An Invitation to Civic Dialogue

Those of us who have benefited from the climate of injustice need an invitation from others to join with them in changing our social climate to a climate of justice. The controversaries over national monuments opens the door to explore the question of who needs an invitation from whom and what white people need to learn in order to respond to the civilian invitation from others. The others include future generations, Syrian refugees, migrants at our Southern border, and personal invitations from People of Color. Personal invitations depend on our aptitude in engaging in dialogue, as is illustrated by an imaginary dialogue involving a white man and a black woman. Such dialogues can create the conditions for good conversations, and these conversation can move us toward a climate of justice—an ethical foundation for developing policies to protect our habitat for future generations.

Genetic Diversity and Spatiotemporal Dynamics of Chikungunya Infections in Mexico during the Outbreak of 2014–2016

Chikungunya virus (CHIKV) is an alphavirus transmitted by Aedes mosquitoes, which causes Chikungunya fever. Three CHIKV genotypes have been identified: West African, East-Central-South African and Asian. In 2014, CHIKV was detected for the first time in Mexico, accumulating 13,569 confirmed cases in the following three years. Studies on the molecular diversification of CHIKV in Mexico focused on limited geographic regions or investigated only one structural gene of the virus. To describe the dynamics of this outbreak, we analyzed 309 serum samples from CHIKV acute clinical cases from 15 Mexican states. Partial NSP3, E1, and E2 genes were sequenced, mutations were identified, and their genetic variability was estimated. The evolutionary relationship with CHIKV sequences sampled globally were analyzed. Our sequences grouped with the Asian genotype within the Caribbean lineage, suggesting that the Asian was the only circulating genotype during the outbreak. Three non-synonymous mutations (E2 S248F and NSP3 A437T and L451F) were present in our sequences, which were also identified in sequences of the Caribbean lineage and in one Philippine sequence. Based on the phylogeographic analysis, the viral spread was reconstructed, suggesting that after the introduction through the Mexican southern border (Chiapas), CHIKV dispersed to neighboring states before reaching the center and north of the country through the Pacific Ocean states and Quintana Roo. This is the first viral phylogeographic reconstruction in Mexico characterizing the CHIKV outbreak across the country.

Chemical Characteristics and Antioxidant Activity of Arctostaphylos uva-ursi L. Spreng. at the Southern Border of the Geographical Range of the Species in Europe

The bearberry (Arctostaphylos uva-ursi L. Spreng.) is a source of herbal material—bearberry leaf (Uvae ursi folium), which is highly valued and sought by pharmaceutical and cosmetic industries. For many years, leaves of this plant have been used in traditional medicine as a diuretic, antimicrobial, and anti-inflammatory agent for various diseases of the urogenital tract. The bearberry has also been proposed as a natural antioxidant additive due to the high contents of phenolic compounds in its leaves. The study was focused on characterization of the basic phytochemical composition and antioxidant activity of extracts derived from bearberry leaves collected from plants located at the southern border of the geographical range of the species in Europe. The investigated herbal material is characterized by a different chemical profile compared to the chemical profiles of bearberry found in other parts of the continent. Bearberry extracts from plants growing in two different habitat types—heathlands and pine forests showed a wide range of variation, especially in the concentration of hyperoside, corilagin, and methylartutin and the total flavonoid contents. In addition to arbutin, bearberry can be a valuable source of phenolic compounds, which are mainly responsible for the antioxidant properties of extracts. The high content of phenols and high values of antioxidant parameters indicate a high potential of bearberry leaves to be used as a powerful natural source of antioxidants in herbal preparations. Therefore, the A. uva-ursi populations can be a source of plant material for pharmaceutical, cosmetic, and food industries.

Elephantine

Elephantine. On Judeans in fifth century bce Southern Egypt In the fifth century bce a group of Judaeans lived as mercenaries in the Persian army on and around the island of Elephantine, as guardians of the southern border of the Persian empire and to shield the Persian trade interests. Documents show that these Judaeans had their own form of Yahwism. For almost 100 years they lived in peaceful coexistence with the Persian administration, the local Egyptian population, and with a dozen other ethnic groups settled on the island. From around 425 this pax persica was disrupted by local discords and the destruction by the priests of Khnum of vital elements of the Persian administration as well as the temple of Yahô. This contribution argues that the increasing urge of Egypt to abandon the Persian yoke and the influx of an extra group of Judeans – with a different form of Yahwism – around 420 created increasing tension between the different groups leading to the breakup of the peaceful cohabitation.

Molecular Characterization of Associated Pathogens in Febrile Patients during Inter-Epidemic Periods of Urban Arboviral Diseases in Tapachula Southern Mexico

Emerging and re-emerging vector-borne infections are a global public health threat. In endemic regions, fever is the main reason for medical attention, and the etiological agent of such fever is not usually identified. In this study, non-specific febrile pathogens were molecularly characterized in serum samples from 253 patients suspected of arbovirus infection. The samples were collected in the southern border region of Mexico from April to June 2015, and February to March 2016. ZIKV, CHIKV, DENV, leptospirosis, and rickettsiosis were detected by qPCR and nested PCR to identify flavivirus and alphavirus genera. The results indicated that 71.93% of the samples were positive for CHIKV, 0.79% for ZIKV, and 0.39% for DENV, with the number positive for CHIKV increasing to 76.67% and those positive for ZIKV increasing to 15.41% under the nested PCR technique. Leptospira Kmetyi was identified for the first time in Mexico, with a prevalence of 3.16%. This is the first report of ZIKV in Mexico, as well the first detection of the virus in early 2015. In conclusion, the etiological agent of fever was determined in 94% of the analyzed samples.

