Past efforts in e-Access, e-assistive, and e-inclusive technologies have largely focused on “parts of a problem.” That is to say, they have identified key tasks in day-to-day living and working or key elements in the experience of those with disability care and focused on the development of independent solutions for these specific tasks. Although this approach has yielded many successes, it may be time to stand back and take a look at the bigger picture. To the extent that systems have been discussed, the focus has been on technological systems. Typically, these systems are engineered systems that link otherwise weakly linked groups, such as doctors and carers with those cared for and their families or friends. In this chapter, the authors would like the reader to stand back and explore systems from a broader perspective, in particular from the human systems point of view.