuals on haemodialysis (HD). In particular, knowledge about hepatitis B (HBV), hepatitis C (HCV) and human immunodeficiency virus (HIV) status in HD patients is a major concern, since these infections may cause comorbidities in this setting. There is a paucity of data regarding this issue in Argentina. Hypothesis/Gap Statement. The epidemiological surveillance of HBV, HCV, and HIV is a fundamental tool for planning and implementing health strategies in order to prevent and control viral transmission of these viral agents. Aim. To determine the seroprevalence of HBV, HCV and HIV infections in HD patients in Buenos Aires, Argentina. Methodology. Seven hundred and forty-eight HD patients were included in a retrospective cross-sectional study. Serological assays were performed to determine HBV, HCV and HIV status. HBV HBsAg and anti-HBc IgG were analysed using AxSYM (samples before 2010) or the Architect Abbott system (samples since 2010), anti-HCV IgG testing was performed using the anti-HCV enzyme immunoassay AxSYM HCV V3.0 and ARCHITECT anti-HCV, while HIV was tested for using AxSYM HIV 1/2 gO and ARCHITECT HIV Ag/Ab Combination. HCV genotyping was carried out by phylogenetic analysis of the NS5B partial gene. Results. Infection with one of the viruses was detected in 31.1 % of patients [HBV in 82 (11.0 %), HCV in 179 (23.9 %) and HIV in 6 (0.8 %)]. Thirty-two (4.3 %) patients had 2 virus markers [27 (3.6 %) with HCV/HBV, 4 (0.5 %) with HCV/HIV and 1 (0.13 %) with HBV/HIV]. Finally, a single patient (0.13 %) presented all three markers. Time on dialysis was correlated with HCV but not with HBV infection. The HCV subtype distribution in HD patients was inverted with respect to that observed in the general population (HCV-1a 73.2 % and HCV-1b 26.8 % in HD vs HCV-1a 26.5 % and HCV-1b 73.5 % in the general population, P <0.001). Conclusion. Despite the implementation of universal precautionary biosafety standards for dialysis, infection with HBV and HCV continues to occur at very high rates in HD patients. The results emphasize the need to carry out proactive tasks for early diagnosis and treatment of infected individuals and to vaccinate those with non-protective antiHBs antibodies in order to reduce morbidity and mortality in HD patients.


2015 ◽  
Vol 6 (4) ◽  
pp. 213-216 ◽  
Author(s):  
Kashif Ikram ◽  
Humayun Kaleem Siddiqui ◽  
Sana Maqbool ◽  
Maham Altaf ◽  
Sania Khan

ABSTRACT Objective To determine the frequency of needle stick injury in dental practice and to evaluate the level of knowledge, attitude and practices of the dental students and dentists regarding needle stick injuries prevention. Materials and methods This descriptive cross-sectional study was undertaken at eight different institutes of Karachi from July 2014 to March 2015. Data were collected in 800-sample questionnaire forms that comprised of ten questions in English language. Questionnaire was designed to obtain information regarding frequency, awareness and prevention of needle stick injury. Data were entered and analyzed in Statistical Package for the Social Sciences (SPSS) Version 20. Result A total of 800 samples were returned with a 100% response rate. About 73% participants gave a history of needle stick injury during practice. Of these 42% were the house officers. It was reported that knowledge regarding vaccination against hepatitis B was prevalent among participants. Most of the participants agreed that they have received guidelines regarding prevention and protection from needle stick injury. Conclusion It was concluded from this study that hepatitis B vaccination is necessary to prevent needle stick injury and proper instruments/guidelines should be given to all health related professionals in order to minimize the risk of bloodborne infections through needle stick injury. How to cite this article Ikram K, Siddiqui HK, Maqbool S, Altaf M, Khan S. Frequency of Needle Stick Injury among Dental Students and Dentists of Karachi. World J Dent 2015;6(4): 213-216.


