Oxidation Resistance of Double-Layer MoSi2–Borosilicate Glass Coating on Fiber-Reinforced C/SiO2 Aerogel Composite

An MoSi2–borosilicate glass coating with high emissivity and oxidation resistance was prepared on the surface of the fiber-reinforced C/SiO2 aerogel composite by the slurry method combined with the embedding sintering method under the micro-oxygen atmosphere. The microstructure and phase composition of the coatings with different MoSi2 contents before and after static oxidation were investigated. This composite material has both excellent radiating properties and outstanding oxidation resistance. The total emissivity values of the as-prepared coatings are all above 0.8450 in the wavelength of 300∼2,500 nm. Meanwhile, the as-prepared M40 coating also has superior thermal endurance after the isothermal oxidation of 1,200°C for 180 min with only 0.27% weight loss, which contributes to the appropriate viscosity of the binder to relieve thermal stress defects. This material has broad application prospects in thermal protection.

Physicochemical Properties of MoVTeNb Mixed Oxide Catalysts Synthesized using Different Vanadium Sources

The use of different vanadium sources in the synthesis of multi-metal MoVTeNb oxide catalysts has been investigated for their effect on the physicochemical properties of catalysts. Metal oxides were synthesized by slurry method assisted with a microwave irradiation. Vanadium pentoxide (V2O5), vanadyl sulphate (VOSO4) and ammonium metavanadate (NH4VO3) were used as the vanadium sources, respectively. X-ray diffraction (XRD) pattern showed the existence of orthorhombic (M1) phases in all catalysts. The catalyst prepared using V2O5 produced the highest formation of the phase. This was further supported by Inductive Couple Plasma-Atomic Emission Spectroscopy (ICP-AES), which showed that the V2O5 catalyst has the highest V: Mo ratio, mainly responsible for the high catalytic activity. Temperature Programmed Reduction in Hydrogen (H2-TPR) showed better reducibility for the catalyst when compared to the others. Temperature Programmed Reaction (TPRn) confirmed that the oxidants active for propane conversion into acrylic acid were originated from the lattice of the catalyst.

Analysis Of The Residual Red Soil Shear Test With The Slurry Method In The Regency Of Semarang

Residual soil is found in most areas with mountainous, hilly, and undulating topography. This soil is marked by red or brown color. This study aims to determine the physical and mechanical properties of soil in the original soil and residual soil conditions using the slurry method. Research objects were taken from residual red soil of The East Ungaran District, Bergas District, and Bawen District. Analysis of the physical and mechanical properties test shows that the soil sample is a type of clay with kaolinite constituent minerals and moderate swelling ability, and direct shear testing from locations L1, L2, and L3 obtained residual peak shear angles using the slurry method of 29,249 °; 31,341 °; 31,964 ° and constant residual shear angle value of 8,082 °; 8,138 °; 7,294 °, the value of the original soil shear angle has a value of 32.82 °; 31.44 °; 31.98. The higher the value of the plasticity index, the higher the value of the free swell. The relationship between the plasticity index and the value of the residual peak shear angle shows that the results of the peak shear angle and the plasticity index are still within the scope of standard deviation. The value of the constant residual shear angle with the slurry method is much smaller than the test result graph.

Pharmaceutical Cocrystals—A Review

The design and synthesis of pharmaceutical cocrystals have received great interest in the recent years. Cocrystallization of drug substances offers a tremendous opportunity for the development of new drug products with superior physical and pharmacological properties such as solubility, stability, hydroscopicity, dissolution rates and bioavailability. This short review summarizes this highly topical field, covering why the topic is of interest in pharmaceutical formulation, the definitions and practical scope of cocrystals, cocrystal preparation and characterization, a comparison of different (traditional and novel) methods for cocrystal formation and the implications for regulatory control and intellectual property protection. Traditionally, cocrystals can be prepared by solvent evaporation method, grinding, and slurry method, but every method has its limitations for certain conditions. The current trend for cocrystal formation uses sophisticated methods such as the hot melt extrusion method, spray-drying method, supercritical fluid technology and the newest method: laser irradiation. The purpose of the development of a new method is not only to overcome the limitation of traditional cocrystallization methods, but also to generate simpler steps and a continuous process for the production of the cocrystal product. This article provides a brief explanation of each method that can be used to generate pharmaceutical cocrystals as well as evaluation of cocrystals. This article also covers how the developing field of cocrystallization may impact the pharmaceutical intellectual property landscape.

