scholarly journals Dermatofibrosarcoma Protuberans: A Systematic Review of the Literature

2021 ◽  
pp. 885-891
Author(s):  
Alaa Alnooh ◽  
Yasser Al-Qubaisy ◽  
Nujud Alshammari ◽  
Ibrahim Alhowshan
Keyword(s):  
Soft Tissue ◽  
Literature Review ◽  
Clinical Manifestations ◽  
Soft Tissue Sarcomas ◽  
Dermatofibrosarcoma Protuberans ◽  
High Recurrence Rate ◽  
Metastatic Capacity ◽  
High Index Of Suspicion ◽  
Based Medicine ◽  
Slow Growing

Background: Dermatofibrosarcoma Protuberans (DFSP) is a rare slow growing cutaneous soft tissue sarcoma, that is characterized to be locally invasive with high recurrence rate. However, it has poor metastatic capacity. Objective: We are conducting this literature review to gather evidence-based medicine knowledge regarding Dermatofibrosarcoma Protuberans. Moreover, this study highlights the gaps of knowledge in regard to this disease entity. Methods: The literature search was conducted by searching the keywords “Dermatofibrosarcoma Protuberans” and “soft tissue sarcomas” in PubMed and Web of Science databases. Results: 1,769 potentially relevant results showed matched titles, of which 13 articles met the requirements and were included in the literature review. Limitations: Vague nonspecific clinical manifestations, makes it challenging to establish an early diagnosis and seek an appropriate counseling.  In addition, it is difficult to diagnose due to the slow growing behavior and the tumor’s benign appearance. As a result of all of that there is no enough cases reported in the literature. Conclusion: This review highlights the need of high index of suspicion to help reach an early and proper diagnosis and to raise awareness. Dermatofibrosarcoma Protuberans needs a specialized center in order to identify and recognize the disease. The knowledge and awareness of the disease is low since it is rare.

scholarly journals Male urethral sarcoma: a case report and literature review

2015 ◽  
Vol 14 (1) ◽  
pp. 64-66
Author(s):  
Magno Almeida Nogueira ◽  
Guilherme Campelo Lopes dos Santos ◽  
Roberto Iglesias Lopes ◽  
Octavio Henrique Arcos Campos ◽  
Marcos Francisco Dall'Oglio ◽  
...  
Keyword(s):  
Case Report ◽  
Urinary Tract ◽  
Soft Tissue ◽  
Literature Review ◽  
Soft Tissue Sarcomas ◽  
Heterogeneous Group ◽  
Men 2

Urethral tumors are rare and aggressive. They usually affect men (2:1) and occur more commonly in white (85% of cases). Soft tissue sarcomas are a heterogeneous group of tumors that arise from embryonic mesoderm. It represents 1% of all cases of urinary tract malignancies and rarely primary affect the ureter. We report a case of male urethral sarcoma. To date, only two similar cases have been published in literature.

scholarly journals A Massive Posterior Neck Mass: Lipoma or Something More Sinister?

2013 ◽  
Vol 2013 ◽  
pp. 1-2 ◽  
Author(s):  
Matthew F. Ryan ◽  
Brandon Allen
Keyword(s):  
Cervical Spine ◽  
Soft Tissue ◽  
Literature Review ◽  
Soft Tissue Tumors ◽  
Neck Mass ◽  
Benign Soft Tissue Tumors ◽  
Posterior Neck ◽  
Slow Growing

Lipomas are slow-growing benign soft-tissue tumors which are typically asymptomatic and occur in approximately 1% of the population. A lipoma is considered to be of excessive size when it is greater than 10 cm in length (in any dimension) or weighs over 1000 g (Kransdorf (1995)). We describe a case of a man presenting with a giant posterior neck mass which greatly reduced the sagittal range of cervical spine. A discussion of the pathophysiology of lipomas and a literature review regarding giant lipomas versus malignancy follows.

scholarly journals Trabectedin in the treatment of soft tissue sarcomas: up to date data

2021 ◽  
Vol 13 (3) ◽  
pp. 16-26
Author(s):  
A. A. Fedenko ◽  
A. A. Tararykova
Keyword(s):  
Soft Tissue ◽  
Literature Review ◽  
World Wide ◽  
Advanced Disease ◽  
Malignant Tumors ◽  
Soft Tissue Sarcomas ◽  
Standard Chemotherapy ◽  
Modern Approach ◽  
Low Efficiency

Soft tissue sarcomas are a rare heterogeneous group of malignant tumors with mesenchymal nature. Soft tissue sarcomas accounts for less than 1 % of all cancers. Low efficiency of chemotherapy for soft tissue sarcomas, especially in advanced disease, is a burning issue. Trabectedin is one of the active agents approved for the treatment of advanced soft tissue sarcomas after the failure of standard chemotherapy. The article provides a literature review of the latest world-wide data of the effectiveness and role of trabectedin in the modern approach of soft tissue sarcomas treatment.

scholarly journals Pancreatic metastasis of dermatofibrosarcoma protuberans: a rare case

