scholarly journals Chronic Osteomyelitis among Children Attending Orthopedic Services at Mbarara Regional Referral Hospital: Prevalence, Etiological Agents and Their Drug Susceptibility Patterns

Author(s):  
Tayebwa Edson ◽  
Kisitu Kyengera ◽  
Baguma Andrew ◽  
Bazira Joel

Background: This cross-sectional study was conducted to determine prevalence, causative agents and their drug susceptibility patterns of chronic osteomyelitis children among 766 children attending orthopedic services at Mbarara Regional Referral Hospital between October 2016 and June 2017. Methods: Seventy-four consented patients were consecutively enrolled and their demographic characteristics, clinical and radiological data collected. Superficial and deep bone pus swabs were collected and processed as per standard operative procedures. Susceptibility testing was done using the Kirby Bauer disc diffusion technique. Data was analyzed using Stata version 13.0. Results: The prevalence of children with COM was 9.7%.  The female: Male ratio was 1:1.2 with a mean age of 11 years. The most infected bone was the tibia followed by the femur. The common clinical presentations were chronic bone pain and discharging sinus tracts whereas the most imminent radiological features were sequestrum and involcrum. Pus swabs were taken off from both the discharging sinuses and the deep intra osseous abscesses for culture and sensitivity studies. The concordance rate of the microorganisms between the superficial and the deep swabs was 62.5%. Staphylococcus aureus was the most predominant microorganism isolated (85%). All the microorganism isolates were sensitive to gentamycin. However, all Staphylococcus aureus isolated were resistant to penicillin. Conclusion: Prevalence of Chronic osteomyelitis among children with orthopedic conditions presenting to MRRH is high. The isolated microorganisms are resistant to antibiotics we commonly use in our settings.

Author(s):  
Samson Mvandal ◽  
Godfrida Marandu

Early diagnosis of malaria and treatment seeking behavior play key role in controlling and preventing further complication related to malaria disease. Aim of this study was to determine the responses on early malaria diagnosis and treatment seeking behavior among outpatient clients attending at Sekou toure regional referral hospital in Mwanza, Tanzania. Methods: A cross-sectional study was conducted among outpatient client at Sekou-Touré regional referral hospital, convenient simple random sampling used and self-administered questionnaire were used to collect data and data was entered into Microsoft excel and then exported to SPSS version 25.0 for further analysis and presented on the percentages and table. The analysis of strength of relationships between categorical variables was conducted using the Chi-square test. A p-value of ≤ 0.05 was considered to be statistically significant. Results: A total of 192 respondents completed the study with a response rate of 97.6%. The study revealed that Most of the respondents about 90.6% stated they would seek treatment from health facility when symptoms appear. However, only 6.3% seek treatment within 24 hours of onset of illness (p= 0.017). Half of respondents (50.5%) experienced malaria symptoms in the past six months and only 30% seek for treatment at health facility. Preference of health facility, (51%) respondents were going direct to pharmacy to buy medicine for self-treatment. Overall, cost of service, time consumed and distance of health facility especially health center shows significant with such delay. Conclusion: A low proportion of malaria-suspected patients sought treatment within 24 h of fever onset compared to the national target. Distance from the health facility, cost of service and time consumed were found to be predictors of early treatment-seeking behavior for malaria. Strengthening strategies tailored to increasing awareness for communities about malaria, importance of going hospital and early treatment-seeking behavior is essential.


2020 ◽  
Author(s):  
Ismael Muhumuza ◽  
Abdulrahman Zeinul Lavingia ◽  
Bekson Tayebwa ◽  
Ahmed Abdulhussein Ahmed ◽  
Farhiya Mohammed Koriow ◽  
...  

