Mathematical models for blood flow in elastic vessels: Theory and numerical analysis

<p>In this thesis we study model equations that describe the propagation of pulsatile flow in elastic vessels. Since dealing with the Navier-Stokes equations is a very difficult task, we derive new asymptotic weakly non-linear and weakly-dispersive Boussinesq systems. Properties of the these systems, such as the well-posedness, and existence of travelling waves are being explored. Finally, we discretize some of the new model equations using finite difference methods and we demonstrate their applicability to blood flow problems. First we introduce the basic equations that describe f luid flow in elastic vessels and previously derived systems. We also review previously derived model equations for fluid flow in elastic tubes. We start with the description of the equations of motion of elastic vessel. Then wederive asymptotically Boussinesq systems for fluid flow in elastic vessels. Because these systems are weakly non-linear and weakly dispersive we expect then to have solitary waves as special solutions. We explore some possibilities by construction analytical solutions. After that we continue the derivation of the previous chapter. We derive a general system where the horizontal velocity is evaluated at any distance from the center of the tube. Special emphasis is paid on the case of constant radius vessels. We also derive unidirectional models and obtain the dissipative Boussinesq system by taking the viscosity effects into account. There is also an alternative derivation of the general system when considering the equations of potential flow. We show that the two different derivations lead to the same system. The alternative derivation is based on asymptotic series expansions. Then we develop finite difference methods for the numerical solution of the BBM equation and for the classical Boussinesq system studied in the previous chapters. Finally, we demonstrate the application of the new models to blood flow problems. By performing several numerical simulations.</p>

Mathematical models for blood flow in elastic vessels: Theory and numerical analysis

<p>In this thesis we study model equations that describe the propagation of pulsatile flow in elastic vessels. Since dealing with the Navier-Stokes equations is a very difficult task, we derive new asymptotic weakly non-linear and weakly-dispersive Boussinesq systems. Properties of the these systems, such as the well-posedness, and existence of travelling waves are being explored. Finally, we discretize some of the new model equations using finite difference methods and we demonstrate their applicability to blood flow problems. First we introduce the basic equations that describe f luid flow in elastic vessels and previously derived systems. We also review previously derived model equations for fluid flow in elastic tubes. We start with the description of the equations of motion of elastic vessel. Then wederive asymptotically Boussinesq systems for fluid flow in elastic vessels. Because these systems are weakly non-linear and weakly dispersive we expect then to have solitary waves as special solutions. We explore some possibilities by construction analytical solutions. After that we continue the derivation of the previous chapter. We derive a general system where the horizontal velocity is evaluated at any distance from the center of the tube. Special emphasis is paid on the case of constant radius vessels. We also derive unidirectional models and obtain the dissipative Boussinesq system by taking the viscosity effects into account. There is also an alternative derivation of the general system when considering the equations of potential flow. We show that the two different derivations lead to the same system. The alternative derivation is based on asymptotic series expansions. Then we develop finite difference methods for the numerical solution of the BBM equation and for the classical Boussinesq system studied in the previous chapters. Finally, we demonstrate the application of the new models to blood flow problems. By performing several numerical simulations.</p>

Gauged 2-form symmetries in 6D SCFTs coupled to gravity

We study six dimensional supergravity theories with superconformal sectors (SCFTs). Instances of such theories can be engineered using type IIB strings, or more generally F-Theory, which translates field theoretic constraints to geometry. Specifically, we study the fate of the discrete 2-form global symmetries of the SCFT sectors. For both (2, 0) and (1, 0) theories we show that whenever the charge lattice of the SCFT sectors is non-primitively embedded into the charge lattice of the supergravity theory, there is a subgroup of these 2-form symmetries that remains unbroken by BPS strings. By the absence of global symmetries in quantum gravity, this subgroup much be gauged. Using the embedding of the charge lattices also allows us to determine how the gauged 2-form symmetry embeds into the 2-form global symmetries of the SCFT sectors, and we present several concrete examples, as well as some general observations. As an alternative derivation, we recover our results for a large class of models from a dual perspective upon reduction to five dimensions.

Generalized vanishing theorems for Yukawa couplings in heterotic compactifications

Heterotic compactifications on Calabi-Yau threefolds frequently exhibit textures of vanishing Yukawa couplings in their low energy description. The vanishing of these couplings is often not enforced by any obvious symmetry and appears to be topological in nature. Recent results used differential geometric methods to explain the origin of some of this structure [1, 2]. A vanishing theorem was given which showed that the effect could be attributed, in part, to the embedding of the Calabi-Yau manifolds of interest inside higher dimensional ambient spaces, if the gauge bundles involved descended from vector bundles on those larger manifolds. In this paper, we utilize an algebro-geometric approach to provide an alternative derivation of some of these results, and are thus able to generalize them to a much wider arena than has been considered before. For example, we consider cases where the vector bundles of interest do not descend from bundles on the ambient space. In such a manner we are able to highlight the ubiquity with which textures of vanishing Yukawa couplings can be expected to arise in heterotic compactifications, with multiple different constraints arising from a plethora of different geometric features associated to the gauge bundle.

The alternative derivation procedure of equations of the law of the junction for the study of the p-n junction theory

The methodology that increases the student interest and provides modern knowledge to the study of the p-n junction theory has been proposed. It is based on two methods: increasing the interest of students using a new approach in derivation of equations of the law of the junction that allows obtaining more comprehensive knowledge about the operation of the p-n junctions and engaging students using the storytelling technique. The reaction of students to the lecture, obtained statistics on the student activity and the results of the student survey show that the proposed methodology allows increasing the student engagement in the p-n junction theory lectures.

Why Black-Scholes Equations Are Effective Beyond Their Usual Assumptions: Symmetry-Based Explanation

Nobel-Prize-winning Black-Scholes equations are actively used to estimate the price of options and other financial instruments. In practice, they provide a good estimate for the price, but the problem is that their original derivation is based on many simplifying statistical assumptions which are, in general, not valid for financial time series. The fact that these equations are effective way beyond their usual assumptions leads to a natural conclusion that there must be an alternative derivation for these equations, a derivation that does not use the usual too-strong assumptions. In this paper, we provide such a derivation in which the only substantial assumption is a natural symmetry: namely, scale-invariance of the corresponding processes. Scale-invariance also allows us to describe possible generalizations of Black-Scholes equations, generalizations that we hope will lead to even more accurate estimates for the corresponding prices.

A note on one-loop soliton quantum mass corrections

We develop an alternative derivation of the renormalized expression for the one-loop soliton quantum mass corrections in (1 + 1)-dimensional scalar field theories. We regularize implicitly such quantity by subtracting and adding its corresponding tadpole graph contribution and use the renormalization prescription that such added term vanishes with adequate counterterms. As a result, we get a finite unambiguous formula for the soliton quantum mass corrections up to one-loop order, which turns to be independent of the chosen regularization scheme.

Hamiltonian of new general relativity using differential forms

In a recent work we derived the kinematic Hamiltonian and primary constraints of the new general relativity class of teleparallel gravity theories and showed that these theories can be grouped in 9 classes, based on the presence or absence of primary constraints in their Hamiltonian. Here we demonstrate an alternative approach towards this result, by using differential forms instead of tensor components throughout the calculation. We prove that also this alternative derivation yields the same results and show how they are related to each other.