scholarly journals Positivity of HIV, hepatitis B and hepatitis C in patients enrolled in a confidential self-exclusion system of blood donation: a cross-sectional analytical study

2010 ◽  
Vol 128 (6) ◽  
pp. 320-323 ◽  
Author(s):  
Leila Kasraian ◽  
Alireza Tavasoli

CONTEXT AND OBJECTIVE: Selection of healthy blood donors is essential to ensure blood safety. A confidential self-exclusion (CSE) system was designed so that high-risk donors could confidentially exclude their blood from use in transfusions. This study aimed to compare the demographic characteristics and the results from human immunodeficiency virus (HIV), hepatitis B surface (HBS) and hepatitis C virus (HCV) screening tests on donors who opted to get into and out of CSE. DESIGN AND SETTING: Analytical cross-sectional study on all volunteer donors at Shiraz Blood Transfusion Organization from March 21, 2006, to March 21, 2008. METHODS: The results from the abovementioned tests were compared between donors who opted into and out of CSE. RESULTS: 100,148 donors in 2006 and 104,271 in 2007 gave blood. Among these donors, respectively, 829 (0.82%) and 592 (0.57%) opted for the CSE. The prevalence of HIV antibodies, HBS antigens and HCV antibodies in CSE donors was significantly higher than in donors who did not choose CSE (p < 0.05). The prevalence of at least one of these three infections among CSE donors was 3.12% in 2006 and 3.04% in 2007, and was significantly higher than the prevalence among non-CSE donors (0.58% and 0.57%, respectively). CONCLUSION: Because of the higher prevalence of HBS, HCV and HIV positivity in blood donors who chose the CSE option, offering CSE to blood donors could be a potentially useful method for improving blood safety, since it could increase the detection of infected blood during the window period.

2018 ◽  
Vol 25 (08) ◽  
pp. 1245-1251
Author(s):  
Mustansar Billah ◽  
Syed Muhammad Raza Shah ◽  
Muhammad Mujtaba Hashir

Objectives: To determine the frequency of HBV and HCV among blood donorscoming voluntarily at the blood bank of Ibne- Siena hospital and research centre, Multan,Pakistan, to ascertain the disease burden in the community for their future prevention andcontrol. Study Design: It was a descriptive, cross- sectional study on blood units donated byhealthy individuals coming voluntarily for blood donation, and willing to get their blood testedfor HBV, HCV. Setting: Community medicine department of Multan medical and dental collegeMultan, and blood bank of affiliated tertiary hospital, Ibn-e- Siena hospital Multan. Period: Sixmonths period from Jan 2016 to June 2016. Materials and Methods: Data of the blood donorswas collected. Present study was based on previous well maintained records of hospital bloodbank. During the reported period, a total of 1195 blood donors attended the blood bank, andthey all were screened for HBsAg and anti-HCV. SPSS- 16 was used to analyze the data, fordetermination of frequencies of Hepatitis- B, and C according to the age and gender. Results:Total numbers of blood donors were 1195. 1191 were males, and 4 were females. All thefemales were negative for both HBV, and HCV. Males positive for HBV were 18 (1.5 %), andthose Positive for HCV were 27 (3.2%).


2006 ◽  
Vol 13 (01) ◽  
pp. 23-26
Author(s):  
MUHAMMAD AYUB KHAN ◽  
Muhammad Ashraf ◽  
ABDUL REHMAN ◽  
Azam Ali ◽  
MUHAMMAD ASHRAF ◽  
...  

Objective: To know the prevalence of hepatitis B, hepatitis C and HIV.Design: Observational cross sectional study. Setting: Blood Transfusion Center Tehsil Headquarter HospitalLiaquetpur. Subjects and Methods: The data of blood donors from 2001 to 2003. Results: Total blood donors studiedwere 1426. The prevalence for hepatitis B was 5.96% (CL 4.84%-7.32%) It was 0.07% (CL <0.01% - 0.44%) for HCVand zero for HIV. The prevalence of HBV in males was 6.03% (CL 4.87%-7.45%) while 5.05% (CL 1.91%-11.63%) infemales (p=0. 6917). The prevalence in 17-20 years age group was 6.4% (CL 3.92%-10.23%), 5.81% (CL 4.6%-7.33%)in 21-40 years age group and in 41-60 years age group it was 4.35% (CL 1.33%-28.19%) [p=0.9029]. Conclusion:Hepatitis B is common, hepatitis C is an uncommon health problem while HIV is not present in this area.


