Estimation of Variations in the Erythrocyte Sedimentation Rate in COVID-19 Recovered Patients

Background: A cluster of patients with pneumonia and severe acute respiratory syndrome developed in Wuhan, China in December 2019, and infection with a novel coronavirus virus called COVID -19 was later verified. Although fever and cough were the most common early signs and symptoms of COVID -19, extrapulmonary symptoms have also been reported. Many studies demonstrate that called COVID -19 swiftly progresses to acute respiratory distress syndrome and even multiple organ dysfunction. Aim:The study aims to evaluate the erythrocyte sedimentation rate count in COVID -19 recovered individuals and compare it with healthy controls. Materials & Methods: A cross-sectional pilot study in 5 healthy COVID -19 uninfected and 5 COVID -19 recovered individuals was conducted, the blood samples were collected and the erythrocyte sedimentation rate was calculated for each set of controls and samples. Statistical analysis was performed using SPSS software. An independent t-test was done to compare the results. Results: The mean value of the control participants was found to be 8.08 ± 4.38 and the mean value of COVID -19 recovered patients was 20.60 ± 1.81. The difference in Erythrocyte Sedimentation Rate (ESR) values between control individuals and COVID -19 recovered patients was statistically significant with p value of less than 0.005. Conclusion: Within the limitations of the study, we conclude that the COVID -19 recovered patients has higher ESR values compared to the healthy uninfected individuals.

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A comparison of erythrocyte sedimentation rates of bloods anticoagulated with trisodium citrate and EDTA among TB presumptive patients at the University of Gondar comprehensive specialized hospital, northwest Ethiopia

10.21203/rs.2.16918/v3 ◽

2020 ◽

Author(s):

Zegeye Getaneh ◽

Fekadu Ayelgn ◽

Geletaw Asemahegn ◽

Habtamu Geleta ◽

Aregawi Yalew ◽

...

Keyword(s):

Erythrocyte Sedimentation Rate ◽

Sedimentation Rate ◽

Sodium Citrate ◽

Trisodium Citrate ◽

Northwest Ethiopia ◽

Cross Sectional ◽

Erythrocyte Sedimentation ◽

Significant Difference ◽

The Mean ◽

The University

Abstract Objective: The purpose of this study was comparing the erythrocyte sedimentation rate (ESR) results of trisodium citrate (TSC) and ethylene diamine tetra-acetic acid (EDTA) anticoagulants. A comparative cross-sectional study was conducted at the University of Gondar specialized referral hospital, northwest, Ethiopia. A total of 70 TB presumptive participants were recruited. From each of the 70 participants of the study, 3 and 1.6 ml of blood was collected in EDTA tubes and 0.4 ml of trisodium Citrate anticoagulant containing test tubes, respectively. Results: The mean ± SD values of ESR were 57.9 ± 41.45 mm/hr in EDTA and 50.99 ± 43.5 mm/hr in TSC anticoagulated blood. The mean difference of ESR values between EDTA and TSC blood (6.91 ± 13.66 mm/hr) was statistically significant. The Mean ± SD of ESR values using EDTA and TSC in males were 59.57 ± 42.31 and 53.57 ± 44.61 mm/hr while for females it was 54.71±40.44 and 46.04 ± 41.82 mm/hr, respectively. The study indicated that there was a significant difference between ESR values with EDTA and tri-sodium citrate anticoagulants. Keywords: Erythrocyte sedimentation rate, EDTA, Tri-sodium citrate, Westergren Method, Comparison

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Comparison of erythrocyte sedimentation rate between blood anticoagulated with sodium citrate and EDTA among Tuberculosis suspected patients at University of Gondar Hospital, North West Ethiopia

10.21203/rs.2.16918/v2 ◽

2019 ◽

Author(s):

Zegeye Getaneh ◽

Fekadu Ayelgn ◽

Geletaw Asemahegn ◽

Habtamu Geleta ◽

Aregawi Yalew ◽

...

