Vibratory stimulation in non-growing patients and its effect on the orthodontic tooth movement

<p><strong>Background:</strong> Objectives of the study were to determine the impact of vibratory stimulation in non-growing patients on the orthodontic tooth movement rate and to differentiate the orthodontic tooth movement rate in both experimental and control sides.</p><p><strong>Methods:</strong> 30 non-growing patients were selected for a split-mouth study with fixed appliance therapy orthodontic treatment undergoing bilateral first premolar extractions in maxillary arch. Type 1 active tiebacks were used to perform single canine retraction in all the patients. Vibratory stimulation was provided for 15 minutes daily with the help of Oral-B battery powered toothbrushes of 125 Hz frequency. Measurement was taken with calibrated digital vernier caliper clinically and OPG were taken at regular time intervals using grid method for the tooth movement calculation.</p><p><strong>Results:</strong> P value obtained by statistical calculation shows non-significant results in both experimental and control sides in non-growing patients.</p><p><strong>Conclusions:</strong> Cyclic loading in non-growing patients with fixed orthodontic appliance shows no change in orthodontic tooth movement in experimental and control group.</p>

Cyclic loading; its impact on the orthodontic tooth movement in growing patients: in vivo study

<p class="abstract"><strong>Background: </strong>The objective of the study was to evaluate the impact of vibratory stimulation on the orthodontic tooth movement rate in growing patients and to compare the orthodontic tooth movement rate in experimental and control sides.</p><p class="abstract"><strong>Methods: </strong>Split-mouth design study was done on 30 growing fixed appliance therapy orthodontic cases with bilateral first premolar extractions in maxillary arch. Individual canine retractions were performed in all the subjects with type-1 active tiebacks. Oral-B powered toothbrushes (125 Hz) were used to provide vibratory stimulation for 15 minutes per day (splits into 5 minutes thrice a day). The tooth movement was measured with calibrated digital vernier caliper clinically at various time intervals (T0, T1 and T2). OPG were taken at regular mentioned time intervals and grid method was used to calculate the tooth movement on OPGs.</p><p class="abstract"><strong>Results:</strong> Results were evaluated statistically and the p-value revealed significantly increased rate of tooth movement on experimental side as compared to control side.</p><p class="abstract"><strong>Conclusions: </strong>The high-frequency vibratory stimulation along with fixed orthodontic appliance can reduce treatment time expeditiously in growing patients. Powered toothbrushes can use successfully for providing vibrations to enhance the rate of tooth movement.</p>

The number of osteoblasts and osteoclasts in hypofunctional teeth during orthodontic tooth movement in rats

Background: When moved orthodontically, hypofunctional teeth will have a decreased tooth movement rate compared to normal teeth. This study aimed to determine the number of osteoblasts in the tension side and the number of osteoclasts in the pressure side of the hypofunctional teeth during orthodontic tooth movement. Method: 18 male Wistar rats were given a palatal coil spring application on the maxillary incisors. Rats were divided into two groups, the orthodontic group with normal occlusion (NO) and hypofunctional occlusion (HO). The number of osteoblasts on the tension side and osteoclasts on the pressure side on days zero (D0), five (D5), and 10 (D10) were tested with two-way ANOVA. Observations were made by hematoxylin eosin staining. Result: The results showed that the number of osteoblasts on the tension side of the HO group was the same at the NO group (p> 0.05). The number of osteoblasts on the tension side in the NO and HO groups at D5 was the same at D10 (p = 0.99), but significantly higher (p = 0.002), than D0. The number of osteoclasts on the pressure side in the HO group was significantly lower than the NO group (p <0.05). The number of osteoclasts in the NO D5 group was significantly higher than the other groups (p <0.05). Conclusions: The number of osteoblasts on the tension side was not affected by the hypofunctional state but decreased the number of osteoclasts on the pressure side during orthodontic tooth movement.

Effects of pentagamavunon-0 (PGV-0) as alternative analgesics on orthodontic tooth movement in rats

Introduction: Some analgesic drugs may have adverse effects on bone remodelling and, thus, on orthodontic tooth movement rate (OTM). GV-0 is synthesized by reacting vanillin and cyclopentanone catalyzed in acidic condition, and it has been revealed as a selective COX-2 inhibitor. This study was aimed to investigate the effect of pentagamavunon-0 (PGV-0), one of the curcumin analogues, on OTM. Methods: This study was conducted on 50 male Wistar rats (350-450 g) which were randomly divided into five groups (n = 10 each): 1) no treatment group (NT), 2) orthodontic treatment only (ORT), 3) ORT plus 0.4% sodium carboxymethyl cellulose (Na-CMC) analgesic carrier, 4) ORT plus 200 mg/kg BW Paracetamol (PCT) as the positive control, and 5) ORT plus PGV-0 (50 mg/kg BW (PGV-0). Results: Drug and day interaction was statistically significant on two-way ANOVA. Post-hoc analyses showed that OTM increased from day 3 to 7 in all orthodontic groups over the same distance (p>0.05). Maximum OTM was found on day 6, which was significantly farther than the distance on day 4. On day 7, OTM was less than on day 6. OTM in all orthodontic groups, including in the PGV-0 group, was higher than in the NT group (p<0.05). No differences was seen in OTM between PGV-0 group and other orthodontic groups (p>0.05). Post-hoc analysis (intra days) revealed that OTM in PGV-0 and other orthodontic treatment groups increased. Conclusion: After a single orthodontic force, PGV-0 does not inhibit tooth movement in rats from day 1 to day 7. Therefore, it is possible to develop PGV-0 as an alternative analgesics during orthodontic therapy.Keywords: Analgesic drug, orthodontics, tooth movement, curcumin.

Tooth movement rate and anchorage lost during canine retraction: A maxillary and mandibular comparison

ABSTRACT Objectives: To investigate the canine retraction rate and anchorage loss during canine retraction using self-ligating (SL) brackets and conventional (CV) brackets. Differences between maxillary and mandibular rates were computed. Materials and Methods: Twenty-five subjects requiring four first premolar extractions were enrolled in this split-mouth, randomized clinical trial. Each patient had one upper canine and one lower canine bonded randomly with SL brackets and the other canines with CV brackets but never on the same side. NiTi retraction springs were used to retract canines (100 g force). Maxillary and mandibular superimpositions, using cephalometric 45° oblique radiographs at the beginning and at the end of canine retraction, were used to calculate the changes and rates during canine retraction. Paired t-tests were used to compare side and jaw effects. Results: The SL and CV brackets did not show differences related to monthly canine movement in the maxilla (0.71 mm and 0.72 mm, respectively) or in the mandible (0.54 mm and 0.60 mm, respectively). Rates of anchorage loss in the maxilla and in the mandible also did not show differences between the SL and CV brackets. Maxillary canines showed greater amount of tooth movement per month than mandibular canines (0.71 mm and 0.57 mm, respectively). Conclusions: SL brackets did not show faster canine retraction compared with CV brackets nor less anchorage loss. The maxillary canines showed a greater rate of tooth movement than the mandibular canines; however, no difference in anchorage loss between the maxillary and mandibular posterior segments during canine retraction was found.