2016 ◽  
Vol 2 (1) ◽  
pp. 13-16
Author(s):  
Sabina Rai ◽  
Pranita Dongol ◽  
Hemanta Khanal

Hepatitis B and Hepatitis C are the chronic viral infection that might be transmitted by blood transfusion. Nepal is known to have lowest seroprevalence in Asia. The main objective of the present study is to find out the prevalence of hepatitis B and Hepatitis C and their co-infection among blood donors during study period from March to August 2014. This was a cross sectional study among volunteer blood donors in Dharan who had donated the Blood. A total of 4930 donated blood samples were collected and screened for hepatitis B and hepatitis C by using a rapid enzyme immunoassay (EIA) technique. Among 4930 blood samples under study, the overall seroprevalence of hepatitis B were 0.22% (11 out of 4930) and hepatitis C were 0.39% (19 out of 4930) (P value = 0.01) and the prevalence being lower in females than males for both cases. Hepatitis B were more in age group of 21 -30 (0.4%) but hepatitis C in age group of 31-40 (0.5%). Hepatitis B and C are potential threats to be transmitted from unscreened blood.Sunsari Technical College Journal 2015, 2(1):13-16


Author(s):  
Shahida Amjed Riaz Shah ◽  
Ayesha Ehsan

Introduction: This project was aimed to determine the seropositivity status for Hepatitis B surface antigen (HBsAg), antiHepatitis C (HCV) antibodies and antibodies to Human Immune Deficiency Virus (HIV) I and II in healthy blood donorsdonating blood at Shaikh Zayed Hospital Lahore.Material and Methods: The relevant data was collected during a period of 28 months from 1st January 2006 till 31st March2008. It was a cross sectional study which entailed screening of 60719 healthy donors. The donors were aged between 16years to 45 years. There were 93.43% males and 6.57% females.Results: The seroprevalence of Anti HCV antibodies was 3.870%; for HBsAg it was 1.407%; for HIV antibodies it was0.00658%. Our study demonstrated a higher seropositivity for HIV in healthy donor population than all of the previousreports except one with which it matched precisely. HBsAg showed a definite downwards inclination when compared withsimilar previous studies carried out in the last 7 years. Seroprevalence of anti HCV antibody was found to be similar whencompared with previous studies and demonstrated a higher trend in large cities with a multiethnic population.Key Words: MeSH: Blood donors, seroprevalence, HbsAg, antiHCV, HIV.


Author(s):  
Shafia Arshad ◽  
Amina Arif ◽  
Rafique Ahmad ◽  
Zeemal Seemab ◽  
Faiqa Shaheen ◽  
...  

The study's objectives are to find out the frequency of hepatitis C, B, and HIV infection among blood donors at different hospitals of Lahore; to understand the relationship of demographic risk factors contributing to the positive cases of hepatitis C, B, and HIV. A cross-sectional study with random sampling in which 200 blood donors participated. A questionnaire was used to record the social and personal practices.  A small percentage of blood donors have a history of jaundice. More than one-fourth had undergone surgical intervention, and more than one-third had suffered a needle stick injury. The vast majority had a history of I/V injections/drips, tooth extraction/dental operations, or both. 10.5% of blood donors were Anti-HBV positive, 12.5% were Anti-HCV positive, and 0.5% were HIV positive. Shaving from community barbers should be avoided. In addition, to overcome hepatitis B, C, and HIV transmission, health education programs should be held among blood donors and the general public to prevent them from infection.


2016 ◽  
Vol 4 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Tonmoy Biswas ◽  
Sunil Kumar Biswas ◽  
Tonmoy Biswas

Background: Hepatitis B infection is a global threat for people of all age groups and is common in Bangladesh and other South Asian countries. Blood donors and blood donation can present important risk for hepatitis B infection. Our objective was to identify seroprevalence of hepatitis B virus among blood donors in Faridpur, Bangladesh. Methods: A cross-sectional study was conducted among 719 blood donors in the Faridpur district of Bangladesh from April to July 2013. Data was collected by non-probability convenient sampling maintaining inclusion and exclusion criteria. Face-to-face interview, blood grouping test, and hepatitis B surface antigen (HBsAg) screening were conducted. Results: About 30% of the blood donors were between 19 and 23 years of age, and 87.5% of them were males. Two-thirds (64.1%) of the donors were replacement donors, while the remaining 35.9% of them were voluntary donors. The overall seropositivity of HBsAg was found to be 1.5%. All infected blood donors were males. Hepatitis B infection was more prevalent in the 34–38 years age group and least prevalent among those older than 48 years of age. About 2% of replacement blood donors were infected with hepatitis B virus, compared to 0.7% among voluntary blood donors. Conclusion: Hepatitis B infection among blood donors is relatively lower than in other high-risk groups for hepatitis B infection in Bangladesh. Predominance of HBsAg among older adult groups, replacement donors, and the male gender can be a matter of public health concern.