Abstract Background : Post-caesarean wound sepsis is among the most common problem for patients who undergo caesarean section. It remains a common and widespread problem contributing to morbidity and mortality; this could be due to an increase in antimicrobial resistance. Determining the burden of wound sepsis and common bacterial pathogens can provide solution to prevent incidence and establish microbiological mapping. Aim: To determine prevalence, identify factors, common bacterial pathogens from post-caesarean wounds and antibacterial susceptibility pattern at Hoima Regional Referral Hospital. Methods : A cross-sectional study was conducted among post-caesarean mothers attending Hoima Regional Referral Hospital. Consecutive enrolment of 303 participants who consented to participate was done. Structured questionnaires were used to collect data on associated factors and wound swabs were done prior to bacterial culture. Antibacterial susceptibility pattern of isolated bacterial pathogens was determined by Kirby Bauer disc diffusion method. Data was analyzed using Stata 14.2. Results : The wound sepsis rate was 16.8%. Being educated, multiple vaginal examination, hygiene, previous caesarean sections and HIV seropositivity were all significantly and positively associated with post-caesarean wound sepsis (p<0.05). The most implicated bacteria was Staphylococcus aureus and was most susceptible to ciprofloxacin. Resistance was most exhibited against ciprofloxacin, gentamycin, ceftriaxone and cotrimoxazole especially by coliforms. Conclusions. The rate of caesarean wound sepsis is high at Hoima Regional Referral Hospital . Being educated, multiple vaginal examination, hygiene, previous caesarean sections and HIV seropositivity are possible risk factors for the condition. Staphylococcus aureus is the commonest organism isolated from exudates of septic wounds after caesarean section. Awareness amongst health workers and patients about these major factors is necessary so that management can be directed. Rational use of antibiotics by health workers is paramount to combat resistance in this setting.


Author(s):  
Esther Nambala ◽  
Jayne Byakika-Tusiime ◽  
Yahaya Gavamukulya

Aim: To determine nutritional knowledge and practices among patients with Non-Communicable Diseases (NCD) attending Mbale Regional Referral hospital, in Eastern Uganda. Study Design: A mixed methods cross sectional study design was used. Place and Duration of Study: Mbale Regional Referral Hospital among patients attending the NCD clinic from May to July 2017. Methodology: Two hundred sixty clients were recruited for the study. Quantitative data was collected through structured administered questionnaires. Quantitative data was analyzed at univariate, bivariate and multivariate levels. Chi square test and logistic regression were used to determine the association between nutrition knowledge and utilization. Qualitative data was coded first and summarized according to the themes. Results: The mean age of the respondents was 55 years (SD= 14) and hospital was the main source of nutrition information (n=156, 60%). Most respondents (n=156, 60%) had a high level of nutrition knowledge, however only 48.8% (n=127) were utilizing the knowledge. Those who had attained secondary level of education were 2.308 more likely to utilize the nutrition knowledge than those who had never studied P value of .028, 95CI (1.093-4.874). Those with tertiary education were even 9.261 times more likely to utilize the knowledge P value <.001 95CI (2.721-31.522). Those with adequate knowledge were about 1.6 times most likely to utilize the nutrition knowledge compared to those with inadequate knowledge level, however, with the adjusted odd ratio of 1.573 at 95% CI (0.923- 2.868) the results were not statistically significant (P value .098). Conclusion: NCD patients had adequate knowledge, with a few of them utilizing the knowledge. High education level was associated with better nutrition practices.


2021 ◽  
Author(s):  
◽  
Solomon Atuhaire

ABSTRACT Background: It is recommended to all mothers to undergo post-cesarean section self-care after delivery up to six weeks. However, many mothers return to Mbarara Regional Referral Hospital as a result of getting some complications related to cesarean section. The reasons why these mothers develop these complications are not clear and possible other practices performed by delivered mothers to solve their post-delivery challenges are not yet documented. Methods: The design of this study was a descriptive cross-sectional study design and a semi-structured questionnaire was used to collect quantitative data from the participants. Data were collected from 150 mothers admitted to the Maternity ward of Mbarara Regional Referral Hospital who formed the inclusion criteria and accepted to participate in the study. Data was captured using Microsoft excel and analyzed using Statistical Package for social sciences (SPSS). Results: The response rate in this study was 100%. The knowledge of post-cesarean section self-care among postpartum women at MRRH in Mbarara was poor as the majority of the participants 90(60%) reported to have never heard about Post Cesarean self-care while only 60 (40%) reported having ever heard about Post Cesarean self-care and no postpartum woman was fully aware of all the aspects of PCS and only 26% could talk of more than 2 aspects of the PCS. The findings of the study also revealed that 22% (33) of the postpartum women don't perform PCS at all. This shows a low practice of PCS among postpartum women. Conclusion and recommendations: Generally, in this study, the knowledge of post-cesarean section self-care among postpartum women at MRRH in Mbarara was poor, suggesting that these postpartum women are unaware of the value of this personal health promotion tool.


