The current article is a scholarly attempt to analyse, categorise, classify changes and challenges related to the cultural aspect in times of coronavirus outbreak, quarantine and social distancing, marking the big picture of the phenomenal processes occurring in the art spheres of the entire world. Through analysing prominent examples of the art mirroring the new reality, depicting atmosphere, environment, circumstances, positive and negative sides of pandemic time, employing different artistic signatures, manners, abstract and naturalistic approaches, sophisticated and simplified compositions, we uncovered the increasing role and function of the art in general, the high demand of cartoons, illustrations and rapid growth of digital art, attempts of nationalising the new dominating subject matter – idealised images of healthcare workers confronting the disease. The latter was visually represented by allegories, metaphors, symbols and embodiments, reaching the audience by its expressiveness. However, considering the fact, that the end of pandemic period remains unclear yet, our research has the notable perspective of continuity.