PYXERA Global facilitates partnerships between public, private, and social sectors worldwide to create social impact projects that enrich lives and livelihoods, inclusively and sustainably. A nonprofit based in Washington, D.C., PYXERA Global has worked in over 90 countries—navigating economic, geographic, and political realities to find common ground between corporations, development agencies, governments, and nongovernmental organizations. In 2017, PYXERA Global opted to revitalize performance management (PM) practices. Previously “one size fits all,” goals were organized around operational efficiency, which ensured that staff followed consistent rules of engagement in getting the work done. Missing in the process were the organization’s three Strategic Pillars—Smart Growth, Impact, and Influence—which aligned daily work with the organization’s mission. By explicitly incorporating the pillars (the “what”) with mission- and client-centered imperatives, senior leaders shifted the paradigm. Similarly, replacing conventional competencies with Organizational Imperatives focused on the “how” to achieve goals. After 1 year of the new practice, staff reported deeper and more personal connections to what work gets done and how. Often cited is the Organizational Imperative, “No money, no mission,” a well-described imperative for employees that was disconnected from day-to-day activity. That imperative became an umbrella for financial responsibility at all levels; employees are clearer how budgeting is core to impactful engagements for clients, that attending to cost requirements and expense overruns reflects the staff’s commitment to the financial well-being of the organization. In addition, staff report having regular conversations about performance, solving problems, and removing obstacles and giving and receiving feedback more often.