2015 ◽  
Vol 8 (4) ◽  
pp. 203 ◽  
Author(s):  
Muhammad Bilal ◽  
Abdul Haseeb ◽  
Ibrahim Zahid ◽  
Sehan Siraj Lashkerwala ◽  
Fawad Saeeduddin ◽  
...  

<p>Introduction<strong>: </strong>Blood donation is necessary in order to maintain an adequate supply of blood to patients who are suffering from any kind of disease or trauma, which requires them to have blood transfusion. Female non-blood donors are generally low in number.<strong> </strong>Therefore, this research was carried out to assess the main reasons behind the lack of blood donations made by females, and their knowledge, attitude and perceptions towards voluntary blood donation.</p> <p>Methodology: A cross-sectional study was conducted on 664 female health professionals, who were selected by non-probability convenience sampling from two tertiary care hospitals. A pretested questionnaire was presented to the sample population, and the data was entered and analyzed on SPSS (V17).</p> <p>Results: 94.6 % were aware with the fact that blood is screened for AIDS, Hepatitis B and C before transfusion. Moreover, 83.7% said that they will only donate blood if a family, relative or friend would need it and similarly 83.4%  suggested that they would donate blood if blood donation camps are arranged in hospital premises. 81.8 % thought that blood donors can contract Hepatitis B after donation where as only 29.5% did not blood due already blood loss in menstrual cycle.<strong></strong></p> <p>Conclusion<strong>: </strong>The participants had adequate knowledge about the benefits of blood donation. The most important reason identified for not donating blood is the lack of facilities within the workplace or lack of approach by responsible authorities. The results of the study may help in minimizing the misconceptions of the participants about blood transfusion, which would increase their contribution towards blood donation.</p>


2018 ◽  
Vol 10 (1) ◽  
pp. e2018041 ◽  
Author(s):  
Arzouma Paul YOODA ◽  
Serge Theophile SOUBEIGA ◽  
Kompingnin Yacouba NEBIE ◽  
Birama DIARRA ◽  
Salam SAWADOGO ◽  
...  

Background and ObjectiveThe improved performance of serological tests has significantly reduced the risk of human immunodeficiency and hepatitis B and C viruses transmission by blood transfusion, but there is a persistence of residual risk. The objective of this study was to evaluate the impact of multiplex PCR in reducing the risk of residual transmission of these viruses in seronegative blood donors in Burkina Faso.MethodsThis cross-sectional study was conducted from March to September 2017. The serological tests were performed on sera using ARCHITECTSR i1000 (Abbot diagnosis, USA). Detection of viral nucleic acids was performed by multiplex PCR on mini-pools of seronegative plasma for HBV, HCV and HIV using SaCycler-96 Real Time PCR v.7.3 (Sacace Biotechnologies). Multiplex PCR-positive samples from these mini-pools were then individually tested by the same method.Results A total of 989 donors aged 17 to 65 were included in the present study. "Repeat donors" accounted for 44.79% (443/989). Seroprevalences for HIV, HBV, and HCV were 2.53% (25/989), 7.28% (72/989) and 2.73% (27/989), respectively. Of the 14 co-infections detected, HBV/HCV was the most common with 0.71% (7/989) of cases. Of 808 donations tested by multiplex PCR, 4.70% (38/808) were positive for HBV while no donation was positive for HIV or HCV.Conclusion: Our study showed a high residual risk of HBV transmission through blood transfusion. Due to the high prevalence of blood-borne infections in Burkina Faso, we recommend the addition of multiplex PCR to serologic tests for optimal blood donation screening.


2017 ◽  
Vol 11 (1) ◽  
pp. 34-42 ◽  
Author(s):  
Farahnaz Joukar ◽  
Fariborz Mansour-Ghanaei ◽  
Mohammad Reza Naghipour ◽  
Tolou Hasandokht

Background: Health care workers (HCWs) represent high risk population for viral hepatitis infection. Objectives: This study sought to assess the knowledge of HCWs regarding hepatitis B (HBV) and hepatitis C (HCV) infection. Methods: In a multi-center cross sectional study, all HCWs from eight teaching hospitals were invited to participate in the study and to fill in a self-administered questionnaire. Results: A total of 1008 eligible HCWs have responded to the study. A high proportion of the study participants (55.4% and 52.9%) had unsatisfactory knowledge about HBV and HCV. Mean knowledge score toward HBV was significantly higher among more educated staff, p <0.001 and vaccinated personnel, P=0.02. Majority of responders answered correctly to transmission questions toward HBV and HCV (90% and 80%, respectively). There was statistically significant difference in only transmission domain score between various hospitals (p<0.05). The highest scores were related to surgical hospital. Conclusion: Although more than ninety percent of our participants were educated about HBV and HCV, knowledge about nature of disease, prevention, treatment and vaccine availability was unsatisfactory. Continuous training program toward viral infection is a matter of necessity.


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