Modeling of Hierarchical Cathodes for Li-Air Batteries with Improved Discharge Capacity

The non-aqueous Li-air battery is considered to be a promising energy source for electric-vehicles owing to its ultrahigh theoretical power density. However, its commercialization is limited by the attained lower energy density value, which is mainly due to pore blockage and passivation which requires a more strategic design of the cathode. In this work, we have developed and validated a detailed one-dimensional continuum model of Li-Air battery that helps in examining the potential of hierarchical cathodes in guiding and enhancing the efficiency of ions transport and discharge product formation inside microstructures. The obtained results reveal the importance of reducing the tortuosity (shorten the path of oxygen transport) and increasing porosity at the airside of the hierarchical cathode, which improved discharge capacity at approximately 20.9 and 56%, respectively. The improved capacity is due to enhanced effective oxygen transport, impregnation of electrolyte, alignment of pores, and formation of permeable and low crystalline aggregates of Li2O2. Hence, strategies considering these insights can help in the design and fabrication of non-aqueous Li-air batteries with enhanced power density and capacity.

Bowls, vases and goblets—the microcrockery of polymer and nanocomposite morphology revealed by two-photon optical tomography

On the >1 µm scale the morphology of semicrystalline plastics like polyethylene or Nylon features spherulites, “shish-kebabs”, cylinddrites and other crystalline aggregates which strongly affect mechanical and other material properties. Current imaging techniques give only a 2D picture of these objects. Here we show how they can be visualized in 3D using fluorescent labels and confocal microscopy. As a result, we see spherulites in 3D, both in neat polymers and their nanocomposites, and observe how unevenly nanoparticles and other additives are distributed in the material. Images of i-polypropylene and biodegradable poly(lactic acid) reveal previously unsuspected morphologies such as “vases” and “goblets”, nonspherical “spherulites” and, unexpectedly, “shish-kebabs” grown from quiescent melt. Also surprisingly, in nanocomposite sheets spherulite nucleation is seen to be copied from one surface to another, mediated by crystallization-induced pressure drop and local melt-flow. These first results reveal unfamiliar modes of self-assembly in familiar plastics and open fresh perspectives on polymer microstructure.

Framboid Mineralogy

Framboids are dominantly made of pyrite. The limiting factors for other minerals forming framboids include the requirements of crystal habit, solubility, and natural abundances of the constituent elements for framboid formation. Detailed examination of reports of non-pyritic framboids reveal microcrystalline material within and associated with framboids (e.g., greigite) and sub-spherical crystalline aggregates (e.g., marcasite, chalcocite-digenite, magnetite). Framboids are sometimes observed replaced by other minerals. Pyrite framboids are often formed during the earliest stages of sedimentation or mineralization and therefore are subject to further reactions with later fluids. Minerals such as copper, cobalt, zinc, and lead sulfides often display framboidal forms that have replaced original pyrite framboids. Likewise, oxidation of pyrite under some conditions can produce iron (oxyhydr)oxide and iron sulfate framboids.

Search for Crystalline Species of Urinary Stones by Patients in the Region of Tissemsilt, Algeria

Urinary stones are among the most common diseases in the world and in Algeria as well, because it is a complex and multifactorial disease. The saturation of solutes in the urine is considered as the main stage of the deposition of crystals and their rapid growth and aggregation lead to the formation of stones in different places of the urinary system. It is the consequence of excessive urinary supersaturation causing renal complications such as lithiasis, nephrocalcinosis, acute or chronic renal failure which may progress to the terminal stage. The purpose of the study was to identify the most common different forms of crystals in the urine of patients for further measures to prevent more serious complications of crystalluria. Materials and methods. The study focused on all lithiasis patients of the age group "from 20 years to 84 years". Three-day urine samples were collected at different urology departments which were referred by urologists, during the period from February 06, 2020 to March 21, 2020. Being the best method, crystalluria was used to determine the types of crystals, their number and their growth. Three criteria must be met for the study of crystalluria to be clinically interpretable. They are the choice of patients according to their metabolic state; how long urine is stored after it is released, and the storage temperature. Results and discussion. Thanks to this study it was possible to characterize many types of crystals, including calcium oxalates, in particular monohydrate, which is considered as a risk factor for stone formation. Also, the urinary acid crystals indicate a specific environmental pattern in many patients. In addition to the calcium phosphate crystals resulting from microbial infections, the results showed pure crystalline aggregates which will inevitably lead to lithiasis. The microscopic examination of patient urine samples is the preferred method for optimal patient assurance with the cooperation of therapists and doctors in addition to the epidemiological study. Conclusion. The relatively high rate of recurrent lithiasis illustrates the current limits of preventive measures which can be penalized by the lack of patient attendance but whose reduced effectiveness primarily suggests a lack of knowledge of one or more fundamental determinants of the lithogenic process. The experimental part showed a diversity of crystals in the urine of patients, pure calcium oxalate monohydrate, which was noticed in the majority of the subjects analyzed. The detection, in crystalluria, of a single crystal of whewellite can therefore be considered as a marker for hyperoxaluria. Weddellite was more common in the urine of subjects under analysis