Thermal Barrier Coatings for Molybdenum Produced Using Nanopowders

The molybdenum is one of the most important refractory metals used in aerospace industry. The main disadvantage of Mo is low oxidation resistance at elevated temperature and the using of protective coatings is necessary. In present article the new types of protective coatings produced by slurry method were developed. The slurries contained Al nanopowder and Si powder as well as non-organic binder (H2CrO4 and water). After immersion and drying the samples with slurries were heat treated at 1000°C in Ar atmosphere. The thickness of obtained coatings was in range 10-20 μm. The presences of phases form Mo-Al as well Mo-Si systems was analyzed using scanning electron microscopy. The developed coatings were used as a bond coat for ceramic layer produced by plasma spray physical vapour deposition method (PS-PVD). In this process the columnar ceramic layer contains yttria stabilized zirconia (YSZ) was obtained wit thickness above 100 μm. The obtained results showed that it is possible to obtain TBC coating on molybdenum contained Al-Si bond coat and outer YSZ ceramic layer. The proposed coating can be used in aerospace applications.

Development of Provesicular Nanodelivery System of Curcumin as a Safe and Effective Antiviral Agent: Statistical Optimization, In Vitro Characterization, and Antiviral Effectiveness

Curcumin is a natural compound that has many medical applications. However, its low solubility and poor stability could impede its clinical applications. The present study aimed to formulate dry proniosomes to overcome these pitfalls and improve the therapeutic efficacy of Curcumin. Curcumin-loaded proniosomes were fabricated by the slurry method according to 32 factorial design using Design-Expert software to demonstrate the impact of different independent variables on entrapment efficiency (EE%) and % drug released after 12 h (Q12h). The optimized formula (F5) was selected according to the desirability criteria. F5 exhibited good flowability and appeared, after reconstitution, as spherical nanovesicles with EE% of 89.94 ± 2.31% and Q12h of 70.89 ± 1.62%. F5 demonstrated higher stability and a significant enhancement of Q12h than the corresponding niosomes. The docking study investigated the ability of Curcumin to bind effectively with the active site of DNA polymerase of Herpes simplex virus (HSV). The antiviral activity and the safety of F5 were significantly higher than Curcumin. F5 improved the safety of Acyclovir (ACV) and reduced its effective dose that produced a 100% reduction of viral plaques. Proniosomes could be promising stable carriers of Curcumin to be used as a safe and efficient antiviral agent.

Fischer-Tropsch synthesis over Co/γ-Al2O3 catalyst loaded on ceramic monolith-structured substrate

Cobalt-based catalyst supported on γ-Al2O3­ was prepared by impregnation method and loaded on ceramic monolith-structured substrate by wash-coating slurry method. Physico-chemical properties of the catalysts were characterized by X-ray diffraction (XRD), Brunauer–Emmett–Teller (BET) specific surface area and H2 temperatured-programmed reduction (H2-TPR). Activity of the catalysts for Fischer-Tropsch synthesis was investigated in a tubular reactor in a temperature range of 200-275 oC at 20 bar and GHSV = 3000 h-1. Co/γ-Al2O3 catalyst loaded on ceramic monolith-structured substrate enhanced efficacy of Fischer-Tropsch synthesis by increasing and stabilizing CO conversion and C5+ selectivity, compared to Co/γ-Al2O3 powder catalyst.