Keyword(s):

Erythrocyte Sedimentation Rate ◽

Sedimentation Rate ◽

Sodium Citrate ◽

Northwest Ethiopia ◽

Cross Sectional ◽

North West ◽

Erythrocyte Sedimentation ◽

Significant Difference ◽

The Mean ◽

Study Participants

Abstract Objective: The purpose of this study was comparison of erythrocyte sedimentation rate results of sodium citrate and ethylene diamine tetra-acetic acid anticoagulant. A comparative cross-sectional study was conducted at University of Gondar Referral Hospital, Northwest, Ethiopia. A total of 70 TB suspected study participants were recruited. From each study participants, 3ml blood was collected in to EDTA tube and 1.6ml blood was collected in to a test tube containing 0.4ml Sodium Citrate anticoagulant. Results: The mean ± SD values for ESR were 57.9 ± 41.45 in EDTA and 50.99 ± 43.5 in citrate anticoagulated blood. The mean difference of ESR values between EDTA and citrated blood was 6.91 ± 13.66 mm/hr with a significant difference. The mean ± SD of ESR for EDTA and citrate blood was 59.57 ± 42.31 and 54.71 ± 40.44 mm/hr for males and 53.57 ± 44.61 and 46.04 ± 41.82 mm/hr for females, respectively. This study indicated that there was a significant difference between ESR values with EDTA and tri-sodium citrate anticoagulants.

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A comparison of erythrocyte sedimentation rates of bloods anticoagulated with trisodium citrate and EDTA among TB presumptive patients at the University of Gondar comprehensive specialized hospital, northwest Ethiopia

10.21203/rs.2.16918/v4 ◽

2020 ◽

Author(s):

Zegeye Getaneh ◽

Fekadu Ayelgn ◽

Geletaw Asemahegn ◽

Habtamu Geleta ◽

Aregawi Yalew ◽

...

Keyword(s):

Erythrocyte Sedimentation Rate ◽

Sedimentation Rate ◽

Sodium Citrate ◽

Trisodium Citrate ◽

Northwest Ethiopia ◽

Cross Sectional ◽

Erythrocyte Sedimentation ◽

Significant Difference ◽

The Mean ◽

The University

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Is Vision C interchangeable with the modified Westergren method for the erythrocyte sedimentation rate?

Turkish Journal of Biochemistry ◽

10.1515/tjb-2020-0090 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Serpil Erdogan ◽

Ridvan Firat ◽

Gamze Avcioglu ◽

Gulsen Yilmaz ◽

Ozcan Erel ◽

...

Keyword(s):

Quality Control ◽

Erythrocyte Sedimentation Rate ◽

Sedimentation Rate ◽

Room Temperature ◽

Temperature Correction ◽

Mean Difference ◽

Automated System ◽

Cross Sectional ◽

Erythrocyte Sedimentation ◽

The Mean

Abstract Objectives As one of the most widely used tests, the erythrocyte sedimentation rate (ESR) is a measurement of sedimentation reaction in blood samples. Although the recommended method for ESR measurement is the Westergren method, this method has some disadvantages in comparison with automated ESR systems. In this cross-sectional study, we aimed to compare Vision c with the Westergren method. Methods The Vision c automated ESR system and the modified Westergren method were compared using K3EDTA-containing tubes and citrated blood tubes from randomly selected 100 patients. Precision, bias, and interference calculations were performed. Results The mean difference between the Vision c (room temperature) and the modified Westergren method was 22.8 ± 26.6 mm/h (95% CI for the mean was 17.50–28.08 mm/h). The mean difference between the Vision c (18 °C) and the modified Westergren method was 27.4 ± 30.6 mm/h (95% CI for the mean was 21.3–33.5 mm/h). The calculated regression analysis equation was “y= 0.263 + 1.053x” and “y= −0.530 + 0.851x” for the Vision c (room temperature) and the Vision c (18 °C), respectively. The imprecision values ranged at 7.55–17.09%. According to our external quality control results, bias was 11.11 and 9.66 for the low- and high-level samples, respectively. Conclusions The Vision c automated ESR system has a comparable analytical performance with the modified Westergren method. The Vision c automated system may be utilized in ESR measurements with quality control evaluations. Nevertheless, temperature correction using Manley’s monogram causes an important negative bias and should be taken into consideration during the evaluation of the Vision c results.

