Right retrocolic intrasaccular duodenum: Is it a novel variant of isolated duodenal nonrotation? A case report

Background: Almost all of the studies on anomalies of the midgut rotation and fixation in the literature and related sections in textbooks were designed according to Dott's classification. Focusing only on common rotation anomalies has led to the exclusion and neglect of other rare variants. Isolated pure duodenal nonrotation is such a variant. Case Presentation: We report a case of an unusual form of isolated pure duodenal nonrotation, in a 3-day-old newborn presenting with bilious vomiting. Ultrasonographic examination revealed the sign of 'whirlpool'. When this finding was evaluated together with bilious vomiting, midgut volvulus was considered and the patient was operated on urgently. Peroperatively, it was observed that the jejunum entered between the leaves of the terminal ileum mesentery. Proximally, the duodenum was located posterior to the right colon in a "sack". This "sack" was surrounded by thick Ladd's bands laterally, mesentery of the ascending colon medially, the posterior surface of the cecum and ascending colon anteriorly, and by the posterior abdominal wall posteriorly. Conclusion: In isolated duodenal nonrotation, the duodenum may be completely retro-colic. Consequently, the duodenojejunal junction and the ileocecal region may almost overlap. Unlike isolated duodenal nonrotation cases, in the surgical treatment of this variant, separation of Ladd bands alone is not sufficient, additionally, the right colon should be placed in a nonrotation position and care should be taken not to kink the terminal ileum under the cecum.

EPIPLOIC APPENDAGITIS AS AN UNUSUAL CAUSE OF URGENT ABDOMINAL PATHOLOGY

Aim of the study is to present a clinical case of epiploic appendagitis as a rare acute abdominal pathology.Methods. This case demonstrates the prevalence of acute appendicitis symptoms in the clinical picture of the disease. During the operation was identified a necrotic changes in epiploic appendage of the ileocecal region with presence of secondary appendicitis.Result. The histological examination of the removed epiploic appendagitis gives a picture of tissues infarct with adipose necrosis and the presence of simple catarrhal appendicitis. It was received a normal postoperative course and a patient was discharged from hospital on the 8th day.Conclusion Epiploic appendagitis, due to the absence of pathognomonic symptoms, is an extremely difficult pathology for diagnosis. To establish the correct diagnosis, it is necessary to take into account a complex of data, including clinical and anamnestic, laboratory and instrumental diagnostic methods.

Gastroschisis Complicated by Colonic Atresia

Introduction: Gastroschisis with colonic atresia is a rare association. Due to its rarity and variation in presentation, no standardized surgical treatment option exists. Complicated gastroschisis is associated with a higher morbidity and mortality than intestinal atresia or gastroschisis alone. Methods: This is a case report of a neonate with congenital gastroschisis. On day of life 1, a silo was placed. On day of life 4, the upper portion of silo contents appeared more congested with dusky discoloration and the patient was oliguric. She was taken to the operating room for exploration. Results: The patient required resection of the terminal ileum and an atretic portion of the cecum due to necrosis. Four days later, primary closure of the gastroschisis defect was performed with creation of an end ileostomy. Elective ileostomy takedown was performed 5 months later. She returned to the operating room for anastomotic revision and gastrostomy tube placement for intestinal dysmotility and prolonged ileus. Tube feedings were discontinued 3 months post-operatively. Conclusions: Gastroschisis with intestinal atresia is associated with increased hospital length of stay, longer duration of parenteral nutrition, more severe intestinal dysfunction, increased surgical complications, and higher mortality than gastroschisis or intestinal atresia alone. With associated colonic atresia, loss of a significant length of bowel due to necrosis, including the ileocecal region, is almost unavoidable. An already compromised blood supply to the atretic bowel is further impaired by a tight abdominal wall defect and postnatal increases in gravitational force. Complicated gastroschisis remains a complex surgical challenge requiring further discussion.