The Slovak Question in Foreign Policy Vision of the Second Rzeczpospolita Authorities (1938 – March 1939)

The Polish authorities had a negative attitude towards the central government of the Czechoslovak Republic at that time. Therefore, the Polish reprezentatives were in active contact with the opposition Glinka Slovak People’s Party. They had a number of common ideological values such as Slavic reciprocity, Catholicism, Anti-Bolshevism, and positive assessment of authoritarianism. The Polish politics assured that Warsaw supports state-building plans of the Slovak leaders and solemnly welcomed their delegation to Poland in May 1938. Polish-Slovak relations were marked by contradictions during and shortly after the Munich crisis. The Slovaks suggested state association and submitted a declaration on the Polish-Slovak union. But they did not receive an answer, so they agreed with the Prague government about granting Slovakia autonomy. The Polish authorities expected more pronounced separatism from the Slovaks. Warsaw made territorial claims for Slovak lands in the area of Spis and Orava because Poles wanted to push indecisive oppositionists. The ultimate form of the demands and the forceful nature of Polish actions demonstrated the real content of Warsaw’s policy towards Slovakia. These events resulted to the improvement of Czech-Slovak relations within the framework of Post Munich Czechoslovakia and also led to the appeal of Slovak politicians to Germany. Both sides tried to improve the atmosphere of bilateral relations during the winter of 1938-1939. Meetings of delegations were organized for discuss different ways to intensify positive cooperation. An influence of Nazi Germany was increasing in the region at that time. So, the realization of the danger, posed by Germans, was the main factor to Polish-Slovak rapprochement. In early March, Berlin organized a campaign to put pressure on Slovak politicians and persuaded them to secession. They tried in vain to put forward a Polish counterweight. The declaration of independence of Slovakia according to the German scenario marked the strategic failure of Polish foreign policy, because the southern border of the state became a zone of potential danger

A highly endemic area of Echinococcus multilocula is identified through a comparative re-assessment of prevalence in red fox (Vulpes vulpes), Alto Adige (Italy: 2019-2020)

Background: Surveillance of E. multilocularis at the edge of its range is hindered by fragmented distributional patterns and low prevalence and burden in definitive hosts. Thus, tests with adequate levels of sensitivity are especially important for discriminating between infected and non-infected areas. Aim: We reassessed the prevalence of E. multilocularis at the southern border of its distribution in Alto Adige (Italy), to improve surveillance in wildlife and provide more accurate estimates of exposure risk. Methods: We compared results from the diagnostic test currently implemented for surveillance (based on Coproscopy+Multiplex PCR - CMPCR), against a real-time quantitative PCR (qPCR) for 235 fox faeces collected in 2019-2020. The performances of the two tests were estimated using a scraping technique (SFCT) as the gold standard applied to the small intestines of a subsample (n=123) of the same hosts. True prevalence was calculated and sample size required by each faecal test for the detection of the parasite was then estimated. Results: True prevalence of E. multilocularis in foxes (14.3%) was definitely higher than reported in the last decade (never >5% from 2012 to 2018). The qPCR also had a higher sensitivity (83%) compared to CMPCR (21%). Agreement with the gold standard was far higher for qPCR (0.816) than CMPCR (0.298) as well, determining a smaller sample size required to detect the disease. Conclusions: Alto Adige should be considered a highly endemic area. Surveillance at the edges of E. multilocularis distribution should adopt qPCR diagnostics on definitive hosts on a small geographic scale.

The Metrics of Seto Choral Laments in the Context of Runosong Metrics

The aim of this paper is to get an overview of the lament metrics in Seto oral song tradition, which belongs to the southern border area of the Finnic song tradition, and the placement and historical development of lament metrics in the framework of the whole Seto oral song tradition. In the paper the metrical structures of two main genres of Seto choral laments – choral bridal laments and death laments – are analysed that share common features with solo laments and are similar to the structures of Seto runosongs. Metrical structures of the laments are detected based on sound recordings, taking into account the linguistic structure of the lines and the varied realization of it in a musical performance rhythm. The analysis showed that laments’ metrics where 5-unit end structures play an important role, differs the most from the main body of runosongs and is structurally more similar to a group of runosongs with refrains and varying line length. Outlining the development patterns of the metrical system of Seto songs, the influences of local unique musical tradition with varied rhythmic structures atypical of the most runosong area, specific functions of ritual song genres, historical changes in language, as well as possible external connections to early eastern and southern song cultures are highlighted.

Sociolinguistic Awareness of Spanish Speakers on the Mexican Border with Belize

The border society of Chetumal is studied in order to know how the speakers of this linguistic community conceive their ways of speaking Spanish in different situational contexts (home or work), before different people (employers, friends or subordinates) and with it get to check the degree of linguistic awareness they possess; that is, if the social boundaries present in their speech exist and are recognized as such by all speakers. This study is based on just over 100 questionnaires applied to the same number of Spanish-speakers born in Chetumal in 2019, who were registered according to the traditional sociolinguistic factors of age, sex, and socio-cultural level, the latter calculated basically on the individual's education index. The conclusions reflect the linguistic reality of Spanish speakers on the southern border of Mexico in which Caribbean and English elements are palpable in the lexical sector of the language.