Rechargeable Flexible Paper Battery using PAV, PSSPEDOT Polymer

The main idea of this research is to design a rechargeable paper battery from local cheap and available materials. The practical part is represented by adding Polyvinyl alcohol (PVA) to conductive polymer (PSS PEDOT) with adding different mineral salts for then study the quantum of electrical conductivity and heat influence on electrical conductivity and acidity factors of the Electrolyte solution.The next step was to produce a rechargeable, flexible battery manufactured from regular cellulose paper, sulfone, and ionic solution.The measurements were made using modern laboratory devices to study the electrical properties, conductivity, resistance (Hall Effect), and voltage quantum of the ionic solution. Through the results we obtained, we noticed an increase in the conductivity of the ionic solution when adding mineral salts. The voltage quantum of one battery ranged between 0.3-0.3 volts, also several batteries were connected in series, and the result was 1.8 volts. Manufactured paper batteries can be recharged with a direct current source and recover their efficiency marked up 98-99%.

THE EFFECT OF THROMBIN IN THE SERUM-ADAPTED IONIC ENVIRONMENT ON THE INDUCTION OF EPILEPTIFORM FIRING ACTIVITY OF HIPPOCAMPAL CULTURED NEURONS

The mechanisms of epileptiform neuronal activity develop- ment under blood-brain barrier (BBB) dysfunction remains relevant in modern psychoneurology. In the present work we mimic some effects of BBB disruption in the culture of hip- pocampal neurons to examined the effect of serum-adapted ionic environment on the impulse activity of hippocampal neurons and the role of serum protein thrombin in induction of epileptiform neuronal activity. Using the whole-cell patch- clamp method under current-clamp mode we analyzed the spontaneous action potentials (AP) in the single hippocampal neurons. The changing of ionic extracellular neuronal environ- ment to such serum-adapted contributed to the development of epileptiform tonic activity of cultured hippocampal neurons and led to increase the average APs frequency by 65.1 ± 17.9% (n = 5) in neurons with spontaneous firing activity (FA) and to occurrence of tonic electrical activity (1.65 ± 0.4 s-1) in neurons without firing activity. Glutamate NMDA receptors significantly contribute to epileptiform tonic activity formation in neurons with FA, while their role in tonic activity providing in neurons without FA was insignificant. Thrombin (5 U/ml) in the serum-adapted ionic solution significantly enhanced of epileptiform activity in neurons with and without spontaneous FA: APs frequency increased in these neuronal groups by 117.3 ± 25.6% (n = 3) and by 61.8 ± 11.5% (n = 3), respective- ly, compared with that in the serum-adapted ionic solution only. Blockade of thrombin protease activated receptor 1 (PAR-1) by application of SCH 79797 (10 μm) canceled the thrombin’s effect in neurons without spontaneous FA, and significantly reduced such in neurons with FA. Therefore, the change of ionic extracellular neuronal environment to serum-adapted stimulates the occurrence of epileptiform activity in hippo- campal neurons, that is apparently associated with NMDA- receptors activation in neurons with FA. The proepileptiform action of thrombin was mostly mediated by PAR-1 activation. Thrombin-dependent regulation of the hippocampal single neurons firing activity involves the mechanisms different from the modulation of glutamate NMDA receptors in these cells.

Bio-mathematical analysis of electro-osmotically modulated hemodynamic blood flow inside a symmetric and nonsymmetric stenosed artery with joule heating

This is the first paper that explains electro-osmotically modulated hemodynamic inside a stenosed artery, considering both cases of symmetric and nonsymmetric shapes of stenosis. Blood is treated as an aqueous ionic solution. The energy equation incorporates viscous dissipation as well as Joule heating effects. Exact solutions are calculated for governing equations subject to “no slip” boundary conditions. These solutions are further discussed through graphical results. The flow pattern for symmetric and nonsymmetric stenosis is visualized by plotting streamlines for this flow problem.

Structure and dynamics of ions in dipolar solvent: A coarse-grained simulation study

We employ the coarse-grained molecular dynamics simulation to investigate the fundamental structural and dynamic properties of the ionic solution with and without the application of the electric field. Our simulations,...

Some Energy Issues for a Nanoscale Electrostatic Potential Well in Saline Solutions

An electrostatic potential well may be applied to trap and manipulate charged micro- and nanoparticles. An electrostatic potential well obtained from a certain charge distribution may be used to mimic the electrostatic interactions among biomolecules in live biosystems. In this study, we present a simulation study on the trapping performance of dipole clusters, which are arranged in 10 nm-sized, pentagon-shaped structures in a saline solution. The influence of electrostatic energy, entropy, and van der Waals interaction on the trapping performance of these nanostructures is then systematically calculated. The results show that the electrostatic potential well system demonstrated a moderate trapping capability, which could be enhanced using van der Waals interactions. The entropy significantly contributes to the trapping capability. This study offers some ideas for developing practical biomimetic electrostatic tweezers and nanorobots working in an ionic solution.