2020 ◽  
Author(s):  
Matias Javier Pereson ◽  
Alfredo Martinez ◽  
Katia Isaac ◽  
Gustavo Laham ◽  
Ezequiel Ridruejo ◽  
...  

Background and Aim: Blood-borne infections are a major cause of damage in individuals on hemodialysis (HD). In particular, knowledge about the viral status of hepatitis B (HBV), hepatitis C (HCV) and human immunodeficiency virus (HIV) in HD patients is gold data to face medical challenges. Related information is scarce in Argentina. The aim of this study was to determine the prevalence of HBV, HCV and HIV infections in HD patients from Buenos Aires, Argentina. Methods: Seven hundred and forty-eight HD patients were included in a retrospective cross-sectional study. Laboratories assays were performed to determine virological status. HCV genotyping was carried out by phylogenetic analysis of NS5B partial gene. Results: Infection with one of the viruses was detected in 31.1% of patients [HBV in 82 (11.0%), HCV in 179 (23.9%), and HIV in 6 (0.8%)]. Thirty-two (4.3%) patients had two virus markers [27 (3.6%) with HCV/HBV, 4 (0.5%) with HCV/HIV and 1 (0.13%) with HBV/HIV]. Finally, one single patient (0.13%) presented all three markers. Time on dialysis was correlated with HCV infection but no with HBV. Distribution of HCV subtypes was inverted respect to the observed in general population [HCV-1a (73.2%) and HCV-1b (26.8%) in HD vs. HCV-1a (26.5%) and HCV-1b (73.5%) in general population, p<0.001]. Conclusions: These infections, mainly HCV, continue to occur at a very high rate in HD patients. Results emphasize the need to consider a priority the HCV infected patients in dialysis treatment and to vaccine against HBV in order to decrease its morbidity and mortality.


2010 ◽  
Vol 128 (6) ◽  
pp. 320-323 ◽  
Author(s):  
Leila Kasraian ◽  
Alireza Tavasoli

CONTEXT AND OBJECTIVE: Selection of healthy blood donors is essential to ensure blood safety. A confidential self-exclusion (CSE) system was designed so that high-risk donors could confidentially exclude their blood from use in transfusions. This study aimed to compare the demographic characteristics and the results from human immunodeficiency virus (HIV), hepatitis B surface (HBS) and hepatitis C virus (HCV) screening tests on donors who opted to get into and out of CSE. DESIGN AND SETTING: Analytical cross-sectional study on all volunteer donors at Shiraz Blood Transfusion Organization from March 21, 2006, to March 21, 2008. METHODS: The results from the abovementioned tests were compared between donors who opted into and out of CSE. RESULTS: 100,148 donors in 2006 and 104,271 in 2007 gave blood. Among these donors, respectively, 829 (0.82%) and 592 (0.57%) opted for the CSE. The prevalence of HIV antibodies, HBS antigens and HCV antibodies in CSE donors was significantly higher than in donors who did not choose CSE (p < 0.05). The prevalence of at least one of these three infections among CSE donors was 3.12% in 2006 and 3.04% in 2007, and was significantly higher than the prevalence among non-CSE donors (0.58% and 0.57%, respectively). CONCLUSION: Because of the higher prevalence of HBS, HCV and HIV positivity in blood donors who chose the CSE option, offering CSE to blood donors could be a potentially useful method for improving blood safety, since it could increase the detection of infected blood during the window period.


2019 ◽  
Vol 13 ◽  
Author(s):  
Alexandre Lins Werneck ◽  
Thais De Oliveira ◽  
Maria Amélia Zanon Ponce ◽  
Sonia Aparecida Da Cruz Oliveira