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A comparison of erythrocyte sedimentation rate between blood anticoagulated with sodium citrate and EDTA among Tuberculosis suspected patients at University of Gondar Hospital, North West Ethiopia

10.21203/rs.2.16918/v1 ◽

2019 ◽

Author(s):

Zegeye Getaneh ◽

Fekadu Ayelgn ◽

Geletaw Asemahegn ◽

Habtamu Geleta ◽

Aregawi Yalew ◽

...

Keyword(s):

Erythrocyte Sedimentation Rate ◽

Sedimentation Rate ◽

Sodium Citrate ◽

Northwest Ethiopia ◽

Cross Sectional ◽

North West ◽

Erythrocyte Sedimentation ◽

Significant Difference ◽

The Mean ◽

Study Participants

Abstract Objective: The main aim of this study was comparison of erythrocyte sedimentation rate results of sodium citrate and ethylene diamine tetra-acetic acid anticoagulant. A comparative cross-sectional study was conducted at University of Gondar Referral Hospital, Northwest, Ethiopia. A total of 70 TB suspected study participants were recruited. From each study participants, 3ml blood was collected in to EDTA tube and 1.6ml blood was collected in to a test tube containing 0.4ml Sodium Citrate anticoagulant. Results: The mean ± SD values for ESR were 57.9 ± 41.45 in EDTA and 50.99 ± 43.5 in citrate anticoagulated blood. The mean difference of ESR values between EDTA and citrated blood was 6.91 ± 13.66 mm/hr with a significant difference. The mean ± SD of ESR for EDTA and citrate blood was 59.57 ± 42.31 and 54.71 ± 40.44 mm/hr for males and 53.57 ± 44.61 and 46.04 ± 41.82 mm/hr for females, respectively. This study indicated that there was a significant difference between ESR values with EDTA and tri-sodium citrate anticoagulants.

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A New Case of Schnitzler Syndrome in Bulgaria

Acta Medica Bulgarica ◽

10.2478/amb-2018-0021 ◽

2018 ◽

Vol 45 (2) ◽

pp. 58-62

Author(s):

M. Kirilova-Doneva ◽

M. Kamusheva ◽

S. Donev ◽

I. Popova

Keyword(s):

Erythrocyte Sedimentation Rate ◽

Sedimentation Rate ◽

Time Course ◽

Mean Value ◽

C Reactive Protein ◽

Immunoglobulin Kappa ◽

Reactive Protein ◽

Erythrocyte Sedimentation ◽

Schnitzler Syndrome ◽

The Mean

Abstract We describe the case of a 74-year-old Bulgarian woman with a long history of chronic urticaria with severe burning sensation, arthralgia and fever. Additional symptoms of Schnitzler such as monoclonal immunoglobulin – kappa component, elevated erythrocyte sedimentation rate and enlarged lymph nodes were detected six years after the onset of the symptoms. The first diagnoses hypersensitive vasculitis and dermatitis were established in 2009. Schnitzler syndrome was recognized and the diagnosis was established 2 years later after some examination tests. The time course of the values of IgM, C-reactive protein, erythrocyte sedimentation rate and neutrophils were presented. The mean value of IgM is 13.8 ± 2.19 g/l, the mean value of erythrocyte sedimentation rate is 48.6 ± 14.46 mm/h and the mean value of C-reactive protein – 29.8 ± 7.34 mg/l. The use of nonsteroid anti-inflammatory drugs throughout the period and corticosteroids prescribed parenterally and orally resulted in the relief of arthralgia and fever.