2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Winters Muttamba ◽  
Samuel Kyobe ◽  
Alimah Komuhangi ◽  
James Lakony ◽  
Esther Buregyeya ◽  
...  

Abstract Objective A cross-sectional survey involving 134 pulmonary TB patients started on TB treatment at the TB Treatment Unit of the regional referral hospital was conducted to ascertain the prevalence of individual and health facility delays and associated factors. Prolonged health facility delay was taken as delay of more than 1 week and prolonged patient delay as delay of more than 3 weeks. A logistic regression model was done using STATA version 12 to determine the delays. Results There was a median total delay of 13 weeks and 110 (82.1%) of the respondents had delay of more than 4 weeks. Patient delay was the most frequent and greatest contributor of total delay and exceeded 3 weeks in 95 (71.6%) respondents. At multivariate analysis, factors that influenced delay included poor patient knowledge on TB (adjOR 6.904, 95% CI 1.648–28.921; p = 0.04) and being unemployed (adjOR 3.947, 95% CI 1.382–11.274; p = 0.010) while being female was found protective of delay; adjOR 0.231, 95% CI 0.08–0.67; p = 0.007). Patient delay was the most significant, frequent and greatest contributor to total delay, and factors associated with delay included being unemployed, low knowledge on TB while being female was found protective of delay.


2021 ◽  
Vol 9 (07) ◽  
pp. 97-105
Author(s):  
Aremu A.B. ◽  
◽  
Afolabi I.B ◽  
Salaam M. Awunor N.S ◽  
Sulayman A.A ◽  
...  

Globally, Routine Medical checkup is known to be a preventive medicine that opens doors for assessment of well-being status of all individual and decreases the mortality and morbidity of different ailments in communities. attending health checkups may be one of the key reasons of controlling the predisposition and cause of much of the illness, suffering and early death related to chronic illnesses and condition. Its on this ground that this current study sought to elucidate further on factors determining the adherence of people to medical checkups. A descriptive cross-sectional study was carried out among 385 adult respondents attending Masaka regional referral hospital, in Uganda. A structured questionnaire involving open-ended and close-ended questionnaire was used and data was analyzed using SPSS version 26. Overall, 61.3% of study participants have ever heard of routine health check-ups citing hospitals (25.7%) as the most used source of the information. A prevalence of 43.4% represents the percentage of those who do routine health check-up and of which majority engage in only a general examination (14.5%). Overall, more than half of the respondents (56.6%) have never participated in routine health check-ups with their reported reasons of not feeling sick (25.97%). Factors like level of education, Employment, Occupational, exercise practices and level of awareness was statistically significant to uptake of routine heath checkup among the respondent at P< (0.005). Low health check-up rates may translate into inability to detect and intervene with early health challenges among respondents, and this is whereeffort is needed in ensuring that routine health check-up is encouraged especially during times when patients are healthy. There is need to strengthen government efforts and other concerned NGOs to put across specific sensitization programs about routine health check-ups on different media platforms and also utilize other social public means.


2021 ◽  
Vol 21 (2) ◽  
pp. 513-522
Author(s):  
Meseret Mitiku Gemechu ◽  
Tesfaye Assefa Tadesse ◽  
Getahun Negash Takele ◽  
Fithamlak Solomon Bisetegn ◽  
Yonas Alem Gesese ◽  
...  