Duodenal Duplication Cyst in adult male; An Extremely Rare Entity and a Diagnostic Pitfall leading to Whipple procedure

Introduction/Objective Whipple procedure is a complex, invasive operation and has high morbidity and mortality. It is the most commonly indicated treatment for treating malignant tumors, however, it can be also used for benign entities as well including biliary stricture, chronic pancreatitis, choledochal cyst, inflammatory pseudotumour, and duodenal angiodysplasia. Methods/Case Report We report a case of a 50-year-old man who presented with symptoms of gastric outlet obstruction. Esophagogastroduodenoscopy and CT scan showed an obstruction at the level of the second part of the duodenum with proximal dilation. Subsequently, a Whipple procedure was performed based on high clinical suspicion of duodenal cancer. Gross examination revealed a unilocular thick walled cyst (4.2 cm) in the duodenum. Histopathologic examination showed a cyst lined by duodenal mucosa with thick smooth muscle wall and focal ectopic gastric tissue. This was finally diagnosed as a duodenal cyst consistent with duplication cyst. Results (if a Case Study enter NA) NA Conclusion Duplication cysts are rare congenital abnormality predominantly diagnosed in infancy and childhood. They are most commonly located in the distal ileum, followed by the esophagus and ileocecal region, and are extremely rare in duodenum. Differential diagnosis includes choledochocele, pancreatic pseudocyst, and cystic tumors of the pancreas, mesenteric cysts, and duodenal diverticulums. Treatment options include total excision, cystojejunostomy, and endoscopic marsupialization but occasionally may lead to more invasive measures such as the Whipple procedure. Although duodenal duplication cysts can have variable clinical presentation and radiological findings, making preoperative diagnosis very challenging, it is still pertinent to be aware of this entity for the optimal patient care.

A Unique Case of Mantle Cell Lymphoma Masquerading as a Cecal Mass

Mantle cell lymphoma (MCL), a type of B-cell non-Hodgkin’s lymphoma, is a rare and aggressive disease with a poor prognosis due to its advanced presentation at diagnosis. It is characterized by a translocation in the Bcl-1 gene, which results in overexpression of cyclin D1. MCL is frequently seen in the form of multiple lymphomatous polyposis (MLP) in which innumerable polyps are observed in the gastrointestinal (GI) tract. In rare instances, MCL presents a single mass. The most common presentation involves male patients in their sixties, with generalized lymphadenopathy, extranodal involvement, and B symptoms (night sweats, fever, and weight loss). Endoscopic findings of MLP include cerebroid folding of the gastric mucosa and innumerable polyps extending from the duodenum to the large intestine and are reported in approximately 9% of all GI lymphomas. Less commonly, only 2–4% of GI malignancies present as a primary GI MCL as a single mass, usually in the stomach and ileocecal region in the intestine. Radiologic findings include lymphadenopathy, splenomegaly, multiple polyposis, or wall thickening with ulceration or mass formation. In most instances, advanced disease is found at diagnosis, for which 5-year survival ranges only from 26 to 46%, even when appropriate treatment is initiated. High mitotic rate, or Ki-67 index, is of prognostic value and is associated with poor prognosis. Treatment involves conventional chemo-immunotherapy consisting of R CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) or RB (rituximab and bendamustine), with the latter being better tolerated and associated with longer progression-free survival. Surgical resection is usually limited to patients in which complications are seen such as bleeding, perforation, or bowel obstruction. We present a unique case of a 70-year-old male with nonbilious, nonbloody emesis, and symptomatic anemia who was found to have a cecal mass consistent with MCL.

Regularities of endoscopic anatomy of the ileocecal intestine and their clinical signifi cance

The purpose of the study. Obtaining a set of new data, identifying patterns in the endoscopic anatomy of the ileocecal intestine and, on this basis, improving the diagnosis of its pathology.Materials and methods. The present study was conducted in 182 patients (men — 84, women — 98) who were examined and treated in the polyclinic and in the hospital of the Orenburg Regional Clinical Hospital. The age of all the examined patients is from 18 to 75 years. A set of methods was used: endoscopic (videocolonoscopy, videoileoscopy, examination of the mucous membrane in white light and in the NBI mode, the method of taking material for morphological examination), morphometric, morphological examination of biopsies, X-ray (irrigoscopy, irrigography), variational and statistical data processing.Results. In this work, a set of new data was obtained and patterns of the in vivo anatomy of the ileocecal department were revealed based on the results of colonoscopies. It was found that the endoscopic anatomy of the ileocecal region consists of individually variable parameters determined during intravital endoscopy: the shape, external structure and direction of the ileocecal valve, the internal relief and shape of the cecum, the projection and width of the tapes, the intraluminal morphometric parameters of the elements of the ileocecal valve and the cecum. Changes in the endoscopic anatomy of the ileocecal region in ulcerative colitis and Crohn’s disease were quantifi ed and presented. A rational set of studies based on endoscopic and X-ray anatomy is presented, which is necessary for improving the methods of colonoscopy, diagnosis of ulcerative colitis and Crohn’s disease, and various types of surgical treatment of pathology of this department.Conclusion. The new set of data obtained and the revealed regularities of the endoscopic anatomy of the ileocecal region expand the understanding of its clinical anatomy and the possibilities of in vivo study.