Objetivo: determinar a prevalência, o perfil epidemiológico e as características associadas à coinfecção pelos vírus das hepatites A, B, C, sífilis e TB entre indivíduos infectados pelo vírus HIV. Método: trata-se de um estudo quantitativo, descritivo, transversal. Compôs-se a amostra com 161 pacientes, e realizou-se a análise dos dados a partir das informações do prontuário de pacientes coinfectados pelos vírus das hepatites B, C, sífilis e TB entre infectados pelo vírus HIV. Apresentaram-se os resultados em forma de tabelas. Resultados: nota-se que a maioria eram homens (81,37%), na faixa etária de 21 a 40 anos (67,08%), coinfectados (89,90%), solteiros (73,91%), homossexuais (49,69%), com três ou mais parceiros durante a vida (94,64%), sendo pacientes que usaram drogas (86,35%) e os que usam drogas atualmente (64,60%). Relatou-se mais o uso de preservativos como “às vezes” por 81,37% da amostra. Conclusão: concluiu-se que todos os indivíduos infectados pelo vírus HIV apresentam perfil epidemiológico associado aos vírus das hepatites A, B, C, sífilis e TB. Mostrou-se, pela relação de prevalência, que indivíduos coinfectados tendem a possuir sífilis e hepatite B. Descritores: Soropositividade Para HIV; Infecções Oportunistas Relacionadas Com o HIV; Coinfecção Por HIV; Hepatite B; Hepatite C; Sífilis.ABSTRACTObjective: to determine the prevalence, epidemiological profile and characteristics associated with hepatitis A, B, C, syphilis and TB virus coinfection among HIV-infected individuals. Method: this is a quantitative, descriptive, cross-sectional study. The sample consisted of 161 patients, and data analysis was performed based on information from the medical records of patients co-infected with hepatitis B, C, syphilis and TB viruses among those infected with HIV. Results were presented in tables. Results: most of them were men (81.37%), aged between 21 and 40 years (67.08%), co-infected (89.90%), single (73.91%), homosexual ( 49.69%), with three or more partners during life (94.64%), being patients who used drugs (86.35%) and those who currently use drugs (64.60%). Condom use was reported as “sometimes” by 81.37% of the sample. Conclusion: it was concluded that all individuals infected with HIV have an epidemiological profile associated with hepatitis A, B, C, syphilis and TB viruses. The prevalence ratio showed that co-infected individuals tend to have syphilis and hepatitis B. Descriptors: HIV Seropositivity; AIDS-Related Opportunistic Infections; HIV Infections; Hepatitis B; Hepatitis C; Syphilis.RESUMENObjetivo: determinar la prevalencia, el perfil epidemiológico y las características asociadas con la hepatitis A, B, C, la sífilis y la coinfección por el virus de la tuberculosis en personas infectadas por el VIH. Método: este es un estudio cuantitativo, descriptivo, transversal. La muestra consistió en 161 pacientes, y el análisis de datos se realizó con base en la información de los registros médicos de pacientes coinfectados con virus de hepatitis B, C, sífilis y TB entre aquellos infectados con VIH. Los resultados se presentaron en tablas. Resultados: la mayoría de ellos eran hombres (81.37%), con edades comprendidas entre 21 y 40 años (67.08%), coinfectados (89.90%), solteros (73.91%), homosexuales (49.69%), con tres o más parejas durante la vida (94.64%), siendo pacientes que usaron drogas (86.35%) y aquellos que actualmente usan drogas (64.60%). El uso de condones se informó como "a veces" en el 81,37% de la muestra. Conclusión: se concluyó que todas las personas infectadas con VIH tienen un perfil epidemiológico asociado con los virus de la hepatitis A, B, C, sífilis y TB. La razón de prevalencia mostró que las personas coinfectadas tienden a tener sífilis y hepatitis B. Descriptores: Seropositividad Para HIV; Infecciones Oportunistas Relacionadas com el SIDA; Infecciones por VIH; Hepatitis B; Hepatitis C; Sífilis.