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Can ratio of neutrophil-tolymphocyte count and erythrocyte sedimentation rate in diabetic foot infection predict osteomyelitis and/or amputation?

Hematology Reports ◽

10.4081/hr.2017.6981 ◽

2017 ◽

Vol 9 (1) ◽

Cited By ~ 10

Author(s):

Oktay Yapıcı ◽

Hande Berk ◽

Nefise Öztoprak ◽

Derya Seyman ◽

Alper Tahmaz ◽

...

Keyword(s):

Erythrocyte Sedimentation Rate ◽

Sedimentation Rate ◽

Diabetic Foot ◽

Glycosylated Hemoglobin ◽

Mean Value ◽

Diabetic Foot Infection ◽

Reactive Protein ◽

Erythrocyte Sedimentation ◽

The Mean ◽

Post Hoc

The aim of this study was to search for any relations between the neutrophil-tolymphocyte ratio (NLR) and the development of osteomyelitis and the need for amputation in patients with diabetic foot infection (DFI). All data included DFI patients who were hospitalized in our Infectious Diseases Clinic between 2012 and 2015 and who were classified according to International Classification Disease Code System. 75 patients were analyzed in the study. The DFI patients were stratified into 3 groups of whom had amputation procedure, whom had only debridement/drainage procedure and whom had any surgery procedure. Sidac post hoc analysis was used to perform the effects of NLR, C-reactive protein, erythrocyte sedimentation rate and glycosylated hemoglobin on the surgery procedure status. The DFI patients were also stratified into two another separate group for another analysis to search for the effect of NLR values on the development of osteomyelitis. The mean value of NLR in the amputated patients’ group (15.7±10.3 was significantly higher than those with debridement procedure (9.9±5.6) and those without any surgery (6.0±2.8) (P=0.001). NLR values were also found significantly higher in patients with osteomyelitis in the second analysis (P=0.004). In this study, the NLR was found to have a predictive value on the development of osteomyelitis and on the progression to amputation in patients with DFI.

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Association of Inflammation With Markers of Atherogenicity in Subjects With New-Onset Atria Fibrillation in a Nigerian Community

American Journal of Clinical Pathology ◽

10.1093/ajcp/aqz116.000 ◽

2019 ◽

Vol 152 (Supplement_1) ◽

pp. S80-S80

Author(s):

Constance Nwadike ◽

Amarachi Nwakamma ◽

Harrison Nwanjo ◽

Denis Nwosu ◽

Roy Ezekwe

Keyword(s):

Platelet Count ◽

Prothrombin Time ◽

Erythrocyte Sedimentation Rate ◽

Sedimentation Rate ◽

Serum Lipids ◽

High Density Lipoproteins ◽

Mean Values ◽

Erythrocyte Sedimentation ◽

The Mean ◽

New Onset

Abstract Objectives The evidence supporting the role of circulating markers of inflammation in the pathogenesis of atria fibrillation remains controversial. This study investigated the levels of serum lipids, C-reactive proteins, erythrocyte sedimentation rate, prothrombin time, and platelet count in subjects with new-onset atria fibrillation (NAF), but with no established cardiac disease, in a Nigerian community. Methods The case control study involved a total of 200 subjects: 110 subjects with NAF and 90 apparently healthy subjects without AF, as control. AF was confirmed by a 12-lead electrocardiogram (ECG), while excluding subjects with high risk. Blood samples from the subjects were analyzed for the following parameters: C-reactive proteins using ELISA method and serum lipids using an enzymatic, colorimetric method; erythrocyte sedimentation rate, by Westergreen method; platelet count using a Midray hematology auto analyzer; and the prothrombin time using a tissue thromboplastin method. Data collected from the result were analyzed using SPSS version 15. Results There was a significant increase in the levels of C-reactive proteins and ESR in subjects with NAF when compared with the control subjects. A significant increase was observed in the mean values of total cholesterol and low-density lipoproteins in subjects with NAF, while that of high-density lipoproteins was lower in NAF than in controls. There was no significant difference in the mean values of triglyceride in NAF and the control. Results also showed significantly reduced prothrombin time, with more platelet count in subjects with NAF. The result demonstrated that females (56.3%) had greater risk of developing AF than males (45.8%), while incidence of AF was observed to increase with age. Conclusion The results of the markers assayed suggest marked dyslipidemia, inflammation, and thrombogenesis in subjects with new-onset AF. Hence dyslipidemia and inflammation play critical roles in the pathogenesis of atria fibrillation.

