Children’s Negative Emotionality, Mothers’ Depression, and Parental Warmth in Predicting Children’s School Readiness in Low-Income Korean Families: The Role of Fathers’ Positive Involvement

This study examined how the longitudinal associations among children’s negative emotionality, mothers’ depressive symptoms, parental warmth, and children’s school readiness and whether the associations vary as a function of fathers’ positive involvement in low-income South Korean families. Participants were 399 families including mothers (Mage = 32.54 years at Time 1), fathers (Mage = 35.23 years at Time 1), and children (Mage = 38.92 months at Time 1; 50.5% boys) in the Panel Study on Korean Children. Results revealed that children’s negative emotionality was indirectly associated with their school readiness three years later, through its association with mothers’ depressive symptoms and warmth. Mothers’ warmth mediated the association between mothers’ depressive symptoms and children’s school readiness, and fathers’ warmth mediated the association between fathers’ positive involvement and children’s school readiness. Our findings revealed the family processes underlying children’s school readiness development in low-income Korean family contexts. Our findings also provide information useful for efforts to detect family risks and to establish family policies to promote low-income children’s school readiness.

Comparing the nutritional status of children and adolescents from North Korean defector families and South Korean families

ObjectiveThis study aimed to investigate the nutritional status of children and adolescents from North Korean defector (NKD) families who are currently living in South Korea (SK) and compared with the status of those from SK families.DesignA cross-sectional study comparing the prevalence of malnutrition, overweight and obesity between children and adolescents from NKD families and SK families.SettingChildren and adolescents from NKD families were interviewed face-to-face directly, whereas the data about those from SK families acquired by using 2017 Korea National Health and Nutrition Examination Survey. Their nutritional status were estimated using the 2017 Korean National Growth Charts for children and adolescents.ParticipantsThe total number of children and adolescents was 2136 consisting of 527 subjects from the NKD families and 1609 subjects from the SK families.ResultsThe overall prevalence of stunting, wasting, underweight, overweight and obesity in NKD group was 8.9%, 10.2%, 10.4%, 11.2% and 12.2% respectively, and 1.9%, 7.1%, 5.9%, 9.2% and 9.3%, respectively, in SK families. The NKD group showed significantly higher prevalence than SK group in stunting (p<0.001), wasting (p=0.014), underweight (p<0.001), obesity (p=0.041) but not in overweight.ConclusionsThe nutritional status of children and adolescents form NKD families was worse than that of those from SK families, and also higher prevalence of obesity.

Changes in Relationships in Bereaved Families: Perspectives of Mothers Who Lost a Child to Cancer

The loss of a child greatly affects the dynamics of interpersonal relationships in bereaved families. This study explored the relationships in bereaved Korean families from the perspectives of mothers after the death of a child due to cancer. We conducted in-depth interviews with 15 bereaved mothers of a deceased child with childhood cancer. Thematic analysis identified 12 subthemes related to bereaved mothers’ struggles in grief within three significant themes based on family relationships: (a) relationship with husband; (b) relationship with surviving child or children; and (c) relationships with extended family members. Findings highlight bereaved mothers’ need to build supportive family relationships while acknowledging bereaved family members’ different grieving styles and their own challenges in grieving the loss of a child.

Non-Syndromic Dentinogenesis Imperfecta Caused by Mild Mutations in COL1A2

Hereditary dentin defects can be categorized as a syndromic form predominantly related to osteogenesis imperfecta (OI) or isolated forms without other non-oral phenotypes. Mutations in the gene encoding dentin sialophosphoprotein (DSPP) have been identified to cause dentinogenesis imperfecta (DGI) Types II and III and dentin dysplasia (DD) Type II. While DGI Type I is an OI-related syndromic phenotype caused mostly by monoallelic mutations in the genes encoding collagen type I alpha 1 chain (COL1A1) and collagen type I alpha 2 chain (COL1A2). In this study, we recruited families with non-syndromic dentin defects and performed candidate gene sequencing for DSPP exons and exon/intron boundaries. Three unrelated Korean families were further analyzed by whole-exome sequencing due to the lack of the DSPP mutation, and heterozygous COL1A2 mutations were identified: c.3233G>A, p.(Gly1078Asp) in Family 1 and c.1171G>A, p.(Gly391Ser) in Family 2 and 3. Haplotype analysis revealed different disease alleles in Families 2 and 3, suggesting a mutational hotspot. We suggest expanding the molecular genetic etiology to include COL1A2 for isolated dentin defects in addition to DSPP.

The Multiple Dimensions of Family Meals and Their Associations with Family Strengths from the Perspective of Korean Mothers with School-Aged Children

The purpose of this study was to examine the association between family meals and family strengths (cohesion and flexibility) in Korean families with school-aged children. We focused on five dimensions of family meals: frequency, family rituals, communication, rules and roles, and perceptions. Our data came from 619 mothers who were married with at least one child in elementary school. Our multiple regression analyses showed that mothers reported higher levels of both cohesion and flexibility when they gave a higher priority to family meals, made family meals a ritual, had conversations on diverse topics during family meals, or experienced lower levels of meal-related stress. In addition, higher levels of family flexibility were found when a family had more structured rules related to family meals and the father more regularly participated in meal-related housework. This study contributes to the literature by understanding the roles of family meals from a multidimensional perspective.

Phenotypic Diversity of 15q11.2 BP1–BP2 Deletion in Three Korean Families with Development Delay and/or Intellectual Disability: A Case Series and Literature Review

The 15q11.2 breakpoint (BP) 1–BP2 deletion syndrome is emerging as the most frequent pathogenic copy number variation in humans related to neurodevelopmental diseases, with changes in cognition, behavior, and brain morphology. Previous publications have reported that patients with 15q11.2 BP1–BP2 deletion showed intellectual disability (ID), speech impairment, developmental delay (DD), and/or behavioral problems. We describe three new cases, aged 3 or 6 years old and belonging to three unrelated Korean families, with a 350-kb 15q11.2 BP1–BP2 deletion of four highly conserved genes, namely, the TUBGCP5, CYFIP1, NIPA2, and NIPA1 genes. All of our cases presented with global DD and/or ID, and the severity ranged from mild to severe, but common facial dysmorphism and congenital malformations in previous reports were not characteristic. The 15q11.2 BP1–BP2 deletion was inherited from an unaffected parent in all cases. Our three cases, together with previous findings from the literature review, confirm some of the features earlier reported to be associated with 15q11.2 BP1–BP2 deletion and help to further delineate the phenotype associated with 15q11.2 deletion. Identification of more cases with 15q11.2 BP1–BP2 deletion will allow us to obtain a better understanding of the clinical phenotypes. Further explanation of the functions of the genes within the 15q11.2 BP1–BP2 region is required to resolve the pathogenic effects on neurodevelopment.