2020 ◽  
Vol 13 (1) ◽  
pp. e232614 ◽  
Author(s):  
Durga Sowgandhi Chilukuri ◽  
Prithviraj Premkumar ◽  
Balasubramanian Venkitaraman ◽  
Jagadesh Chandra Bose Soundararajan
Keyword(s):  
Case Report ◽  
High Risk ◽  
Soft Tissue ◽  
Local Recurrence ◽  
Rare Case ◽  
Dermatofibrosarcoma Protuberans ◽  
Metastatic Potential ◽  
Pancreatic Metastasis ◽  
Solitary Metastasis ◽  
Slow Growing

Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue malignancy which is locally aggressive, slow growing. It has a very low metastatic potential and has high risk of local recurrence. We report a 65-year-old man with recurrent DFSP of thigh with pancreatic metastasis. Apart from our patient, only four other cases of pancreatic metastasis of DFSP have been reported. Our patient had a solitary metastasis to pancreas and was treated with distal pancreaticosplenectomy. Outcome of the patient was good. We present this case report to emphasise that resection may be considered for solitary metastasis of DFSP and can be managed successfully.

scholarly journals Trabectedin Drug Holiday and Rechallenge in Soft Tissue Sarcomas: Report of 4 Cases and Literature Review

2019 ◽  
Vol 9 ◽  
Author(s):  
Francesco Pierantoni ◽  
Marco Maruzzo ◽  
Antonella Brunello ◽  
Benedetta Chiusole ◽  
Grazia Pusole ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Literature Review ◽  
Soft Tissue Sarcomas ◽  
Drug Holiday

scholarly journals A case of marantic endocarditis with systemic emboli in a patient with metastatic soft tissue sarcoma

2019 ◽  
Vol 6 (3) ◽  
pp. 6
Author(s):  
Daniel Alexander Reikher ◽  
Mark Feldman
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Malignant Tumors ◽  
Tissue Injury ◽  
Clinical Manifestations ◽  
Soft Tissue Sarcomas ◽  
Mass Effect ◽  
Metastatic Soft Tissue Sarcoma ◽  
Rare Group ◽  
Marantic Endocarditis

Clinical manifestations of cancer can be categorized as resulting from direct tissue injury from the primary tumor, distant metastatic spread, or aberrant biological activity, also known as a paraneoplastic syndrome. Soft tissue sarcomas are a rare group of malignant tumors of mesenchymal origin which typically present with direct tissue injury, exerting their harmful potential by compression and mass effect. We describe a rare case of an occult retroperitoneal soft tissue sarcoma presenting with marantic endocarditis. To date, there is a paucity of available medical literature relating sarcoma to marantic endocarditis.

Atypical Fibroxanthoma

2001 ◽  
Vol 110 (10) ◽  
pp. 985-987 ◽  
Author(s):  
Ishrat Hakim
Keyword(s):  
Elderly Patient ◽  
Case Report ◽  
Soft Tissue ◽  
Wide Local Excision ◽  
Fibrous Histiocytoma ◽  
Soft Tissue Sarcomas ◽  
Dermatofibrosarcoma Protuberans ◽  
Tissue Preservation ◽  
Atypical Fibroxanthoma ◽  
First Case

This is the first case report of atypical fibroxanthoma in the otolaryngology literature. Atypical fibroxanthoma is a rare fibrohistiocytic tumor that occurs on actinically damaged skin. The typical presentation is a nodular lesion in sun-exposed areas of the head and neck in an elderly patient. Differentiating atypical fibroxanthoma from other soft tissue sarcomas, such as dermatofibrosarcoma protuberans and malignant fibrous histiocytoma, can be difficult. Treatment should be wide local excision with a 1-cm margin. In cosmetically important regions in which tissue preservation is important, Mohs' surgery should be considered.

scholarly journals Lymph Node Metastasis after a Soft Tissue Sarcoma of the Leg: A Case Report and a Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
S. D. Nelen ◽  
F. J. Vogelaar ◽  
F. Gilissen ◽  
J. C. Van der Linden ◽  
K. Bosscha
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Lower Extremity ◽  
Distant Metastasis ◽  
Soft Tissue Sarcomas ◽  
Dermatofibrosarcoma Protuberans ◽  
Regional Lymph Nodes ◽  
Histological Types ◽  
Appropriate Treatment

Introduction. Soft tissue sarcomas (STSs) represent 1 percent of all adult malignancies and sarcomas only rarely spread to the regional lymph nodes.Case Presentation. We present a case of a woman with a dermatofibrosarcoma protuberans and a sarcoma not therwise specified of the lower extremity. The patient had no distant metastasis during follow-up, but did develop a regional lymph nodemetastasis (RLNM) in the groin. We reviewed the literature about RLNM in STSs.Discussion. Reviewing the literature we see that within specific histological types RLNM occurs as often as distant metastasis. Furthermore RLNM occurs in over 10% for specific histological types and in 24% of all patients with a soft tissue sarcoma of the lower extremity. Except for radical lymphadenectomy with a 5-year survival rate of 46% there is no appropriate treatment.Conclusion. The risk for a RLNM in certain histological types and anatomical locations might transcend the risk for a distant lung metastasis.

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