Health Scope ◽  
2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Seyed Mohammad Hashemi Shahri ◽  
Fatemeh Ansari-Moghadam ◽  
Alireza Ansari Moghadam

Background: Homeless people are prone to sexually transmitted and blood-borne infectious diseases such as hepatitis B, hepatitis C, and HIV due to their risky behaviors and low awareness of various diseases. Objectives: Thus, the present research aimed to examine the epidemiologic patterns of HBV, HCV, HIV, and related factors among the homeless population of Zahedan in 2019. Methods: A cross-sectional study was conducted on a total of 329 homeless people. Eligible people were selected using a convenience sampling method from homeless individuals residing in care centers affiliated with the Welfare Organization and the Health Deputy of Zahedan University of Medical Sciences. Data on the demographic and behavioral characteristics of the cases were collected through a structured questionnaire completed in face-to-face interviews. A 10 cc blood sample was taken from each of the cases for serological tests of hepatitis B, hepatitis C, and HIV. The test results and collected data were entered in SPSS16 software. Logistic regression analysis and chi-square tests were used to analyze the data. Results: The majority of the cases (84%) were males, and 59% were in the age-group of 35 - 50 years. Of the subjects, 93% had a history of drug abuse, 74% reported a history of smoking, and 45% had tattoos. The prevalence of hepatitis C, hepatitis B, and HIV was 13%, 2.7%, and 0.3%, respectively (only one case of HIV was identified). In a multi-variate model, imprisonment history [OR = 2.32 (1.08 - 4.98)], history of sexual abuse [OR = 3.73 (1.36 - 10.26)], being widowed or divorced [OR = 2.83, (1.21 - 6.64)], and history of injection with shared needles and syringes [OR = 5.11 (1.97 - 13.28)] remained the predicting factors of hepatitis C. Conclusions: Based on the obtained results of the study, homeless people are more prone to infections with HCV, HBV, and HIV due to their risky behaviors. Therefore, a need is highlighted for preventive interventions and developing the level of health literacy in this group regarding behaviors contributing to the aforementioned infections.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Degu Abate Mengiste ◽  
Abebe Tolera Dirbsa ◽  
Behailu Hawulte Ayele ◽  
Tewodros Tesfa Hailegiyorgis

Abstract Background The risk of hepatitis B virus infection among medical waste handlers who undergo collection, transportation, and disposal of medical wastes in the health institutions is higher due to frequent exposure to contaminated blood and other body fluids. There is limited evidence on the seroprevalence of hepatitis B among medical waste handlers in eastern Ethiopia. The study was aimed at studying the seroprevalence of Hepatitis B Virus and associated risk factors among medical waste collectors at health facilities of eastern Ethiopia. Methods A facility-based cross-sectional study was conducted among randomly selected medical waste collectors from public health facilities in eastern Ethiopia from March to June 2018. A pre-tested and well-structured questionnaire was used to collect data on socio-demographic characteristics and hepatitis B infection risk factors. A2.5ml venous blood was also collected, centrifuged and the serum was analyzed for hepatitis B surface antigen using the instant hepatitis B surface antigen kit. Descriptive summary measures were done. Chi-square and Fisher exact tests were used to assess the risk of association. Multivariate logistic regression was conducted with 95% CI and all value at P-value < 0.05 was declared statistically significant. Results From a total of 260 (97.38%) medical waste collectors participated, HBV was detected in 53 (20.4%) of the participants [95%CI; 15.8, 25.6]. No significant differences were observed in the detection rates of HBV with respect to socio-demographic characteristics. In both bivariate and multivariable logistic regression analysis, being unvaccinated (AOR = 6.35; 95%CI = [2.53–15.96], P = 0.001), history of blood transfusion (receiving) (AOR; 3.54; 95%CI; [1.02–12.24], P = 0.046), history of tattooing (AOR = 2.86; 95%CI = [1.12–7.27], p = 0.03), and history of multiple sexual partner (AOR = 10.28; 95%CI = [4.16–25.38], P = 0.001) remained statistically significantly associated with HBsAg positivity. Conclusion This cross-sectional study identified that HBV infection is high among medical waste collectors in eastern Ethiopia. Immunization and on job health promotion and disease prevention measures should be considered in order to control the risk of HBV infection among medical waste collectors in eastern Ethiopia.


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