Stellate Genes and the piRNA Pathway in Speciation and Reproductive Isolation of Drosophila melanogaster

One of the main conditions of the species splitting from a common precursor lineage is the prevention of a gene flow between diverging populations. The study of Drosophila interspecific hybrids allows to reconstruct the speciation mechanisms and to identify hybrid incompatibility factors that maintain post-zygotic reproductive isolation between closely related species. The regulation, evolution, and maintenance of the testis-specific Ste-Su(Ste) genetic system in Drosophila melanogaster is the subject of investigation worldwide. X-linked tandem testis-specific Stellate genes encode proteins homologous to the regulatory β-subunit of protein kinase CK2, but they are permanently repressed in wild-type flies by the piRNA pathway via piRNAs originating from the homologous Y-linked Su(Ste) locus. Derepression of Stellate genes caused by Su(Ste) piRNA biogenesis disruption leads to the accumulation of crystalline aggregates in spermatocytes, meiotic defects and male sterility. In this review we summarize current data about the origin, organization, evolution of the Ste-Su(Ste) system, and piRNA-dependent regulation of Stellate expression. The Ste-Su(Ste) system is fixed only in the D. melanogaster genome. According to our hypothesis, the acquisition of the Ste-Su(Ste) system by a part of the ancient fly population appears to be the causative factor of hybrid sterility in crosses of female flies with males that do not carry Y-linked Su(Ste) repeats. To support this scenario, we have directly demonstrated Stellate derepression and the corresponding meiotic disorders in the testes of interspecies hybrids between D. melanogaster and D. mauritiana. This finding embraces our hypothesis about the contribution of the Ste-Su(Ste) system and the piRNA pathway to the emergence of reproductive isolation of D. melanogaster lineage from initial species.

Pseudo-morphogenesis in the shells of the Silurian brachiopods

The analysis of paleontological data, the study of mineral matter transformation involving live organisms in various rocks is important for the understanding of the events of the geological past. The aim of this work is to identify the bio-genic factor in the process of pseudo-morphogenesis in the shell sashes of the Early Silurian brachiopods from the car-bonate rocks of the Chernyshev Ridge. Structural and microscopic methods (Shimadzu XRD 6000; Fourier spectrometer InfraLum FT-02; JSM 6400 JEOL; VEGA3 TESCAN; MIN-8) were used to study quartz pseudomorphoses in the sashes of four shells of the Early Silurian brachiopods Borealis sр. of Pentamerida order from the carbonate strata of the Chernyshev Ridge. The salicification of the brachiopod shell walls resulted in the complete replacement of the original carbonate skeleton with a change in its structural organization. It is established that quartz is the main mineral component of the intra-shell material and secondary dolomite crystals and newly formed calcite aggregates. The paper discusses the participation of Early Paleozoic and modern cyanobacterial symbionts in the replacement of primary calcite with quartz and the formation of quartz crystalline aggregates on the shell walls. It is shown that quartz on the surface of shell sashes and in the intra-shell substance of brachiopods has undergone repeated transformations due to the combination of ancient and modern weathering processes.

A C. elegans Zona Pellucida domain protein functions via its ZPc domain

Zona Pellucida domain (ZP) proteins are critical components of the body’s external-most protective layers, apical extracellular matrices (aECMs). Although their loss or dysfunction is associated with many diseases, it remains unclear how ZP proteins assemble in aECMs. Current models suggest that ZP proteins polymerize via their ZPn subdomains, while ZPc subdomains modulate ZPn behavior. Using the model organism C. elegans, we investigated the aECM assembly of one ZP protein, LET-653, which shapes several tubes. Contrary to prevailing models, we find that LET-653 localizes and functions via its ZPc domain. Furthermore, we show that ZPc domain function requires cleavage at the LET-653 C-terminus, likely in part to relieve inhibition of the ZPc by the ZPn domain, but also to promote some other aspect of ZPc domain function. In vitro, the ZPc, but not ZPn, domain bound crystalline aggregates. These data offer a new model for ZP function whereby the ZPc domain is primarily responsible for matrix incorporation and tissue shaping.