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IVIG Effects on Erythrocyte Sedimentation Rate in Children

International Journal of Pediatrics ◽

10.1155/2014/981465 ◽

2014 ◽

Vol 2014 ◽

pp. 1-4 ◽

Cited By ~ 5

Author(s):

Farhad Salehzadeh ◽

Ahmadvand Noshin ◽

Sepideh Jahangiri

Keyword(s):

Erythrocyte Sedimentation Rate ◽

Sedimentation Rate ◽

Age Groups ◽

The Body ◽

Response To Treatment ◽

Erythrocyte Sedimentation ◽

Neonatal Group ◽

The Mean ◽

Laboratory Tool ◽

To Receive

Background. Erythrocyte sedimentation rate (ESR) is a valuable laboratory tool in evaluation of infectious, inflammatory, and malignant diseases. Red blood cells in outside from the body precipitate due to their higher density than the plasma. In this study we discuss the IVIG effect on ESR in different diseases and different ages.Methods and Materials. Fifty patients under 12 years old who had indication to receive IVIG enrolled in this study. Total dose of IVIG was 2 gr/kg (400 mg/kg in five days or 2 gr/kg in single dose). ESR before infusion of IVIG and within 24 hours after administration of the last dose of IVIG was checked.Results. 23 (46%) patients were males and 27 (54%) were females. The mean of ESR before IVIG was31.8±29.04and after IVIG it was47.2±36.9; this difference was meaningful(P=0.05). Results of ESR changes in different age groups, 6 patients less than 28 days, 13 patients from 1 month to 1 year, 20 patients from 1 to 6 years old, and 11 patients from 6 to 12 years have been meaningful (P=0.001,P=0.025, andP=0.006, resp.).Conclusion. In patients who are receiving IVIG as a therapy, ESR increased falsely (noninflammatory rising); therefore use of ESR for monitoring of response to treatment may be unreliable. Although these results do not apply to neonatal group, we suggest that, in patients who received IVIG, interpretation of ESR should be used cautiously on followup.

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COMPARISON OF RETINAL NERVE FIBER LAYER THICKNESS BETWEEN EMMETROPES AND HIGH MYOPES

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v3i9.514 ◽

2019 ◽

Vol 3 (9) ◽

Author(s):

Neha Yadav

Keyword(s):

High Myopia ◽

Thickness Measurement ◽

Mean Value ◽

Analysis Of Covariance ◽

Field Analysis ◽

P Value ◽

Fiber Layer ◽

Cross Sectional ◽

Rnfl Thickness ◽

The Mean

Background: The present study aims to compare RNFL thickness of high myopes of > - 6D and compare with emmetropic patients, so as to interpret and distinguish the physiological changes of high myopia from accompanying diseases in such individuals. Methods: This was a prospective cross-sectional study. All subjects underwent a full ophthalmic examination, refraction and visual field analysis. Optical coherence tomography was used for RFNL thickness measurement. The mean peripapillary RNFL thickness between groups was compared using both analysis of variance and analysis of covariance. Results: The mean value of average RNFL thickness in both groups was found to be 85.40 in group 1 and 99.34 in group 2. P value was 0.0001, showing that there was significant statistical difference between both the groups and average RNFL thickness was thinner in myopic group. Conclusion: RNFL was found to be significantly thin in high myopia. Keywords: RNFL thickness, Myopia, Emmetropes

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