New Approaches to Data Reduction in Mass Spectrometry

2009 ◽  
pp. 205-217
Author(s):  
William E. Wallace ◽  
Anthony J. Kearsley ◽  
Charles M. Guttman
Keyword(s):  
Mass Spectrometry ◽  
Data Reduction ◽  
New Approaches

scholarly journals Methods of the Analysis of Oxylipins in Biological Samples

Molecules ◽  
2020 ◽  
Vol 25 (2) ◽  
pp. 349 ◽  
Author(s):  
Ivan Liakh ◽  
Alicja Pakiet ◽  
Tomasz Sledzinski ◽  
Adriana Mika
Keyword(s):  
Mass Spectrometry ◽  
Biological Samples ◽  
Extraction Methods ◽  
The Body ◽  
New Approaches ◽  
Analysis Methods ◽  
Main Challenge ◽  
Comprehensive Information ◽  
Popular Subject ◽  
Derivatives Of

Oxylipins are derivatives of polyunsaturated fatty acids and due to their important and diverse functions in the body, they have become a popular subject of studies. The main challenge for researchers is their low stability and often very low concentration in samples. Therefore, in recent years there have been developments in the extraction and analysis methods of oxylipins. New approaches in extraction methods were described in our previous review. In turn, the old analysis methods have been replaced by new approaches based on mass spectrometry (MS) coupled with liquid chromatography (LC) and gas chromatography (GC), and the best of these methods allow hundreds of oxylipins to be quantitatively identified. This review presents comparative and comprehensive information on the progress of various methods used by various authors to achieve the best results in the analysis of oxylipins in biological samples.

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