Abdominal CT manifestations in fish bone foreign body injuries: What the radiologist needs to know

Fish bone is one of the most common foreign body ingestions encountered in the emergency department. Fish bone perforations occur most commonly in segments with acute angulation like the ileocecal region and rectosigmoid junction and can present acutely with obstruction and free air or with chronic complications like abscess and sepsis. Radiologists should be familiar with the high-risk clinical scenarios, the CT appearance of radiopaque fishbones, and the spectrum of imaging findings related to gastrointestinal (GI) tract so as to direct management and timely referral to GI endoscopists and surgeons.

P208 Differentiating intestinal tuberculosis from Crohn’s Disease: External validation of a new nomogram

Background Intestinal tuberculosis (IT) poses a real problem of differential diagnosis with Crohn’Disease (CD). Indeed, the distinction between these two pathologies represents a real challenge for clinicians because of their multiple similarities. Based on simple biological, endoscopic and radiological criteria, A new nomogram was developed by Yao He et al. who would differentiate between the two diseases. Objective To validate externally this new nomogram in a series of patients with IT and CD. Methods We have collected retrospectively patients diagnosed with CD and IT in our center for a period 11 years old. Patients whose medical file included the data used in the nomogram have been included. The discrimination performance of the nomogram was evaluated by calculating the area under the ROC curve. Results Of the 76 included patients, 16 had one IT and 60 had one CD. The average age of patients with IT was 44.76 ± 19 years old. The most frequent revealing symptoms were subocclusive syndromes (n = 10) followed by abdominal pain (n = 8). Endoscopic lesions were located in the majority of cases in the ileocecal region (n = 12) and were dominated by the retracted aspect of the cecum (n = 5), transverse colonic ulcerations (n = 4) and valvular stenosis (n = 2). A tumor appearance was noted in two patients.The radiological images of the lungs suggestive of pulmonary tuberculosis were found only in two patients. Intradermal reaction (IDR) to tuberculin was positive in all cases where it was practiced. (n = 14). In ten cases, the diagnosis of ITwas made following bowel resection whose indications were diagnostic uncertainty (n = 4), acute bowel obstruction (n = 4) and suspected CD ileocecal refractory to medical treatment (n = 2). The discrimination of the nomogram analyzed by the ROC curve was 0.956 (95% CI [0.875; 1]). A threshold of 0.5 was associated with a sensitivity of 98.3%; a specificity of 92.8% and a positive and negative predictive value for the diagnosis CD of 98.3 and 92.8 respectively. Conclusion Although Tunisia is a country of strong endemicity for tuberculosis, intestinal localization seems infrequent and misdiagnosed. The nomogram applied seems to have excellent performance diagnose what could prevent resections intestinal for diagnostic purposes. However, studies multicenter prospective studies remain necessary for a large-scale validation.

Abdominal tuberculosis

ABSTRACT. The problem of detecting and diagnosing abdominal tuberculosis (TB) remains difficult. Recently in Ukraine there has been an increase in extrapulmonary TB, including abdominal TB. In modern conditions, this localization of TB is a manifestation of a generalized process in HIV-infected people. The most commonly diagnosed lesions of the lymphatic system and the peritoneum. The liver and spleen in abdominal TB is affected in every third case (32.3 %). In most patients, TB of the abdominal organs develops as a result of lymph-hematogenous dissemination from the primary focus, progresses through contact from the mesenteric lymph nodes to the peritoneum and intestines. According to statistics, TB of the mesenteric lymph nodes is most often diagnosed (70 %), the ileocecal region and the peritoneum are affected in 12 % of cases. The clinical picture of abdominal TB is polymorphic, there are no pathognomonic symptoms, therefore, the diagnosis of damage to the abdominal organs is the most difficult in the field of phthisiology. Diagnostic methods that are used: X-ray examination of the small intestine with a contrast agent, irrigoscopy, ultrasonography, computed tomography (CT), laparoscopy and laparotomy with sampling of material for morphological and bacteriological researches. The diagnostic value of CT with bolus enhancement is quite high: sensitivity is 95 %, specificity is 67.5 %. Given the difficulty of confirming the diagnosis of TB, in the case when the diagnosis is not confirmed culturally or histologically, and there is a reasonable suspicion of a specific lesion, which is based on clinical, endoscopic and radiological data, it is recommended to prescribe empirical treatment. Most patients respond positively to anti-TB treatment within 2 weeks. A clinical case of abdominal TB in an HIV-infected patient is described in this article.