Relative palatability and efficacy of brodifacoum-25D conservation rodenticide pellets for mouse eradication on Midway Atoll

Invasive mice (Mus spp.) can negatively impact island species and ecosystems. Because fewer island rodent eradications have been attempted for mice compared to rats (Rattus spp.), less is known about efficacy and palatability of rodenticide baits for mouse eradications. We performed a series of bait acceptance and efficacy cage trials using a standard formulation of brodifacoum-based rodenticide on wild-caught mice from Sand Island, Midway Atoll, to help inform a proposed eradication there. Mice were offered ad libitum brodifacoum pellets along with various alternative food sources, and a “no choice” treatment group received only bait pellets. Mortality in the no choice trial was 100%; however, when offered alternative foods, mice preferred the alternative diets to the bait, leading to low mortality (40%). Because there was concern that the bittering agent Bitrex® in the formulation may have reduced palatability, we conducted a subsequent trial comparing brodifacoum bait with and without Bitrex. Mortality in the with-Bitrex treatment group was slightly higher, indicating that the bittering agent was not likely responsible for low efficacy. Laboratory trials cannot account for the numerous environmental and behavioral factors that influence bait acceptance nor replicate the true availability of alternative food sources in the environment, so low efficacy results from these trials should be interpreted cautiously and not necessarily as a measure of the likelihood of success or failure of a proposed eradication.

“Publique Enemies to Mankind”

The origins of modern international law are frequently sought in the Early Modern period, and piracy has often been accorded a major role in this development, as well as in the emergence of an international system of states. The chapter highlights how international law developed through a process that Kempe calls “integration by exclusion.” Specifically, the author focuses on the piratical exploits and subsequent trial of John Cusack, executed in 1675. The case illustrates how accusations of piracy as a crime against all nations was a central element in the emergence of international law in Europe and in the establishment of England’s claim to be an effective global sea power. This demonstrated its ability to project its jurisdiction at sea far beyond the country’s shorelines.

“Indisputably Available”

Spurred on by Colson Whitehead’s Pulitzer Prize-winning novel The Nickel Boys (2019), which is set in Tallahassee, FL, during the 1950s and 1960s, this essay presents a close-up look at James Baldwin’s visit to Tallahassee in May 1960. Moving between Baldwin’s writings about the South, especially “They Can’t Turn Back,” published by Mademoiselle magazine in August 1960, and subsequent writing about the movement in Tallahassee, and checking off against Whitehead’s fictional treatment, we find a lattice of silences obscuring the names and contributions of Black women. Most importantly, we find that the historic case of the rape of Betty Jean Owens in May 1959, and the subsequent trial that summer, appears neither in Baldwin’s nor Whitehead’s writing about Tallahassee at the time. This essay establishes the missing names of Black women in the places marked and unmarked by Baldwin in his work at the time, and puts the case of Betty Jean Owens on the historical map where it belongs. In so doing, we figure issues of race, gender, sex, and violence for the ways they twist together, ways suppressed in historical (and even some contemporary) writing, ways crucial to our deepening consideration of Baldwin’s work and the history which he drew upon and to which he contributed so profoundly.

Cesarean delivery complicated with peripartum infection increases the risk of uterine rupture during subsequent trial of labour: A retrospective case-control study

Objective: To evaluate the relation between peripartum infection at first caesarean delivery to uterine dehiscence or rupture at the subsequent delivery. Design: Retrospective case-control study from March 2014 to October 2020. Setting: University-affiliated medical centre. Sample: Women with a prior caesarean delivery and proven dehiscence or uterine rupture diagnosed during their subsequent delivery. The control group included women who had a successful vaginal birth after Cesarean section without evidence of dehiscence or uterine rupture. Methods: We compared the rate of peripartum infection during the first Cesarean delivery and other relevant variables, between the two groups. We also analysed the type of infection correlated with uterine rupture or dehiscence. Main Outcome Measures: Rate of peripartum infection. Results: A total of 168 women were included, 71 with uterine rupture or dehiscence and 97 with successful vaginal birth after Cesarean section as the control group. The rate of peripartum infection at the first caesarean delivery was significantly higher in the study group compared to the control group (22.2% vs. 8.2%, p=0.013). Multivariate logistic regression analysis found that peripartum infection remained an independent risk-factor for uterine rupture at the subsequent trial of labour after Cesarean delivery (95% CI, P=0.018). We also found that endometritis had the highest correlation to uterine rupture (9.8% vs. 0%, p=0.02) Conclusion: Peripartum infection in the first caesarean delivery, may be an independent risk-factor for uterine rupture in a subsequent delivery. Compared to other infections, endometritis may pose the greatest risk for uterine rupture or dehiscence.

Smaller Than Expected

In two pre-registered studies, we investigated whether processes of imitative action regulation are facilitated after experiencing an episode of social exclusion. We reasoned that imitative action regulation effects should be more pronounced for participants who were socially excluded, providing them with an “automatic means” to socially reconnect with others. Participants played a virtual ball-tossing game to experimentally induce social exclusion or inclusion experiences. Subsequently, pairs of two participants engaged in an observational stimulus–response (SR) binding paradigm modeled after Giesen et al. (2014) : Participants observed color categorization responses in their interaction partner (trial n-1) and then executed (in)compatible responses in the subsequent trial (trial n), with observation and responding occurring in alternation. Stimulus relation (repetition vs. change) from trial n-1 to trial n was orthogonally manipulated. In both studies, stimulus-based retrieval effects of observationally acquired SR bindings were descriptively larger in socially excluded (compared with socially included) participants. However, none of the effects were statistically significant. Even a joint analysis of both experiments did not show the expected modulation. We discuss the implications of our findings for research on social exclusion effects on imitative action regulation processes.

