B2C e-commerce logistics network optimization model

In this paper, considering the characteristics of e-commerce logistics and the problems arising from the construction of logistics network, based on the full investigation and research of the B2C electricity supplier operation mode, we have studied and summarized the research results of scholars at home and abroad aiming at the related problems, and summarized and summarized the methods and steps of logistics network optimization in the whole country. First, we established the logistics network structure.The definition of network level, node function and connection between nodes is carried out. Then, through the improved urban agglomeration order gravity model, the scope of self logistics city is screened. Finally, the link of logistics network structure is scheduled for completion with the goal of cost optimization.

B2C E-Commerce Logistics Network Optimization Model

In this paper, considering the characteristics of e-commerce logistics and the problems arising from the construction of logistics network, based on the full investigation and research of the B2C electricity supplier operation mode, we have studied and summarized the research results of scholars at home and abroad aiming at the related problems, and summarized and summarized the methods and steps of logistics network optimization in the whole country. First, we established the logistics network structure.The definition of network level, node function and connection between nodes is carried out. Then, through the improved urban agglomeration order gravity model, the scope of self logistics city is screened. Finally, the link of logistics network structure is scheduled for completion with the goal of cost optimization.

Pandora Papers complicate Lasso presidency in Ecuador

Significance The move follows the ‘Pandora Papers’ leak on October 3, which disclosed information on numerous political figures around the world. The revelations come during a period of tension between Ecuador’s executive and legislature. Lasso denies any wrongdoing and says he has nothing to hide. Impacts The Pandora Papers revelations will increase tensions between the executive and legislature and could derail planned economic reforms. The news will reduce the already slim possibility of the government reaching agreements with social movements, fuelling popular protests. Probes into Chilean President Sebastian Pinera will encourage Lasso’s opponents to push for a full investigation into his tax affairs.

Now Is Not the Time

Experts on Avicenna’s natural philosophy are in agreement that for Avicenna, time exists as the result of a now which flows and which through its flow produces time. Having been a prominent interpretation of Aristotle’s account of time in the Physics, the theory of the ‘flowing now’ was known to Avicenna from ancient and late ancient commentaries, and is mentioned in his most detailed discussion of time from his seminal work The Cure. It is, however, absent from all his other accounts of time and even within his argumentation in The Cure, there are strong, heretofore neglected reasons to believe that Avicenna ultimately did not adopt this idea. This article provides a full investigation of Avicenna’s theory of the now and investigates its position within the larger context of his temporal theory, arguing—against the current consensus—that for Avicenna, time is not produced by the now through its flow.

“Hold them or fold them:” evidence-based decisions to discontinue investigations of non-domestic minor violence

PurposeThe purpose of this paper is to demonstrate a “maintenance pathway” for ensuring a low false negative rate in closing investigations unlikely to lead to a clearance (detection).Design/methodology/approachA randomised controlled experiment testing solvability factors for non-domestic cases of minor violence.FindingsA random selection of 788 cases, of which 428 would have been screened out, were sent forward for full investigation. The number of cases actually detected was 22. A total of 19 of these were from the 360 recommended for allocation. This represents an improvement of accuracy over the original tests of the model three years earlier.Research limitations/implicationsThis study shows how the safety of an investigative triage tool can be checked on a continuous basis for accuracy in predicting the cases unlikely to be solved if referred for full investigations.Practical implicationsThis safety check pathway means that many more cases can be closed after preliminary investigations, thus saving substantial time for working on cases more likely to yield a detection if sufficient time is put into the cases.Social implicationsMore offenders may be caught and brought to justice by using triage with a safety backstop for accurate forecasting.Originality/valueThis is the first published study of a maintenance pathway based on a random selection of cases that would otherwise not have been investigated. If widely applied, it could yield far greater time for police to pursue high-harm, serious violence.

The Value of Quantitative Faecal Immunochemical Testing as a Prioritisation Tool for the Endoscopic Investigation of Patients With Iron Deficiency

