One-pot Three-component Coupling Access to 1,2-Dihydropyrrolo[1,2-a]pyrazine-1-phosphonates: Multi-Functionalization of Pyrazine Unit

A new pyrrolo[1,2-a]pyrazine chemical space with a poly-substituted pyrazine unit was readily accessed by Sc(OTf)3-catalyzed one-pot three-component coupling of pyrrole derivative, amine, and trialkylphosphite under environment-friendly conditions. Formation of multiple...

A selective and easily recyclable dimer based on a calix[4]pyrrole derivative for the removal of mercury(ii) from water

A recyclable mercury(ii) selective dimer based on a calix[4]pyrrole derivative has been synthesised and characterised by mass and FT-IR spectrometry, Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray (EDX).

(Z)-1-Benzoyl-5-benzylidene-2-hydroxy-4-oxo-4,5-dihydro-1H-pyrrole-3-carbonitrile

The title compound, C19H12N2O3, obtained as an intermediate in the synthesis of a pyrrole derivative, is composed of a five-membered heterocycle with substituted groups via double or triple bonds as well as single bonds, without an asymmetric carbon atom. An intramolecular O—H...O link occurs. In the crystal, O—H...N hydrogen bonds link the molecules.

Novel Bifunctional Mesoporous Catalysts Based on Preyssler Heteropolyacids for Green Pyrrole Derivative Synthesis

In this paper, we report the synthesis of Preyssler heteropolyacids supported on mesoporous alumina in order to obtain materials with acid–base properties. A series of pyrrole derivatives were synthesized using a suitable procedure under solvent-free conditions. Using the alumina-supported material, more complex pyrrole derivatives can be obtained through a tandem one-pot process that involves the formation of 2-amino-3-cyano 4-H-chromenes by a multicomponent reaction and their subsequent conversion to pyrrole using a Paal–Knorr reaction.