Adaptive control of movement deceleration during saccades

As you read this text, your eyes make saccades that guide your fovea from one word to the next. Accuracy of these movements require the brain to monitor and learn from visual errors. A current model suggests that learning is supported by two different adaptive processes, one fast (high error sensitivity, low retention), and the other slow (low error sensitivity, high retention). Here, we searched for signatures of these hypothesized processes and found that following experience of a visual error, there was an adaptive change in the motor commands of the subsequent saccade. Surprisingly, this adaptation was not uniformly expressed throughout the movement. Rather, after experience of a single error, the adaptive response in the subsequent trial was limited to the deceleration period. After repeated exposure to the same error, the acceleration period commands also adapted, and exhibited resistance to forgetting during set-breaks. In contrast, the deceleration period commands adapted more rapidly, but suffered from poor retention during these same breaks. State-space models suggested that acceleration and deceleration periods were supported by a shared adaptive state which re-aimed the saccade, as well as two separate processes which resembled a two-state model: one that learned slowly and contributed primarily via acceleration period commands, and another that learned rapidly but contributed primarily via deceleration period commands.

Examining the effect of perceived performance-contingent gains, losses and errors on arithmetic

Gains and losses have previously been found to differentially modulate Executive Functions and cognitive performance depending on performance contingency. Following recent findings suggesting that random gains and losses modulate arithmetic performance, the current study aimed to investigate the effect of perceived performance-contingent gains and losses on arithmetic performance. In the current study, an arithmetic equation judgment task was administered, with perceived performance-contingent gain, loss, and error feedback presented upon each trial. The results from two experiments suggest that when perceiving gain and loss as performance-contingent, the modulation of arithmetic performance, seen previously under random contingency conditions was entirely eliminated. In addition, another type of feedback was examined in the context of an arithmetic task: post-error adjustments. When performance after error feedback was compared to performance after other aversive performance feedback such as loss signals, only errors, but not other aversive feedback, modulated performance in the subsequent trial. These findings further extend the knowledge regarding the influence of gain and loss situations, as well as errors, on arithmetic performance.

Primates' Food Preferences Predict Their Food Choices Even Under Uncertain Conditions

Primates’ food preferences are typically assessed under conditions of certainty. To increase ecological validity, and to explore primates’ decision making from a comparative perspective, we tested three primate species (Pan troglodytes, Gorilla gorilla gorilla, Macaca fuscata) (N = 18) in two food-preference tests that created different conditions of uncertainty. In the first, we showed subjects pairs of photographs of six foods in a randomized manner within each session, so subjects could not predict the next pairing and had to respond in accordance with their preferences. We found individual differences in subjects’ preference and differences in six subjects’ preferences when comparing their selections in this test to selections made when trials were blocked by food pairing (tested previously: Huskisson et al., 2020). In in each trial of the second test we paired the food stimuli with a ‘chance’ symbol, representing a random reward of one of the six foods. Across species, each subject’s propensity to select chance over the known food varied by food type: when the known option was highly preferred, subjects were less likely to select the chance symbol. Additionally, 61.11% of the subjects’ rates of selecting foods in the first test showed a positive trend with the rates of selecting the same foods under conditions of uncertainty here; three of these subjects’ selection rates were significantly correlated between tests. Finally, if the food chimpanzees received for selecting the chance symbol was a preferred food, they were more likely to select chance again in the subsequent trial.

Oscillatory brain activity links experience to expectancy during associative learning

Associating a novel situation with a specific outcome involves a cascade of cognitive processes, including selecting relevant stimuli, forming predictions regarding expected outcomes, and updating memorized predictions based on experience. The present manuscript uses computational modeling and machine learning to test the hypothesis that alpha-band (8-12 Hz) neural oscillations are involved in the updating of expectations based on experience. Participants learned that a visual cue predicted an aversive loud noise with a probability of 50 percent. The Rescorla-Wagner model of associative learning explained trial-wise changes in self-reported noise expectancy as well as alpha power changes. Both experience in the past trial and self-reported expectancy for the subsequent trial were accurately decoded based on the topographical distribution of alpha power. Decodable information during initial association formation and contingency report recurred when viewing the conditioned cue. Findings support the idea that alpha oscillations have multiple, simultaneous, and unique roles in association formation.

The Man Who Struck the Judge with a Fly Swatter: Justice and Performance in Contemporary Kazakhstan

This article investigates a series of events that occurred in Quaragandy, a postindustrial city in northern Kazakhstan in the mid-2010s. These events led to Evgenii Tankov, an established lawyer, hitting a judge, Arai Alshynbekov, with a fly swatter during a routine court session. This research demonstrates that Tankov's act was not a flash of rage or a real attempt to harm the judge. It was, instead, a calculated strategy in which a political statement was concealed if not sheathed within the form of a grotesque performance. Tankov knew he would be judged for disrespect towards the court: and yet he used his subsequent trial to demonstrate the moral and intellectual impasse of Kazakhstan's judicial system. This article claims that as a performance, Tankov's case is useful because it allows one to re-think the genre itself. Moreover, it argues that the form of the trial per se became a genre of political agency in contemporary Kazakhstan. As an example of political praxis, this case allows one to question the ways in which non-political actors produce and affirm their identities and create new forms of political agency in a reality in which political behavior is bounded by a postsocialist authoritarian state.