Mineral Inventory of the Algares 30-Level Adit, Aljustrel Mine, Iberian Pyrite Belt, Portugal

Mining activity in Algares (Aljustrel Mine, Portuguese sector of the Iberian Pyrite Belt, IPB) stems prior to Roman times. As the orebody is vertical and relatively thin, mining was carried out mainly along underground adits (galleries). Nowadays, the deposit is considered exhausted and the area is being rehabilitated for a different use. The Algares +30 level adit intersects two volcanic units of the IPB Volcano-Sedimentary Complex. The massive sulphide and related stockwork zone are hosted by the Mine Tuff volcanic unit and are exposed in the walls of the gallery, showing intense hydrothermal alteration. Along the mine adit, the geological sequence is affected by strong oxidation and supergene alteration, giving rise to the formation of secondary minerals through the oxidation of the sulphides. The most common minerals found were melanterite (FeSO4·7H2O) and chalcanthite (CuSO4·5H2O), forming essentially massive or crystalline aggregates, ranging from greenish to bluish colours. Melanterite from the walls revealed to be Cu-rich by opposition to that from stalactites/stalagmites formed below the old ore storage silo revealing the low-copper-grade ores exploited underground. The mineralogy of the efflorescent salts was used to ascertain the processes involved in their formation, and moreover, the inventory of minerals is presented, as well as their principal characteristics.

Grguricite, CaCr2(CO3)2(OH)4.4H2O, a new alumohydrocalcite analogue

The occurrence and characterisation of a new member of the dundasite group are reported. Grguricite, ideally CaCr2(CO3)2(OH)4⋅4H2O, is the Cr analogue of alumohydrocalcite, CaAl2(CO3)2(OH)4⋅4H2O and occurs as lilac crusts of very fine-grained crystalline aggregates in the Pb–Ba–V mineralisation found at the Adeghoual Mine, Mibladen, Morocco (32°46′0″N, 4°37′59″W). The identification was based upon a close match with the powder X-ray diffraction data for alumohydrocalcite, the confirmation of anion components identified by Raman spectroscopy and the cation composition determined by electron-probe microanalysis. The empirical formula based upon 14 oxygen atoms per formula unit is Ca0.84Pb0.03Cr1.65Al0.39Mg0.02(CO3)2(OH)4⋅4H2O, with carbonate, hydroxyl and water contents set to those of the alumohydrocalcite stoichiometry. The fine-grained nature of the crystals (c. 0.5 μm × 0.1 μm × 5 μm) precluded a single-crystal X-ray study and both density and optical determinations. Grguricite is triclinic with space group P${\bar 1}$. Unit-cell parameters refined from the powder diffraction data are: a = 5.724(2), b = 6.5304(9), c = 14.646(4) Å, α = 81.682(1), β = 83.712(2), γ = 86.365(2)°, V = 537.8(2) Å3 and Z = 2. The five strongest peaks in the powder pattern are [dhkl, Å (I/Imax)(hkl)]: 6.222(100)(011), 3.227(87)(020), 6.454(63)(010), 2.883(58)(005, 023, 121) and 7.208(45)(002). The mineral is named after Australian geologist Ben Grguric.

A C. elegans Zona Pellucida domain protein functions via its ZPc domain

Zona Pellucida domain (ZP) proteins are critical components of the body’s external-most protective layers, apical extracellular matrices (aECMs). Although their loss or dysfunction is associated with many diseases, it remains unclear how ZP proteins assemble in aECMs. Current models suggest that ZP proteins polymerize via their ZPn subdomains, while ZPc subdomains modulate ZPn behavior. Using the model organism C. elegans, we investigated the aECM assembly of one ZP protein, LET-653, which shapes several tubes. Contrary to prevailing models, we find that LET-653 localizes and functions via its ZPc domain. Furthermore, the ZPc domain is inhibited by the ZPn domain and cleavage of the LET-653 C-terminus relieves this inhibition. In vitro, the ZPc, but not ZPn, domain formed crystalline aggregates. These data offer a new model for ZP function whereby the ZPc domain is primarily responsible for matrix incorporation and tissue shaping.