Difficulty in providing endoscopy for patients with iron deficiency anaemia (IDA) during the COVID-19 pandemic has highlighted the requirement for a prioritisation tool. We aimed to test the validity of qFIT as a prioritisation tool in patients with iron deficiency and its ability to identify patients with advanced neoplastic lesions (ANLs). Data collected from patients referred with biochemically proven iron deficiency (ferritin ≤ 15 μg/L) and synchronous qFIT who underwent full gastrointestinal investigation within NHS Greater Glasgow and Clyde was analysed retrospectively. Patients who did not undergo full investigation, defined as gastroscopy and colonoscopy or CT colonography, were excluded. ANLs were defined as defined as upper GI cancer, colorectal adenoma ≥ 1 cm or colorectal cancer. Area under the curve (AUC) analysis was performed on qFIT results and outcome, defined as the presence of an ANL. AUC analysis guided cut-off scores for qFIT. Patients with a qFIT of <10, 10–200, >200, were allocated a score of 1, 2, and 3, respectively. A total of 575 patients met criteria for inclusion into the study. Overall, qFIT results strongly predicted the presence of ANLs (AUC 0.87, CI 0.81–0.92; P < 0.001). The prevalence of ANLs in patients with scores 1–3 was 1.2, 13.5, and 38.9% respectfully. When controlled for other significant variables, patients with a higher qFIT score were statistically more likely to have an ANL (qFIT score = 2; OR 12.8; P < 0.001, qFIT score = 3, OR 50.0; P < 0.001). A negative qFIT had a high NPV for the presence of ANLs (98.8%, CI 97.0–99.5%). These results strongly suggest that qFIT has validity as a prioritisation tool in patients with iron deficiency; both allowing for a more informed decision of investigation of patients with very low risk of malignancy, and in identifying higher risk patients who may benefit from more urgent endoscopy.

Fuzzy Evaluation of Agricultural Water Conservancy Facilities in Reuse

It is increasingly important to reuse the wastewater conservancy facilities, which can further promote the development of agricultural economy. The basis of full investigation and research on the wastewater conservancy facilities in rural areas by using fuzzy mathematics method. This paper constructs a hierarchy model to evaluate the reuse value of wastewater conservancy facilities. The model conducts empirical research on the wastewater conservancy facilities in a certain farmland. The research results show that the transformation of abstract research into quantitative research, a scientific and reasonable practical research model, is established, which can evaluate the research object well. The comprehensive evaluation value of a certain farmland is 0.608. The wastewater conservancy facilities in the farmland are in good condition and can be repaired by reconstruction; some economic benefits are obtained.

Severe Hyperphosphatemia in a Patient with Mild Acute Kidney Injury

Hyperphosphatemia may arise from various conditions including exogenous ingestion, extracellular shifts due to cell death or alterations in acid-base status, increased bone resorption, hormonal dysregulations leading to reduced renal excretion, reduced kidney function, or faulty measurement techniques. We herein present a case of a young pregnant woman who presented with mild acute kidney injury (AKI), invasive mucormycosis receiving liposomal amphotericin, and hyperphosphatemia out of proportion to the degree of kidney injury. While the patient was given routine phosphate-binding agent by her primary care team for presumed AKI-associated hyperphosphatemia, a full investigation by the renal consulting team for contributing factors other than kidney injury revealed that she actually had pseudohyperphosphatemia associated with the use of liposomal amphotericin. Erroneous treatment of pseudohyperphosphatemia may have been detrimental to this pregnant patient. A literature review for conditions associated with pseudohyperphosphatemia other than the use of liposomal amphotericin will be discussed.

Establishing a Smartphone Ambulatory ECG Service for Patients Presenting to the Emergency Department with Pre-Syncope and Palpitations

Background and Objectives: The Investigation of Palpitations in the ED (IPED) study showed that a smartphone-based event recorder increased the number of patients in whom an electrocardiogram (ECG) was captured during symptoms over five-fold to more than 55% at 90 days compared to standard care and concluded that this safe, non-invasive and easy-to-use device should be considered part of on-going care to all patients presenting acutely with unexplained palpitations or pre-syncope. This study reports the process of establishing a smartphone palpitation and pre-syncope ambulatory care Clinic (SPACC) service. Materials and Methods: A clinical standard operating procedure (SOP) was devised, and funding was secured through a business case for the purchase of 40 AliveCor devices in the first instance. The clinic was launched on 22 July 2019. Results: Between 22 July 2019 and 31 October 2019, 68 patients seen in the emergency departments (EDs) with palpitations or pre-syncope were referred to SPACC. Of those, 30 were male and 38 were female, and the mean age was 45.8 years old (SD 15.1) with a range from 18 years old to 80 years old. A total of 50 (74%) patients underwent full investigation. On the first assessment, seven (10%) patients were deemed to have non-cardiac palpitations and were not fitted with the device. All patients who underwent full investigation achieved symptomatic rhythm correlation most with sinus rhythm, ventricular ectopics, or bigeminy. A symptomatic cardiac dysrhythmia was detected in six (8.8%) patients. Three patients had supraventricular tachycardia (4%), two had atrial fibrillation (3%), and one had atrial flutter (2%). Qualitative feedback from the SPACC team suggested several areas where improvement to the clinic could be made. Conclusion: We believe a smartphone palpitation service based on ambulatory care is simple to implement and is effective at detecting cardiac dysrhythmia in ED palpitation patients.