Background: Hospital acquired infections (HAIs) are one of the global concerns in resource limited settings. The aim of the study was to determine bacteria profile and their antimicrobial susceptibility patterns among patients admitted at surgical and medical wards. Methods: A hospital based cross-sectional study was conducted from November 2016 to July 2017 in MaddaWalabu Uni- versity Goba Referral Hospital. Urine and wound swabs were processed and standard disk diffusion test was done to assess susceptibility pattern. Association among variables was determined by Chi-square test. Results: Among 207 patients enrolled, 24.6% developed HAI, of which, 62.7% and 37.3% were from surgical and medical wards, respectively. The male to female ratio was 1.5:1. The age ranged from 19 to 74 years with a mean of 41.65(±16.48) years. A total 62 bacteria were isolated in which majority of the isolates were gram negative bacteria. Most isolates were re- sistance to most of the antibiotics tested but sensitive to Ceftriaxone, Norfloxacin and Ciprofloxacin. Conclusion: Due to the presence of high level drug resistant bacteria, empirical treatment to HAI may not be effective. Therefore, treatment should be based on the result of culture and sensitivity. Keywords: Antimicrobial susceptibility patterns; bacterial profile; hospital acquired infections.


2022 ◽  
Author(s):  
Samson Peter Mvandal ◽  
Gotfrida Marandu

Abstract Background Early diagnosis of malaria and treatment seeking behavior play key role in controlling and preventing further complication related to malaria disease. Aim of this study was to determine the responses on early malaria diagnosis and treatment seeking behavior among outpatient clients attending at Sekou toure regional referral hospital in Mwanza, Tanzania. Methods A cross-sectional study was conducted among outpatient client at Sekou-Touré regional referral hospital, convenient simple random sampling used and self-administered questionnaire were used to collect data and data was entered into Microsoft excel and then exported to SPSS version 25.0 for further analysis and presented on the percentages and table. The analysis of strength of relationships between categorical variables was conducted using the Chi-square test. A p-value of ≤ 0.05 was considered to be statistically significant. Results A total of 192 respondents completed the study with a response rate of 97.6%. The study revealed that Most of the respondents about 90.6% stated they would seek treatment from health facility when symptoms appear. However, only 6.3% seek treatment within 24 hours of onset of illness (p= 0.017). Half of respondents (50.5%) experienced malaria symptoms in the past six months and only 30% seek for treatment at health facility. Preference of health facility, (51%) respondents were going direct to pharmacy to buy medicine for self-treatment. Overall, cost of service, time consumed and distance of health facility especially health center shows significant with such delay. Conclusion A low proportion of malaria-suspected patients sought treatment within 24 h of fever onset compared to the national target. Distance from the health facility, cost of service and time consumed were found to be predictors of early treatment-seeking behavior for malaria. Strengthening strategies tailored to increasing awareness for communities about malaria, importance of going hospital and early treatment-seeking behavior is essential.


Author(s):  
Abhineetha Hosthota ◽  
Trupthi Gowda ◽  
Rajini Manikonda

<p class="abstract"><strong>Background:</strong> Dermatophytoses are superficial mycoses which represents most common community health problem across the globe. Surveillance studies are required to understand the changing epidemiology and prevalence of causative agents to decide on appropriate therapy. This study aims to evaluate the clinical types, etiological agents and probable risk factors of dermatophytoses.</p><p class="abstract"><strong>Methods:</strong> It was a cross sectional study of 150 clinically suspected cases of dermatophytoses during six months. Sociodemographic details, clinical history and detailed examination were collected from all the subjects. Skin scrapings were sent to microbiology for direct microscopy and fungal culture.<strong></strong></p><p class="abstract"><strong>Results:</strong> Among the 150 subjects enrolled, males outnumbered females. Infection was mostly prevalent in the age group of 21-30 years (37.3%). Tinea cruris was the commonest clinical type (50%) followed by Tinea corporis (18.4%) and Tinea unguium (11.9%). Tricophyton rubrum was the aetiological agent isolated in majority (33%), followed by Tricophyton mentagrophytes (20%). The major risk factors of dermatophytoses were poor hygiene (32.1%), topical steroid usage (23.9%) and diabetes mellitus (20.1%).</p><p class="abstract"><strong>Conclusions:</strong> The present study has provided recent data on etiological agents of dermatophytoses and risk factors in our area. It is essential to develop measures for prevention, control of dermatophyte infections and establishment of therapeutic strategies.</p>


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