Simulation of Cold Atmospheric Plasma Generated by Floating-Electrode Dielectric Barrier Pulsed Discharge Used for the Cancer Cell Necrosis

A numerical simulation of a pulsed floating electrode dielectric barrier discharge (FE-DBD) at atmospheric pressure, used for melanoma cancer cell therapy, is performed using a plasma model in COMSOL Multiphysics software. Distributions of electron density, space charge, and electric field are presented at different instants of the pulsed argon discharge. Significant results related to the characteristics of the plasma device used, the inter-electrodes distance, and the power supply are obtained to improve the efficiency of FE-DBD apparatus for melanoma cancer cell treatment. The FE-DBD presents a higher sensitivity to short pulse durations, related to the accumulated charge over the dielectric barrier around the powered electrode. At higher applied voltage, more energy is injected into the discharge channel and an increase in electron density and electric consumed power is noted. Anticancer activity provided by the FE-DBD plasma is improved using a small interelectrode distance with a high electron emission coefficient and a high dielectric constant with a small dielectric thickness, allowing higher electron density, generating reactive species responsible for the apoptosis of tumor cells.

Liquid-Crystal-Based Floating-Electrode-Free Coplanar Waveguide Phase Shifter with an Additional Liquid-Crystal Layer for 28-GHz Applications

A liquid-crystal (LC)-based floating electrode-free (FE-free) coplanar waveguide (CPW) phase shifter with an additional LC layer is demonstrated for the first time. An LC layer is overlain on the electrodes of the original model; this change increases the amount of electric flux that the proposed structure can confine in the tunable region, and thereby greatly increases the figure-of-merit (FoM) while maintaining the benefits of the simple coplanar structure. We simulated the variations in the phase shifter’s FoM, characteristic impedance, and driving voltage while sweeping the additional LC layer thickness up to 300 μm with each electrode condition at 28 GHz. In the case of electrode thickness variation, the FoM increased as electrode thickness increased, regardless of the presence of the additional LC layer. However, in the case of the signal electrode width variation, we obtained an opposite FoM tendency depending on the presence of the additional LC layer. This work shows the possibility of an efficient LC-based FE-free CPW phase shifter design for a given LC layer and electrode conditions.

Effect of Cold Plasma on the Levels Mineral Blood Components In Vivo

This study illustrates effect of cold plasma CAP on the mineral blood components in vivo. the mineral blood component (Ca, Na, Cl, K and Fe) are used. Floating Electrode-Dielectric Barrier Discharge (FE-DBD) system of probe diameter 4cm is used for this purpose, and variable voltage (0-20) kV and variable frequency (0-30) kHz, the output power was ranged from (10 - 70) W. the effect of cold atmospheric plasma on mineral blood is studied with different exposure durations (30,45,60) sec. As the plasma exposure duration increases, the calcium, potassium and iron components in the blood increased, while The sodium and chlorine elements decreased. These results give an indication of the cold plasma receptor to be used to treat many diseases related to mineral blood components.